Long term complications of MVP

• In most studies, MVP has a complication rate of less than 2 percent per year2,15 .

• The age-adjusted survival rate in men and women with MVP is similar to that in patients without this common clinical disorder

Complications of Mitral Valve Prolapse

Atrial fibrillation and other arrhythmiasCongestive heart failurePulmonary hypertensionRuptured mitral valve chordaeInfective endocarditisCentral nervous system embolic events

O'Rourke RA. The mitral valve prolapse syndrome. In: Chizner MA, ed. Classic teachings in clinical cardiology. Cedar Grove, N.J.: Laennec, 1996:1049-70.

Congestive Heart Failure

progressive dilation of the left atrium and left ventricle

atrial fibrillation, moderate to severe mitral regurgitation

LV dysfunction

congestive heart failure

Gradual progression of mitral regurgitation

Infective Endocarditis• a serious complication of

MVP• MVP is the leading

predisposing cardiovascular disorder in patients with endocarditis.

• Because the absolute incidence of endocarditis is extremely low in the entire MVP population, the risk of its developing in these patients has been a subject of considerable debate.

Thromboembolic Events

• Rarely, fibrin emboli may cause visual problems related to occlusion of the ophthalmic or posterior cerebral circulation.

• Patients younger than 45 years who have MVP are at greater risk for cerebrovascular accidents than would be expected in similar patients without MVP.

• Therefore, it has been recommended that antiplatelet drugs such as aspirin or anticoagulants be administered to patients with MVP who have a history of suspected cerebral emboli