JOINT RELIEF: Synergistic Joint Complex

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Product Data Sheet KEY FEATURES • Synergistic Joint Complex† • Supports Joint Health† KEY MESSAGES • Scientifically designed to bring safe and effective relief to sore and overworked joints.† • Max Joint Relief contains the precise amount of Glucosamine and Chondroitin based on the study done at Boston University School of Medicine.† • Includes ingredients that have been shown to be very effective in the treatment of joint problems related to inflamed and sore arthritic joints.† • Additionally contains MSM, Tumeric and Ginger which have been shown to have an anti-inflammatory affect on joints.† TARGET MARKET Primary: Anyone who suffers from joint pain and inflamma- tion. Secondary: Athletes that create additional stress on joints due to intense training. RECOMMENDED STACK • Max Vit-Acell • Max Complete Advanced Joint Support Formula Max Joint Relief was designed to bring safe and effective relief to sore and overworked joints. The synergistic effects of the ingredients in this proprietary formula have been proven in university studies to bring safe and effective relief to arthritic and sore joints. Researchers from the Center at the Boston University School of Medicine showed that glucosamine sulfate and chondroitin sulfate were very effective in the treatment of joint problems related to inflamed and sore arthritic joints. Glucosamine Sulfate plays a key role in the maintenance and repair of joints by stimulating cartilage cells to produce glycosaminoglycans and proteo- glycans, the building blocks of cartilage. The university study mentioned above used a specific ratio of Glucosamine and Chondroitin. In this study it was shown that an effective higher end oral dose was 1500mg of Glucosamine Sulfate and 1200mg of Chondroitin Sulfate. Max Joint Relief was formulated to the exact specifications of the study. Chondroitin sulfate provides the raw materials of the cartilage found in the joint. Research studies have shown that chondroitin sulfate can be a very effective treatment for arthritis pain and joint problems by inhibiting free radicals that degrade joint cartilage and collagen and improving blood circulation to joints which enables antioxidants and glucosamine to enter inflamed joints to stimulate the repair process required for the regression of osteoarthritis. MSM (methylsulf- onylmethane) is a bio-available form of dietary sulfur, and is a naturally occurring compound found in significant amounts in nerve and connective tissue, skin, hair and joints. Supplementing with MSM can help support the development of new cells and connective tissue, and may been linked to promoting healthy muscles, ligaments and flexible joints. As we age our MSM levels decline, increasing the need for supplementation. MSM also helps provide temporary relief from pain and inflammation. Ginger(Zingiber officinale) has been used for thousands of years for medicinal purposes, such as nausea, stomach ache, rheumatism and toothache. Modern research has found ginger to be a powerful antioxidant with anti-inflammatory benefits. The active components of ginger are thought to be aromatic ketones known as gingerols. These have been shown in experimental studies to inhibit both the cyclooxygenase and lipoxygenase pathways and the production of prostaglandins, thromboxane and leukotrienes, just as the NSAIDs do. Studies have compared Ginger to ibuprofen as an anti-inflammatory agent, without the associated side effects. Turmeric (Curcuma longa) is a member of the ginger family and has long been used a powerful healing herb. In the early 1970's researchers discovered that it contained notable inflammation-fighting compounds (cont’d on p.2) Size: 120 Capsules Serving Size: Four (4) Capsules Servings Per Container: Approx. 30 210 W. Taft Ave.• Orange, California 92865• 714.456.0700• 714.456.0727 fax Your assurance of quality ® www.maxmuscle.com SYNERGISTIC JOINT COMPLEX

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Max Joint Relief was designed to bring safe and effective relief to sore and overworked joints. The synergistic effects of the ingredients in this proprietary formula have been proven in university studies to bring safe and effective relief to arthritic and sore joints. Researchers from the Center at the Boston University School of Medicine showed that glucosamine sulfate and chondroitin sulfate were very effective in the treatment of joint problems related to inflamed and sore arthritic joints. [Read more]

Transcript of JOINT RELIEF: Synergistic Joint Complex

Product Data Sheet

KEY FEATURES• Synergistic Joint Complex† • Supports Joint Health†

KEY MESSAGES• Scientifically designed to bring safe and effective relief to

sore and overworked joints.†

• Max Joint Relief contains the precise amount of Glucosamine and Chondroitin based on the study done at Boston University School of Medicine.†

• Includes ingredients that have been shown to be very effective in the treatment of joint problems related to inflamed and sore arthritic joints.†

• Additionally contains MSM, Tumeric and Ginger which have been shown to have an anti-inflammatory affect on joints.†

TARGET MARKETPrimary: Anyone who suffers from joint pain and inflamma-tion.Secondary: Athletes that create additional stress on joints due to intense training.

