JDRF - 2012 Annual Report · 2014. 4. 2. · Our 2012 Annual Report is a celebration of JDRF’s...
Transcript of JDRF - 2012 Annual Report · 2014. 4. 2. · Our 2012 Annual Report is a celebration of JDRF’s...
42 YEARS. 42 REASONS.
2012 Annual Report (Essentials)
Please visit jdrf.org/2012annualreport
to view the entire Annual Report online.
Table of Contents
CEO Message ...........................................................3
JDRF Supporters ....................................................5
Financials ................................................................24
Leadership ..............................................................25
About JDRF
JDRF is the leading global organization focused on type 1 diabetes (T1D) research. Type 1 diabetes is an autoimmune disease that strikes both children and adults. Unrelated to diet or lifestyle, T1D causes lifelong dependence on injected or pumped insulin and carries the constant danger of life-threatening complications. It requires intensive, 24/7 management. There are no days off, and there is no cure.
Parents founded JDRF in 1970 to help their children with T1D by funding research to find a cure for this poorly understood and often deadly disease. Driven by passionate, grassroots volunteers connected to children, adolescents, and adults with this disease, JDRF has grown to become the largest nongovernmental funder of T1D research. JDRF has awarded more than $1.7 billion to diabetes research since our founding.
Our goal is simple: we want to create a world without T1D. JDRF is the only global organization with a strategic plan to bring a continuous stream of life-changing therapies, and ultimately, a cure for T1D.
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to view the entire Annual Report online.
Our 2012 Annual Report is a celebration of JDRF’s 42nd year highlighting many of the amazing supporters and initiatives that make us the global leader in T1D funding we are today. The progress we have made in 42 years is tremendous and our vision for the future has never been clearer or stronger: a world without T1D.
In this world:
• Children with T1D and their parents sleep through the night without fear
• An intelligent pump eliminates dangerous high and low blood-sugar levels
• A single daily insulin injection maintains tight control with no carb counting
• Developing T1D is no longer a concern for you or your loved ones
• There is no carb counting, no injections, no testing...no T1D
JDRF isn’t just imagining this future. We’re making it happen. JDRF is the only global organization with a strategic plan to bring a continuous flow of life-changing therapies and, ultimately, a cure for T1D. Our past investments have yielded significant advances.
They have also taught us that there will likely be no single “eureka” moment that will cause T1D to vanish all at once. Instead, we know that progress towards a cure will be a series of breakthroughs across different therapeutic approaches occurring on different timelines. JDRF’s strategic plan for research funding will ensure there is an ongoing stream of programs underway to develop and commercialize therapies that lessen the impact of T1D—
keeping patients healthy and safe until our vision is achieved.
We’re delivering a sustained stream of new, life-changing therapies. Underlying JDRF’s strategy is our work to optimize funding across the translational research
continuum—from early stage development through delivery to patients. The most strategic allocation of resources should create improvements that will deliver relatively near-term meaningful clinical impact, as well as ensure there is active academic and industry engagement in early stages of the pipeline necessary to support subsequent generations of therapeutic interventions.
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“I believe that one day in the future, we will declare victory and eliminate type 1 diabetes entirely—and JDRF will have led the way.”
CEO Message
A Vision for the Future
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By driving investment across the pipeline, we envision a cascade of progress that will occur over the next 20 years. While we cannot predict exactly what the future holds, given the JDRF-funded research underway today this progress is likely to include:
• Progressive elimination of blood-glucose testing and automation of insulin delivery through a series of artificial pancreas systems currently in clinical trials;
• Ability to identify those most at risk for developing complications of T1D;
• An implantable, islet cell replacement therapy that can restore insulin independence and eliminate the need for immune suppression;
• Glucose responsive insulin that supports a single shot of insulin per day or week;
• The body’s ability to regenerate islets to restore normal glucose control while preventing the re-attack of the immune system;
• Secondary prevention therapies that slow or halt the progression of T1D before insulin dependence; and
• Primary prevention through universal childhood immunization.
We’re uniquely positioned to create a future without T1D.
Driving this ambitious research progress will require substantial annual investments to reach our goal of living in a time when T1D is spoken about in the past tense. We know the path forward is expensive and will take more than the $530 million JDRF has at work around the globe today advancing our goals. The gap between what we have and
what we need is significant. We’re doing all we can to bridge that gap, but we need your help. Your continued support will help change the pace of T1D advancements, accelerating progress down the path to improving lives and curing T1D.
Please join us in creating this future by giving to JDRF today. T1D doesn’t wait—and neither can JDRF.
Thank you for all that you do for JDRF.
Jeffrey Brewer
President and Chief Executive Officer
Please visit jdrf.org/2012annualreport
to view the entire Annual Report online.
FISCAL YEAR 2012
JDRF Supporters
JDRF is the global leader in funding T1D research because of the continued support of our devoted donors. Every dollar we spend on research comes from you. Thank you for helping JDRF to bring life-changing therapies and, one day, a cure for T1D.
JDRF Walk to Cure Diabetes ........................................6
Gala .........................................................................................7
Corporate Partners ...........................................................8
Major Donors and Partners ............................................9
BETA Society Members ................................................. 21
Stem Cell Research Fund ............................................ 22
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to view the entire Annual Report online.
FISCAL YEAR 2012
JDRF Walk to Cure Diabetes
The JDRF Walk to Cure Diabetes Program thanks all of our passionate and dedicated families, volunteers, local businesses, and corporations. Your support of the Walk is essential to JDRF’s fundraising strength and global growth.
We also express our deepest gratitude to our many corporate partners for their commitment and support of the JDRF Walk to Cure Diabetes, both nationally and internationally. We extend a special thank-you to our national Walk partners: Advance Auto Parts, Ford Motor Company, Marshalls, Hy-Vee, Inc., Roche, and Walgreens.
