Monday, 22 August 2005

09:00 Welcome addressBarbara Wollenberg, Nicole Rotter, Lübeck

Clinical Background

Chair: B. Wollenberg, R. Huss

09:10 Clinical point of view: What type of tissue do we need?

Frank Riedel, Mannheim

09:25 Tracheal surgery: Clinical requirementsStephan Lang, Luebeck

09:40 Surgical reconstruction of the auricle: Clinical state of the artKonrad Sommer, Luebeck

09:55 Transplants and implants in middle ear surgeryHans-Wilhelm Pau, Rostock

10:10 Laryngeal reconstructionGeorges Lawson, Yvoir

10:25 Discussion Cell Sources Chair: N. Rotter, S. Tiwari

11:00 Ear chondrocytes as a source for cartilage tissue engineering in different anatomic regionsGerjo van Osch, Rotterdam

11:15 Strategies for tissue engineering of salivary glands

Markus Bücheler, Bonn

11:30 Embryonic stem cell differentiation into chondrogenic cells

Jürgen Rohwedel, Luebeck11:45 Exocrine glands as a source for stem/progenitor cells Charli Kruse, Luebeck

12:00 Application of molecular imaging in stem cell tracking

Robert Krieg, Siemens, Erlangen

12.15 Discussion

Tissue Engineering in Head and Neck Surgery (Expertissues Workshop)

Biomaterials Chair: S. Lang, J. Kramer

14:00 Inflammation and immunityPio Conti, Chieti

14:30 New Biomaterials for application in head and neck surgery

Paul Hatton, Sheffield

14:50 Marine collagens – a new scaffold materialHolger Notbohm, Luebeck

15:10 Polysaccharide scaffolds for bone and cartilage repair

Paul Gatenholm, Chalmers

15:30 Discussion

Coffee break

Lunch break

19:30 Reception

Coffee break

1. Overview of regional programs08:30 German efforts in tissue engineering

Christof Stamm, Rostock

08:50 Tissue engineering in PortugalHelena Azevedo, Braga

09:10 The baltic tissue engineering perspectiveNureddin Ashammakhi, Finnland

09:30 Graduate studies in Europe Anselm Fremmer, German Research Foundation,

Bonn

2. Integrating European Research Efforts09:50 iPOOL: A digital tissue engineering platform for Europe

Jürgen Beier, Augsburg

10:10 Integrating postgraduate education in TEGustav Steinhoff, Rostock

10:30 Discussion

Tuesday, 23 August 2005

Coffee break

Novel tissue & cell products: From bench to bedside

11:15 Clinical stem cell applications: Requirements and perspectives

Ralph Huss, Munich

11:35 How a tissue engineering product gets to the patient

Michael Sittinger, Berlin

11:55 GMP grade cell manipulation: The cell factoryRosaria Giordano, Milano

12:15 What does the law say?Hans-Dieter Kleine, RostockVolker Kiefel, Rostock

12:45 DiscussionClinical grade cell processing

14:00 Centralized BMC preparationTorsten Tonn, BSD Hessen

14:20 BMC preparation for cardiovascular useWolfgang Rüdinger, Cytonet

14:40 Clinical grade cell selectionElmar Burchardt, Miltenyi Biotec

15:00 Long-term cell storageDietmar Egger, Vita34, Leipzig

15:20 Human myoblast preparation for transplantation

Maciej Kurpisz, Poznan

15:40 Discussion

European Education Concepts for Tissue Engineering (Joint Workshop)

Lunch break

Coffee break

20:00 Dinner

Clinical Cell Therapy for Myocardial Regeneration (Consortium Myocardial Repair Workshop)

Wednesday, 24 August 2005

Stem cell mobilization in cardiology

08:00 G-CSF in acute ischemia: Is it safe? Jonathan Hill, London

08:20 The FIRST-LINE-MI study Christoph A. Nienaber, Rostock

Intracoronary cell delivery

08:40 Intracoronary infusion of BMC: A multicenter trail

Andreas Zeiher, Frankfurt

09:00 The BOOST study Helmut Drexler, Hannover

09:20 The IACT studyBodo Strauer, Düsseldorf

09:40 Intracoronary delivery of CD133+ cellsJozef Bartunek, Aalst

10:00 CD133+ peripheral blood vs. marrow stem cellsRosaria Giordano, Milano

10:20 Discussion

Do we move too fast?

16:30 Public perception of cardiac cell therapyVolker Jacobs, DGRM

17:00 Does the experimental evidence justify clinical trials?

