mannosyltransferase:6.90E-212 C:Golgi apparatus (ISS) - A... · transport (ISS) | P:vesicle-...

ORF Contig Exons Introns Chrom Sugg.Name Pub.Name Synonym Allele Product Notes EC DBXREF PFAM COGsMIPS Remove GOterm-C GOterm-F GOterm-P orf19.10 Contig19-10011 complement(3769..5316) RX ALK8 orf19.7683 | IPF27231.1 | Contig20011:complement(5305..3758) cytochrome p450 gene family 1.14.14.1 | 1.6.2.4 gi|3395458|emb|CAA75058.1| alk8 [Candida albicans] | CandidaDB:CA0651 | CYGD:CA0651 | IPF:11568.1 PF00067:p450; Cytochrome P450:1.40E-40 COG2124 Cytochrome P450 8e-99 C:cellular_component unknown (ND) F:cytochrome P450 (ISS) | F:enzyme (ISS) orf19.100 Contig19-10035 complement(33781..34833) 6O LIP11 orf19.7747 | IPF10462.3 | Contig20035:complement(34456..33401) triacylglycerol lipase 3.1.1.3 CandidaDB:CA0093 | CYGD:CA0093 | IPF:29954.1 PF01764:Lipase_3; Lipase (class 3):1.10E-09 orf19.1002 Contig19-10081 complement(32951..34843) 1E or 1L orf19.8618 | IPF26289.1 | Contig20081:complement(34863..32971) hypothetical protein CandidaDB:CA3517 | CYGD:CA3517 | IPF:15371.2 PF00560:LRR; Leucine Rich Repeat:1.00E-02 C:plasma membrane (ISS) F:adenylate cyclase (ISS) P:G-protein signaling, coupled to cAMP nucleotide second messenger (ISS) | P:RAS protein signal transduction (ISS) | P:meiosis (ISS) | P:regulation of cell cycle (ISS) orf19.1003 Contig19-10081 complement(35841..36371) 1E or 1L orf19.8619 | IPF19532.1 | Contig20081:complement(36703..35861) hypothetical protein IPF:18326.1 PF00560:LRR; Leucine Rich Repeat:9.30E-01 C:plasma membrane (ISS) F:adenylate cyclase (ISS) P:G-protein signaling, coupled to cAMP nucleotide second messenger (ISS) | P:RAS protein signal transduction (ISS) | P:meiosis (ISS) | P:regulation of cell cycle (ISS) orf19.1004 Contig19-10081 38290..>38910 1E or 1L orf19.8620 | IPF26296.1 | Contig20081:38310..38930 hypothetical protein truncated protein IPF:15152.3 orf19.1005 Contig19-1623 complement(1016..2824) LRR leucine rich repeats gene family IPF:15368.2 PF00560:LRR; Leucine Rich Repeat:1.80E-03 orf19.1006 Contig19-10083 complement(

mannosyltransferase:6.90E-212 C:Golgi apparatus (ISS) F:alpha-1,2- mannosyltransferase (ISS) | F:alpha-1,2- mannosyltransferase (ISS) P:N-glycan processing (ISS) | P:O-linked glycosylation (ISS) | P:cell wall mannoprotein biosynthesis (ISS) orf19.1011 Contig19-10083 complement(4999..6981) RK MNN2 orf19.8625 | IPF26282.1 | Contig20083:complement(6999..4984) alpha-1,2-mannosyltransferase CandidaDB:CA0951 | CYGD:CA0951 | IPF:3740.1 C:Golgi apparatus (ISS) F:alpha-1,2- mannosyltransferase (ISS) | F:alpha-1,2- mannosyltransferase (ISS) P:protein amino acid glycosylation (ISS) orf19.1012 Contig19-10083 8272..8733 RK APS1 orf19.8626 | IPF26284.1 | Contig20083:8257..8718 AP-1 clathrin associated protein complex subunit CandidaDB:CA0950 | CYGD:CA0950 | IPF:3737.2 PF01217:Clat_adaptor_s; Clathrin adaptor complex small chain:2.90E-66 C:AP-1 adaptor complex (ISS) | C:AP-1 adaptor complex (ISS) F:clathrin binding (ISS) | F:clathrin binding (ISS) P:vesicle-mediated transport (ISS) | P:vesicle- mediated transport (ISS) orf19.1013 Contig19-10083 complement(11735..12046) RK orf19.8627 | IPF26286.1 | Contig20083:complement(12100..11720) hypothetical protein IPF:29603.1 orf19.1014 Contig19-1637 363..1058 probable 26S proteasome regulatory subunit overlap with orf19.2301 IPF:19212.2 orf19.1016 Contig19-1637 complement(1088..1393) URM12 ubiquitin-like protein Overlap with orf19.2299 IPF:19211.1 C:cellular_component unknown (ND) F:molecular_function unknown (ND) P:protein modification (ISS) orf19.1017 Contig19-1637 complement(1623..3155) PEP38 vacuolar membrane protein gene family CandidaDB:CA0134 | CYGD:CA0134 | IPF:17921.2 C:extrinsic vacuolar membrane protein (ISS) | C:vacuolar membrane (sensu Fungi) (ISS) F:protein binding (ISS) | F:protein binding (ISS) P:Golgi to endosome transport ((ISS)) | P:homotypic vacuole fusion (non- autophagic) (ISS) | P:late endosome to vacuole transport ((ISS)) | P:non-selective vesicle docking (ISS) orf19.1018 Contig19-1637 complement(3855..>4541) TEL12 involved in controlling telomere length | ataxia telangiectasia (ATM) gene homolog Overlap with orf19.5580 | truncated protein IPF:17919.2 PF00454:PI3_PI4_kinase; Phosphatidylinositol 3- and 4-kinase:4.20E-13 C:cellular_component unknown (ND) F:inositol/phosphatidylinositol kinase (ISS) P:response to DNA damage (ISS) | P:telomerase-dependent telomere maintenance (ISS) orf19.1019 Contig19-1638 complement(442..2874) 7 VPS18 VPS18 vacuolar membrane protein gene family CandidaDB:CA0135 | CYGD:CA0135 | IPF:11032.1 C:extrinsic vacuolar membrane protein (ISS) | C:vacuolar membrane (sensu Fungi) (ISS) F:protein binding (ISS) | F:protein binding (ISS) P:Golgi to endosome transport ((ISS)) | P:homotypic vacuole fusion (non- autophagic) (ISS) | P:late endosome to vacuole transport ((ISS)) | P:non-selective vesicle docking (ISS) orf19.102 Contig19-10035 complement(36568..37818) 6O orf19.7749 | IPF17548.2 | Contig20035:complement(37543..36188) hypothetical protein CandidaDB:CA1151 | CYGD:CA1151 | IPF:10459.1 C:cohesin (ISS) F:molecular_function unknown (ND) P:mitotic sister chromatid cohesion (ISS) orf19.1020 Contig19-1638 complement(3738..4139) 7 hypothetical protein IPF:11030.2

orf19.1021 Contig19-1648 1..612 LRR leucine rich repeat gene family | sequencing error? CandidaDB:CA0141 | CYGD:CA0141 | IPF:17520.1 orf19.1022 Contig19-1648 727..1713 LRR leucine rich repeat gene family IPF:17517.1 PF00560:LRR; Leucine Rich Repeat:3.20E-03 orf19.1023 Contig19-1648 complement(2746..3180) hypothetical protein IPF:17516.2 orf19.1024 Contig19-1648 complement(3803..4246) hypothetical protein IPF:19203.2 orf19.1026 Contig19-10087 1489..2472 1S CSL4 orf19.8628 | IPF15779.2 | Contig20087:1440..2423 exosome 3'->5exonuclease | involved in kinetochore-related function CandidaDB:CA0142 | CYGD:CA0142 | IPF:17757.1 COG1096 Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) 1e-120 C:cytoplasmic exosome (RNase complex) (ISS) | C:nuclear exosome (RNase complex) (ISS) F:3'-5' exoribonuclease (ISS) P:35S primary transcript processing (ISS) | P:mRNA catabolism (ISS) orf19.1027 Contig19-10087 complement(2638..3747) 1S PDR16 orf19.8629 | IPF15777.2 | Contig20087:complement(3700..2591) phosphatidylinositol transfer protein | drug resistance gene family IPF:19201.1 PF00650:CRAL_TRIO; CRAL/TRIO domain:8.80E-54 C:cytoplasm (ISS) F:molecular_function unknown (ND) P:drug susceptibility/resistance (ISS) | P:sterol biosynthesis (ISS) orf19.1028 Contig19-10087 6119..7297 1S ELA1 orf19.8630 | IPF19583.2 | Contig20087:6102..7280 transcriptional elongation factor CandidaDB:CA1631 | CYGD:CA1631 | IPF:19582.1 C:transcription elongation factor complex (ISS) F:transcription elongation factor (ISS) P:RNA elongation from Pol II promoter (ISS) orf19.1029 Contig19-10087 complement(7389..8321) 1S RPP1 orf19.8631 | IPF26259.1 | Contig20087:complement(8572..7448) nuclear ribonuclease P subunit (RNase P)| required for processing of tRNA and 35S rRNA CandidaDB:CA1630 | CYGD:CA1630 | IPF:14315.2 PF01876:RNase_P_p30; RNase P subunit p30:7.30E-28 COG1603 ribonuclease P subunit Rpp30 1e-99 C:ribonuclease P complex (ISS) | C:ribonuclease mitochondrial RNA processing complex (ISS) F:ribonuclease MRP (ISS) | F:ribonuclease P (ISS) P:rRNA processing (ISS) | P:tRNA processing (ISS) orf19.103 Contig19-10035 38218..38595 6O conserved hypothetical protein CandidaDB:CA1152 | CYGD:CA1152 | IPF:10457.3 orf19.1030 Contig19-10087 8655..9935 1S FPR3 NPI46 orf19.8632 | IPF26252.1 | Contig20087:8640..9926 peptidyl-prolyl cis-trans isomerases (PPIase)| FK506-rapamycin binding protein 5.2.1.8 CandidaDB:CA1629 | CYGD:CA1629 | IPF:14314.2 PF00254:FKBP; FKBP-type peptidyl-prolyl cis- trans isomerase:1.50E-36 COG1047 FKBP-type peptidyl-prolyl cis-trans isomerases 2 6e-23\nCOG0545 FKBP-type peptidyl-prolyl cis- trans isomerases 1 2e-39\nCOG0544 FKBP-type peptidyl- prolyl cis-trans isomerase (trigger factor) 1e-34 C:nucleolus (NR) F:peptidyl-prolyl cis-trans isomerase (NR) P:biological_process unknown (NR) orf19.1031 Contig19-10087 11896..15117 1S HMG1 orf19.8633 | IPF26280.1 | Contig20087:11887..15108 3-hydroxy-3-methyl-glutaryl coenzyme A reductase (HMG-CoA) 1.1.1.88 CandidaDB:CA1628 | CYGD:CA1628 | IPF:19736.1 PF00368:HMG-CoA_red; Hydroxymethylglutaryl- coenzyme A reductase:8.10E-282 COG1257 Hydroxymethylglutaryl-CoA reductase 0.0 C:endoplasmic reticulum membrane (ISS) | C:mitochondrial matrix

(ISS) | C:nuclear membrane (ISS) F:hydroxymethylglutaryl-CoA reductase (NADPH) (ISS) P:ergosterol biosynthesis (ISS) orf19.1032 Contig19-10087 complement(15338..>17062) 1S SKO1 ACR1 orf19.8634 | IPF26249.1 | Contig20087:complement(17053..15329) CREB like trancsriptional repressor | bZIP protein CandidaDB:CA1627 | CYGD:CA1627 | IPF:6153.2 PF00170:bZIP; bZIP transcription factor:1.10E- 05 P:transcription (IEA) orf19.1033 Contig19-10087 18606..20393 1S STR2 orf19.8635 | IPF26248.1 | Contig20087:18597..20384 cystathionine gamma-synthase | Sulfur TRansfer 2.5.1.48 CandidaDB:CA1626 | CYGD:CA1626 | IPF:6155.2 PF01053:Cys_Met_Meta_PP; Cys/Met metabolism PLP-dependent enzyme:5.30E-12 COG2873 O-acetylhomoserine sulfhydrylase 3e- 80\nCOG0626 Cystathionine beta-lyases/cystathionine gamma- synthases 1e-136 C:cellular_component unknown (ND) F:cystathionine- gamma-lyase (ISS) P:sulfur metabolism (ISS) orf19.1034 Contig19-10087 complement(20468..21019) 1S ATM2 orf19.8636 | IPF18786.2 | Contig20087:complement(21138..20461) putative steroid binding CandidaDB:CA1625 | CYGD:CA1625 | IPF:6156.1 PF00173:heme_1; Heme/Steroid binding domain:8.00E-05 orf19.1035 Contig19-10087 complement(21525..24368) 1S WAR1 orf19.8637 | IPF6159.2 | Contig20087:complement(24360..21517) transcription factor activity CandidaDB:CA1038 | CYGD:CA1038 | IPF:17784.3 PF00172:Zn_clus; Fungal Zn(2)-Cys(6) binuclear cluster domain:2.40E-04 orf19.1036 Contig19-10087 26898..28745 1S MNS1 orf19.8638 | IPF6163.1 | Contig20087:27046..28743 mannosyl- oligosaccharide 1,2-alpha-mannosidase 3.2.1.24 | 3.2.1.113 CandidaDB:CA1037 | CYGD:CA1037 | IPF:29592.1 PF01532:Glyco_hydro_47; Glycosyl hydrolase family 47:3.10E-174 C:endoplasmic reticulum (ISS) F:mannosyl- oligosaccharide 1,2-alpha-mannosidase (ISS) | F:mannosyl- oligosaccharide 1,2-alpha-mannosidase (IEA) P:N-linked glycosylation (ISS) orf19.1037 Contig19-10087 29703..30434 1S orf19.8639 | IPF26266.1 | Contig20087:29701..30432 hypothetical protein CandidaDB:CA1036 | CYGD:CA1036 | IPF:19718.1 orf19.1038 Contig19-10087 30346..31476 1S orf19.8640 | IPF26258.1 | Contig20087:30374..31474 hypothetical protein CandidaDB:CA1035 | CYGD:CA1035 | IPF:13751.2 orf19.1039 Contig19-10087 complement(join(31624..32727,32812..32814)) complement(32728..32811) 1S BET4 BET4 orf19.8641 | IPF17890.1 | Contig20087:complement(32725..31622) geranylgeranyltransferase type II alpha subunit 2.5.1.29 gi|4049599|dbj|BAA35192.1| alpha subunit of geranylgeranyl transferaes type 2 [Candida albicans] | CandidaDB:CA1034 | CYGD:CA1034 | IPF:29595.1 PF01239:PPTA; Protein prenyltransferase alpha subunit repeat:3.00E-09 C:RAB-protein geranylgeranyltransferase complex (ISS) F:RAB-protein geranylgeranyltransferase (ISS) P:protein amino acid geranylgeranylation (ISS) orf19.104 Contig19-10035 38794..39648 6O orf19.7750 | IPF17213.3 | Contig20035:37805..39262 hypothetical protein CandidaDB:CA1153 | CYGD:CA1153 | IPF:10455.3 orf19.1040 Contig19-10087 33018..33662 1S MAD2 orf19.8642 | IPF17891.2 | Contig20087:33026..33664 spindle checkpoint complex subunit IPF:17882.3 PF02301:HORMA; HORMA domain:1.20E-40 C:nucleus (ISS) F:molecular_function unknown (ISS) P:mitotic spindle checkpoint (ISS)