RECOMMENDED STACK• Max Vit-Acell • Max Complete

Advanced Joint Support Formula†

Max Joint Relief was designed to bring safe and effective relief to sore and overworked joints. The synergistic effects of the ingredients in this proprietary formula have been proven in university studies to bring safe and effective relief to arthritic and sore joints. Researchers from the Center at the Boston University School of Medicine showed that glucosamine sulfate and chondroitin sulfate were very effective in the treatment of joint problems related to inflamed and sore arthritic joints. Glucosamine Sulfate plays a key role in the maintenance and repair of joints by stimulating cartilage cells to produce glycosaminoglycans and proteo-glycans, the building blocks of cartilage. The university study mentioned above used a specific ratio of Glucosamine and Chondroitin. In this study it was shown that an effective higher end oral dose was 1500mg of Glucosamine Sulfate and 1200mg of Chondroitin Sulfate. Max Joint Relief was formulated to the exact specifications of the study. Chondroitin sulfate provides the raw materials of the cartilage found in the joint. Research studies have shown that chondroitin sulfate can be a very effective treatment for arthritis pain and joint problems by inhibiting free radicals that degrade joint cartilage and collagen and improving blood circulation to joints which enables antioxidants and glucosamine to enter inflamed joints to stimulate the repair process required for the regression of osteoarthritis. MSM (methylsulf-onylmethane) is a bio-available form of dietary sulfur, and is a naturally occurring compound found in significant amounts in nerve and connective tissue, skin, hair and joints. Supplementing with MSM can help support the development of new cells and connective tissue, and may been linked to promoting healthy muscles, ligaments and flexible joints. As we age our MSM levels decline, increasing the need for supplementation. MSM also helps provide temporary relief from pain and inflammation. Ginger(Zingiber officinale) has been used for thousands of years for medicinal purposes, such as nausea, stomach ache, rheumatism and toothache. Modern research has found ginger to be a powerful antioxidant with anti-inflammatory benefits. The active components of ginger are thought to be aromatic ketones known as gingerols. These have been shown in experimental studies to inhibit both the cyclooxygenase and lipoxygenase pathways and the production of prostaglandins, thromboxane and leukotrienes, just as the NSAIDs do. Studies have compared Ginger to ibuprofen as an anti-inflammatory agent, without the associated side effects. Turmeric (Curcuma longa) is a member of the ginger family and has long been used a powerful healing herb. In the early 1970's researchers discovered that it contained notable inflammation-fighting compounds

(cont’d on p.2)

Size: 120 Capsules Serving Size: Four (4) CapsulesServings Per Container: Approx. 30

210 W. Taft Ave. • Orange, California 92865 • 714.456.0700 • 714.456.0727 fax

Your assurance of quality®

www.maxmuscle.com

SYNERGISTIC JOINT COMPLEX

Product Data Sheet P.2

Directions: As a dietary supplement take four (4) capsules at once, in the morning with a meal or two (2) capsules twice daily with meals.

Other Ingredients: Rice Powder, Magnesium Stearate, Gelatin.

SHELL FISH ALLERGY ALERT – SEE WARNING STATEMENT

WARNING: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18 YEARS. DO NOT USE IF PREGNANT OR NURSING. Consult a Physician before using this product if you have, or have a family history of, including but not limited to arthritis, diabetes, and shell fish allergy. Consult your doctor if you are taking prescription medications. Drink at least 2 liters of water daily when using this product.

KEEP OUT OF REACH OF CHILDREN.

STORE IN A COOL, DRY PLACE AWAY FROM MOISTURE AND SUNLIGHT. ALWAYS KEEP TIGHTLY SEALED.

Does not contain: Yeast, corn, wheat, soy, gluten, milk, salt, sugar, starch, preservatives or artificial color.

