Lec 1 Functional Areas of Cerebral Cortex

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    Brodmann numbered different areas of

    cerebral cortex. Based on function,

    2 types of areas:

    1) Sensory areas (located in post central gyrus,

    superior temporal gyrus & part of hippocampal

    gyrus & contain granular cortex)

    2) Motor areas (located in pre central gyrus & in

    other parts of frontal lobe & contain mainly

    agranular / pyramidal cortex)

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    1) ELECTRICAL STIMULATION OF DIFFERENT

    PARTS OF MOTOR AREAS : & movement of

    different parts of body is noted.2)ABLATION METHOD: A part of motor cortex is

    damaged & motor loss is noted.

    3) CLINICO-PATHOLOGICAL STUDY OF

    DISEASE: Post-mortem findings co-related toclinical loss of motor activity.

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    1) PRIMARY MOTOR AREA

    2) PRE MOTOR AREA

    3) SUPPLEMENTARY MOTOR AREA

    4) SPECIAL MOTOR AREAS

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    MOTOR AREAS Brodmanns no:

    Primary motor area 4

    Pre motor area 6

    Supplemental motor area 8, 9, 10

    Brocas area / Motor

    speech area

    44, 45

    Frontal eye field 8

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    LOCATION: Lies in first convolution of frontal

    lobes anterior to central sulcus. It begins

    laterally in the sylvian fissure, spreads

    superiorly to uppermost portion of brain & then

    dips deep into the longitudinal fissure. It is

    brodmanns area 4.

    It consists ofagranular type of cerebral cortex.In this area in layer no: 5, there are giant

    pyramidal cells called Betz cells

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    There is topographical (parts by parts)

    representation of body & contralateral as well

    as upside down representation. By joining

    these parts, a figure of the body is formed:

    MOTOR HOMUNCULUS. It is a mirror image

    ofSENSORY HOMUNCULUS.

    Parts of body concerned with precise, fine &skilled movements, are represented by

    much larger area.

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    Coordinated movement of contra-lateral

    parts of body.

    Blood flow to motor cortex varies withmotor activity of different parts of body,

    e.g, if right hand is moved, blood flow to

    hand representation area in left motorcortex is increased (because ofcontra-

    lateral control)

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    AFFERENT CONNECTIONS:

    Receives afferents from primary motor area ofopposite side &

    Afferents from premotor & supplementarymotor areas &

    Afferents from somatic sensory, auditory &

    visual areas & Afferents from thalamus, basal ganglia &

    cerebellum.

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    EFFERENT CONNECTIONS:

    Efferents to spinal cord as corticospinal tract.

    Efferents to cranial nerve nuclei (corticobulbarfibers).

    Efferents to thalamus.

    Efferents to basal ganglia.

    Efferents to cerebellum as cortico-ponto-

    cerebellar fibers.

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    LOCATION:Anterior to primary motor

    area. It extends 1-3 cm anteriorly.

    It is broad at top & narrow below.

    At the top it extends upto longitudinal

    fissure & below upto sylvian fissure /

    lateral fissure.

    It consists of superior, middle & inferior

    frontal gyri. It is brodmanns area 6.

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    In this area there is also topographical representation of

    different parts of body & pattern is similar to that inprimary motor area.

    When pre motor area is stimulated there aremovements involving contraction of groups of muscle.

    This area is connected with primary motor area, directlyor indirectly through basal ganglia & then throughthalamus.

    This area programs the activity of primary motor areawith the help of patterns already stored in brain.

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    LOCATION: Lies mainly in the longitudinal fissure but

    extends a few centimeters onto superior

    frontal cortex. It contains medial frontal gyrus.

    In this area different parts of body are

    also represented. Face is anterior, legs are posterior, back

    is in superior wall of singulate sulcus.

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    When this area is stimulated, movement oflimbs or other parts on both sides (bilateral

    movement).

    Bilateral grasping movement.

    This area controls the attitudinal, positional orfixation movements, e.g, background posturerequired for climbing up.

    It supplements finer motor control areas (premotor & primary motor) by positionalmovements of head, eyes etc.

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    LOCATION: In inferior frontal gyrus, justanterior to face representation area in primary

    motor cortex.

    It is brodmanns area 44, 45.

    It is just above latral sulcus / sylvian fissure.

    In this area detailed motor pattern for

    contraction of muscles of phonation &

    articulation is formed

    .

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    Then impulses are sent from this area toprimary motor area to initiate these

    contractions. This area recieves impulses from

    Wernickes area through arcuatefasiculus.

    Spoken speech parts:

    1) Phonation (to initiate vocal cord

    vibration, these must be adducted)

    2)Articulation

    3) Resonance

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    MOTOR APHASIA: Difficulty in utteringwords & speech is limited to only few

    words.

    Also called NON-FLUENT APHASIA. Damage does not prevent vocalizing.

    May utter a simple word such as no or

    yes. Impossible to speak whole words.

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    LOCATION: In the pre motor area immediately aboveBrocas area is a locus for controlling voluntary eyemovements.

    It is brodmanns area 8.

    When this area is electrically stimulated, there is

    conjugate deviation of eyes towards opposite side.

    Similar area is also present in occipital lobe.

    Frontal eye field also controls eye-lid movements likeblinking. When this area is damaged, person cannotmove eyes from one object to other.

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    3) HEAD ROTATION AREA:

    Near frontal eye field, slightly higher in motorassociation area.

    Controls rotation of head. Electrical stimulation elicits head rotation

    It directs the head towards different objects.

    4)AREA FOR HAND SKILLS: In the premotor area, immediately anterior to primary

    motor cortex for hands & fingers.

    Controls hand skills.

    When this area is damaged by tumors or otherlesionsMOTOR APRAXIA. Hand movementsbecome uncoordinated & non-purposeful.

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    BROCAS

    AREA

    PRIMARY MOTOR

    W. Area

    CORTEX

    ADDUCTORS

    OF

    VOCAL

    CORDS

    PHONATION

    Pattern impulses

    Allows to contract

    ARCUATE

    FASICULUS