orf19.1041 Contig19-10087 complement(33673..35160) 1S CTK2 orf19.8643 | IPF26251.1 | Contig20087:complement(35171..33675) RNA polymerase II C-terminal domain kinase beta subunit CandidaDB:CA0918 | CYGD:CA0918 | IPF:17881.2 PF00134:cyclin; Cyclin, N-terminal domain:1.40E-04 C:nucleus (ISS) F:cyclin-dependent protein kinase, regulator (ISS) P:protein amino acid phosphorylation (ISS) | P:regulation of transcription from Pol II promoter (ISS) orf19.1042 Contig19-10087 complement(35388..36236) 1S POR1 OMP2 orf19.8644 | IPF26262.1 | Contig20087:complement(36238..35390) porin|voltage-dependent anion channel(VDAC) CandidaDB:CA0919 | CYGD:CA0919 | IPF:12994.2 PF01459:Euk_porin; Eukaryotic porin:1.20E-117 C:mitochondrial outer membrane (ISS) F:voltage- dependent ion-selective channel (ISS) P:aerobic respiration (ISS) | P:ion transport (ISS) | P:mitochondrion organization and biogenesis (ISS) orf19.1043 Contig19-10087 37802..38719 1S VPS66 orf19.8645 | IPF26261.1 | Contig20087:37811..38728 vacuolar Protein Sorting CandidaDB:CA0921 | CYGD:CA0921 | IPF:12992.2 C:cytoplasm (ISS) F:molecular_function unknown (ND) P:protein-vacuolar targeting (ISS) orf19.1045 Contig19-10087 complement(38781..39842) 1S orf19.8647 | IPF26260.1 | Contig20087:complement(39860..38790) conserved RNA-binding protein | IST3-like CandidaDB:CA0922 | CYGD:CA0922 | IPF:12991.1 PF00076:rrm; RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain):1.50E-18 C:snRNP U2 (ISS) F:pre-mRNA splicing factor (ISS) P:spliceosome assembly (ISS) orf19.1047 Contig19-10087 39890..42439 1S ERB1 orf19.8649 | IPF26243.1 | Contig20087:39929..42448 maturation of the 25S and 5.8S ribosomal RNAs CandidaDB:CA0923 | CYGD:CA0923 | IPF:12987.2 PF00400:WD40; WD domain, G-beta repeat:9.40E- 37 orf19.1048 Contig19-10087 43147..44181 1S IFD1 orf19.8650 | IPF18856.2 | Contig20087:43153..44187 conserved aryl-alcohol dehydrogenase gene family 1.1.1.91 CandidaDB:CA0924 | CYGD:CA0924 | IPF:17049.2 PF00248:aldo_ket_red; Aldo/keto reductase family:1.00E-62 C:cellular_component unknown (ND) F:benzyl alcohol dehydrogenase (ISS) P:aldehyde metabolism (ISS) orf19.1049 Contig19-10087 complement(44270..44854) 1S orf19.8651 | IPF18855.2 | Contig20087:complement(44862..44278) 8-oxo-dGTPase CandidaDB:CA0925 | CYGD:CA0925 | IPF:17050.1 PF00293:NUDIX; NUDIX domain:9.80E-11 COG1051 ADP-ribose pyrophosphatase 4e- 25\nCOG0494 NTP pyrophosphohydrolases including oxidative damage repair enzymes 4e-21\nCOG2816 NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding 2e-22 orf19.105 Contig19-10035 40056..41132 6O MET22 3'(2')5'-bisphosphate nucleotidase , possibly involved in salt tolerance and methionine synthesis gene famliy 3.1.3.7 CandidaDB:CA1154 | CYGD:CA1154 | IPF:10454.1 PF00459:inositol_P; Inositol monophosphatase family:4.60E-59 C:cytoplasm (ISS) F:3'(2'),5'-bisphosphate nucleotidase (ISS) P:methionine biosynthesis (ISS) | P:sulfate assimilation (ISS) orf19.1050 Contig19-10087 complement(45190..46092) 1S orf19.8652 | IPF15638.2 | Contig20087:complement(46103..45192) hypothetical protein CandidaDB:CA0841 | CYGD:CA0841 | IPF:17051.3 orf19.1051 Contig19-10087 complement(46438..46833) 1S HTA2 H2A1 orf19.8653 | IPF26275.1 | Contig20087:complement(46844..46449)

histone 2A gene family IPF:15637.2 PF00125:histone; Core histone H2A/H2B/H3/H4:1.60E-52 C:nucleosome (ISS) F:DNA binding (ISS) P:chromatin assembly/disassembly (ISS) orf19.1052 Contig19-10087 47700..48092 1S HTB2 orf19.8654 | IPF26276.1 | Contig20087:47711..48103 histone 2B gene family IPF:15634.2 PF00125:histone; Core histone H2A/H2B/H3/H4:6.10E-51 C:nucleosome (ISS) | C:nucleosome (ISS) F:DNA binding (ISS) | F:DNA binding (ISS) P:chromatin assembly/disassembly (ISS) | P:chromatin assembly/disassembly (ISS) | P:chromatin assembly/disassembly (ISS) orf19.1053 Contig19-10087 complement(48361..49533) 1S BST1 orf19.8655 | IPF26257.1 | Contig20087:complement(49559..48372) negative regulator of COPII vesicle formation CandidaDB:CA0842 | CYGD:CA0842 | IPF:15633.2 C:endoplasmic reticulum (ISS) | C:integral membrane protein (ISS) F:molecular_function unknown (ND) P:ER- associated protein catabolism (ISS) | P:vesicle organization and biogenesis (ISS) orf19.1054 Contig19-10087 complement(50351..51160) 1S orf19.8656 | IPF18853.1 | Contig20087:complement(51174..50362) hypothetical protein CandidaDB:CA0843 | CYGD:CA0843 | IPF:16097.3 orf19.1055 Contig19-10087 complement(join(52162..53438,53549..53558)) complement(53439..53548) 1S CDC3 CDC3 orf19.8657 | IPF16098.2 | Contig20087:complement(53301..52165) septin | cell cycle | involved in proper bud growth Possible intron (size=110) gtatgtatat...tctaatatag gi|578116|emb|CAA81089.1| deduced CDC3 protein from Candida albicans | IPF:29594.1 PF00735:GTP_CDC; Cell division protein:3.80E- 178 C:prospore membrane (ISS) | C:septin ring (sensu Saccharomyces) (ISS) | C:shmoo (ISS) F:structural constituent of cytoskeleton (ISS) P:axial budding (ISS) | P:cell wall organization and biogenesis (ISS) | P:cytokines orf19.1057 Contig19-10087 complement(54507..55076) 1S orf19.8659 | IPF26268.1 | Contig20087:complement(55626..55057) conserved hypothetical protein CandidaDB:CA2864 | CYGD:CA2864 | IPF:17234.2 PF02464:CinA; Competence-damaged protein:1.70E-09 COG1546 Uncharacterized protein (competence- and mitomycin-induced) 2e-55 orf19.1058 Contig19-10087 join(55401..55867,56015..56381) 55868..56014 1S orf19.8660 | IPF26270.1 | Contig20087:55951..56421 RPN13-like conserved protein Possible intron (size=147) gtaagtatag...tattactaag CandidaDB:CA2863 | CYGD:CA2863 | IPF:20117.1 C:19S proteasome regulatory particle (ISS) F:molecular_function unknown (ND) P:proteolysis and peptidolysis (ISS) | P:proteolysis and peptidolysis (ISS) orf19.1059 Contig19-10087 complement(56705..57022) 1S HHF1 orf19.8661 | IPF26279.1 | Contig20087:complement(57572..57255) histone H4 gene family CandidaDB:CA2862 | CYGD:CA2862 | IPF:7050.1 PF00125:histone; Core histone H2A/H2B/H3/H4:5.50E-07 C:nucleosome (ISS) F:DNA binding (ISS) P:chromatin assembly/disassembly (ISS) orf19.1060 Contig19-10087 complement(57133..57642) 1S orf19.8662 | IPF26269.1 | Contig20087:complement(58267..57683) hypothetical protein IPF:19964.1 orf19.1061 Contig19-10087 57931..58341 1S HHT1 orf19.8663 | IPF26271.1 | Contig20087:58481..58891 histone H3 gene family CandidaDB:CA2861 | CYGD:CA2861 | IPF:7053.2 PF00125:histone; Core

histone H2A/H2B/H3/H4:8.60E-26 C:nucleosome (ISS) F:DNA binding (ISS) P:chromatin assembly/disassembly (ISS) orf19.1062 Contig19-10087 complement(58685..59920) 1S orf19.8664 | IPF26254.1 | Contig20087:complement(60470..59235) conserved hypothetical protein gene family CandidaDB:CA2860 | CYGD:CA2860 | IPF:7054.1 orf19.1063 Contig19-10087 complement(60316..61500) 1S FMP44 orf19.8665 | IPF26256.1 | Contig20087:complement(62050..60866) conserved hypothetical protein CandidaDB:CA2859 | CYGD:CA2859 | IPF:7056.2 P:biological_process unknown (IEA) orf19.1064 Contig19-10087 complement(61776..63791) 1S ACS2 orf19.8666 | IPF26246.1 | Contig20087:complement(64356..62326) acetyl-coenzyme A synthetase gene family 6.2.1.1 CandidaDB:CA2858 | CYGD:CA2858 | IPF:7057.2 PF00501:AMP-binding; AMP-binding enzyme:4.80E- 123 C:cytosol (ISS) F:acetate-CoA ligase (ISS) P:acetyl-CoA biosynthesis (ISS) orf19.1065 Contig19-10087 complement(66141..68078) 1S SSA2 orf19.8667 | IPF26247.1 | Contig20087:complement(68628..66691) chaperonin of the HSP70 family gene family CandidaDB:CA2857 | CYGD:CA2857 | IPF:7060.2 PF00012:HSP70; Hsp70 protein:0.00E+00 C:cytoplasm (ISS) F:chaperone (ISS) | F:heat shock protein (ISS) P:SRP-dependent, co-translational membrane targeting, translocation (ISS) | P:protein folding (ISS) | P:response to stress (ISS) | P:response to stress (ISS) orf19.1066 Contig19-10087 complement(68678..69442) 1S orf19.8668 | IPF26264.1 | Contig20087:complement(69992..69228) conserved hypothetical protein CandidaDB:CA2856 | CYGD:CA2856 | IPF:7062.2 orf19.1067 Contig19-10087 70860..71645 1S GPM2 orf19.8669 | IPF26265.1 | Contig20087:71410..72195 phosphoglycerate mutase gene family 5.4.2.1 CandidaDB:CA2855 | CYGD:CA2855 | IPF:7065.1 PF00300:PGAM; Phosphoglycerate mutase family:1.50E-68 C:cytosol (ISS) F:phosphoglycerate mutase (ISS) P:gluconeogenesis (ISS) | P:glycolysis (ISS) orf19.1069 Contig19-10087 73705..75315 1S RPN4 orf19.8671 | IPF26253.1 | Contig20087:74467..75861 Regulatory Particle Non-ATPase CandidaDB:CA2854 | CYGD:CA2854 | IPF:7070.2 PF00096:zf-C2H2; Zinc finger, C2H2 type:6.40E- 07 C:19S proteasome regulatory particle (ISS) | C:19S proteasome regulatory particle (ISS) F:proteasome endopeptidase (ISS) | F:proteasome endopeptidase (ISS) P:ubiquitin-dependent protein catabolism (ISS) | P:ubiquitin-dependent protein catabolism (ISS) orf19.107 Contig19-10035 complement(41188..43683) 6O DHR2 orf19.7754 | IPF27157.1 | Contig20035:complement(43299..40801) DEAH-box RNA helicase CandidaDB:CA1155 | CYGD:CA1155 | IPF:10452.3 PF00271:helicase_C; Helicase conserved C- terminal domain:4.80E-15 C:nucleolus (ISS) F:RNA helicase (ISS) P:ribosome biogenesis (ISS) | P:ribosome biogenesis (ISS) orf19.1070 Contig19-10087 complement(75754..76848) 1S orf19.8672 | IPF26255.1 | Contig20087:complement(77394..76300) conserved hypothetical protein CandidaDB:CA2853 | CYGD:CA2853 | IPF:17057.2 orf19.1071 Contig19-10087 complement(77317..78018) 1S orf19.8673 | IPF26263.1 | Contig20087:complement(78564..77863) hypothetical protein sequencing error? IPF:17059.3 orf19.1072 Contig19-1673 complement(319..633) hypothetical protein

orf19.1073 Contig19-1673 complement(2191..>3066) hypothetical protein truncated protein CandidaDB:CA0158 | CYGD:CA0158 | IPF:19178.2 orf19.1074 Contig19-10090