ALLERGY INFORMATION: Contains Glucosamine Sulfate (derived from crustacean shellfish) and Chondroitin Sulfate (derived from bovine). Manufactured in a facility that processes milk, soy and egg proteins, fish and shellfish, peanuts and other tree nuts and wheat.

Size: 120 Capsules Serving Size: Four (4) CapsulesServings Per Container: Approx. 30

To report a serious adverse event, contact:Max Muscle Sports Nutrition

210 W. Taft Ave., Orange CA 92865www.maxmuscle.com

SYNERGISTIC JOINT COMPLEX

(cont’d from p.1)

called curcuminoids. The anti-inflammatory compounds in turmeric appear to ease inflammation by inhibiting the COX- 2 enzyme, which is associated with inflammation. Turmeric has properties that resemble those of the COX-2 inhibitors–popular new arthritis drugs, such as Celebrex, that have been dubbed "superaspirins."

As with all the products in the Max Muscle line of supplements, Max Joint Relief has been formulated to give our customers the best possible results. We used the precise amounts of the ingredients used in key studies. Because of this we are confident that this product will deliver optimal results.†

Supplement FactsServing Size: Four (4) Capsules Servings Per Container: 30

Amount Per Serving % DV*Glucosamine Sulfate (crab, shrimp) 1.5g **Chondroitin Sulfate (bovine) 1.2g **Methylsulfonylmethane (MSM) 500mg **Ginger (Zingiber officinale) 100mg **Turmeric (Curcuma longa) 100mg **

*Percent Daily Values are based on a 2000 calorie diet.**Daily value not established.

Key References1. Murray RK, Keeley FW. The Extracellular Matrix. 27th ed. In: Murray RK, Granner DK, Rodwell VW eds. Harper’s Illustrated

Biochemistry. New York, NY: Lange Medical Books/McGraw-Hill 2006:545-64.

2. Black C, Clar C, Henderson R, et al. The clinical effectiveness of glucosamine and chondroitin supplements in slowing or arresting progression of osteoarthritis of the knee: a systematic review and economic evaluation. Health Technol Assess. 2009;13:1-148.

3. Bruyere O, Reginster JY. Glucosamine and chondroitin sulfate as therapeutic agents for knee and hip osteoarthritis. Drugs Aging. 2007;24:573-80.

4. McAlindon TE, LaValley MP, Gulin JP, Felson DT. Glucosamine and chondroitin for treatment of osteoarthritis: a systematic quality assessment and meta-analysis. JAMA. 2000;283:1469-75.

5. Usha PR, Naidu MU. Randomised, Double-Blind, Parallel, Placebo-Controlled Study of Oral Glucosamine, Methylsulfonylmethane and Their Combination in Osteoarthritis. Clin Drug Investig. 2004;24:353-63.

6. Varghese S, Theprungsirikul P, Sahani S, et al. Glucosamine modulates chondrocyte proliferation, matrix synthesis, and gene expression. Osteoarthritis Cartilage. 2007;15:59-68.

7. Bruyere O, Reginster JY. Glucosamine and chondroitin sulfate as therapeutic agents for knee and hip osteoarthritis. Drugs Aging. 2007;24:573-80.

8. Uebelhart D. Clinical review of chondroitin sulfate in osteoarthritis. Osteoarthritis Cartilage. 2008;16 Suppl 3:S19-21.

9. Kim, LS, Axelrod LJ, Howard P, et al. Efficacy of methylsulfonylmethane (MSM) in osteoarthritis pain of the knee: a pilot clinical trial. Osteoarthritis Cartilage. 2006;14:286-94.

10. Van Breemen RB, Tao Y, Li W. Cyclooxygenase-2inhibitors in ginger (Zingiber officinale). Fitoterapia. 2010 Sep 15.

11. Grzanna R, Lindmark L, Frondoza CG. Ginger—an herbal medicinal product with broad anti-inflammatory actions. J Med Food. 2005;8:125-32.

12. Rao CV. Regulation of COX and LOX by curcumin. Adv Exp Med Biol. 2007;595-26.

13. Menon VP, Sudheer AR. Antioxidant and anti-inflammatory properties of curcumin. Adv Exp Med Biol. 2007;595:105-25.