Ren Ke Li, Toronto

Myoblast delivery to the heart

11:00 Myoblast transplantation: History and milestones

Felipe Prosper, Pamplona

11:20 Clinical myoblast delivery methodsTomasz Siminiak, Poznan

11:40 Transendocardial myoblast deliveryHüsseyin Ince, Rostock

12:00 MAGIC-2 Study: Current statusHermann Reichenspurner, Hamburg

12:20 Discussion

Intramyocardial stem cell delivery

14:00 CABG & CD34+ BMSC injectionAmit Patel, Pittsburgh

14:20 CABG & CD133+ BMSC injectionChristof Stamm, Rostock

14:50 CABG & CD133+ PBSC injectionGiulio Pompilio, Monza

15:10 TMLR and cell therapyHans M. Klein, Düsseldorf

15:30 Mesenchymal stem cell: Is clinical use justified?Anthony D. Ho, Heidelberg

15:50 Discussion Coffee break

Lunch break

Coffee break

16:30 Clinical cell delivery systemsWarren Sherman, New York

The 3rd BALTIC STEM CELL Is endorsed and sponsored by:

Dear Colleagues,

We cordially invite you to participate in the 3rd BALTIC STEM CELL CONFERENCE, which will take place in the beautiful and exceedingly comfortable Kempinski Grand Hotel Heiligendamm.

This year’s conference will have two main focuses: The symposium “Tissue Engineering in Head and Neck Surgery” on Monday is supported by the EXPERTISSUES “Network of Excellence”. Advances in reconstructive head and neck surgery have revealed the vast potential of tissue engineering in otorhinolaryngology. This symposium links clinical insights in head and neck surgery with recent developments in biomaterial and stem cell technology. The following evening reception will allow participants from diverse backgrounds to exchange ideas and foster collaborations.

The joint workshop on Tuesday will address educational, industrial, and legal issues that are relevant for both tissue engineering and cell therapy approaches. Clinicians, scientists, and biotech companies together will work on accelerating the “bench-to-bedside” process to the benefit of our patients

Wednesday, the workshop “Clinical Cell Therapy for Myocardial Regeneration” will attempt to summarize the current clinical experience in the fast-moving field of cardiovascular cell therapy. Since numerous clinical trials are already on the way, there will certainly be enough substance for discussion. This is not to say that we have overcome the need for basic research, but to give clinicians who try to exploit the potential of regenerative therapy an opportunity to exchange their experience, to determine where they stand, and to reflect on where they want to go.

The 3rd BALTIC STEM CELL CONFERENCE will be held under the auspices of the ScanBalt BioRegion “network of networks”. ScanBalt is funded by the Nordic Innovation Center and the European Commission and promotes the development of a globally competitive meta-bioregion.

We look forward to welcoming you in Rostock-Heiligendamm!

Christof Stamm Nicole Rotter Tomasz SiminiakGustav Steinhoff Stephan Lang

Nureddin Ashammakhi, University of Tampere, Finnland

Helena Azevedo, Polymer Engineering, University of Minho, Portugal

Jozef Bartunek, OLV Hospital Aalst, Belgium

Jürgen Beier, ICU, Augsburg, GermanyMarkus Bücheler, ENT Surgery, University of Bonn, Germany

Elmar Burchardt, Miltenyi Biotec, Bergisch Gladbach, Germany Pio Conti, Immunology, University of Chieti, Italy

Helmut Drexler, Cardiology, MHH, Hannover, Germany

Dietmar Egger, Vita34, Leipzig, Germany

Anselm Fremmer, DFG, Bonn, Germany

Paul Gatenholm, University of Chalmers, Sweden

Rosaria Giordano, Hematology, University of Milan, Italy

Paul Hatton, University of Sheffield, UK

Jonathan Hill, Guy's, King's and St Thomas School of Medicine, London, UK

Anthony D. Ho, Hematology, University of Heidelberg, Germany

Ralph Huss, Pathology, Ludwig-Maximilians University of Munich, Germany

Hüsseyin Ince, Cardiology, University of Rostock, Germany

Volker Jacobs, DGRM / Technical University Munich, Germany

Volker Kiefel, Transfusion Medicine, University of Rostock, Germany

Hans M. Klein, Cardiac Surgery, University of Düsseldorf, Germany

Hans-Dieter Kleine, Hematology, University of Rostock, Germany

Robert Krieg, Siemens, Erlangen, Germany

Jan Kramer, Internal Medicin, University of Lübeck, Germany

Charli Kruse, Medical Molecular Biology, University of Lübeck, Germany

Maciej Kurpisz, Cardiology, Medical University Poznan, Poland

Stephan Lang, ENT, University of Lübeck, Germany

Georges Lawson, University Hospital of Louvain, Yvoir, Belgium

Ren Ke Li, Cardiac Surgery, University of Toronto, CanadaMarkus Bücheler, ENT, University of Bonn, Germany