protein CandidaDB:CA0372 | CYGD:CA0372 | IPF:10062.2 PF02136:NTF2; Nuclear transport factor 2 (NTF2) domain:2.70E-05 orf19.1087 Contig19-10090 27159..29579 6C orf19.8688 | IPF19579.1 | Contig20090:27108..29540 hypothetical protein CandidaDB:CA0371 | CYGD:CA0371 | IPF:19578.1 orf19.1089 Contig19-10090 30120..30857 6C PEX11 orf19.8690 | IPF19049.2 | Contig20090:30096..30833 peroxisomal membrane protein CandidaDB:CA0310 | CYGD:CA0310 | IPF:29582.1 C:peroxisomal membrane (ISS) F:molecular_function unknown (ND) P:peroxisome organization and biogenesis (ISS) orf19.109 Contig19-10035 43905..45410 6O MSY1 orf19.7756 | IPF11923.1 | Contig20035:43520..45025 tyrosyl-tRNA synthetase 6.1.1.1 CandidaDB:CA1193 | CYGD:CA1193 | IPF:10449.3 PF00579:tRNA-synt_1b; tRNA synthetases class I (W and Y):6.60E-92 COG0180 Tryptophanyl-tRNA synthetase 3e- 66\nCOG0162 Tyrosyl-tRNA synthetase 1e-117 F:tyrosine-tRNA ligase (IEA) P:biological_process unknown (ND) orf19.1090 Contig19-10090 complement(31044..31391) 6C orf19.8691 | IPF26232.1 | Contig20090:complement(31367..31020) hypothetical protein IPF:16934.2 orf19.1091 Contig19-10090 31618..33690 6C NOP8 orf19.8692 | IPF26223.1 | Contig20090:31594..33666 nucleolar protein required for 60S ribosome biogenesis CandidaDB:CA0309 | CYGD:CA0309 | IPF:16935.2 C:nucleolus (ISS) F:RNA binding (ISS) P:rRNA processing (ISS) | P:ribosomal large subunit assembly and maintenance (ISS) orf19.1092 Contig19-10090 34034..35593 6C RHK1 orf19.8693 | IPF17442.2 | Contig20090:34010..35602 dol-p-man dependent alpha(1-3) mannosyltransferase CandidaDB:CA0308 | CYGD:CA0308 | IPF:29580.1 P:protein amino acid glycosylation (IEA) orf19.1093 Contig19-10090 complement(36230..38608) 6C orf19.8695 | IPF26221.1 | Contig20090:complement(38662..36209) hypothetical protein CandidaDB:CA1476 | CYGD:CA1476 | IPF:10214.2 orf19.1095 Contig19-10090 complement(41065..42216) 6C GLE2 orf19.8697 | IPF26226.1 | Contig20090:complement(42195..41044) nuclear pore protein CandidaDB:CA1475 | CYGD:CA1475 | IPF:10209.2 PF00400:WD40; WD domain, G-beta repeat:2.80E- 36 C:nuclear pore (ISS) F:structural molecule (ISS) P:NLS-bearing substrate-nucleus import (ISS) | P:mRNA- binding (hnRNP) protein-nucleus import (ISS) | P:mRNA- nucleus export (ISS) | P:nuclear membrane organization and biogenesis (ISS) | P:nuclear pore organization and biogenesis (ISS) | P:protein-nucleus export (ISS) | P:protein-nucleus import (ISS) | P:rRNA-nucleus export (ISS) | P:ribosomal protein-nucleus import (ISS) | P:snRNA- nucleus export (ISS) | P:snRNP protein-nucleus import (ISS) | P:tRNA-nucleus export (ISS) orf19.1096 Contig19-10090 42504..45143 6C GEF2 orf19.8698 | IPF26218.1 | Contig20090:42483..45122 chloride channel, possibly voltage gated CandidaDB:CA1474 | CYGD:CA1474 | IPF:10208.2 PF00654:voltage_CLC; Voltage gated chloride channel:3.30E-100 COG0038 Chloride channel protein EriC 1e-116 C:Golgi vesicle (ISS) F:voltage-gated chloride channel (ISS) P:cation homeostasis (ISS) orf19.1097 Contig19-10090 join(47877..>53144,55301) 6C ALS4 orf19.8700 | IPF26222.1 | Contig20090:53175..55280 | orf19.8699 | IPF26230.1 | Contig20090:47856..53126 misassembled agglutinin like protein truncated protein | gene family | sequencing error? | This sequence

contains about 48 copies of the tandem repeat sequence. ALS4 allele sizes in strain SC5314 are estimated by Southern blot to have 18 or 36 copies of the repeated sequence. The 3Æ end of the gene is missing. It is possible that this ORF has the 5Æ end of ALS4 fused to the 3Æ end of ALS2. That would explain too many repeat copies. Since the 3Æ ends of the two genes are nearly identical, there would be no way to tell if the sequences were wrongly joined. CandidaDB:CA1471 | CYGD:CA1471 | IPF:15450.3 | CandidaDB:CA1473 | CYGD:CA1473 | IPF:10205.2 C:cell wall (sensu Fungi) (ISS) F:cell adhesion molecule (ISS) P:flocculation (IEA) orf19.1099 Contig19-1684 471..1532 7 hypothetical protein in Major Repeat Sequence gene family gi|4589460|dbj|BAA76754.1| RPS; hypothetical [Candida albicans] | CandidaDB:CA0168 | CYGD:CA0168 | IPF:7001.1 orf19.11 Contig19-10011 complement(6101..6820) RX orf19.7684 | IPF27233.1 | Contig20011:complement(6809..6090) hypothetical protein CandidaDB:CA0650 | CYGD:CA0650 | IPF:11566.1 orf19.1100 Contig19-1684 3902..4216 7 hypothetical protein IPF:19843.2 orf19.1105 Contig19-10093 38..511 5 orf19.8701 | IPF26202.1 | Contig20093:2..511 hypothetical protein CandidaDB:CA0170 | CYGD:CA0170 | IPF:15959.2 orf19.1105.2 Contig19-10093 complement(1357..1611) 5 orf19.8701.2 | IPF17002.3 | Contig20093:complement(1611..1357) hypothetical protein CandidaDB:CA0171 | CYGD:CA0171 | IPF:15957.2 orf19.1105.3 Contig19-10093 join(2486..2725,2725..3198) 5 orf19.8702 | IPF26207.1 | Contig20093:2811..3209 hypothetical protein sequencing error? IPF:20047.1 orf19.1106 Contig19-10093 7268..9622 5 orf19.8703 | IPF26190.1 | Contig20093:7174..9624 hypothetical protein CandidaDB:CA1458 | CYGD:CA1458 | IPF:6342.1 orf19.1107 Contig19-10093 10531..11139 5 orf19.8704 | IPF26199.1 | Contig20093:10533..11141 conserved hypothetical protein CandidaDB:CA1459 | CYGD:CA1459 | IPF:6340.2 orf19.1108 Contig19-10093 complement(11309..11917) 5 HAM1 orf19.8705 | IPF26200.1 | Contig20093:complement(11919..11311) may function in DNA repair 3.6.1.15 CandidaDB:CA1460 | CYGD:CA1460 | IPF:6339.1 PF01725:Ham1p_like; Ham1 family:5.20E-45 COG0127 Xanthosine triphosphate pyrophosphatase 4e-64 orf19.1109 Contig19-10093 complement(12279..12671) 5 orf19.8706 | IPF26205.1 | Contig20093:complement(12673..12281) hypothetical protein CandidaDB:CA1461 | CYGD:CA1461 | IPF:6338.1 orf19.111 Contig19-10035 complement(45532..47238) 6O CAN1 orf19.7758 | IPF27165.1 | Contig20035:complement(46853..45147) arginine permease gene family CandidaDB:CA1191 | CYGD:CA1191 | IPF:11927.1 PF00324:aa_permeases; Amino acid permease:1.30E-187 C:plasma membrane (ISS) F:basic amino acid transporter (ISS) P:basic amino acid transport (ISS) orf19.1110 Contig19-10093 complement(13080..14063) 5 THI80 orf19.8707 | IPF6335.2 | Contig20093:complement(14062..13082) thiamin pyrophosphokinase 2.7.6.2 CandidaDB:CA1462 | CYGD:CA1462 | IPF:6334.3 COG1564 Thiamine pyrophosphokinase 1e-123 C:cellular_component

unknown (ND) F:thiamin pyrophosphokinase (ISS) | F:thiamin pyrophosphokinase (ISS) P:thiamin biosynthesis (ISS) orf19.1111 Contig19-10093 14265..14963 5 TAF9 orf19.8708 | IPF18669.1 | Contig20093:14265..14954 TFIID and SAGA subunit CandidaDB:CA1804 | CYGD:CA1804 | IPF:6333.3 PF02291:TFIID-31; Transcription initiation factor IID, 31kD subunit:1.60E-55 C:SAGA complex (ISS) | C:TFIID complex (ISS) F:general RNA polymerase II transcription factor (ISS) P:G1-specific transcription in mitotic cell cycle (ISS) | P:G1-specific transcription in mitotic cell cycle (ISS) | P:chromatin modification (ISS) | P:establishment and/or maintenance of chromatin architecture (ISS) | P:histone acetylation (ISS) | P:protein amino acid acetylation (ISS) | P:transcription initiation from Pol II promoter (ISS) | P:transcription initiation from Pol II promoter (ISS) | P:transcription initiation from Pol II promoter (ISS) orf19.1112 Contig19-10093 15313..17607 5 BUD7 orf19.8709 | IPF26191.1 | Contig20093:15304..17598 involved in bud-site selection CandidaDB:CA1805 | CYGD:CA1805 | IPF:6332.2 C:cellular_component unknown (ND) F:molecular_function unknown (ND) P:bud site selection (ISS) orf19.1113 Contig19-10093 18080..18847 5 orf19.8710 | IPF26197.1 | Contig20093:18071..18838 hypothetical protein CandidaDB:CA1806 | CYGD:CA1806 | IPF:6329.2 orf19.1114 Contig19-10093 complement(join(19038..19461,19579..19622)) complement(19462..19578) 5 orf19.8711 | IPF26204.1 | Contig20093:complement(19430..19029) conserved hypothetical protein Possible intron (size=117) gtatgtaaag...tttcaactag CandidaDB:CA1807 | CYGD:CA1807 | IPF:6328.2 orf19.1115 Contig19-10093 complement(19960..20532) 5 GUK1 orf19.8712 | IPF26196.1 | Contig20093:complement(20592..19951) guanylate kinase 2.7.4.8 CandidaDB:CA1808 | CYGD:CA1808 | IPF:6326.2 PF00625:Guanylate_kin; Guanylate kinase:7.90E- 57 COG1116 ABC-type nitrate/sulfonate/taurine/bicarbonate transport systems, ATPase components 4e-13\nCOG0410 High-affinity branched- chain amino acid transport system ATPase 1e-33\nCOG1136 ABC-type (unclassified) transport system, ATPase component 1e-14 C:cellular_component unknown (ND) F:guanylate kinase (IEA) P:GMP metabolism (ISS) orf19.1116 Contig19-10093 21320..21946 5 orf19.8713 | IPF26198.1 | Contig20093:21311..21937 hypothetical protein CandidaDB:CA1809 | CYGD:CA1809 | IPF:6325.2 orf19.1117 Contig19-10093 23124..24263 5 FDH3 orf19.8714 | IPF19255.2 | Contig20093:23115..24254 formate dehydrogenase 1.2.1.2 CandidaDB:CA1810 | CYGD:CA1810 | IPF:6323.2 PF02826:2-Hacid_DH_C; D-isomer specific 2- hydroxyacid dehydrogenase, NAD binding domain:2.70E-76 C:cellular_component unknown (ND) F:formate dehydrogenase (ISS) P:NADH regeneration (ISS) | P:formate catabolism (ISS) orf19.1119 Contig19-10093 24669..27548 5 MTR10 orf19.8717 | IPF13881.3 | Contig20093:25906..27558 involved in nuclear protein import CandidaDB:CA1811 | CYGD:CA1811 | IPF:6321.2 C:cytoplasm (ISS) | C:nucleus (ISS) F:nuclear localization sequence binding (ISS) | F:nuclear localization sequence binding (ISS) P:mRNA-binding (hnRNP) protein-nucleus import (ISS) | P:mRNA-binding (hnRNP) protein-nucleus import (ISS) | P:mRNA-binding (hnRNP) protein-nucleus import (ISS) | P:mRNA-binding (hnRNP) protein-nucleus import (ISS) | P:mRNA-binding (hnRNP) protein-nucleus import (ISS) | P:mRNA-binding (hnRNP) protein-nucleus import (ISS) | P:protein-nucleus import (ISS) | P:protein-nucleus import

(ISS) | P:protein- nucleus import (ISS) | P:protein-nucleus import (ISS) | P:protein-nucleus import (ISS) | P:protein-nucleus import (ISS) orf19.1120 Contig19-10093 complement(28254..28679) 5 orf19.8718 | IPF26203.1 | Contig20093:complement(28719..28255) hypothetical protein CandidaDB:CA1812 | CYGD:CA1812 | IPF:13879.2 orf19.1121 Contig19-10093 complement(31774..32595) 5 orf19.8719 | IPF2329.1 | Contig20093:complement(32606..31782) conserved hypothetical protein CandidaDB:CA1813 | CYGD:CA1813 | IPF:13871.1 orf19.1122 Contig19-10093 complement(33110..33952) 5 orf19.8720 | IPF2328.2 | Contig20093:complement(33963..33121) hypothetical protein CandidaDB:CA0360 | CYGD:CA0360 | IPF:13870.2 orf19.1123 Contig19-10093 34349..34702 5 orf19.8721 | IPF26211.1 | Contig20093:34357..34713 hypothetical protein IPF:29575.1 orf19.1124 Contig19-10093 34784..35668 5 orf19.8722 | IPF26195.1 | Contig20093:34795..35679 phytanoyl-CoA dioxygenase (PhyH) CandidaDB:CA0361 | CYGD:CA0361 | IPF:2326.2 orf19.1124.2 Contig19-10093 35981..>36202 5 DPH52 orf19.8722.3 | IPF26215.1 | Contig20093:35992..36213 diphthamide methyltransferase truncated protein IPF:2323.3 C:cellular_component unknown (ND) F:diphthine synthase (ISS) | F:diphthine synthase (IEA) P:peptidyl- diphthamide biosynthesis from peptidyl-histidine (ISS) orf19.1125 Contig19-1690 467..1303 2 conserved hypothetical protein gene family IPF:16630.3 orf19.1126 Contig19-1690 3822..4220 2 hypothetical protein gene family CandidaDB:CA0172 | CYGD:CA0172 | IPF:19154.1 orf19.1128 Contig19-1698 complement(2..1387) MYO4 class II myosin | myosin-1 isoform (type II myosin) heavy chain Overlap with orf19.6294 IPF:14354.2 PF00063:myosin_head; Myosin head (motor domain):2.30E-36 C:contractile ring (sensu Saccharomyces) (ISS) F:microfilament motor (ISS) P:axial budding (ISS) | P:cytokinesis (ISS) | P:response to osmotic stress (ISS) orf19.1129 Contig19-1698 complement(6093..>6710) SNF52 chromatin remodeling Snf/Swi complex subunit Overlap with orf19.5871 | truncated protein IPF:27539.1 C:nucleosome remodeling complex (ISS) F:general RNA polymerase II transcription factor (ISS) P:chromatin modeling (ISS) orf19.113 Contig19-10035 complement(48947..49846) 6O CIP1 orf19.7761 | IPF11929.2 | Contig20035:complement(49427..48528) closely related to cadmium-induced protein CIP1 gene family 1.3.1.45 CandidaDB:CA1190 | CYGD:CA1190 | IPF:14967.2 orf19.1130 Contig19-10096 1228..3000 1 orf19.8723 | IPF26187.1 | Contig20096:1228..3000 hypothetical protein CandidaDB:CA0182 | CYGD:CA0182 | IPF:6166.2 orf19.1133 Contig19-10096 6068..>9808 1 MSB1 orf19.8726 | IPF6172.3 | Contig20096:6055..9771 polarity establishment and bud formation protein truncated protein | tRNA Tyr anticodon GTA, Cove score 63.29 CandidaDB:CA0525 | CYGD:CA0525 | IPF:29571.1 P:establishment of cell polarity (sensu Saccharomyces) (NR)

