Loss of Lean Body Mass Can Lead to Functional Decline Body... · 2019-12-31 · • LBM loss can...
Transcript of Loss of Lean Body Mass Can Lead to Functional Decline Body... · 2019-12-31 · • LBM loss can...
• LBM loss increases with age3-7
• Sarcopenia is the loss of skeletal muscle mass and function, which occurs with advancing
age and compromises recovery and survival8
Complications increase with greater LBM loss1
Loss of lean body mass (LBM) and strength is associated with malnutrition and is also evident with aging3-7
90%
80%
70%
60%
50%
40%
25 YRS 40 YRS 70 YRS 80 YRS
ZO
NE
WH
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E R
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O
F D
EA
TH
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HIG
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% O
F M
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CL
E M
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PER DECADE LOSS FROM 40 TO 70
PER DECADE LOSS AFTER AGE 70
AGE
8%
LOSS
15%
LOSS
• LBM loss can affect strength, walking, rising out of a chair, climbing stairs, and risk of falls2
100%
50%
30%
10%
% LOSS OF LEAN BODY MASS
- Impaired immunity- Increased infection
- Decreased healing
- Too weak to sit- Increased risk of pneumonia- Wound healing stops
- Death, usually due to pneumonia
10%
10%
30%
50%
100%
% M
OR
TA
LIT
Y R
ISK
20% 30% 40%
To learn more about how LBM loss and sarcopenia affect your patients, visit fightsarcopenia.com, or contact your Abbott sales representative.
Loss of Lean Body Mass Can Lead to Functional Decline1,2
HMB can help reduce protein degradation in skeletal muscle cells.11
*Study Design A randomized, controlled trial evaluated the effect of HMB on muscle decline during 10 days of complete bed rest in women 60 to 79 years of age. Subjects were randomized to receive HMB (n=11) or control (n=8) for 5 days before and 8 weeks after bed rest.
References: 1. Demling RH. Eplasty. 2009;9:65-94. 2. Morley JE, et al. J Cachexia Sarcopenia Muscle. 2014;5:253-259. 3. Baier S, et al. JPEN J Parenter Enteral Nutr. 2009;33:71-82. 4. Flakoll P, et al. Nutrition. 2004;20(5):445-451. 5. Grimby G, et al. Acta Physiol Scand. 1982;115:125-134. 6. Janssen I, et al. J Appl Physiol. 2000;89:81-88. 7. Vandewoude MF, et al. J Aging Res. 2012;2012:651570. Epub 2012 Sep 13. 8. Cruz-Jentoft AJ, et al. Age Ageing. 2014;43:748-759. 9. Data on file. Abbott Nutrition. 10. Deutz NE, et al. A randomized, placebo-controlled clinical trial of readmission and mortality in malnourished, older, hospitalized adults treated with a specialized oral nutrition supplement. ASPEN Clinical Nutrition Week 2016. Austin, TX. 11. Eley HL, et al. Am J Physiol Endocrinol Metab. 2008;295:E1417-E1426. 12. Deutz NE, et al. Clin Nutr. 2013;32:704-712.
©2015 Abbott Laboratories 150585/December 2015 LITHO IN USA
HMB preserves muscle in older adults12*
HMB +PROTEIN
LO
SS
OF
LE
AN
BO
DY
MA
SS
(L
BS
.)
-2.05 kg/-4.5 lbs P=0.02
-0.17 kg/-0.4 lbs P=0.23
Control
-5
-4
-3
-2
-1
0HMB
Less muscle loss with HMB
12X
#Doctor
RECOMMENDEDBRAND
NEW Ensure Enlive has a patented formula to help improve patient outcomes.9,10
New Ensure® Enlive® has HMB + 20g Protein
1.5g of CaHMB
26 vitamins and minerals
350 kcal 350 kcal
120% DV of vitamin D(50% more)
N/A
26 vitamins and minerals
80% DV of vitamin D
20g of high-quality protein(53% more)
13g of high-quality protein
2X/Day
Two servings per day are recommended to help rebuild lost muscleassociated with malnutrition.
New Ensure Enliveper 8 fl oz
Ensure® Plusper 8 fl oz