Christoph Nienaber, Cardiology, University of Rostock, Germany

Holger Notbohm, Med. Mol. Biology, University of Luebeck, Germany

Gerjo van Osch, ENT Research, University of Rotterdam, Netherlands

Amit Patel, Cardiac Surgery, UPMC Pittsburgh, USA

Hans-Wilhelm Pau, ENT, University of Rostock, Germany Giulio Pompilio, Centro Cardiologico Monzino IRCCS, Italy

Felipe Prosper Cardoso, Clínica Univ. de Navarra, Pamplona, Spain

Hermann Reichenspurner, Cardiac Surgery, University of Hamburg

Frank Riedel, ENT Dept., University of Mannheim, Germany

Jürgen Rohwedel, Med. Mol. Biology, University of Luebeck, Germany

Nicole Rotter, ENT, University of Lübeck, Germany

Wolfgang Rüdinger, Cytonet, Hannover, Germany

Warren Sherman, Mount Sinai Medical Center, New York City, USA

Tomasz Siminiak, Cardiology, Medical University Poznan, Poland

Michael Sittinger, Charité, Berlin, Germany

Konrad Sommer, ENT, University of Lübeck, Germany

Christof Stamm, Cardiac Surgery, University of Rostock, Germany

Gustav Steinhoff, Cardiac Surgery, University of Rostock, Germany

Bodo Strauer, Cardiology, University of Düsseldorf, Germany

Torsten Tonn, BSD Hessen, Frankfurt, GermanyBarbara Wollenberg, ENT, University of Lübeck, GermanyAndreas Zeiher, Cardiology, University of Frankfurt, Germany

3rd BALTIC STEM CELL CONFERENCE

Faculty

3rd BALTIC STEM CELL CONFERENCE

University of LübeckMedical University of PoznanUniversity of Rostock

Organized by: Dept. of Cardiac Surgery, University of Rostock

ENT Dept., University of LübeckDept. of Cardiology, Medical University of Poznan

Tissue Engineering in Head and Neck

Surgery

Clinical Cell Therapy for Myocardial Regeneration

August 22 – 24, 2005

&

Kempinski Grand Hotel Heiligendamm, Germany

EUROPEAN NETWORK “MYOCARDIAL REPAIR ”&

“EXPERTISSUES” NETWORK OF EXCELLENCE

www.kempinski-heiligendamm.com

Janica SchützKlinik und Poliklinik für Herzchirurgie

Universität RostockD-18055 Rostock

Germany

email: jschuetz@med.uni-rostock.deFax: +49 381 494 6107

Phone: +49 381 494 6106

http://www.herzchirurgie-rostock.de/meetings/bssc2005http://www.uni-luebeck/hno/meetings/bssc2005

Organizing Secretariat

Venue

Christof Stamm, MDGustav Steinhoff, MDKlinik für HerzchirurgieUniversität RostockSchillingallee 3518055 RostockGermanychristof.stamm@med.uni-rostock.de

Scientific Secretariat

Please be aware that the number of participants is limited!

Please register prior to 14 July 2005 by mailing the enclosed postcard or by emailing the organizing

secretatriat at

jschuetz@med.uni-rostock.de

Registration fee: for 1 day Monday € 150,-Tuesday “Wednesday “

for 2 days Monday & Tuesday € 250,-Tuesday & Wednesday “

for 3 days Monday – Wednesday € 350,-

Reduced fee for students: €25,- per day

The registration fee covers conference attendance, lunch, and reception/dinner at the Kempinski Grand Hotel Heiligendamm.

Accomodation is not included

Bank transfer: “Baltic Stem Cell Conference”Deutsche Apotheker und ÄrztebankAcc/Kto: 020 580 10 79BLZ: 100 906 03IBAN: DE 10 300 601 01 020 580 10 79SWIFT/BIC Code: DAAE DE DD

Registration is valid once the registration fee has been received. Written requests for cancellation/refund must be received prior to 14 August 2005 and will be subject to a

€50,- cancellation fee. The program may be subject to changes

Registration

We have reserved a limited number of rooms at special rates in several hotels. Please contact the hotel directly and mention the

“Baltic Stem Cell Conference” . Please note that the reservation/cancellation rules of the respective hotel apply

Kempinski Grand Hotel Heiligendamm (€ 198,- – € 284,-)+49-38203-7400 www.kempinski-heiligendamm.com

Hotel Hübner, Warnemünde (€ 115,- - € 140,-)+49-381-54340www.hotel-huebner.de

Romantik Hotel, Bad Doberan (€ 90,- - € 100,-)+49-38203-63036

Aquamarin Hotel, Kühlungsborn (€ 60,- - € 80,-)+49-38293-4020www.hotel-aquamarin.de

Accomodation

Nicole Rotter, MDStephan Lang, MDHNO KlinikUniversität LübeckRatzeburger Allee 16023538 LübeckGermany

Nicole.Rotter@hno.uni-luebeck.de