orf19.1135 Contig19-10097 complement(1075..3510) 1X CKU70 orf19.8728 | IPF19699.2 | Contig20097:complement(3510..1075) Ku family DNA binding and repair protein IPF:20050.1 PF02735:ku; Ku70/Ku80 beta-barrel domain:2.70E-14 P:DNA repair (IEA) orf19.1136 Contig19-10097 3784..4221 1X APS2 orf19.8729 | IPF16570.2 | Contig20097:3778..4215 similar to the AP-2 complex sigma2 subunit CandidaDB:CA0568 | CYGD:CA0568 | IPF:4688.1 PF01217:Clat_adaptor_s; Clathrin adaptor complex small chain:1.40E-69 C:AP-2 adaptor complex (ISS) F:molecular_function unknown (ND) P:vesicle-mediated transport (ISS) orf19.1137 Contig19-10097 complement(4284..4958) 1X CDC8 orf19.8730 | IPF16571.2 | Contig20097:complement(4951..4277) thymidylate kinase 2.7.4.9 CandidaDB:CA0569 | CYGD:CA0569 | IPF:4687.1 PF02223:Thymidylate_kin; Thymidylate kinase:2.20E-48 COG0194 Guanylate kinase 5e-26\nCOG0125 Thymidylate kinase 4e-37\nCOG1121 ABC-type Mn/Zn transport systems, ATPase component 2e-24\nCOG1131 ABC-type multidrug transport system, ATPase component 1e- 26\nCOG1130 ABC-type sugar/spermidine/putrescine transport systems, ATPase component 1e-22\nCOG1428 Deoxyguanosine/deoxyadenosine kinase 1e-21 C:cytoplasm (ISS) | C:nucleus (ISS) F:thymidylate kinase (ISS) | F:thymidylate kinase (ISS) P:DNA dependent DNA replication (ISS) | P:DNA dependent DNA replication (ISS) | P:DNA dependent DNA replication (ISS) | P:DNA repair (ISS) | P:dTDP biosynthesis (ISS) | P:dTTP biosynthesis (ISS) | P:mutagenesis (ISS) | P:mutagenesis (ISS) | P:plasmid maintenance (ISS) orf19.1139 Contig19-10097 8082..11006 1X SVL3 orf19.8732 | IPF17015.2 | Contig20097:8077..11007 involved in vacuole function CandidaDB:CA0570 | CYGD:CA0570 | IPF:29554.1 COG0739 Membrane proteins related to metalloendopeptidases 7e-18\nCOG1340 Uncharacterized archaeal coiled-coil domain 3e-19\nCOG1566 Multidrug resistance efflux pump 2e-16\nCOG1372 Inteins 1e-16 C:cellular_component unknown (ISS) F:molecular_function unknown (ISS) P:endocytosis (ISS) orf19.114 Contig19-10035 complement(51332..52330) 6O orf19.7762 | IPF19622.2 | Contig20035:complement(52932..50896) hypothetical protein IPF:19689.1 orf19.1140 Contig19-10097 11578..12204 1X orf19.8733 | IPF17749.2 | Contig20097:11565..12191 hypothetical protein CandidaDB:CA0955 | CYGD:CA0955 | IPF:13160.2 orf19.1142 Contig19-10097 complement(12425..14344) 1X AVT4 orf19.8735 | IPF26160.1 | Contig20097:complement(14331..12412) related to the neuronal GABA vesicular transporters CandidaDB:CA0954 | CYGD:CA0954 | IPF:13162.2 PF01490:Aa_trans; Transmembrane amino acid transporter protein:1.90E-96 orf19.1143 Contig19-10097 complement(15344..16528) 1X orf19.8736 | IPF26165.1 | Contig20097:complement(16515..15331) hypothetical protein IPF:20069.1 orf19.1144 Contig19-10097 complement(16959..20324) 1X orf19.8737 | IPF26180.1 | Contig20097:complement(20905..16946) conserved hypothetical protein Could very well be shorter on the N-terminus than stated, since homologs are shorter and match the downstream end only. If so, then a putative ORF covering about 400nt of a different frame in the N-terminus may be real, though lacking any homology of its own. CandidaDB:CA0953 | CYGD:CA0953 | IPF:13166.3 COG0790 TPR repeat proteins 9e-48 orf19.1146 Contig19-10097 complement(20557..20925) 1X hypothetical protein IPF:29564.1

orf19.1148 Contig19-10097 23590..24195 1X orf19.8740 | IPF19912.1 | Contig20097:23570..24361 hypothetical protein IPF:29559.1 orf19.1149 Contig19-10097 25376..26455 1X ETR1 orf19.8742 | IPF11717.2 | Contig20097:25354..26433 mitochondrial╩2-enoyl thioester reductase 1.6.5.5 CandidaDB:CA1333 | CYGD:CA1333 | IPF:14722.3 PF00107:adh_zinc; Zinc-binding dehydrogenase:8.60E-15 C:nucleus (ISS) F:DNA binding (ISS) P:respiratory gaseous exchange (ISS) orf19.115 Contig19-10035 complement(52531..53184) 6O hypothetical protein IPF:19623.1 orf19.1150 Contig19-10097 complement(26693..28111) 1X GLN32 orf19.8743 | IPF26163.1 | Contig20097:complement(28089..26671) zinc finger transcription factor CandidaDB:CA1332 | CYGD:CA1332 | IPF:11716.1 PF00320:GATA; GATA zinc finger:7.60E-21 C:nucleus (ISS) F:transcription factor (ISS) P:nitrogen metabolism (ISS) orf19.1150.1 Contig19-10097 29687..29908 1X orf19.8743.2 | IPF26154.1 | Contig20097:29665..29886 hypothetical protein CandidaDB:CA1331 | CYGD:CA1331 | IPF:11714.1 orf19.1151 Contig19-10097 complement(29978..30340) 1X orf19.8744 | IPF11713.1 | Contig20097:complement(30753..29956) very weakly conserved hypothetical protein IPF:29561.1 orf19.1152 Contig19-10097 complement(30361..30774) 1X orf19.8744 | IPF11713.1 | Contig20097:complement(30753..29956) hypothetical protein IPF:19733.2 orf19.1153 Contig19-10097 complement(31582..33288) 1X GAD1 orf19.8745 | IPF11712.3 | Contig20097:complement(33560..31854) glutamate decarboxylase 4.1.1.15 CandidaDB:CA1564 | CYGD:CA1564 | IPF:7609.1 PF00282:pyridoxal_deC; Pyridoxal-dependent decarboxylase conserved domain:8.40E-49 COG0076 Glutamate decarboxylase and related PLP-dependent proteins 1e-104 C:cytoplasm (ISS) F:glutamate decarboxylase (IEA) P:amino acid metabolism (ISS) orf19.1154 Contig19-10097 complement(34379..34852) 1X EGD1 orf19.8746 | IPF26175.1 | Contig20097:complement(35124..34651) beta subunit of the nascent-polypeptide-associated complex (NAC) CandidaDB:CA1565 | CYGD:CA1565 | IPF:7610.1 PF01849:NAC; NAC domain:2.90E-22 C:nascent polypeptide-associated complex (ISS) F:chaperone (ISS) P:nascent polypeptide association (ISS) orf19.1155 Contig19-10097 35586..36440 1X DPP3 orf19.8747 | IPF26170.1 | Contig20097:35822..36712 vacuolar diacylglycerol pyrophosphate phosphatase CandidaDB:CA1566 | CYGD:CA1566 | IPF:7611.1 PF01569:PAP2; PAP2 superfamily:1.60E-21 C:cytoplasm (ISS) | C:endoplasmic reticulum (ISS) F:phosphatidate phosphatase (ISS) P:phospholipid metabolism (ISS) orf19.1156 Contig19-10097 36886..38040 1X orf19.8748 | IPF26166.1 | Contig20097:37158..38312 hypothetical protein CandidaDB:CA1567 | CYGD:CA1567 | IPF:7613.1 PF00018:SH3; SH3 domain:6.90E-05 C:membrane fraction (ISS) F:molecular_function unknown (ISS) P:Rho protein signal transduction (ISS) | P:cell wall organization and biogenesis (ISS) | P:response to heat (ISS) orf19.1158 Contig19-10097 complement(38099..38992) 1X orf19.8750 | IPF26169.1 | Contig20097:complement(39324..38371) hypothetical protein CandidaDB:CA1568 | CYGD:CA1568 | IPF:7615.1

orf19.1159 Contig19-10097 39170..40690 1X MET23 orf19.8751 | IPF26162.1 | Contig20097:39499..40962 homoserine O-acetyltransferase 2.3.1.31 CandidaDB:CA1569 | CYGD:CA1569 | IPF:7616.2 PF00561:abhydrolase; alpha/beta hydrolase fold:3.90E-10 C:cytoplasm (ISS) F:homoserine O-acetyltransferase (IEA) P:homoserine metabolism (ISS) | P:methionine biosynthesis (ISS) orf19.1160 Contig19-10097 complement(40748..41395) 1X orf19.8752 | IPF26172.1 | Contig20097:complement(41667..41020) conserved hypothetical protein CandidaDB:CA1570 | CYGD:CA1570 | IPF:7617.2 orf19.1161 Contig19-10097 complement(41705..46837) 1X PLD1 PLD1 orf19.8753 | IPF13085.3 | Contig20097:complement(47109..41977) phospholipase D gene family 3.1.4.4 gi|3413518|dbj|BAA32278.1| phospholipase D [Candida albicans] | CandidaDB:CA0587 | CYGD:CA0587 | IPF:29560.1 PF00614:PLDc; Phospholipase D. Active site motif:2.10E-08 nCOG1502 Phosphatidylserine/phosphatidylglycerophosphate/cardiol ipin synthases and related enzymes 5e-45 C:prospore membrane (ISS) F:phospholipase D (IEA) P:meiosis (ISS) orf19.1162 Contig19-10097 complement(47355..47732) 1X orf19.8755 | IPF18931.2 | Contig20097:complement(48004..47627) aromatic ring-cleaving dioxygenase CandidaDB:CA0588 | CYGD:CA0588 | IPF:13081.2 orf19.1162.1 Contig19-10097 complement(47958..48521) 1X orf19.8755.1 | IPF26174.1 | Contig20097:complement(48829..48230) conserved hypothetical protein no available methionine CandidaDB:CA0589 | CYGD:CA0589 | IPF:13080.1 orf19.1163 Contig19-10097 48733..49824 1X orf19.8756 | IPF13079.1 | Contig20097:49005..50096 conserved hypothetical protein CandidaDB:CA0590 | CYGD:CA0590 | IPF:7620.2 PF01926:MMR_HSR1; GTPase of unknown function:8.80E-07 COG0218 Predicted GTPases 3e-33\nCOG2262 GTPases 1e-30 orf19.1164 Contig19-10097 complement(50010..50570) 1X GAR1 orf19.8757 | IPF13076.1 | Contig20097:complement(50872..50282) nucleolar rRNA processing protein CandidaDB:CA1789 | CYGD:CA1789 | IPF:7621.1 COG3277 RNA-binding protein involved in rRNA processing 1e-45 P:35S primary transcript processing (ISS) | P:rRNA modification (ISS) orf19.1166 Contig19-10097 join(50968..50983,51086..54960) 50984..51085 1X orf19.8759 | IPF26181.1 | Contig20097:51405..55262 conserved hypothetical protein Possible intron (size=102) gtatgtattg...caaaaaatag CandidaDB:CA1788 | CYGD:CA1788 | IPF:7623.2 PF00627:UBA; UBA/TS-N domain:3.30E-10 COG2433 Uncharacterized ACR 6e-38 C:actin cortical patch (sensu Saccharomyces) (ISS) | C:bud neck (ISS) | C:bud tip (ISS) F:molecular_function unknown (ND) P:endocytosis (ISS) orf19.1167 Contig19-10097 55551..56711 1X orf19.8760 | IPF26164.1 | Contig20097:55853..57013 alpha-ketoglutarate catabolism dioxygenase gene family CandidaDB:CA1787 | CYGD:CA1787 | IPF:19929.1 PF02668:TauD; Taurine catabolism dioxygenase TauD, TfdA family:6.50E-78 orf19.1168 Contig19-10097 57221..57808 1X potential fungal Zn(2)-Cys(6) binuclear cluster domain DNA binding factor CandidaDB:CA1786 | CYGD:CA1786 | IPF:7629.2 PF00172:Zn_clus; Fungal Zn(2)-Cys(6) binuclear cluster domain:7.50E-04 orf19.1169 Contig19-10097 58592..59542 1X orf19.8762 | IPF26167.1 | Contig20097:58894..59844 conserved hypothetical

