Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd...
Transcript of Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd...
![Page 1: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/1.jpg)
Breeding your cows for genetic gain
Max Tweedie, B+LNZ Genetics
![Page 2: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/2.jpg)
Genetic improvement
Genetic improvement should be the key objective for a stud breeder.
⁃ Occurs when the sire team you select are of higher merit than the cows in your herd and ultimately breed calves that are superior to their parents
• Genetic change vs genetic improvement
![Page 3: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/3.jpg)
Raised on the exact same diet, for the same length of time, under the same conditions
![Page 4: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/4.jpg)
Factors: Heritability (h2)How much of what you see is genetic. Or… how much a calf is like its parents
• If its not heritable then you cant select
• Expressed 0 to 100% or 0 to 1
![Page 5: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/5.jpg)
Some of the questions you face
1. How many heifers should be kept for replacements?
2. How many sires should I use? And which sires?
3. Should I use a proven older sire or a promising young sire?
4. Should I use or buy in new bloodlines?
![Page 6: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/6.jpg)
PHENOTYPE = GENOTYPE + ENVIRONMENT
![Page 7: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/7.jpg)
The bell curve
Merit
Number of animals
![Page 8: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/8.jpg)
The bell curve
Merit
Number of animals
Average Top 5%Bottom 5%
![Page 9: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/9.jpg)
The bell curve
Merit
Number of animals
![Page 10: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/10.jpg)
The bell curve
Merit
Number of animals
![Page 11: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/11.jpg)
The Breeders Equation
Intensity x Accuracy x Differential
Generation Interval
Response =
![Page 12: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/12.jpg)
Selection intensity
How good the parents are. So… select the best parents
Intensity x Accuracy x Variation
Generation Interval
Response =
![Page 13: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/13.jpg)
Selection accuracy Difference between estimated and true genetic merit
⁃ the Better the info contributing to the EBV the better the accuracy⁃ Can still have gain with low accuracy⁃ Trade offs. Should I use a proven bull or a promising young
sire?Intensity x Accuracy x Variation
Generation Interval
Response =
![Page 14: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/14.jpg)
Variation
Intensity x Accuracy x Variation
Generation Interval
Response =
Narrow -selection leads to little difference in the mean
Wide -selection leads to a larger difference in the mean
Extreme ends of the scale are inbreeding depression and Hybrid Vigour• Use more sires. Product consistency trade off
![Page 15: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/15.jpg)
Generation interval Average age of your herdYearling bulls to yearling heifers?
Intensity x Accuracy x Variation
Generation Interval
Response =
![Page 16: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/16.jpg)
Antagonisms
• Intensity and variation (the best parents are often related)
• Accuracy and generation interval (young bulls-not enough info)⁃ Genomics
![Page 17: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/17.jpg)
Balance the breeders equation
If the relative factors of genetic change can be achieved in balance then there is no end to the potential improvement within a
programme
van der Werf et al. 2011
![Page 18: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/18.jpg)
Ramping up gain: Tools and Methods
Get a breeding objective⁃ This gives you the goal
• Record what's important to that objective
• If you are selecting on many traits you wont go as fast⁃ Index selection is a good idea for balance
![Page 19: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/19.jpg)
Ramping up gain: Tools and Methods
Spread the good genes
⁃ ET (Intensity)⁃ A.I (Intensity)
* Trade off is price
![Page 20: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/20.jpg)
Ramping up gain: Tools and MethodsMake sure your EBVs are solid (Accuracy)
⁃ DNA parentage⁃ Use your EID tags- electronic capture⁃ Get a herd recording software⁃ Improve you herd star rating⁃ Genomics- if this is available to you
![Page 21: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/21.jpg)
Gold standard vs bronze recording
![Page 22: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/22.jpg)
Ramping up gain: Tools and Methods
Choose good bulls (Intensity)
⁃ They determine 80% of the genes in your herd⁃ Use more sires
![Page 23: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/23.jpg)
Ramping up gain: Tools and Methods
Heifer selection ⁃ Mate as many as you can and mate them young⁃ Be objective about their place in the herd⁃ Genomics
Cow selection (Culling)⁃ Less effective as sire but must chip away⁃ Represents 20% of the potential gain in your herd
![Page 24: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/24.jpg)
Ramping up gain: Tools and Methods
Optimised mating software (Variation + Balance)
⁃ Paint by numbers mating for genetic gain
⁃ No inbreeding
⁃ Best parent to parent combo in each mating
![Page 25: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/25.jpg)
Summary• Get a breeding objective
• Balance the Breeders Equation
• Use the tools and methods - key being performance recording
Intensity x Accuracy x Variation
Generation Interval
![Page 26: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/26.jpg)
‘There is no end to the improvement of anything biological, it may slow down but it will go on’
Gavin Faloon, 2014
![Page 27: Max Tweedie, B+LNZ Genetics · Factors: Heritability (h2) ... ⁃DNA parentage ... ⁃Get a herd recording software ⁃Improve you herd star rating ⁃Genomics-if this is available](https://reader031.fdocuments.in/reader031/viewer/2022030707/5af461b97f8b9a92718d78b9/html5/thumbnails/27.jpg)
Thank you.