Molecular hydrogen biomed-applications-888

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Molecular Hydrogen “An idea and pharmaceutical whose time has come” a food and nutraceutical ….

description

molecular hydrogen is a very simple yet never yet commercialized regenerative medicine agent. My patent seeks to create the economic infrastructure to support a broad range of applications based upon a solid base of evidence for efficacy as an anti-aging tool.

Transcript of Molecular hydrogen biomed-applications-888

Page 1: Molecular hydrogen biomed-applications-888

Molecular Hydrogen “An idea and pharmaceutical whose time has come” a food and nutraceutical ….

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Molecular Hydrogen “An idea whose time has come” History

Historical applications:-Dirigible-until the Hindenberg Incident-Hydrogenation of oil-until vascular incidents-Inert and non toxic-useless in biomedical-Industrial gas for welding, petroleum refining,

and industrial chemical engineering-No historical medical uses prior to 1976

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Molecular Hydrogen “An idea whose time has come”

The paradigm shifts

First hint of useful bio-activity:

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Molecular Hydrogen “An idea whose time has come”

Early roadblocks

-Fyfe and Dole publish in AAAS “Science”-University sees hyperbaric hydrogen as insurance

liability ,“a bomb”, and orders apparatus to be deconstructed.

-No interest by medical or private industry to put molecular hydrogen into any product pipeline

-Inertness of molecular hydrogen questioned

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Molecular Hydrogen “An idea whose time has come”

Safety to humans established

-Molecular hydrogen finds application in diving gas mixtures

-Still considered inert and biomedically useless-Safe long term use established….GRAS

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Molecular Hydrogen “An idea whose time has come”hyperbaric H2 physiological effects

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Molecular Hydrogen “An idea whose time has come”hyperbaric H2- 3 decades after seminal paper

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Molecular Hydrogen “An idea whose time has come”

Hydrogen water

-Spas market special spring waters as therapeutic-H2 levels at homeopathic levels of 4-6 ppm-Easily dismissed as a mineral water with an added

placebo effect-Investigation begins to separate fact from fancy

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Molecular Hydrogen “An idea whose time has come”Fringe medicine publishes data

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Molecular Hydrogen “An idea whose time has come”Explosion of interest begins

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Fig.?1 Illustration of the generation and scavenging systems of reactive oxygen species (ROS) in mitochondria. Superoxide radical anions (<ce:glyph name="rad"/> O<ce:inf loc="post"> 2</ce:inf> <ce:sup loc="post"> ?</ce:sup> ) are generated by the...

Shigeo Ohta

Molecular hydrogen is a novel antioxidant to efficiently reduce oxidative stress with potential for the improvement of mitochondrial diseases

Biochimica et Biophysica Acta (BBA) - General Subjects Volume 1820, Issue 5 2012 586 - 594

http://dx.doi.org/10.1016/j.bbagen.2011.05.006

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Molecular Hydrogen “An idea whose time has come”Future directions

-Hydrogen water at 4-6ppm has benefits

-Lactulose produces H2 in gut but benefits are skewed by poor bioavailability and catabolism by other microflora

-Inhaled H2 poses explosion hazards to dwellings, requires contracts and specialized equipment

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Molecular Hydrogen “An idea whose time has come”

Future directions

-What if there were a simple way to increase bioavailabilty with no need for dispensing equipment or hazards of explosive gases?

-What if the delivery mode was marketable as food or food supplement that would slowly diffuse molecular hydrogen into body fluids, lungs and tissues of all descriptions?

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Molecular Hydrogen “An idea whose time has come”

Future directions

INVENTOR : JOHNSON , MORRIS, F. , whose complete address is of SW34-01-16-W2, BOX 10, BEAUBIER , SASKATCHEWAN , CELL PHONE 701-240-9411, email [email protected] CANADA  Method to use a stable foam composed of bubbles of various food/ supplement/ cosmetic/ pharmaceutical substances to increase the bio-availability of otherwise inert molecular hydrogen gas for medically useful health maintenance , health promotion, anti-aging and generalized disease process interference purposes in biological living systems in a manner which manages regulatory and insurance risks and impediments to mass commercialization.

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Molecular Hydrogen “An idea whose time has come”

Future directions

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Molecular Hydrogen “An idea whose time has come”

Future directions

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Molecular Hydrogen “An idea whose time has come”

Future directions

-With the protection of a pending patent would a modest amount of capital launch products and be easily scaleable with contract manufacturing and find distribution channels?

-Would capital partner invest to expand the IP package to include beverages and cosmeceuticals and nutraceuticals?

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Molecular Hydrogen “An idea whose time has come”

Future directions-Proposed manufacturing at Food Centre and POS

pilot plant in Saskatoon , Saskatchewan-Business offices in Saskatoon and Lake Alma ,

Saskatchewan-Equity and royalty swap for risk capital.

Morris Johnson, SW34-01-16W2, Box 10Beaubier, Sk., Canada, 701-240-9411

[email protected]