protein CandidaDB:CA1785 | CYGD:CA1785 | IPF:7631.2 PF00226:DnaJ; DnaJ domain:6.50E-10 orf19.117 Contig19-10035 54094..55686 6O SEC9 orf19.7764 | IPF19868.1 | Contig20035:53635..55215 plasma membrane t-SNARE CandidaDB:CA0483 | CYGD:CA0483 | IPF:14761.2 PF00835:SNAP-25; SNAP-25 family:7.10E-58 C:membrane (ISS) F:v-SNARE (ISS) P:Golgi to plasma membrane transport (ISS) | P:non-selective vesicle fusion (ISS) orf19.1170 Contig19-10097 59825..60631 1X orf19.8763 | IPF26168.1 | Contig20097:60127..60933 chorismate mutase 5.4.99.5 CandidaDB:CA1784 | CYGD:CA1784 | IPF:7632.1 PF01817:Chorismate_mut; Chorismate mutase:6.70E-14 COG1605 Chorismate mutase 1e-124 C:cellular_component unknown (ND) F:chorismate mutase (IEA) P:aromatic amino acid family biosynthesis (ISS) orf19.1171 Contig19-10097 62108..64366 1X orf19.8764 | IPF26156.1 | Contig20097:62170..64668 S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase | lipid metabolism CandidaDB:CA1783 | CYGD:CA1783 | IPF:7635.2 orf19.1172 Contig19-10097 complement(65137..>65988) 1X PHO84 orf19.8765 | IPF26171.1 | Contig20097:complement(66125..65439) inorganic phosphate permease truncated protein CandidaDB:CA1782 | CYGD:CA1782 | IPF:7638.2 C:integral plasma membrane protein (ISS) | C:integral plasma membrane protein (ISS) F:inorganic phosphate transporter (ISS) | F:inorganic phosphate transporter (ISS) P:phosphate transport (ISS) | P:phosphate transport (ISS) orf19.1173 Contig19-1712 complement(3518) DPH6 diphthamide biosynthesis truncated protein IPF:16546.1 C:cellular_component unknown (ND) F:molecular_function unknown (ND) P:peptidyl-diphthamide biosynthesis from peptidyl-histidine (ISS) orf19.1175 Contig19-10099 47..400 6O orf19.8766 | IPF not available | Contig20099:47..400 hypothetical protein IPF:not available orf19.1177 Contig19-10099 1411..2640 6O RTT106 orf19.8769 | IPF26139.1 | Contig20099:1410..2639 regulator of Ty1 transposition CandidaDB:CA0192 | CYGD:CA0192 | IPF:15134.2 C:cellular_component unknown (ND) F:molecular_function unknown (ND) P:negative regulation of DNA transposition (ISS) orf19.1178 Contig19-10099 complement(717..1322) 6O orf19.8768 | IPF18909.2 | Contig20099:complement(1322..717) hypothetical protein IPF:15133.2 orf19.1179 Contig19-10099 complement(2653..2985) 6O orf19.8770 | IPF19608.1 | Contig20099:complement(3034..2477) hypothetical protein IPF:19609.1 orf19.118 Contig19-10035 57736..59046 6O ODD1 orf19.7765 | IPF14763.2 | Contig20035:57258..58568 oleate delta-12 desaturase 1.3.1.35 CandidaDB:CA0482 | CYGD:CA0482 | IPF:29951.1 PF00487:FA_desaturase; Fatty acid desaturase:1.00E-49 orf19.1180 Contig19-10099 3174..4421 6O orf19.8771 | IPF13098.2 | Contig20099:3173..4420 conserved hypothetical protein

2.6.1.66 CandidaDB:CA0675 | CYGD:CA0675 | IPF:19848.2 COG1167 Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs 3e-67 orf19.1181 Contig19-10099 4629..5717 6O DPP4 orf19.8772 | IPF13097.2 | Contig20099:4628..5716 diacylglycerol pyrophosphate phosphatase CandidaDB:CA0676 | CYGD:CA0676 | IPF:29548.1 PF01569:PAP2; PAP2 superfamily:8.30E-27 COG0671 Membrane-associated phospholipid phosphatase 3e-89 C:cytoplasm (ISS) | C:endoplasmic reticulum (ISS) F:phosphatidate phosphatase (ISS) P:phospholipid metabolism (ISS) orf19.1182 Contig19-10099 complement(5712..6605) 6O VAM7 orf19.8773 | IPF13095.1 | Contig20099:complement(6604..5711) vacuolar morphogenesis protein gi|7271034|emb|CAB77652.1| hypothetical protein [Candida albicans] | CandidaDB:CA0677 | CYGD:CA0677 | IPF:13903.2 PF00787:PX; PX domain:7.90E-11 C:vacuolar membrane (sensu Fungi) (ISS) F:v-SNARE (ISS) P:Golgi to vacuole transport (ISS) | P:non- selective vesicle fusion (ISS) orf19.1183 Contig19-10099 6749..8395 6O orf19.8774 | IPF13094.1 | Contig20099:6748..8394 conserved hypothetical protein CandidaDB:CA0678 | CYGD:CA0678 | IPF:13902.1 orf19.1185 Contig19-10099 8565..9674 6O orf19.8776 | IPF13090.3 | Contig20099:9329..10462 conserved hypothetical protein CandidaDB:CA2646 | CYGD:CA2646 | IPF:13899.2 PF00498:FHA; FHA domain:4.70E-17 orf19.1186 Contig19-10099 9848..10540 6O orf19.8777 | IPF13897.2 | Contig20099:10692..11330 hypothetical protein CandidaDB:CA2647 | CYGD:CA2647 | IPF:13088.1 orf19.1187 Contig19-10099 12316..14877 6O CPH2 CPH2 orf19.8778 | IPF13893.3 | Contig20099:13102..15663 bHLH DNA-binding protein that promotes hyphal development This 731 amino acid protein is far longer than the 290 aa protein originally reported. | There is little reason to accept the validity of a putative intron at aa 631 to 754. CandidaDB:CA2648 | CYGD:CA2648 | IPF:9062.2 PF00010:HLH; Helix-loop-helix DNA-binding domain:1.10E-07 C:cellular_component unknown (ND) F:transcription factor (ISS) P:pseudohyphal growth (ISS) orf19.1189 Contig19-10099 19523..21577 6O orf19.8780 | IPF19121.2 | Contig20099:20302..22356 hypothetical protein CandidaDB:CA2649 | CYGD:CA2649 | IPF:9057.2 C:centromere (ISS) | C:kinetochore (ISS) F:DNA bending (ISS) | F:centromeric DNA binding (ISS) P:mitosis (IEA) orf19.119 Contig19-10035 complement(join(59294..60020,60020..60090)) 6O STE14 orf19.7766 | IPF14764.1 | Contig20035:complement(59613..58816) farnesyl cysteine-carboxyl methyltransferase gene family | sequencing error? 2.1.1.100 CandidaDB:CA0481 | CYGD:CA0481 | IPF:29956.1 C:endoplasmic reticulum membrane (ISS) | C:endoplasmic reticulum membrane (ISS) F:protein-S- isoprenylcysteine O-methyltransferase (ISS) | F:protein-S- isoprenylcysteine O-methyltransferase (ISS) P:pheromone processing (ISS) orf19.1190 Contig19-10099 complement(23596..26427) 6O VPH3 orf19.8781 | IPF9052.3 | Contig20099:complement(27215..24384) vacuolar ATPase V0 domain subunit a 3.6.3.6 CandidaDB:CA2650 | CYGD:CA2650 | IPF:13604.2 PF01496:V_ATPase_sub_a; V-type ATPase 116kDa subunit family:0.00E+00 C:hydrogen-transporting ATPase V0 domain (ISS) | C:hydrogen-transporting ATPase V0 domain (ISS) F:hydrogen-transporting two-sector ATPase (ISS) | F:hydrogen-transporting two-sector ATPase (ISS) P:polyphosphate metabolism (ISS) | P:vacuolar acidificati

orf19.1191 Contig19-10099 26921..29341 6O HRD3 orf19.8782 | IPF26127.1 | Contig20099:27709..30129 responsible for ER-associated degradation (ERAD) of numerous ER-resident proteins CandidaDB:CA2651 | CYGD:CA2651 | IPF:13605.2 C:endoplasmic reticulum (ISS) F:ubiquitin-protein ligase (ISS) P:ER-associated protein catabolism (ISS) orf19.1192 Contig19-10099 complement(29394..33674) 6O DNA2 orf19.8783 | IPF26141.1 | Contig20099:complement(34462..30182) DNA helicase involved in DNA replication CandidaDB:CA2652 | CYGD:CA2652 | IPF:15025.2 COG1702 Phosphate starvation-inducible protein PhoH, predicted ATPase 3e-32\nCOG1468 RecB family exonuclease 2e-50\nCOG1198 Primosomal protein N' (replication factor Y) - superfamily II helicase 2e-32 C:nucleus (ISS) F:ATP dependent DNA helicase (ISS) | F:single-stranded DNA specific endodeoxyribonuclease (ISS) P:DNA dependent DNA replication (ISS) | P:DNA repair (ISS) orf19.1193 Contig19-10099 complement(34131..35870) 6O GNP2 orf19.8784 | IPF7152.2 | Contig20099:complement(36659..34920) high-affinity glutamine permease Possibly missing some N-terminal by homology CandidaDB:CA1373 | CYGD:CA1373 | IPF:29546.1 C:plasma membrane (ISS) F:amino acid permease (ISS) | F:amino acid transporter (ISS) P:amino acid transport (ISS) orf19.1195 Contig19-10099 complement(37402..39753) 6O OCT1 orf19.8786 | IPF26128.1 | Contig20099:complement(40410..38191) mitochondrial intermediate peptidase involved in protein import 3.4.24.70 | 3.4.24.15 CandidaDB:CA1374 | CYGD:CA1374 | IPF:7154.2 PF01432:Peptidase_M3; Peptidase family M3:3.20E-106 COG1164 Oligoendopeptidase F 2e-98\nCOG0339 Zn- dependent oligopeptidases 0.0 C:mitochondrion (ISS) F:metallopeptidase (ISS) P:iron homeostasis (ISS) | P:mitochondrial processing (ISS) orf19.1196 Contig19-10099 40661..43246 6O orf19.8787 | IPF7158.2 | Contig20099:41450..44035 conserved hypothetical protein with ser/thr kinase domain 2.7.1.37 CandidaDB:CA1375 | CYGD:CA1375 | IPF:29542.1 PF00069:pkinase; Protein kinase domain:1.90E- 77 orf19.1198 Contig19-10099 complement(43438..43983) 6O orf19.8789 | IPF7159.2 | Contig20099:complement(44773..44228) conserved hypothetical protein CandidaDB:CA1376 | CYGD:CA1376 | IPF:29549.1 orf19.1199 Contig19-10099 complement(44229..45779) 6O NOP58 orf19.8790 | IPF18691.2 | Contig20099:complement(46565..45018) part of small (ribosomal) subunit (SSU) processosome; U3 snoRNP protein CandidaDB:CA1438 | CYGD:CA1438 | IPF:7161.1 PF01798:Nop; Putative snoRNA binding domain:5.10E-91 C:small nuclear ribonucleoprotein complex (ISS) | C:small nucleolar ribonucleoprotein complex (ISS) F:snoRNA binding (ISS) P:35S primary transcript processing (ISS) | P:processing of 20S pre-rRNA (ISS) | P:rRNA modification (ISS) orf19.1200 Contig19-10099 complement(46244..47239) 6O orf19.8791 | IPF26140.1 | Contig20099:complement(48025..47030) hypothetical protein CandidaDB:CA1437 | CYGD:CA1437 | IPF:7163.1 orf19.1201 Contig19-10099 47295..48785 6O DIA4 orf19.8792 | IPF26135.1 | Contig20099:48144..49571 similar to bacterial seryl-tRNA synthases 6.1.1.11 CandidaDB:CA1436 | CYGD:CA1436 | IPF:7165.1 PF00587:tRNA-synt_2b; tRNA synthetase class II core domain (G, H, P, S and T):4.30E-40 C:cellular_component unknown (ND) F:serine-tRNA

ligase (ISS) P:aerobic respiration (IEP) | P:invasive growth (ISS) | P:pseudohyphal growth (ISS) orf19.1202 Contig19-10099 complement(48832..50166) 6O orf19.8793 | IPF26137.1 | Contig20099:complement(50952..49618) hypothetical protein CandidaDB:CA1435 | CYGD:CA1435 | IPF:7166.2 orf19.1203 Contig19-10099 complement(50396..53626) 6O SRO77 orf19.8794 | IPF26148.1 | Contig20099:complement(54394..51182) suppressor of defect in the small GTPase Rho3p CandidaDB:CA1434 | CYGD:CA1434 | IPF:12463.2 P:non-selective vesicle exocytosis (ISS) orf19.1203.1 Contig19-10099 53986..54249 6O orf19.8794.1 | IPF26149.1 | Contig20099:54808..55035 conserved hypothetical protein start placed by homology, not first met; presumptive sequencing error at N-term. CandidaDB:CA1433 | CYGD:CA1433 | IPF:12464.1 orf19.1204 Contig19-10099 complement(54383..55921) 6O APM3 orf19.8795 | IPF26134.1 | Contig20099:complement(56737..55169) clathrin associated AP-3 protein complex, medium subunit CandidaDB:CA1432 | CYGD:CA1432 | IPF:12465.2 PF00928:Adap_comp_sub; Adaptor complexes medium subunit family:1.50E-09 C:AP-3 adaptor complex (ISS) F:molecular_function unknown (ND) P:Golgi to vacuole transport (ISS) orf19.1206 Contig19-10099 complement(56454..>57824) 6O FET34 orf19.8797 | IPF26138.1 | Contig20099:complement(58460..57240) iron transport multicopper oxidase truncated protein | gene family 1.10.3.3 | 1.10.3.2 CandidaDB:CA1431 | CYGD:CA1431 | IPF:12467.2 PF00394:Cu-oxidase; Multicopper oxidase:5.60E- 22 COG2132 Putative multicopper oxidases 1e-159 C:plasma membrane (ISS) F:multicopper ferroxidase iron transport mediator (ISS) | F:multicopper ferroxidase iron transport mediator (ISS) P:high affinity iron transport (ISS) orf19.1207 Contig19-1722 3220..3552 hypothetical protein IPF:27537.1 orf19.1208 Contig19-1722 complement(5697..>7139) MRS512 involved in fungal induction gene family | truncated protein IPF:19849.1 orf19.1209 Contig19-10101

