Microneedle Template
Transcript of Microneedle Template
Manufactured by: Micropoint Technologies Pte Ltd
3, Soon Lee St., #04-37 Pioneer Junction, Singapore 627606 [email protected]
Micropoint Technologies Pte Ltd 3, Soon Lee St., #04-37 Pioneer Junction, Singapore 627606 Tel: +65 6262 4250 Email: [email protected]
Microneedle Template
Figure A Diagram A
Our disruptive technology MPatchTM Microneedle Templates (Figure A) incorporates cutting-
edge microneedle technology for moulding top-quality dissolvable microneedles. Based on our
proprietary fabrication technology, a stainless steel master mould is machined from which silicone
templates are moulded for making dissolvable microneedle patches. These silicone templates do
not degrade after repeated use. The dissolvable microneedles made from these templates have
sharp tips and well-defined edges.
Diagram A shows the parts of a silicone template. A: microneedle height; B: microneedle base;
C: microneedle pitch, which refers to the tip to tip distance; D: patch size; E: gap, it can be
calculated using following formula: E = microneedle pitch – microneedle base; F: length of last
microneedle cavity to the edge of patch, it can be calculated using following formula:
F = (patch size – [(n - 1) x pitch]) / 2, where n = number of microneedles in one array.
MPatchTM Microneedle Templates are
exclusively made for producing dissolvable
microneedle patches with excellent quality
and repeatability. These templates are made
of silicone rubber which is heat and chemical
resistant, and extremely durable.
Instructions for Use Ensure that the
MPatchTM Microneedle Templates are clean
by washing with mild soap and letting them
air dry completely. Next, pipette a small
quantity (50µl – 100µl) of the drug mixture
onto the microneedle catchment. Subject the
templates to centrifugal force for >60
seconds to ensure that all microneedle
cavities are completely filled-up. Then, dry
the patches (30% - 45% RH) for 4 – 48 hours
depending on the material used. Lastly, use
an adhesive tape to vertically de-mould the
formed microneedle patch from the
templates.
Product Specifications Characteristic Specification
Dimensions 19mm (Dia) x 4mm (H)
Material RTV Silicone (PDMS)
Array Size 6x6, 10x10, 15x15, etc.
Sterilization Autoclave (Optional)
Microneedle Dimensions
< 1,000µm Height (A) 100 – 250µm Base (B); 500 – 1500µm Pitch (C); 8x8/10x10mm2 Patch (D)
No. of Use Repeated Use
Operating Temp. -25 – 200 OC
F
D
B
C
E
A
Manufactured by: Micropoint Technologies Pte Ltd
3, Soon Lee St., #04-37 Pioneer Junction, Singapore 627606.
Micropoint Technologies Pte Ltd 3, Soon Lee St., #04-37 Pioneer Junction, Singapore 627606 Tel: +65 6262 4250 Email: [email protected]
Mini Applicator
Our disruptive technology MPatchTM Mini Applicator incorporates cutting-edge microneedle technology
for effectively applying microneedle patches on the skin (5mm – 15mm in diameter). This includes
stainless steel, plastic and dissolvable microneedle patches. Our applicators are engineered to provide the
required speed and force so that the micronneedles can penetrate the skin at 100% penetration rate.
MPatchTM Mini Applicator is used to apply
microneedle patches on the skin effectively
for drug delivery or cosmetic purposes.
Special Features MPatchM Mini Applicator
is specially engineered to apply microneedle
patches effectively by ensuring 100%
penetration rate. The penetration speed and
force is optimized to provide repeatable and
reproducible results.
Instructions for Use Affix a microneedle
patch on to the sample seat and cock the
applicator. Place the transparent cap over a
targeted skin site and apply mild pressure to
tension the skin. Activate the applicator by
pressing the trigger button. Hold the device
in place for at least 10 seconds or longer to
ensure that the microneedles are completely
inserted into the skin. This holding time is
crucial for the microneedle to dissolve in the
skin (if the microneedles are dissolvable).
Product Specifications
Characteristic Specification
Dimensions 20mm Dia. X 70mm L
Application Speed ~2.0 m/s
Impact Strength: Normal/ Enhanced/ High
Application Force ~1.6 N (Normal Strength)
Operations Mode Spring operated
Maximum Patch 15mm Dia.
No. of Use Repeated Use (Personal)
Manufactured by: Micropoint Technologies Pte Ltd
3, Soon Lee St., #04-37 Pioneer Junction, Singapore 627606.
Micropoint Technologies Pte Ltd 3, Soon Lee St., #04-37 Pioneer Junction, Singapore 627606 Tel: +65 6262 4250 Email: [email protected]
Casing and
Casing Insert
Our MPatchTM casing and MPatchTM casing insert are specially designed for the installation of
microneedle patches onto the MPatchTM Mini Applicator. They are also designed to provide protection
to the microneedle and aid in the installation of microneedle patches onto the applicator.
MPatchTM casing and MPatchTM casing
insert are used to install microneedle patches
onto the applicator without causing damage
to the microneedle patch.
Special Features MPatchTM casing and
MPatchTM casing insert are specially
designed to aid in the installation of
microneedle patch onto the MPatchTM Mini
Applicator. They are also designed to
provide protection and storage to
microneedle patch and reduce the risk of
damaging microneedle patch during
installation.
Instructions for Use Remove the liner of
medical grade adhesive on the casing insert.
Affix a microneedle patch on the casing
insert with medical grade adhesive. Store
casing insert with microneedle patch in a
casing. Cock the applicator with casing
loaded with microneedle patch. The
applicator is now ready for microneedle
application on targeted skin.
Product Specifications
Casing
Characteristic Specification
Material PC+ABS
Dimensions 16mm Dia. X 32mm H
Maximum Patch 10mm Dia.