Cohn Sisters: Mackenzie’s MM and
Sydney’s SuperStars
Eastern PA/Delaware Chapter
Tessa’s Troopers
Los Angeles Chapter
Michael’s Legal Eagles/Kiwanis
New York Chapter
Charlie’s Angels
Los Angeles Chapter
Schuyler’s Cute Cupcakes
New York Chapter
Punkin’s Peeps
New York Chapter
Mimi’s Marchers
Long Island Chapter
Harmelin Family Team
Eastern PA/Delaware Chapter
Congratulations to the FY2012 family Walk teams that raised $75,000 or more!
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FISCAL YEAR 2012
Gala
We are pleased to recognize below the Honorees who helped lead their chapters in raising more than
$100,000 through the 2012 Gala Program. Thank you to all the guests, supporters, and volunteers who
make each JDRF Gala so successful and inspirational.
Patrick and Shauna McFeeley Greater Western Carolinas Chapter
Jerzy GruhnNovo NordiskEastern PA/Delaware Chapter
John J. McDonough Florida Suncoast Chapter
Dr. Bruce BodeGeorgia Chapter
Genentech, Inc.Greater Bay Area Chapter
Anheuser-Busch CompaniesGreater Missouri & Southern Illinois Chapter
Mr. and Mrs. Stephen P. Sparkman IICasey Auto GroupHampton Roads Chapter
John J. McDonoughIllinois Chapter
Michael Alter, Karen Case, Marci Eisenstein and John Treece, and Glen Tullman Illinois Chapter
Leanne DeShongShook, Hardy & Bacon LLPKansas City Chapter
David and Wendy NovakYum! Brands, Inc.Kentucky Chapter
Shelby Notkin, Michelle Notkin Rosen, and Zach RosenDr. Kevin KaisermanLinda Wallem, Stephen Wallem, and Showtime’s Nurse JackieLos Angeles Chapter
Ron ShapiroShapiro Negotiations InstituteMaryland Chapter
Wade and Susan KotulaNorthern Tool + EquipmentMinnDakotas Chapter
Bill HornbuckleMGM Resorts InternationalNevada Chapter
Leslie and Michael WeintraubNew England Chapter—Bay State Branch
Liam McGeeThe HartfordNorth Central CT & Western MA Chapter
Barrick Gold North America and Newmont Mining CorporationNorthern Nevada Branch
Linda TharbyBD MedicalThe Byrne FamilyNorthern NJ–Rockland County Chapter
The Terry Gallagher FamilyRocky Mountain Chapter
Dr. Mitchell Eisenberg Sheridan HealthcareSouth Florida Chapter
The Braswell FamilyTriangle/Eastern North Carolina Chapter
Arlo and Barbara DeKraaiHille FoundationGary and Anita RathburnOklahoma/Northwest Arkansas Chapter—Tulsa Green Country Branch
Highmark Inc.Western Pennsylvania Chapter
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FISCAL YEAR 2012
Corporate Partners
Elite Principal Partners$2 million-plus annual givingAdvance Auto PartsFord Motor CompanyMarshalls
Principal Partners$1 million-plus annual givingHy-Vee, Inc.RocheWalgreens
JDRF 2012 Annual Conference Award Recipients
Rising Star Award:Cash America International, Inc.
Director’s Award:Discover
President’s Award:Wawa
Chairman’s Award:Walgreens
Pinnacle Award:Lilly Diabetes
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FISCAL YEAR 2012
Major Donors and Partners
$3,000,000+Advance Auto Parts Ford Motor Company
$1,000,000 – $2,999,999Hy-Vee, Inc. Estate of Eleanor A. Leatherby MarshallsRocheWalgreens Yum! Brands Foundation
$500,000 – $999,999Bloomingdale’s, Inc. Henry D’AuriaEstate of Roberta DenehyStop & ShopTops Markets, LLCWawa
$250,000 – $499,999AnonymousAbbottAllscriptsCasey’s General Stores, Inc.Cash America International, Inc.DiscoverThe Dove Family FoundationGoDaddy.comLilly DiabetesMedtronicNordstromNovo NordiskEstate of Patricia PykaryAnita and Gary RathburnThe O. Wayne Rollins FoundationThe Scaramucci FamilyThe Fresh MarketEstate of Lewis L. TollTommy HilfigerTurner Broadcasting System, Inc.The Agnes Varis TrustLisa and Neil WallackEstate of Norbert J. Wrobel
$100,000 – $249,999Anonymous (6)Diane AdamsKen AldridgeJames B. and Lois R. Archer
FoundationFrederick Banting FoundationBB & TThe Bruce Bergman Family
Charitable FundBoston Marriott Copley PlaceBuild-A-Bear Workshop® FoundationCapitol One Services, LLCBill and Kim ChisholmTara CocoEstate of Phyllis CohenThe Cohn Family FoundationCommunity Health Charities
of NebraskaThe Cooper-Siegel Family FoundationThe Dream Fund at UCLAEstates of Harold L. Dwyer
and Nevada W. DwyerEnglestad Family FoundationEricsson, Inc.Mr. and Mrs. Larry FranklinThe James A. Gammon Charitable
FoundationGenentech, Inc.The Horace W. Goldsmith FoundationEstate of Steven B. GrantMichelle Griffin and Tom ParkerHalloween Adventure and Smart ToysPatty and Chip HalversonWilliam B. and Kimberly E. HayesH-E-BHess CorporationHillcrest Foundation, founded by
Mrs. W.W. Caruth Sr.Jensen Charitable Lead Annuity TrustRon Jensen Charitable Lead
Annuity TrustBetty Wold JohnsonCharles and Ann JohnsonHerbert and Karen Lotman
Estate of Joan E. LuikingJudge Richard and Carol MarkusEstate of Michael J. McBeeMarilyn and John McDonoughMoe’s Southwest Grill Harry S. Moss Charitable TrustNationwide Insurance FoundationDaryl and David NelmsNicholson Partners LtdShelby Notkin and Darcie Denkert
NotkinDavid and Wendy NovakOffice PavilionOneSight Research FoundationPella CorporationThe George Polli Memorial Golf
Outing—benefitting JDRFKay and Jay ProopsMitchell and Nina QuarantaJoAnn and Chuck QueenanQuick Chek Food StoresDr. George and Mrs. Kym RapierEstates of Barbara H. and
George F. RavenLars and Joanne ReiersonRepublic FinanceRussell Stover Candies, Inc. The Gary Saltz Foundation, Inc.Susan and Sheldon SandlerEstate of Tremayne SeligShort Family Charitable FundSilpada Designs, LLCSnyder’s-Lance, Inc. Sonora Quest LabsThe Sorenson Legacy FoundationSuper AmericaEstate of Ronald SwidlerTesoroTETCO Texas InstrumentsTrish and Glen TullmanUSA Drug Mrs. Vivian VanceWal-Mart FoundationWells Fargo
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$75,000 – $99,999AnonymousAldridge Electric, Inc.Lisa and Steve AltmanAssociation of Contracting Plumbers of
the City of New York, Inc.Bridget and Mike BenderBlackbird TechnologiesRose and Michael BoyleMr. and Mrs. Alan FisherWindy and Terry Gallagher Jr.