orf19.1214 Contig19-10101 complement(6829..8172) 6X MAP2 orf19.8802 | IPF26119.1 | Contig20101:complement(8228..6885) methionine aminopeptidase, isoform 2 3.4.11.18 CandidaDB:CA1534 | CYGD:CA1534 | IPF:9511.2 PF00557:Peptidase_M24; metallopeptidase family M24:1.60E-57 F:methionyl aminopeptidase (ISS) P:proteolysis and peptidolysis (ISS) orf19.1215 Contig19-10101 9209..10552 6X orf19.8803 | IPF9510.2 | Contig20101:9265..10608 hypothetical protein CandidaDB:CA1533 | CYGD:CA1533 | IPF:29538.1 orf19.1217 Contig19-10101 complement(10653..13289) 6X orf19.8806 | IPF9507.2 | Contig20101:complement(15178..10709) conserved hypothetical protein IPF:16011.2 orf19.1219 Contig19-10101 complement(13801..15003) 6X conserved hypothetical protein IPF:29539.1 orf19.122 Contig19-10035 63909..65813 6O CDC20 orf19.7769 | IPF13908.2 | Contig20035:63359..65335 anaphase promoting complex (APC) subunit CandidaDB:CA1218 | CYGD:CA1218 | IPF:19430.2 PF00400:WD40; WD domain, G-beta repeat:3.00E- 04 | PF00400:WD40; WD domain, G-beta repeat:1.50E-02 | PF00400:WD40; WD domain, G-beta repeat:5.20E-02 | PF00400:WD40; WD domain, G-beta repeat:3.20E-01 C:anaphase-promoting complex (ISS) F:enzyme activator (ISS) P:cyclin catabolism (ISS) | P:mitotic chromosome segregation (ISS) | P:mitotic metaphase/anaphase transition (ISS) | P:mitotic spindle elongation (ISS) | P:ubiquitin-dependent protein catabolism (ISS) orf19.1220 Contig19-10101 15485..16807 6X RVS167 orf19.8807 | IPF26118.1 | Contig20101:15540..16862 cytoskeletal binding and regulatory protein 2.7.1.112 CandidaDB:CA1531 | CYGD:CA1531 | IPF:9505.1 PF03114:BAR; BAR domain:4.30E-88 COG1269 Archaeal/vacuolar-type H+-ATPase subunit I 2e-19 C:actin cortical patch (sensu Saccharomyces) (ISS) F:cytoskeletal protein binding (ISS) | F:cytoskeletal protein binding (ISS) P:endocytosis (ISS) | P:polar budding (ISS) | P:response to osmotic stress (ISS) orf19.1221 Contig19-10101 complement(17028..18314) 6X ALG2 orf19.8808 | IPF26120.1 | Contig20101:complement(18369..17083) mannosyltransferase CandidaDB:CA1530 | CYGD:CA1530 | IPF:9503.2 PF00534:Glycos_transf_1; Glycosyl transferases group 1:1.40E-24 F:glycolipid mannosyl transferase (ISS) P:oligosaccharide-lipid intermediate assembly (ISS) orf19.1222 Contig19-1725 158..4204 4 ELP1 IKI3 RNA polymerase II Elongator subunit CandidaDB:CA0204 | CYGD:CA0204 | IPF:15693.2 C:DNA-directed RNA polymerase II, holoenzyme (ISS) | C:transcription elongation factor complex (ISS) F:Pol II transcription elongation factor (ISS) | F:Pol II transcription elongation factor (ISS) | F:histone acetyltransferase (ISS) P:regulation of transcription from Pol II promoter (ISS) orf19.1223 Contig19-10103 complement(130..2145) 2 DBF2 orf19.8809 | IPF26112.1 | Contig20103:complement(2262..130) kinase required for late nuclear division 2.7.1.37 CandidaDB:CA0205 | CYGD:CA0205 | IPF:13853.2 PF00069:pkinase; Protein kinase domain:2.50E- 61 C:bud neck (ISS) | C:spindle pole body (ISS) F:protein kinase (ISS) P:cell cycle (IEA) orf19.1224 Contig19-10103 7446..8303 2 ADY2 orf19.8810 | IPF13846.3 | Contig20103:7379..8230 putative transmembrane transporter CandidaDB:CA0415 | CYGD:CA0415 | IPF:16160.1 PF01184:Grp1_Fun34_YaaH;

GPR1/FUN34/yaaH family:1.70E-111 C:cellular_component unknown (ND) F:molecular_function unknown (ND) P:DNA metabolism (ISS) | P:meiosis (IEP) orf19.1225 Contig19-10103 complement(9281..9904) 2 orf19.8811 | IPF26113.1 | Contig20103:complement(9850..9227) hypothetical protein CandidaDB:CA0416 | CYGD:CA0416 | IPF:17492.2 orf19.1226 Contig19-10104

aspartate 4-P- transferase) 2.7.2.4 CandidaDB:CA2977 | CYGD:CA2977 | IPF:14675.2 PF00696:aakinase; Amino acid kinase family:1.90E-50 COG0528 Uridylate kinase 8e-41\nCOG0527 Aspartokinases 1e-118 C:cellular_component unknown (ND) F:aspartate kinase (ISS) P:methionine metabolism (ISS) | P:threonine metabolism (ISS) orf19.1236 Contig19-10104 complement(34455..35420) 4H orf19.8821 | IPF14676.2 | Contig20104:complement(35455..34490) conserved hypothetical protein CandidaDB:CA2976 | CYGD:CA2976 | IPF:12543.2 orf19.1237 Contig19-10104 complement(35865..37436) 4H ARO9 orf19.8822 | IPF14677.1 | Contig20104:complement(37474..35903) aromatic amino acid aminotransferase II 2.6.1.66 CandidaDB:CA2975 | CYGD:CA2975 | IPF:12542.2 C:cellular_component unknown (ND) F:aromatic amino acid transferase (ISS) P:aromatic amino acid family metabolism (ISS) orf19.1238 Contig19-10104 complement(join(37840..39328,39409..39416)) complement(39329..39408) 4H TUB4 orf19.8823 | IPF26076.1 | Contig20104:complement(39359..37878) gamma tubulin Possible intron (size=80) gtaagtagca...cctaatttag gi|4240020|dbj|BAA74797.1| gamma-tubulin [Candida albicans] | CandidaDB:CA0159 | CYGD:CA0159 | IPF:12541.2 PF00091:tubulin; Tubulin/FtsZ family, GTPase domain:2.50E-68 C:inner plaque of spindle pole body (ISS) | C:outer plaque of spindle pole body (ISS) F:structural constituent of cytoskeleton (ISS) P:microtubule nucleation (ISS) | P:mitotic spindle assembly (sensu Saccharomyces) (ISS) orf19.1239 Contig19-10104 complement(40372..41358) 4H orf19.8824 | IPF12540.1 | Contig20104:complement(41409..40423) hypothetical protein CandidaDB:CA2974 | CYGD:CA2974 | IPF:29520.1 orf19.124 Contig19-10035 67601..68698 6O CIC1 orf19.7771 | IPF27169.1 | Contig20035:67104..68201 protease substrate recruitment factor CandidaDB:CA0020 | CYGD:CA0020 | IPF:7046.2 C:26S proteasome (ISS) | C:26S proteasome (ISS) F:protease substrate recruitment factor (ISS) | F:protease substrate recruitment factor (ISS) | F:protease substrate recruitment factor (ISS) P:protein catabolism (ISS) | P:protein catabolism (ISS) | P:protein catabolism (ISS) orf19.1240 Contig19-10104 43704..51911 4H orf19.8825 | IPF26084.1 | Contig20104:43851..51962 conserved hypothetical protein CandidaDB:CA1261 | CYGD:CA1261 | IPF:9887.3 orf19.1244 Contig19-10104 53028..55856 4H GYP2 MIC1, MDR1 (but this is already another gene in candida) orf19.8829 | IPF26053.1 | Contig20104:53079..55907 GTPase activating protein (GAP) for Ypt6 and Mac1 intercting protein CandidaDB:CA1262 | CYGD:CA1262 | IPF:9881.2 PF00566:TBC; TBC domain:1.80E-84 C:soluble fraction (ISS) F:RAB GTPase activator (ISS) | F:RAB GTPase activator (ISS) P:biological_process unknown (ISS) orf19.1246 Contig19-10104 complement(56205..59336) 4H orf19.8830 | IPF15574.3 | Contig20104:complement(59261..56256) hypothetical protein CandidaDB:CA1263 | CYGD:CA1263 | IPF:9880.2 orf19.1247 Contig19-10104 complement(59795..60256) 4H orf19.8831 | IPF15575.2 | Contig20104:complement(60307..59846) hypothetical protein IPF:18723.2 orf19.1248 Contig19-10104 60492..61448 4H RPB3 orf19.8832 | IPF15576.2 | Contig20104:60541..61497 45 kDa subunit of RNA polymerase II IPF:18722.2 C:DNA-directed RNA

polymerase II, core (ISS) F:DNA- directed RNA polymerase II (ISS) P:transcription from Pol II promoter (ISS) orf19.1249 Contig19-10104 complement(61518..62357) 4H HIS6 orf19.8833 | IPF26083.1 | Contig20104:complement(62406..61567) phosphoribosyl-5-amino-1-phosphoribosyl-4-imidazolecarboxiamide isomerase 5.3.1.16 gi|10444341|gb|AAG17873.1|AF290199_1 5-proFAR isomerase [Candida albicans] | CandidaDB:CA1480 | CYGD:CA1480 | IPF:15577.2 COG1411 Archaeal family of HisA paralogs 6e- 30\nCOG0042 Predicted TIM-barrel enzymes, possibly dehydrogenases, nifR3 family 3e-20\nCOG0107 Imidazoleglycerol-phosphate synthase 2e-66\nCOG0106 Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase 2e-59\nCOG1304 L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases 1e-25 C:cell (ISS) F:1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino)imidazole-4- carboxamide isomerase (ISS) P:histidine biosynthesis (ISS) orf19.125 Contig19-10035 complement(68951..70174) 6O EBP1 orf19.7772 | IPF7044.2 | Contig20035:complement(69677..68454) NADH:flavin oxidoreductase (old yellow enzyme) 1.6.99.1 | 1.3.1.42 | 1.5.8.2 gi|410053|gb|AAA18013.1| estrogen-binding protein | CandidaDB:CA1216 | CYGD:CA1216 | IPF:29953.1 PF00724:oxidored_FMN; NADH:flavin oxidoreductase / NADH oxidase family:1.30E-191 COG1902 NADH:flavin oxidoreductases, Old Yellow Enzyme family 1e-131 C:cellular_component unknown (ND) F:NADPH dehydrogenase (ISS) | F:NADPH dehydrogenase (ISS) P:biological_process unknown (ISS) | P:biological_process unknown (ND) orf19.1250 Contig19-10104 62561..63547 4H orf19.8834 | IPF26082.1 | Contig20104:62610..63596 conserved hypothetical protein CandidaDB:CA1479 | CYGD:CA1479 | IPF:16428.2 orf19.1251 Contig19-10104 complement(63583..65820) 4H BRN1 orf19.8835 | IPF26062.1 | Contig20104:complement(65869..63632) functional homologue of human BRRN1 involved in chromosome segregation CandidaDB:CA1478 | CYGD:CA1478 | IPF:16426.2 C:condensin (ISS) | C:nucleus (ISS) F:molecular_function unknown (ND) P:mitotic chromosome condensation (ISS) orf19.1252 Contig19-10104 68004..70067 4H YME1 orf19.8836 | IPF26065.1 | Contig20104:67978..70116 mitochondrial protein of the CDC48/PAS1/SEC18 family of ATPases CandidaDB:CA1477 | CYGD:CA1477 | IPF:14644.2 PF01434:Peptidase_M41; Peptidase family M41:2.50E-104 C:mitochondrial inner membrane (ISS) | C:mitochondrion (ISS) F:ATP-dependent peptidase (ISS) P:mitochondrion organization and biogenesis (ISS) orf19.1253 Contig19-10104 71866..73845 4H PHO4 orf19.8838 | IPF14649.2 | Contig20104:71917..73896 myc-family transcription factor CandidaDB:CA3452 | CYGD:CA3452 | IPF:10541.2 PF00010:HLH; Helix-loop-helix DNA-binding domain:6.00E-03 C:cytoplasm (ISS) | C:nucleus (ISS) F:transcription factor (ISS) P:phosphate metabolism (ISS) | P:response to phosphate starvation (ISS) | P:response to phosphate starvation (ISS) orf19.1254 Contig19-10104 74365..76653 4H SEC23 orf19.8839 | IPF26061.1 | Contig20104:74416..76704 component of COPII coat of ER- golgi vesicles CandidaDB:CA3453 | CYGD:CA3453 | IPF:10536.2 C:COPII vesicle coat (ISS) | C:cytoplasm (ISS) F:GTPase activator (ISS) P:ER to Golgi transport (ISS) | P:ER to Golgi transport (ISS) | P:autophagy (ISS) orf19.1255 Contig19-10104 join(78629..>81016,

