Molecular Hydrogen BioMed App
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Molecular Hydrogen “An idea and pharmaceutical whose time has come” a food and nutraceutical ….
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Transcript of Molecular Hydrogen BioMed App
Molecular Hydrogen “An idea and pharmaceutical whose time has come” a food and nutraceutical ….
Molecular Hydrogen “An idea whose time has come” History
Historical applications:-Dirigible-until the Hindenberg Incident-Hydrogenation of oil-until vascular incidents-Inert and non toxic-useless in biomedical-Industrial gas for welding, petroleum refining,
and industrial chemical engineering-No historical medical uses prior to 1976
Molecular Hydrogen “An idea whose time has come”
The paradigm shifts
First hint of useful bio-activity:
Molecular Hydrogen “An idea whose time has come”
Early roadblocks
-Fyfe and Dole publish in AAAS “Science”-University sees hyperbaric hydrogen as insurance
liability ,“a bomb”, and orders apparatus to be deconstructed.
-No interest by medical or private industry to put molecular hydrogen into any product pipeline
-Inertness of molecular hydrogen questioned
Molecular Hydrogen “An idea whose time has come”
Safety to humans established
-Molecular hydrogen finds application in diving gas mixtures
-Still considered inert and biomedically useless-Safe long term use established….GRAS
Molecular Hydrogen “An idea whose time has come”hyperbaric H2 physiological effects
Molecular Hydrogen “An idea whose time has come”hyperbaric H2- 3 decades after seminal paper
Molecular Hydrogen “An idea whose time has come”
Hydrogen water
-Spas market special spring waters as therapeutic-H2 levels at homeopathic levels of 4-6 ppm-Easily dismissed as a mineral water with an added
placebo effect-Investigation begins to separate fact from fancy
Molecular Hydrogen “An idea whose time has come”Fringe medicine publishes data
Molecular Hydrogen “An idea whose time has come”Explosion of interest begins
Fig.?1 Illustration of the generation and scavenging systems of reactive oxygen species (ROS) in mitochondria. Superoxide radical anions (<ce:glyph name="rad"/> O<ce:inf loc="post"> 2</ce:inf> <ce:sup loc="post"> ?</ce:sup> ) are generated by the...
Shigeo Ohta
Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases
Biochimica et Biophysica Acta (BBA) - General Subjects Volume 1820, Issue 5 2012 586 - 594
http://dx.doi.org/10.1016/j.bbagen.2011.05.006
Molecular Hydrogen “An idea whose time has come”Future directions
-Hydrogen water at 4-6ppm has benefits-Lactulose produces H2 in gut but benefits are
skewed by poor bioavailability and catabolism by other microflora
-Inhaled H2 poses explosion hazards to dwellings, requires contracts and specialized equipment
Molecular Hydrogen “An idea whose time has come”
Future directions
-What if there were a simple way to increase bioavailabilty with no need for dispensing equipment or hazards of explosive gases?
-What if the delivery mode was marketable as food or food supplement that would slowly diffuse molecular hydrogen into body fluids, lungs and tissues of all descriptions?
Molecular Hydrogen “An idea whose time has come”
Future directions
INVENTOR : JOHNSON , MORRIS, F. , whose complete address is of SW34-01-16-W2, BOX 10, BEAUBIER , SASKATCHEWAN , CELL PHONE 701-240-9411, email [email protected] CANADA Method to use a stable foam composed of bubbles of various food/ supplement/ cosmetic/ pharmaceutical substances to increase the bio-availability of otherwise inert molecular hydrogen gas for medically useful health maintenance , health promotion, anti-aging and generalized disease process interference purposes in biological living systems in a manner which manages regulatory and insurance risks and impediments to mass commercialization.
Molecular Hydrogen “An idea whose time has come”
Future directions
Molecular Hydrogen “An idea whose time has come”
Future directions
Molecular Hydrogen “An idea whose time has come”
Future directions
-With the protection of a pending patent would a modest amount of capital launch products and be easily scaleable with contract manufacturing and find distribution channels?
-Would capital partner invest to expand the IP package to include beverages and cosmeceuticals and nutraceuticals?
Molecular Hydrogen “An idea whose time has come”
Future directions-Proposed manufacturing at Food Centre and POS
pilot plant in Saskatoon , Saskatchewan-Business offices in Saskatoon and Lake Alma ,
Saskatchewan-Equity and royalty swap for risk capital.
Morris Johnson, SW34-01-16W2, Box 10Beaubier, Sk., Canada, 701-240-9411