and FamilyGordmansHurlbut-Johnson Charitable Trusts,
an advised fund of the Silicon Valley Community Foundation
Jenny JohnsonMargaret L. Kenyon TrustBen LeedsJun and Uzal MartzStuart and Flora Mason and
the Mason FamilyPatrick and Shauna McFeeleyMead FoundationMicrosoft CorporationBeth and Barry MitchellOld Orchard Brands, LLCParty CityEstate of William Vinson
$50,000 – $74,999Anonymous (3)AAR Corp.Abby’s FriendsActivisionMary and Dick AllenMr. and Mrs. Neal AllenEstate of Helene Alley in memory of
Theodore Whitlock and Theodore Whitlock Jr.
Allstate Insurance CompanyAlpine Children’s CharityThe James Annenberg La Vea
Charitable FoundationAnthem Blue Cross and Blue Shield
FoundationAon CorporationHelene and Allen Apter FoundationEstate of Jeanne AvegnoBank of AmericaBank of the WestBD TechnologiesBecton, Dickinson and CompanyBerkot’s Super FoodsBoyle Family Foundation
Broadway Cares/Equity Fights Aids, Inc.
Mark, Valerie, and Jason BrodskyBuford Family FoundationBurrows Family FoundationThe Steven Burrows FamilyAmy and Matt CampbellChicago Cubs CharitiesElsie and Josephine Colombo
Charitable TrustBarbara and Arlo DeKraaiEd Miniat, Inc.Marci Eisenstein and John TreeceAndrew II and Jane EvansGilbert and Jacqueline R. Fern
FoundationJanet and Ken FollansbeeFranklin Templeton InvestmentsGila River Indian CommunityThe Stewart and Marlene Greenebaum
Family FoundationHagans Burdine Montgomery
& Rustay, P.C.In honor of Parker Hall—Carol Good,
Jay and Babs Rosenfeld, Malcolm and Donna Wheeler, LeMoyne and Dolores Hall, Garrett and Julie Hall, Malcolm and Pam White
The Stephen P. Hanson Family Foundation, Inc.
Harris TeeterThe HartfordHenry Schein, Inc.The David Herro Charitable FoundationKathy and Jim HippsEstate of D.H. HirsbergHope For A Cure GuildBill and Wendy HornbuckleRoger and Cathy HughesJack’s Family RestaurantJackson FoundationNancy and Donald Jones Jr.Mr. and Mrs. John KampfeElisabeth and Greg KimmelKnights of Pythias Diabetes Research
AssociationEstate of Lynda Lee KoopmanBarbara KourisMarisue and Joe LacherLand O’FrostErnest Lieblich FoundationLifeScan, a Johnson & Johnson
CompanyLund Food Holdings, Inc.The Tony and Renee Marlon Charitable
Foundation
Luther T. McCauley Charitable Trust Nalco CompanyBarbara and Thomas NealPepsiCoCathryn and Chris PerryMarjorie C. Phemister Charitable
Remainder UnitrustThe Mettita S. Pick FoundationPlaza Marketing Associates, Inc.Tom and Stella PressSusan and Walter PyeQualcomm IncorporatedMr. and Mrs. Donald ResnickLiberto Management/Ricos ProductsRoche Diagnostics Julie and Len RodmanRon Santo Golf ExperienceBill and Pam SaganSage Hospitality ResourcesMarlene and Bruce SaltzbergFred E. SieberSub-Zero FoundationMr. and Mrs. David A. SwansonTaco BellTempe Dodge, Chrysler, Jeep, Kia—
William KoloseikeUnited HealthcareUPSJohn and Whitney ValentineWalsh, Calucci, Lubeley, Emrich &
Walsh, P.C.Jane and Craig WehrliJohn and Margaret WhitlockEstate of Rafael Zeron in memory of
Manuela Zeron
$25,000 – $49,999Anonymous (7)432 Park Avenue South Realty
CompanyAmy and Micah AdamsADESAAffiliated Computer Services, Inc.Aimbridge HospitalityAlphanumeric SystemsSarah and Michael AlterAmerican Financial GroupAmes Construction, Inc.Amylin Pharmaceuticals, LLCThe Annenberg FoundationApollo Jets, Mark Hader, and
Al PalagoniaAnnabel Galva-Arthur and
Jason ArthurJohn and Rosalind AshkarAshland, Inc. Valvoline
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Elizabeth and Tom BahnBain Capital Children’s CharityBaker Hughes FoundationMr. and Mrs. Jack and Eleanor BarnesLynda and Chris BarnesBarrick GoldBashasBaylor Health Care SystemTroy and Cindy BeallMichael and Carolyn BealmearElizabeth Ann Beck FoundationBerge GroupBarbara Bishop-GollanBKD FoundationBlue Cross Blue Shield of GeorgiaBluegreen CorporationBNY Mellon Asset ServicingShannon and Richard BonnessPatrick and Darcy BowenBP AmericaKaren and Harvey BraswellMr. and Mrs. Clay BretchesAnastasia and Nicolas Brien The Brockriede FamilyMr. and Mrs. Dan BrooksC.H. Robinson, Inc.Cantor FitzgeraldRoy and Vanessa CarrollMary Kate and Robert CaryKaren and Jay CaseMr. and Mrs. Andrew CashShari and Robert Cashman/Metro