IPF26091.1 | Contig20104:81059..81586 hypothetical protein with zinc finger domain sequencing error? CandidaDB:CA3454 | CYGD:CA3454 | IPF:10533.2 | CandidaDB:CA3455 | CYGD:CA3455 | IPF:19641.1 PF00172:Zn_clus; Fungal Zn(2)-Cys(6) binuclear cluster domain:2.70E-10 C:nucleus (ISS) F:DNA binding (ISS) | F:transcription factor (ISS) P:carbohydrate metabolism (ISS) | P:regulation of transcription, DNA-dependent (ISS) orf19.1257 Contig19-10104 85091..85423 4H hypothetical protein IPF:29533.1 orf19.1258 Contig19-10104 86307..87020 4H orf19.8843 | IPF15051.2 | Contig20104:86146..86859 hypothetical protein CandidaDB:CA0066 | CYGD:CA0066 | IPF:29522.1 orf19.1259 Contig19-10104 complement(87200..91531) 4H SNT2 orf19.8844 | IPF26095.1 | Contig20104:complement(91368..87037) conserved hypothetical protein CandidaDB:CA3456 | CYGD:CA3456 | IPF:19986.1 PF00628:PHD; PHD-finger:5.20E-17 orf19.1260 Contig19-10104 complement(92142..92843) 4H LEA1 orf19.8845 | IPF26087.1 | Contig20104:complement(92680..91979) similar to human U2AsnRNP protein CandidaDB:CA3457 | CYGD:CA3457 | IPF:8521.1 PF00560:LRR; Leucine Rich Repeat:1.00E-01 C:cytoplasm (ISS) | C:snRNP U2 (ISS) F:pre-mRNA splicing factor (ISS) P:mRNA splicing (ISS) orf19.1261 Contig19-10104 join(93089..93244,93247..94437) 4H CEG1 orf19.8846 | IPF26081.1 | Contig20104:93018..94274 | orf19.8845.1 | IPF18334.2 | Contig20104:92926..93084 mRNA capping enzyme alpha subunit and guanylyltransferase sequencing error? 2.7.7.50 CandidaDB:CA3459 | CYGD:CA3459 | IPF:8518.2 | CandidaDB:CA3458 | CYGD:CA3458 | IPF:8519.1 PF01331:mRNA_cap_enzyme; mRNA capping enzyme, catalytic domain:6.50E-157 C:nucleus (ISS) F:mRNA guanylyltransferase (ISS) P:mRNA capping (ISS) orf19.1263 Contig19-10104 complement(94668..96950) 4H FRE1 CFL1 orf19.8848 | IPF26060.1 | Contig20104:complement(96787..94505) ferric reductase gene family gi|5139350|emb|CAB45649.1| ferric reductase [Candida albicans] | CandidaDB:CA3460 | CYGD:CA3460 | IPF:8516.2 PF01794:Ferric_reduct; Ferric reductase like transmembrane component:2.50E-216 C:plasma membrane (ISS) F:ferric-chelate reductase (ISS) P:copper uptake transport (ISS) | P:iron transport (ISS) orf19.1264 Contig19-10104 complement(99394..101610) 4H FRE2 orf19.8849 | IPF26059.1 | Contig20104:complement(101447..99231) ferric reductase gene family CandidaDB:CA3461 | CYGD:CA3461 | IPF:8512.2 PF01794:Ferric_reduct; Ferric reductase like transmembrane component:4.00E-199 C:plasma membrane (ISS) | C:plasma membrane (ISS) F:ferric-chelate reductase (ISS) | F:ferric-chelate reductase (ISS) P:iron-siderochrome transport (ISS) orf19.1265 Contig19-10104 104995..108789 4H TRS130 orf19.8850 | IPF26103.1 | Contig20104:104835..108629 targeting complex (TRAPP) component involved in ER to Golgi membrane traffic CandidaDB:CA3462 | CYGD:CA3462 | IPF:14959.2 C:TRAPP (ISS) F:molecular_function unknown (ND) P:ER to Golgi transport (ISS) orf19.1266 Contig19-10104 complement(109759..110124) 4H orf19.8852 | IPF10280.1 | Contig20104:complement(109781..109464) hypothetical protein IPF:14956.3 orf19.1267 Contig19-10104 110797..112182 4H CAJ1 orf19.8853 | IPF10278.2 | Contig20104:110637..112022 similar to E. coli DnaJ CandidaDB:CA0945 | CYGD:CA0945 | IPF:29519.1 PF00226:DnaJ; DnaJ domain:3.10E-36 COG0576 Molecular chaperone GrpE (heat

shock protein) 6e-41 C:cellular_component unknown (ND) F:chaperone regulator (ISS) P:biological_process unknown (ND) orf19.1267.1 Contig19-10104 112534..112800 4H orf19.8853.1 | IPF26052.1 | Contig20104:112374..112640 conserved hypothetical protein CandidaDB:CA0946 | CYGD:CA0946 | IPF:10277.2 orf19.1268 Contig19-10104 113013..113354 4H orf19.8854 | IPF26094.1 | Contig20104:112751..113194 hypothetical protein IPF:29526.1 orf19.1270 Contig19-10104 113693..115876 4H FRE3 orf19.8856 | IPF26063.1 | Contig20104:113536..115716 ferric reductase gene family CandidaDB:CA0947 | CYGD:CA0947 | IPF:10273.2 PF01794:Ferric_reduct; Ferric reductase like transmembrane component:5.80E-120 C:integral membrane protein (ISS) | C:plasma membrane (ISS) F:ferric-chelate reductase (ISS) P:iron homeostasis (IEP) | P:iron homeostasis (IEP) | P:iron homeostasis (ISS) | P:iron homeostasis (ISS) | P:iron- siderochrome transport (ISS) orf19.1272 Contig19-10104 complement(116160..117398) 4H orf19.8858 | IPF26080.1 | Contig20104:complement(117238..116000) conserved hypothetical protein CandidaDB:CA0948 | CYGD:CA0948 | IPF:10270.2 orf19.1273 Contig19-10104 118224..118616 4H GIM3 orf19.8859 | IPF10269.1 | Contig20104:118064..118456 prefoldin subunit 4 IPF:29523.1 C:cytoplasm (ISS) P:protein folding (IEA) orf19.1274 Contig19-10104 complement(119164..120855) 4H hypothetical protein IPF:10266.2 orf19.1275 Contig19-10104 124377..126380 4H GAT1 orf19.8862 | IPF26064.1 | Contig20104:124199..126202 activator of transcription of nitrogen-regulated genes CandidaDB:CA1410 | CYGD:CA1410 | IPF:12290.2 PF00320:GATA; GATA zinc finger:1.40E-22 C:nucleus (ISS) F:specific RNA polymerase II transcription factor (ISS) P:regulation of nitrogen utilization (ISS) | P:transcription initiation from Pol II promoter (ISS) orf19.1276 Contig19-10104 126851..127357 4H orf19.8863 | IPF26090.1 | Contig20104:126673..127179 weakly conserved hypothetical protein IPF:12292.2 orf19.1277 Contig19-10104 complement(127587..128765) 4H orf19.8864 | IPF19348.2 | Contig20104:complement(128818..127409) hypothetical protein CandidaDB:CA1411 | CYGD:CA1411 | IPF:11858.2 orf19.1278 Contig19-10104 complement(131624..>132028) 4H orf19.8865 | IPF26100.1 | Contig20104:complement(131715..131473) conserved hypothetical protein truncated protein CandidaDB:CA1412 | CYGD:CA1412 | IPF:11854.3 C:vacuolar membrane (sensu Fungi) (ISS) F:molecular_function unknown (ND) P:Golgi to endosome transport (ISS) | P:homotypic vacuole fusion (non- autophagic) (ISS) | P:late endosome to vacuole transport (ISS) | P:non-selective vesicle docking (ISS) orf19.1279 Contig19-10105 complement(1933..3288) 5 CDS1 orf19.8866 | IPF26045.1 | Contig20105:complement(3198..1933) CDP-diacylglycerol synthase 2.7.7.41 CandidaDB:CA0213 | CYGD:CA0213 | IPF:16312.2 PF01148:CTP_transf_1; Phosphatidate cytidylyltransferase:2.40E-78 COG0575 CDP-diglyceride synthetase 1e-115 C:endoplasmic reticulum (ISS) | C:mitochondrion (ISS) F:phosphatidate cytidylyltransferase

(ISS) P:phosphatidylglycerol biosynthesis (ISS) | P:phosphatidylserine metabolism (ISS) orf19.1280 Contig19-10105 4731..5060 5 SUI1 orf19.8867 | IPF10374.1 | Contig20105:4730..5059 translation initiation factor eIF3 subunit CandidaDB:CA2367 | CYGD:CA2367 | IPF:29514.1 PF01253:SUI1; Translation initiation factor SUI1:3.40E-57 COG0023 Translation initiation factor (SUI1) 1e-37 C:ribosome (ISS) F:translation initiation factor (ISS) P:translational initiation (ISS) orf19.1281 Contig19-10105 5594..6259 5 orf19.8868 | IPF26047.1 | Contig20105:5593..6258 conserved hypothetical protein CandidaDB:CA2366 | CYGD:CA2366 | IPF:10373.1 orf19.1282 Contig19-10105 7220..7528 5 CKS1 orf19.8869 | IPF26050.1 | Contig20105:7219..7527 cyclin-dependent kinases regulatory subunit CandidaDB:CA2365 | CYGD:CA2365 | IPF:10371.2 PF01111:CKS; Cyclin-dependent kinase regulatory subunit:7.20E-46 C:cellular_component unknown (ND) F:molecular_function unknown (ISS) P:regulation of cell cycle (ISS) orf19.1283 Contig19-10105 7996..14973 5 MEC1 orf19.8870 | IPF19757.1 | Contig20105:7995..14972 cell cycle checkpoint protein 2.7.1.137 CandidaDB:CA2364 | CYGD:CA2364 | IPF:29511.1 PF00454:PI3_PI4_kinase; Phosphatidylinositol 3- and 4-kinase:5.10E-85 | PF02259:FAT; FAT domain:5.00E- 21 | PF02260:FATC; FATC domain:4.80E-12 C:cellular_component unknown (ND) F:inositol/phosphatidylinositol kinase (ISS) P:DNA damage checkpoint (ISS) | P:DNA recombination (ISS) | P:DNA replication checkpoint (ISS) | P:meiotic recombination (ISS) orf19.1285 Contig19-10105 complement(15019..17814) 5 orf19.8872 | IPF26042.1 | Contig20105:complement(17939..15018) conserved hypothetical protein CandidaDB:CA2363 | CYGD:CA2363 | IPF:10590.2 orf19.1286 Contig19-10105 20301..20657 5 orf19.8873 | IPF26049.1 | Contig20105:20267..20656 hypothetical protein IPF:29513.1 orf19.1287 Contig19-10105 complement(24432..25574) 5 orf19.8874 | IPF26046.1 | Contig20105:complement(25573..24431) hypothetical protein CandidaDB:CA2362 | CYGD:CA2362 | IPF:10595.1 orf19.1288 Contig19-1739 complement(

aminobenzoic acid (PABA) synthase (ISS) P:ribosomal large subunit nucleus export (ISS) orf19.1294 Contig19-1748 complement(4528..>6240) 4 coiled coil protein similar to myosin truncated protein IPF:10478.3 PF02370:M; M protein repeat:4.60E-04 orf19.1295 Contig19-10108 complement(676..3921) VAS1 orf19.8875 | IPF26041.1 | Contig20108:complement(3933..688) valyl-tRNA synthetase 6.1.1.9 CandidaDB:CA0223 | CYGD:CA0223 | IPF:13980.2 PF00133:tRNA-synt_1; tRNA synthetases class I (I, L, M and V):0.00E+00 COG0525 Valyl-tRNA synthetase 0.0\nCOG0060 Isoleucyl-tRNA synthetase 0.0 C:cytoplasm (ISS) | C:mitochondrion (ISS) F:valine- tRNA ligase (ISS) P:valyl-tRNA aminoacylation (ISS) orf19.1296 Contig19-10108 complement(4356..>5006) PRP31 orf19.8876 | IPF26039.1 | Contig20108:complement(5036..4368) pre-mRNA splicing protein truncated protein CandidaDB:CA0224 | CYGD:CA0224 | IPF:13982.2 COG1498 Protein implicated in ribosomal biogenesis, Nop56p homolog 9e-51 C:small nuclear ribonucleoprotein complex (ISS) F:pre-mRNA splicing factor (ISS) P:mRNA splicing (IEA) | P:mRNA splicing (ISS) orf19.1297 Contig19-10109 complement(419..1642) 4N CVT20 orf19.8877 | IPF26018.1 | Contig20109:complement(1642..419) cytoplasm to vacuole targeting CandidaDB:CA0226 | CYGD:CA0226 | IPF:16024.1 PF00787:PX; PX domain:6.20E-19 orf19.1298 Contig19-10109 2778..5312 4N NUP84 orf19.8878 | IPF26014.1 | Contig20109:2778..4487 nuclear pore complex subunit CandidaDB:CA0225 | CYGD:CA0225 | IPF:16027.3 C:nuclear pore (ISS) F:structural molecule (ISS) P:NLS-bearing substrate-nucleus import (ISS) | P:mRNA- binding (hnRNP) protein-nucleus import (ISS) | P:mRNA- nucleus export (ISS) | P:nuclear membrane organization and biogenesis (ISS) | P:nuclear pore organization and biogenesis (ISS) | P:protein-nucleus export (ISS) | P:rRNA- nucleus export (ISS) | P:ribosomal protein-nucleus import (ISS) | P:snRNA-nucleus export (ISS) | P:snRNP protein- nucleus import (ISS) | P:tRNA-nucleus export (ISS) orf19.1299 Contig19-10109 complement(5350..6657) 4N RPN6 orf19.8879 | IPF13551.2 | Contig20109:complement(6832..5345) proteasome regulatory particle subunit CandidaDB:CA0454 | CYGD:CA0454 | IPF:29495.1 PF01399:PCI; PCI domain:2.70E-24 C:19S proteasome regulatory particle (ISS) | C:19S proteasome regulatory particle (ISS) F:proteasome endopeptidase (ISS) | F:proteasome endopeptidase (ISS) P:ubiquitin-dependent protein catabolism (ISS) | P:ubiquitin-dependent protein catabolism (ISS) orf19.13 Contig19-10011 7651..9069 RX GLK3 orf19.7686 | IPF27232.1 | Contig20011:7640..9058 glucokinase, aldohexose specific gene family of about 10 members IPF:11564.1 PF00349:hexokinase; Hexokinase:8.00E-179 C:cytosol (ISS) F:glucokinase (ISS) P:carbohydrate metabolism (ISS) orf19.130 Contig19-10035 complement(join(71778..72188,72188..72967,72971..74407,74409..76394)) 6O VPS15 orf19.7773 | IPF7041.2 | Contig20035:complement(72453..71275) | orf19.7775 | IPF27168.1 | Contig20035:complement(73983..72463) | orf19.7776 | IPF7035.2 | Contig20035:complement(75889..73901) vacuolar protein sorting protein kinase sequencing error? 2.7.1.37 | 2.7.1.123 IPF:19493.2 | IPF:29955.1 | CandidaDB:CA1214 | CYGD:CA1214 | IPF:7038.2 | CandidaDB:CA1213 | CYGD:CA1213 | IPF:29948.1 PF00400:WD40; WD domain, G-beta repeat:3.70E- 04 | PF00069:pkinase;