No. of Use Repeated Use (Personal)
Casing Insert
Characteristic Specification
Material PC+ABS
Dimensions 16mm Dia. X 30mm H
Maximum Patch 10mm Dia.
No. of Use Repeated Use (Personal)
DATA SHEET LIQUID DISPENSING
9-POINT LIQUID DISPENSING HUB (METAL)
A 3x3 stainless steel hollow microneedle hub
Features:
Made from stainless steel needles
Tips are strong enough for repeated
skin penetrations
Sufficiently Sharp tips (<1 um)
Contains a luer-slip female for
connecting to a typical syringe
Potential Applications:
Industrial multiple-point dispensing:
o Glues, sealants, reagents etc.
Instructions for Use:
Load liquid to be dispensed in a
syringe barrel.
Connect the loaded syringe to the 9-
Point Liquid Dispensing Hub via the
luer-ship female connector.
Dispense liquid by pushing the
plunger.
Discard the used device into a
sharps collector.
3x3 Stainless Steel Hollow Microneedle Hub (Close-Up)
Physical Specifications
No Parameter Unit Value
1 Needle Height um 1,000 – 4,000
2 Needle Tip Size um < 1.0
3 Needle O.D. um 250
4 Inner Diameter um 150
5 Needle Pitch um 3,500
6 Needle Array Size - 5 or 9 (3x3)
Manufactured by Micropoint Technologies Pte Ltd 3, Soon Lee St., #04-37 Pioneer Junction, Singapore 627606. Email Address: [email protected]
No. Part No. Product Code Part Name Material Patch SizeArray Size
Needle Height
Needle Base
Needle Pitch
Price US$/10pcs
1 ST-01 ST-10x10-H300B100P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 300 100 500 $525.002 ST-02 ST-10x10-H400B150P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 400 150 500 $525.003 ST-03 ST-10x10-H500B150P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 500 150 500 $525.004 ST-04 ST-10x10-H500B200P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 500 200 500 $525.005 ST-05 ST-10x10-H600B200P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 600 200 500 $525.006 ST-06 ST-15x15-H600B200P500 Silicone Template PDMS 8 mm x 8 mm 15 x 15 600 200 500 $525.007 ST-07 ST-10x10-H700B200P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 700 200 500 $630.008 ST-08 ST-10x10-H800B200P500 Silicone Template PDMS 8 mm x 8 mm 10 x 10 800 200 500 $630.009 ST-09 ST-6x6-H800B250P500 Silicone Template PDMS 10 mm x 10 mm 6 x 6 800 250 500 $630.00
10 ST-10 ST-6x6-H1000B250P1000 Silicone Template PDMS 10 mm x 10 mm 6 x 6 1000 250 1000 $787.5011 ST-11 ST-6x6-H1000B250P1500 Silicone Template PDMS 10 mm x 10 mm 6 x 6 1000 250 1500 $787.5012 ST-12 ST-15x15-H500B200P1500 Silicone Template PDMS 30 mm x 30 mm 15 x 15 500 200 1500 $420.00/4pcs13 ST-13 ST-25x90-H300B200P500 Silicone Template PDMS 34 mm x 67 mm 25 x 90 300 200 500 $630/4pcs14 ST-14 ST-60x60-H250B100P850 Silicone Template PDMS 70 mm x 70 mm 60 x 60 250 100 850 $600/2pcs
No. Part No. Product Code Part Name MaterialPatch Size
Array Size
Needle Height
Needle Base
Needle Pitch
Price US$/pc
1 DMNA-01 DMNA-10x10-H300B100P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 300 100 500 $52.502 DMNA-02 DMNA-10x10-H400B150P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 400 150 500 $52.503 DMNA-03 DMNA-10x10-H500B150P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 500 150 500 $52.504 DMNA-04 DMNA-10x10-H500B200P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 500 200 500 $52.505 DMNA-05 DMNA-10x10-H600B200P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 600 200 500 $52.506 DMNA-06 DMNA-15x15-H600B200P500 Dissolving Microneedles HA 8 mm x 8 mm 15 x 15 600 200 500 $52.507 DMNA-07 DMNA-10x10-H700B200P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 700 200 500 $63.008 DMNA-08 DMNA-10x10-H800B200P500 Dissolving Microneedles HA 8 mm x 8 mm 10 x 10 800 200 500 $78.759 DMNA-09 DMNA-6x6-H800B250P500 Dissolving Microneedles HA 10 mm x 10 mm 6 x 6 800 250 500 $78.75
10 DMNA-10 DMNA-6x6-H1000B250P1000 Dissolving Microneedles HA 10 mm x 10 mm 6 x 6 1000 250 1000 $78.7511 DMNA-11 DMNA-6x6-H1000B250P1500 Dissolving Microneedles HA 10 mm x 10 mm 6 x 6 1000 250 1500 $78.7512 DMNA-12 DMNA-15x15-H500B200P1500 Dissolving Microneedles HA 30 mm x 30 mm 15 x 15 500 200 1500 $105.0013 DMNA-13 DMNA-25x90-H300B200P500 Dissolving Microneedles HA 34 mm x 67 mm 25 x 90 300 200 500 $157.5014 DMNA-14 DMNA-60x60-H250B100P850 Dissolving Microneedles HA 70 mm x 70 mm 60 x 60 250 100 850 $200
No. Part No. Part Name Material Patch Size Array Size Price US$AC-01 SA-01 Spring Applicator PC + ABS N/A N/A $126.00AC-02 CS-01 Casing PC + ABS 8mm x 8mm 10 x 10 $10.50AC-03 CI-01 Casing Insert PC + ABS 8mm x 8mm 10 x 10 $5.25