Credit UnionEstate of William CederholmCereal Food Processors, Inc.The Rhoda and David Chase Family
FoundationChevron CorporationChicago Title Commercial ServicesCisco Systems, Inc.CityCenterDC: A development by
Hines, Archstone, and the First Investor
Clark ConstructionCleary Gottlieb Steen & Hamilton, LLPCoca-Cola Refreshments Mr. and Mrs. Fielding CockeCoffee Bean & Tea Leaf and
Jamba Juice—Las VegasEstate of Samuel A. CohenBrett and Karen Coleman FoundationCommunity Health Charities of IllinoisWilliam R. Conley Jr.Karen and Brian CooperE.L. Cord FoundationMr. and Mrs. David and Sherry Cordani
Laura and Kelly CrainThe Crippled Children’s FoundationCrowder Construction CompanyMark CurryElinor M. Cuvelier TrustDanaher Tool GroupThe Darvin Family/Beachwood City
Schools/Darvin AmbulatorsDash to Cure Diabetes, Inc.DeMaris and Kenneth DavisDCP MidstreamDelta Air Lines, Inc.Leanne DeShong and James ConlonDeutsche BankMr. and Mrs. Matt DevineDobbs Tire & Auto CentersSuzy and Sean DohertyDr Pepper Snapple GroupHoffman Construction/Wayne and
Julie DrinkwardBarb and Bill DrotarDST Systems, Inc.DualiteMr. and Mrs. Norman EakerMary Ellen EdmondsPamela F. and Franklin S. Edmonds Jr.Ric and Brenda EliasEmkay, Inc.Kim and Peter EnnsEntergy Ernst & Young, LLPAnne EspositoBrady ExberExcelon CorporationRobyn and Brian FagenDavid and Marianna FisherFore-Ward for a CureMr. and Mrs. Rick ForshawHeidi and Rod FosterMelanie and Jeff FoxCarl M. Freeman FoundationChristopher and Jennifer FrenchEstate of Mary GalepRobert E. Gallagher Charitable TrustKatheryn and Robert GardnerTed and Lisa Gardner and FamilyGEICOKaren and Tom GentryPatrick Hall on behalf of Glen Cove PBAEstate of Jeremy GoetzGold Metal Recyclers, Ltd.Goldberg Kohn, Ltd.Good Times Burgers &
Frozen CustardMichael and Loren GordenBecky and Brett Gordon
Elisa and Greg GraceffoGrant ThorntonNancy and Donald GrayKaren and Sam GrecoGreenacre Properties, Inc.Jonathan and Stefanie GreenbergCricket GriffinGuilford FoundationMr. and Mrs. W. Fred HagansErick and Barb HallickHanesbrands, Inc.Nedra and Donald Hansen Sr.Randie and Robert HarmelinMs. Virginia M. HartleyBernhard J. Hering, M.D., and
Nicole Kirchhof, DVMConrad B. HerrmannThe Hershey CompanyHess Foundation, Inc.Hoffman Car Wash and
Hoffman Jiffy LubeGisela and Dan HoodHorizon PaperDeborah HuntingtonIllinois Tool WorksFrank Ingrassia and Elizabeth McCaulIntriCon CorporationJansen Family FoundationStacey and Dave JohnsonDr. Steven and Angie JohnsonMirko and Elizabeth JokanovicBrighton JonesEdward JonesCol. Gary and Christine JonesJeff and Karen JordanKaiser Permanente Golf Event to Fight
Diabetes Jackie and Norm KallanMrs. Sheri Frazier-Kesner and
Gerald KesnerBrent Kessel and Britta BushnellKindred HealthcareMr. Maury KlumokMary and Phil KnellKoch FoundationMr. William KoloseikeThe Komar Family Estate of Sharon G. KoppMr. and Mrs. Doug KoskieSteve and Marilyn KraftMary and Jeff KrivitKroger Co.Kenneth and Jennifer KronerLabCorpHerbert and Sharon LampertMary Ann Larkin and Carol Stillwell
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Brad and Vickie LarsenJeannie and Jonathan LavineHelene and Jim LawrenceLazlo’sLeatherby Family FoundationJoann Leatherby and Dr. Greg BatesDr. Ken and Renee LegaultLaurence W. Levine FoundationThe Lincoln Electric CompanyLiner Grode Stein Yankelevitz Sunshine
Regenstreif & Taylor, LLPLiUNA GEB and MembersLeon Lowenstein Foundation, Inc.Marguerite and James MahanAmir and Rosita Manocherian Family
FoundationMariner Wealth AdvisorsTimothy MartinMargaret and David MasseyMaxon Precision Motors, Inc.The Garage—Team MazdaTracey and Josh McCarterEstate of Anna McCormickMr. and Mrs. James McDonaldMr. and Mrs. Liam and Lori McGeePhyllis McGovernAmanda and Marc McIntyreMcMichael Family FoundationMercedes-Benz of GreenwichStanley MeyersThe Alan B. Miller Family FoundationPeggy and Gene MillerLisa and David MiniatPauline and Ronald MiniatAmy and Joseph MogliaAlan Morris and Pia Exber-MorrisMyCare ConnectJames and Sally Nation FoundationMeeghan and Michael NemeroffNewmont Mining CorporationNorris FoundationJean Norris and Vince NortonOmaha SteaksDavid and Joan O’ReillyCarla and Mark PalmoreParker Hannifin CorporationPCB PiezotronicsMr. and Mrs. Dave PeacockPerot FoundationJeff PetroPhillips Plastics CorporationPiccadilly Restaurants, LLCPIMCO FoundationDena and Michael PlumerLaurence Polatsch Memorial FundMelinda and Rick Poulton