Protein kinase domain:1.70E- 11 C:Golgi membrane (ISS) F:protein serine/threonine kinase (ISS) P:Golgi retention (ISS) | P:protein- vacuolar targeting (ISS) | P:vacuolar transport (ISS) orf19.1300 Contig19-10109 6932..8266 4N orf19.8880 | IPF13552.2 | Contig20109:6921..8255 conserved hypothtical protein CandidaDB:CA0453 | CYGD:CA0453 | IPF:29494.1 PF01209:Ubie_methyltran; ubiE/COQ5 methyltransferase family:1.10E-04 orf19.1301 Contig19-10109 complement(8383..8877) 4N orf19.8881 | IPF13554.1 | Contig20109:complement(8866..8372) hypothetical protein CandidaDB:CA0452 | CYGD:CA0452 | IPF:18704.2 orf19.1302 Contig19-10109 complement(9616..10266) 4N orf19.8882 | IPF13556.2 | Contig20109:complement(10259..9612) hypothetical protein CandidaDB:CA0451 | CYGD:CA0451 | IPF:29496.1 orf19.1303 Contig19-10109 11222..12406 4N MRF1 orf19.8883 | IPF19627.2 | Contig20109:11157..12395 mitochondrial polypeptide chain release factor CandidaDB:CA1329 | CYGD:CA1329 | IPF:19626.1 PF00472:RF-1; Peptidyl-tRNA hydrolase domain:2.30E-54 COG0210 Superfamily I DNA and RNA helicases 2e- 12\nCOG0216 Protein chain release factor A 1e-139\nCOG1186 Protein chain release factor B 1e-127 C:mitochondrion (ISS) | C:mitochondrion (ISS) F:translation release factor (ISS) | F:translation release factor (ISS) P:protein biosynthesis (ISS) | P:protein biosynthesis (ISS) | P:translational termination (ISS) | P:translational termination (ISS) orf19.1304 Contig19-10109 complement(12517..13431) 4N RRP4 orf19.8884 | IPF6681.3 | Contig20109:complement(13420..12506) rRNA processing exoribonuclease complex component CandidaDB:CA1328 | CYGD:CA1328 | IPF:6682.2 COG1097 RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain) 8e-68\nCOG1185 Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) 5e-25\nCOG1095 DNA-directed RNA polymerase subunit E' 3e-21\nCOG1093 Translation initiation factor eIF2alpha 2e-29\nCOG0539 ribosomal protein S1 1e-51 C:cytoplasmic exosome (RNase complex) (ISS) | C:nuclear exosome (RNase complex) (ISS) F:3'-5' exoribonuclease (ISS) P:35S primary transcript processing (ISS) | P:mRNA catabolism (ISS) orf19.1305 Contig19-10109 13644..14993 4N TRM5 orf19.8885 | IPF26017.1 | Contig20109:13633..14982 ╩tRNA (guanine) methyltransferase CandidaDB:CA1327 | CYGD:CA1327 | IPF:6680.2 PF02475:Met_10; Met-10+ like-protein:1.30E-76 C:cytoplasm (ISS) F:molecular_function unknown (IEA) P:biological_process unknown (IEA) orf19.1306 Contig19-10109 15550..16560 4N orf19.8886 | IPF26019.1 | Contig20109:15539..16549 conserved oxidase 1.14.11.13 CandidaDB:CA1326 | CYGD:CA1326 | IPF:6679.1 PF03171:2OG-FeII_Oxy; 2OG-Fe(II) oxygenase superfamily:7.20E-19 orf19.1307 Contig19-10109 17069..18571 4N orf19.8887 | IPF26015.1 | Contig20109:17058..18560 conserved hypothetical protein CandidaDB:CA1325 | CYGD:CA1325 | IPF:6678.2 PF00892:DUF6; Integral membrane protein DUF6:1.30E-03 COG0697 Predicted permeases 5e-41 orf19.1308 Contig19-10109 complement(18635..20380) 4N orf19.8888 | IPF18658.2 | Contig20109:complement(20369..18624) MFS transporter CandidaDB:CA1324 | CYGD:CA1324 | IPF:6676.2 P:biological_process unknown (IEA)

orf19.1309 Contig19-10109 21126..21539 4N orf19.8889 | IPF6673.1 | Contig20109:21114..21527 hypothetical protein CandidaDB:CA1323 | CYGD:CA1323 | IPF:6675.2 orf19.131 Contig19-10035 76597..77271 6O orf19.7777 | IPF7033.2 | Contig20035:76092..76766 hypothetical protein CandidaDB:CA1212 | CYGD:CA1212 | IPF:29957.1 P:mRNA splicing (IEA) orf19.131.2 Contig19-10035 77555..77803 6O orf19.7777.2 | IPF7031.2 | Contig20035:76933..77298 hypothetical protein CandidaDB:CA1211 | CYGD:CA1211 | IPF:29965.1 orf19.1310 Contig19-10109 21962..23593 4N orf19.8890 | IPF6672.2 | Contig20109:21680..23581 similar to DNA repair protein Rad4 CandidaDB:CA1547 | CYGD:CA1547 | IPF:18706.2 PF03835:Rad4; DNA repair protein Rad4:1.10E- 11 orf19.1311 Contig19-10109 complement(23584..26169) 4N SPO75 orf19.8891 | IPF6671.2 | Contig20109:complement(26157..23572) related to yeast sporulation protein CandidaDB:CA1546 | CYGD:CA1546 | IPF:29492.1 PF02714:DUF221; Domain of unknown function DUF221:3.70E-76 orf19.1313 Contig19-10109 31554..36059 4N CDR3 CDR3 orf19.8893 | IPF26026.1 | Contig20109:31542..36047 opaque-specific multidrug resistance transporter CandidaDB:CA1545 | CYGD:CA1545 | IPF:14709.3 C:plasma membrane (ISS) F:xenobiotic-transporting ATPase (ISS) P:drug susceptibility/resistance (ISS) | P:drug transport (ISS) orf19.1314 Contig19-10109 37007..38416 4N orf19.8894 | IPF26016.1 | Contig20109:36995..38404 conserved hypothetical protein with Zn ring finger CandidaDB:CA2822 | CYGD:CA2822 | IPF:17153.2 orf19.1317 Contig19-10109 39608..42142 4N OSH3 orf19.8897 | IPF26009.1 | Contig20109:39596..42130 oxysterol binding protein CandidaDB:CA2823 | CYGD:CA2823 | IPF:14554.2 PF01237:Oxysterol_BP; Oxysterol-binding protein:1.80E-78 C:cytoplasm (ISS) F:oxysterol binding (ISS) P:steroid biosynthesis (ISS) orf19.1318 Contig19-10109 complement(42274..43347) 4N orf19.8898 | IPF26020.1 | Contig20109:complement(43335..42262) hypothetical protein CandidaDB:CA2824 | CYGD:CA2824 | IPF:17888.2 orf19.132 Contig19-10035 complement(77906..79687) 6O SIF2 orf19.7778 | IPF7030.3 | Contig20035:complement(79389..77401) Sir4p-Interacting Factor CandidaDB:CA1210 | CYGD:CA1210 | IPF:29947.1 PF00400:WD40; WD domain, G-beta repeat:2.90E- 03 | PF00400:WD40; WD domain, G-beta repeat:2.10E-02 | PF00400:WD40; WD domain, G-beta repeat:1.30E-01 | PF00400:WD40; WD domain, G-beta repeat:2.90E-01 | PF00400:WD40; WD domain, G-beta repeat:3.70E+00 C:histone deacetylase complex (ISS) | C:nucleus (ISS) F:NAD-dependent histone deacetylase (ISS) orf19.1321 Contig19-10109 complement(44251..46155) 4N HWP1 orf19.8901 | IPF26012.1 | Contig20109:complement(46143..44239) hyphal wall protein gi|1915979|gb|AAC96368.1| hyphal wall protein 1 [Candida albicans] | CandidaDB:CA2825 | CYGD:CA2825 | IPF:12916.1 C:plasma membrane (ISS) P:invasive growth (ISS) | P:pseudohyphal growth (ISS) orf19.1323 Contig19-10109 complement(48236..50551) 4N APL6 orf19.8903 | IPF26010.1 | Contig20109:complement(50539..48224) clathrin assembly complex beta adaptin component CandidaDB:CA2826 | CYGD:CA2826 | IPF:12906.2 PF01602:Adaptin_N; Adaptin N terminal region:2.70E-

49 C:AP-3 adaptor complex (ISS) F:molecular_function unknown (ND) P:Golgi to vacuole transport (ISS) orf19.1324 Contig19-10109 complement(50732..53704) 4N RAD2 orf19.8904 | IPF26007.1 | Contig20109:complement(53692..50720) structure-specific nuclease of the nucleotide excision repairosome 3.1.11.1 CandidaDB:CA2827 | CYGD:CA2827 | IPF:19770.1 PF00752:XPG_N; XPG N-terminal domain:1.70E-52 C:nucleotide excision repair factor 3 (ISS) F:single-stranded DNA specific endodeoxyribonuclease (ISS) P:nucleotide-excision repair, DNA incision, 3' to lesion (ISS) orf19.1325 Contig19-10109 54363..56123 4N ECM37 orf19.8905 | IPF26013.1 | Contig20109:54351..56111 gamma-glutamyltransferase 2.3.2.2 CandidaDB:CA2828 | CYGD:CA2828 | IPF:17026.2 PF01019:G_glu_transpept; Gamma- glutamyltranspeptidase:3.50E-104 COG0405 Gamma-glutamyltranspeptidase 0.0 C:cellular_component unknown (ND) F:protein- glutamine gamma-glutamyltransferase (ISS) P:cell wall organization and biogenesis (ISS) orf19.1326 Contig19-10109 complement(56276..58246) 4N orf19.8906 | IPF26011.1 | Contig20109:complement(58234..56264) hypothetical protein CandidaDB:CA2829 | CYGD:CA2829 | IPF:14593.2 PF00560:LRR; Leucine Rich Repeat:4.70E-07 orf19.1327 Contig19-10109 61661..63805 4N RBT1 orf19.8907 | IPF19252.2 | Contig20109:61643..63787 repressed by Tup1, related to HWP1 3.2.1.18 CandidaDB:CA2830 | CYGD:CA2830 | IPF:15385.2 orf19.1329 Contig19-10110 complement(

orf19.1336 Contig19-10110 20113..20733 7 PUP3 orf19.8916 | IPF8017.2 | Contig20110:20102..20722 20S proteasome subunit beta3 3.4.25.1 CandidaDB:CA2120 | CYGD:CA2120 | IPF:8018.1 PF00227:proteasome; Proteasome A-type and B- type:1.80E-35 C:20S core proteasome (ISS) | C:20S core proteasome (ISS) F:proteasome endopeptidase (ISS) | F:proteasome endopeptidase (ISS) P:ubiquitin-dependent protein catabolism (ISS) | P:ubiquitin-dependent protein catabolism (ISS) orf19.1336.2 Contig19-10110 complement(20974..21273) 7 orf19.8916.1 | IPF26004.1 | Contig20110:complement(21263..20964) conserved hypothetical protein CandidaDB:CA0034 | CYGD:CA0034 | IPF:8016.2 orf19.1338 Contig19-10110 22000..23094 7 orf19.8918 | IPF7930.1 | Contig20110:21990..23084 conserved hypothetical protein IPF:19386.2 orf19.1339 Contig19-10110 complement(23352..24980) 7 CPY1 CPY1 orf19.8919 | IPF18540.1 | Contig20110:complement(24733..23342) serine carboxypeptidase Y precursor gene family 3.4.16.5 gi|7597001|gb|AAA34326.2| carboxypeptidase Y precursor [Candida albicans] | CandidaDB:CA0430 | CYGD:CA0430 | IPF:7928.2 PF00450:serine_carbpept; Serine carboxypeptidase:7.00E-257 C:cytoplasm (ISS) | C:endoplasmic reticulum (ISS) F:carboxypeptidase C (ISS) P:vacuolar protein catabolism (ISS) orf19.134 Contig19-10035 83759..84169 6O hypothetical protein CandidaDB:CA1818 | CYGD:CA1818 | IPF:7023.2 orf19.1340 Contig19-10110 25797..26726 7 orf19.8920 | IPF18538.2 | Contig20110:25775..26704 aldose reductase 1.1.1.21 CandidaDB:CA0431 | CYGD:CA0431 | IPF:7927.1 PF00248:aldo_ket_red; Aldo/keto reductase family:1.30E-76 orf19.1341 Contig19-10110 26864..27820 7 PRR2 orf19.8921 | IPF25999.1 | Contig20110:26842..27798 serine/threonine kinase CandidaDB:CA0432 | CYGD:CA0432 | IPF:7926.1 PF00069:pkinase; Protein kinase domain:3.90E- 42 C:cellular_component unknown (ND) F:receptor signaling protein serine/threonine kinase (ISS) | F:receptor signaling protein serine/threonine kinase (ISS) P:MAPKKK cascade (ISS) orf19.1342 Contig19-10110 28099..29580 7 SHM1 SHM1 orf19.8922 | IPF19725.2 | Contig20110:28076..29557 serine hydroxymethyltransferase I gene family 2.1.2.1 gi|2282056|gb|AAB64196.1| serine hydroxymethyltransferase I [Candida albicans] | CandidaDB:CA0433 | CYGD:CA0433 | IPF:7924.2 PF00464:SHMT; Serine hydroxymethyltransferase:3.00E-297 COG1104 Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes 8e- 50\nCOG0436 PLP-dependent aminotransferases 3e-60\nCOG0112 Glycine hydroxymethyltransferase 1e-99 C:mitochondrion (ISS) F:glycine hydroxymethyltransferase (ISS) P:one-carbon compound metabolism (ISS) orf19.1343 Contig19-10110 29850..33008 7 SIN4 orf19.8923 | IPF7922.2 | Contig20110:29830..32991 RNA polymerase II holoenzyme/mediator subunit CandidaDB:CA1243 | CYGD:CA1243 | IPF:17576.2 C:mediator complex (ISS) P:transcription from Pol II promoter (ISS) orf19.1344 Contig19-10110 complement(33182..33850) 7 orf19.8924 | IPF26000.1 | Contig20110:complement(33992..33165) hypothetical protein CandidaDB:CA1242 | CYGD:CA1242 | IPF:19908.1 orf19.1345 Contig19-10110 36784..38166 7 LIP8 LIP8 orf19.8925 | IPF7914.2 | Contig20110:36766..38148 secreted lipase gene

family CandidaDB:CA1241 | CYGD:CA1241 | IPF:29487.1 PF03583:LIP; Secretory

mannosyltransferase:6.90E-212 C:Golgi apparatus (ISS) - A... · transport (ISS) | P:vesicle-...

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Transcript of mannosyltransferase:6.90E-212 C:Golgi apparatus (ISS) - A... · transport (ISS) | P:vesicle-...