Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson...

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Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning
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Page 1: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Metabolism

Transformations and Interactions

Copyright 2005 Wadsworth Group, a division of Thomson LearningCopyright 2005 Wadsworth Group, a division of Thomson Learning

Page 2: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

What happens to all these nutrients?

• Your body cells derive two things from your food– Energy

• To help you move, think, breath etc

– Nutrients • Nutrients to grow (in children), to replace broken

down cells, to repair etc

Page 3: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Metabolism• Photosynthesis

• Fuel

• Metabolism

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Page 4: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Photosynthesis: Light energy is converted by plants to chemical energy

Respiration: Chemical energy stored in plants is converted by animals into new forms of chemical energy, mechanical energy, electrical energy and heat energy

• Metabolism = Anabolism + Catabolism

Page 5: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Breakdown/ HydrolysisProteins to Amino Acids, Starch to Glucose

Synthesis/CondensationAmino Acids to Proteins, Glucose to Starch

Yin & Yang of Metabolism

Metabolism = Anabolism + Catabolism

Page 6: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Chemical Reactions

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Page 7: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Adenosine Triphosphate

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Page 8: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Chemical Reactions• Coupled reactions

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Page 9: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

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A Typical Cell

Page 10: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Chemical Reactions• Helpers in reactions

– Enzymes•Cofactors

–Coenzymes

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Page 11: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Nutrients for Energy

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Page 12: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Nutrients for Energy• Glycolysis

• Pyruvate acetyl CoA

• TCA cycle

• Electron transport chain

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Page 13: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Example of Redox Equations

http://faculty.evansville.edu/md7/bact02/metabolism%20copy/metabolism_files/metabolism.ppt#17

Page 14: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Examples

• ATP ADP + P – Oxidation, release energy

• ADP + P ATP– Reduction, stores energy

• NAD + H NADH

• FAD + H2 FADH2

Page 15: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Copyright 2005 Wadsworth Group, a division of Thomson LearningCopyright 2005 Wadsworth Group, a division of Thomson Learning

Glycolysis: Glucose-to-Pyruvate

Page 16: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Glucose• The fate of pyruvate

– Anaerobic vs. aerobic pathways

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Page 17: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Glucose• The fate of pyruvate

– Anaerobic•Pyruvate-to-lactic acid

–Cori cycle

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Page 18: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Copyright 2005 Wadsworth Group, a division of Thomson LearningCopyright 2005 Wadsworth Group, a division of Thomson Learning

Pyruvate-to-Lactic Acid (Anaerobic)

Page 19: Metabolism Transformations and Interactions Copyright 2005 Wadsworth Group, a division of Thomson Learning.

Glucose• The fate of pyruvate

– Aerobic•Pyruvate-to-acetyl CoA

Copyright 2005 Wadsworth Group, a division of Thomson LearningCopyright 2005 Wadsworth Group, a division of Thomson Learning