PricewaterhouseCoopers, LLPPrivate Trade Winds, Inc.Lisa and Marc PrydeBarbara and Ronald RapaportIra Leon RennertREO World, Inc.Mr. and Mrs. Brian RichCecilia and Thomas RickettsMarlene RickettsEstates of James W. and
Lee Gardner RoachLisenne Rockefeller and FamilyHarriet RossNancy, Jennifer, and Kimberly RossSaipem AmericaSanford HealthJim and Beth SankeySARCOMSteve and Jenny SavitskyMarge and Bob SchaferSchiff Hardin, LLPSchlumbergerMichael and Faith SchoenfeldMr. and Mrs. Thomas Schwartz Sequent Energy ManagementShell LubricantsShook, Hardy & Bacon, LLPScott and Stefanie SibleySiemensMr. and Mrs. Morton Silver Ms. Sydney SimonsSimply FashionsKP SinghEstate of Rose SipoczSkinny Nutritional Corp.Smoker FriendlyJeanette and Seymour Spira Donor
Advised Fund Endowment of the Jewish Federation of Northern New Jersey
Anne and Bernard SpitzerThe Stargatt FamilyStarnet Data Design, Inc. Toby and Michael Rozen/Joseph F.
Stein Family Foundation, Inc.Luke and Scotti StrockisDebora and Michael SullivanLisa and Brian SullivanMs. Lanette SuttlesKris and Greg SwetnamThe Taft FoundationMr. and Mrs. Andrew TaylorTennecoTexas Cavaliers Charitable FoundationMr. and Mrs. James TheissThe Thomas Foundation
William and Helen Thomas Charitable Trust
Joan and Byron ThompsonKay and Don ThorpThe TJX Foundation, Inc.Touchstone Communities, Inc.Travelers InsuranceTRICO ProductsBonnie Trotta Glen TullmanPatricia and Glen TullmanUnileverMr. and Mrs. Richard UnnerstallUS BankValero Energy FoundationMr. and Mrs. Jeff VanceVanderbilt University Medical CenterVolkswagen Group of America, Inc. David and Judy WachsWake Forest Baptist HealthThe Walbridge Fund, Ltd.Marlene and Larry WaldKevin and Erin WehrenbergGary and Tari WeissJeffrey WestphalJim and Lori WhiteMr. and Mrs. Hans WiemannMr. and Mrs. James Winchester Jr.Estate of Jo-Ann L. WinnThe Woodbury FoundationRichard S. WorthingtonMr. and Mrs. Larry WrightFrances YedlinMonica and Robert YollesZaring Family Foundation
$10,000 – $24,999Anonymous (16)AARP Services, Inc.Mr. and Mrs. David AbesDr. and Mrs. Marshall AbesAbrahamson Family FoundationKenneth A. Abrams Charitable
FoundationLisa and Michael AbsatzAbsolute Pharmacy, Inc./Avalon
Foodservice, Inc.Active InternationalJeff and Wendy AdamsAdvance Benefit AdvisorsAdvanced BioHealingAdvanced Ground Systems
Engineering, LLCAetna Foundation, Inc.AFLACAkebono
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Akin Gump Strauss Hauer & Feld, LLPAkron Children’s HospitalAlamance Regional Medical CenterKathy AlbertDiane and Bruce AllenMichael AllenAlliance Bank of ArizonaAllianceBernsteinThe Allstate FoundationAltec Industries and Altec Styslinger
FoundationThe Jeffrey A. Altman FoundationAMC TVAmegy BankAmerican AirlinesAmerican Direct Marketing
Resources, Inc.American ExpressAmerican General Life and Accident
Insurance Company (AGLA)Ameritas Life Insurance Corp.Ametek Foundation Mr. and Mrs. Mohammad AminiAnadarko Petroleum CorporationDon and Betty AndersonMD Anderson Foundation Melonia and Randy AndersonMr. and Mrs. George AndrewsMr. and Mrs. Greg AndrewsAndrie Trading, LLCRobert AngelAnimas CorporationAOL AdvertisingApacheAPI Heat TransferApollo Health Street, Inc.Arkansas Blue Cross and Blue ShieldArmstrong Teasdale, LLPMr. and Mrs. Jeff ArnoldArrow Finance CompanyArvato Print, BertelsmannAspen Re America InsuranceAsset ManagementAssociated PackingAT&TAthena DiagnosticsThe Sandra Atlas Bass & Edythe
and Sol Atlas FundLisa and Wayne AuerDorinda D. and Kurt L. BagwellCathy and Rick BaierBaker TillyDr. David and Dr. Leslie BakerThe Marvin L. Baker Family Foundation,
Inc.
Jay BalabanMr. and Mrs. Dan BaldwinMr. and Mrs. Bob BarnesBarona Band of Mission IndiansIrving BarrBarse Family FoundationThe Bank of KentuckyMr. and Mrs. Bruce BarshopSheri and Marc BassewitzRichard BassukAdriana Bauza and Gerry PowderlyBayer HealthCareBC International Group, Inc.BDBE+J Cattle Co.Jennifer and John BeardThe John and Frances Beck Family
FoundationBecker Family FoundationMr. and Mrs. Brett BeemanBelk, Inc.Robert and Kellie BelkBelle Foods (formerly Southern Family
Markets)Barbara and Terry BendrickMr. and Mrs. Freddy BenschBensonhurst Bayridge Kiwanis
Foundation, Inc.The Berge Auto GroupRichard and Barbara BergmanJames and Diane BerlinerRobert and June BerlinerToni and Steve BerlingerBernstein FamilyMr. and Mrs. Andy and
Cherrie BessetteCherry and Dave BetoSusan and Stan BeverCherona and Marty BicknellMr. and Mrs. Kevin BiddleEve and Richard BillerSondra and Gerald BillerBi-Lo CharitiesBJC HealthCareFlash BlackBonnie and Tom BlackmonBlackrock SolutionsMr. and Mrs. Wayne BlasingameBarbara and Roger BlauSandra and Michael BlockBlood SystemsBloombergBloomberg FinancialThe Bloomingdale’s Fund of
Macy’s Foundation
Bloomington Lions ClubBlue Cross Blue Shield of Alabama—
The Caring FoundationBlue Cross Blue Shield of ArizonaBlue Cross Blue Shield of
North CarolinaFrances BlumkinJohn BockThe Boeing CompanyAnn and Alan BogdanowBolling Charitable FoundationBon SecoursThe Bonanno Family and
Trattoria ReggianoBonanza BeverageBonner Family Private FoundationSheryl and John BooneBoston ScientificRosemary and Rebecca BradleyMr. and Mrs. William BradshawBrasfield & GorrieThe Bray FamilyBredemann Family of DealershipsLauren and Steve BrennerWarren BreslowJason Bridegum Trust Officer
Brady-Cashill FoundationBright House NetworksAmy and Tony BrineyMr. and Mrs. Chad BrinkleyBroadridge Financial SolutionsEstate of Seena Broodno Diane and Dorothy Brooks FoundationLynell and Brent BrooksBrothers Heating, Cooling
and PlumbingBrown & TarantinoCathy Springer Brown and Rick BrownMr. and Mrs. Craig BrownMr. and Mrs. Jeff BrownJessica and Colby BrownJill and Craig Brown Nancy and Thane BrownMr. and Mrs. Robert BrownBrubaker Family FoundationStewart and Mary Lou Bruce BuDu Racing, LLCCary and Kyle BurchElsa and Robert BurgLiz and Bob BurroughsRobert G. BurtonKathryn Brown Butler Family
FoundationKellie and Jesse ButlerLynn and Chad Buxton
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Byrne Family FoundationFlorence S. and Robert W.
Cabaniss FoundationCACTUS SoftwareGloria and Louis CairoMissy and Chris CalleroWendy and Brad CallowayJoAnn and Peter CalvanicoJennifer and Steven CampillayMr. and Mrs. John and Kelly CantillonLouis Yager Cantwell
Private FoundationThe Capital Group CompaniesMr. and Mrs. Victor and Laura
CaponeraCar PoolCarbo Ceramics, Inc.Laura and Francois CardinalMr. and Mrs. Chris CarlosMr. Mark and Dr. Pamela CarmainCarnrite GroupLisa and Rob CarpenterThe Carroll CompaniesThe John W. Carson FoundationMr. Tom CarusoAdam CasagrandeCash, Krugler and Fredericks, LLCMr. and Mrs. Jerry CashCasino ArizonaKarla and Scott CasselsCastle Montessori SchoolsCatholic Healthcare WestDr. and Mrs. Wright CaughmanCBRECBSCDM Resource ManagementEstate of Jack Turner CecilCentral BankCentral Pattern Co.Centric GroupCentro Inspection AgencyChadbourne & Parke, LLPCaroline and Stephen ChandlerNancy ChandlerChapman Family FoundationChicago Title Insurance CompanyChina Cables DirectChiquita Brands InternationalLaura and Bill ChisholmCHOMPChristensen Charitable Foundation, Inc.Dianne ChristensenCicchini EnterprisesCIGNACircle of Service FoundationCitiMortgage
City National BankClarion PartnersMs. Mary ClayClaycoCM Personnel Services, Inc.CognizantCognizant US CorpBetty Cohen and Darren LeedsNeil and Marcy CohenRhonda and Russell CohenSandra and Sheldon CohenMark and Breanne ColellaLisa and Gary ColemanCarol and Budge CollinsCommand Web OffsetCommonwealth BrandsCommonwealth of VirginiaCommunity Network, Inc.CompunetJohn and Marilyn ConnellyAlex Conti and Ellen DarlingChristopher and Linda CooleyChildrens Regional Hospital at Cooper Mark and Tracy CopelandCorday FoundationCore-Mark InternationalCorn Products InternationalArthur B. CornfeldDonald and Jennie CostnerCovanceCoventry Health CareMr. Courtney Holt Cowden Jr.Faye L. & William L. Cowden Charitable
FoundationThe Gerald and Daphna Cramer Family
Foundation, Inc.Laura and David CramerCarol and Denis CrawfordCredit Suisse Securities (USA), LLCCreditors Collection ServiceMr. and Mrs. Richard and Lynne CreedKaren and John CreelmanKitty and Tom CrishamBill and Pamela CrowderRichard and Alison CrowellDebbie and Guy CulpepperBradley Arant Boult CummingsCUNA Mutual Group FoundationJoanne and Fred CunhaLori and Sean CurranCurtiss Wright Flow ControlMr. and Mrs. Tom CusickMr. and Mrs. William CuttsCVS PharmacyPaul Czekanski and
Nancy Weber-Czekanski
D’Agostino SupermarketsKristin and Jeffrey DahlStacey and Don DaleGeorgia and John DallePezzeDr. William DanforthLaura Daniels and Jonathan LewisDariusData-Mail, Inc.Mr. and Mrs. Neil DaviesDavis Polk & Wardwell, LLPMark and Nancy DavisDavitaDebie and Dr. Bill DeatonCathy and Alex DebelakMrs. Anthony J. DeFinoMr. Dean Kamen/DEKA Research
& DevelopmentDana DelanyDellDelta Dental Plan of ColoradoDeltic Timber CorporationLiz and Frank DeniBecky and Michael DeNightMary Jane DenzerDrs. Cheryl and Michael DeVitoMr. and Mrs. Richard DeVosDexCom, Inc.Mr. and Mrs. Ramon Diez-BarrosoDignity HealthcareDIRECTVDr. and Mrs. Daniel DiverBarbara Donnell and Scott MarkusThe Doyle FamilySusan and William DoyleMegan and Stephen DragichMickey and Larry DrennanDrive Against DiabetesDrury Inns, Inc.The Duncan FamilyDebbie and Brian DunnDupont RefinishEstate of Gary DurbinEunice L. Dwan 1991 Irrevocable TrustMr. and Mrs. Christopher and
Bijen DyrekEagleBankMr. and Mrs. Jay Eastman Mr. and Mrs. John Eastman Pete and Martha EckerlineEdgepark Medical SuppliesRuedy and Allyson EdgingtonMark & Ann EdlenMr. and Mrs. Doug EdmanDebbie and Richard Egan/
Debbie’s DreamMr. and Mrs. John Eichhorn
14
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Jim Ellis and Maggie BradySusie and Peter EllisGina and Rex EllisonMargaret EllisonDennis and Bonnie EllmanEmdeonJohn and Kimberly EmersonEmpire BlueCross BlueShield EMWIGA FoundationEncore BeveragesRobert and Patricia Endries Family
Foundation, Ltd Energizer, Inc.DeeDe and Jerry EnnisEnquirer MediaMike and Sharon EnsignEpic Systems CorporationBobby EricksonEthiconDavid B. Ettinger M.D., DMD, and
Jacqueline EttingerExpeditorsExpress Employment ProfessionalsAl and Kathie FaccintoDr. and Mrs. John H. FainCindy and Robert FairchildFast Retailing USA, Inc. Ms. Susan Faulkner and
Mr. Donald SmithFederal Home Loan Bank of AtlantaFeld Family FoundationJudy and Richard FeldsteinMr. and Mrs. Carl Fellbaum Bruce and Lynn FeltMr. and Mrs. John FergusonJon and Jan FernandezFidelity Charitable Gift FundRuth and Lawrence FieldCasey and Aaron FielderFifty 50 Medical Devices, LLCFifty 50 PharmacyFilm FinanceTeam Brotherly Love/The Fine Family
and The Blick FamilyPhyllis and Henri FineFirst Independent BankFirstBankFirstBank Holding CompanyFirst Security BankFISMark and Lisa Fischer-ColbrieDr. Gerald and Marilyn Fishbone Team Fisher/Ashley and Michael FisherMegan and Larry Foley
Folsom ElementaryCynthia and Edsel B. Ford II/
Henry Ford II FundFreeman and Diana FordHarrison FordOrlene FossThe Foundation for Jewish
Philanthropies of San AntonioCathy and Kenton FourmanLarry FranklinThe Fraser Family FoundationFrechette Family FoundationSamuel Freeman Charitable TrustMr. and Mrs. Gregg FreishtatAmanda and Neil FriedmanLori and Robert FrielingLloyd A. Fry FoundationEstate of Frederick J. FurstEric GabrielsonTim and Jennifer GaleThe Gallagher Memorial FoundationTed GallowayJoan and Jim GardnerFrank and Amy GarrisonSteven J. GartnerGary Merlino Construction and
Stoneway ConcreteThe Gatherer Family FoundationKelly and Daniel GayGE EnergyThe David Geffen FoundationMr. Jay GeierGeneral MillsJames and Janice GeorgeToni and Harold GernsbacherDrs. Dave and Katie GesenswayGGP Limited PartnershipShahram and Neda GholamiWilliam and Shelli GialketsisJackie and Greg GiardielloGibson DunnGilbarco Veeder-RootAnna and Will GilfillanMartin and Susan GilmoreJoanne GimbelRobin and Dub GirandRosalind and Gene GlaserGlen Raven, Inc.Alvin Glick FoundationGlobal Bridge FoundationGohmann Asphalt & Construction Co. Janie and Brian GoldKay and Fred GoldenGoldman Sachs & Co.Rhonnie and Charles Goldstein
Golsen Family, LLCMr. and Mrs. Neil and Jane GolubGood Measures, LLCDiane and William J. GoodmanAndrew and Amy GordonDeborah and Stuart GordonMr. Keith GordonBarbara and Kenneth GoreBenjamin GoreGrafenauer FamilyMr. and Mrs. Steven GrahamThe Graves FoundationGreenberg TraurigKeith E. GreensponRoslyn GreensponNoel GreningJoyce Gresko and Sean RankinDebra and Bruce GrewcockDr. Donna Roy Grogan and
Mr. Paul GroganGroup HealthDr. Jaswinder and Monica GroverAndy and Julie GruberMr. and Mrs. Jerzy GruhnGuess? FoundationChristian and Cathy HaaseBarbara and Craig HakkioHallick HoldingsJames and Chulee HallickLynne and Harry HallowellRoger Hannay, Hannay Reels Patrick Hannon, Ed.D.Judy and Craig HansenLisa HansenHarbert Management CorporationSusie and Thornton HardieEric and Deidre HargerPete HarmonHarris, Crouch, Long, Scott & Miller, Inc. Chad HarrisMr. and Mrs. Warren HarrisAlice and Raymond HartkeMr. Ric Hartman and Ms. Kimberly
BrennemanNoel HarveyHatteras FinancialThe Helen G. Hauben FoundationJoy and Ralph HauserJudy and Walter Havenstein Sr. Hawn Foundation, Inc.Mr. Victor HaydelHayes & AssociatesMr. and Mrs. Holman HeadHealthways, Inc.Dan and Carolyn Heard
15
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Linda and Dick HeiderThe Heller Family FoundationJulie and Michael HellmersHenkelPatricia and Gary HennRichard HesterMary Heather and Mark HickmanMr. Peter J. and Mrs. Patricia M. HillMr. and Mrs. John HippHITT Contracting, Inc.James A. HixonCharley Hoffman Foundation
Las VegasMr. Thomas Hoffman Jr. and
Mrs. Erin HoffmanTim HoilesHoliday Health CareHolly Peterson FoundationHolman Automotive Mr. Frank HolmesLynne M. HolzhausenMr. and Mrs. Len HolzmanHome Box OfficeHarold HonickmanRay HopkinsRussell HoppensteinHorne Brothers ConstructionColin HorowitzBill and Jill HowardMs. Patricia Howard and
Dr. Donald LoganHowco Metals ManagementHSA Commercial Real EstateThe Harvey Hubbell FoundationGina and Clayton HughesJoe HugheyMarilyn HugheyHugo BossSam and Anne Hummel Roy A. Hunt FoundationNed HylandIBMIHS, Inc.IMA, Inc.IMGRosalind and David IngberInsperityInsulet CorporationIntelligent Medical Objects, Inc.International Society of SS Cosma
and DamianoInterpublic GroupIntuitIPA Foundation J & J Family Foundation
JabilJack in the BoxDr. Arlene Jacobs and
Mr. Allen FeltmanBeverly and Christian JacobsKerry and James JacobsonJaeb Center for Health Research, Inc.Laurie and Mike JaffeBrandon J. Janszen Family
Charitable FundSam and Leann JarczynskiAnita and James JenkinsGreg and Valerie JensenNan and Keith JensenJKS Family Foundation TrustJoanna’s Hope Fund Joey’s Pizza, Inc.John Moriarty & AssociatesThe Gary and Peggy Johns
Family FundJohnson & Johnson Allison and Gary JohnsonArdythe and Raymond JohnsonJim and Laura JohnsonLisa and Robert JohnsonEstate of Margaret and Dale JohnsonPitch and Cathie JohnsonJeff Jonas, M.D.Gene and Jerry Jones
Family FoundationHannah JonesLaura and Lowry Jones, M.D.Marvel and Ronald JonesCatherine and Thomas JoyceLundy and Steve Joyce, M.D.JP MorganSarah and Ron JuryJust AnswerKadima FoundationRobert J. Kahn FoundationKaiser PermanenteKevin Kaiserman, M.D.Eliot and Sandy KalterNancy and Mike KammererKansas City Marriott Downtown HotelCarol and Edward KaplanLeon and Mary Ellen KaplanEstate of Morton KarshJim and Sandy KatzmanJoan and Herb Kelleher
Charitable FoundationJohn KellenyiKelly Family FoundationKenan Advantage GroupKenandy
The Kibel FoundationCarla and Michael KilbaneEleanor M. Kilgour Living TrustElizabeth and Dr. Shane KimballAndrea KingClaudia KinneyJack and Lynne KirshnerKitsap BankBonnie and Lawrence KivelMr. and Mrs. Todd KlumokCary KochmanLynne KoenMr. and Mrs. Ed KohutekDarla and Jerry KollarMr. Edward R. Koller Jr.KOLO TV-8Kosair CharitiesKPMG, LLPRobert KraftKramer FoundationEstate of Catherine KraussSusan and Joel KreizmanCarolyn and Morris KremenDianne and Ure Kretowicz KrogerMr. and Mrs. David KruglerMr. and Mrs. Frank KudlaKurland Family FoundationAndy and Sarah KurtzigSandra KurtzigMr. Karl F. KurzBig Nick’s Team/Anne and
Nick KusmerWoo Fung KwongL&W SupplyLa Quinta Oscar LaskoLatham & Watkins, LLPMr. and Mrs. Mark LauriaMr. and Mrs. Jack and Mary LearyGreg and Dana LeeLee’s Discount LiquorLegault FoundationViolet and Matthew LehrerDr. and Mrs. Ron LeidenfrostMichele and Eric LeinerThe Annette M. and Theodore N.
Lerner Family FoundationPeter Levenson and Pamela SweeneyAnna Cheshire Levitan and
Richard LevitanLexus Pursuit of Potential Dealer
Matching FundsLibby’s/NTC Marketing, Inc.Mr. and Mrs. Frank Liberto
16
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Liberty Medical Supply, Inc.Elizabeth LiebmanLifeScan, Inc.LifeWise Health Plan of OregonMr. and Mrs. Julian LightLincoln Community FoundationLincoln Financial GroupLoren and Deidre LingenfelterDr. and Mrs. Dennis LiottaJoan and Bob LipsigDon Listwin and Hilary ValentineLocal EdgeLockton Companies, LLCDonald LocktonJacinta and Robert LoewenLonden CompaniesLormar FoundationLouisiana CNI, LLCLowenstein SandlerLowes FoodsMr. and Mrs. Steve LowitJacqueline and Richard LoyndLozier FoundationDon and Sarah LucasRichard and Lynne LucasLarry L. Luing Family FoundationLumina FoundationSusan and Daniel LundbergMarvin and Kristina LustigerKimberly Syman and Jonathan LyonKelley MacDougall and Mike PausicJane and Len MackesyTracy and Todd MackeyMackin’s Auto BodyMacy’s, Inc.Clark Madigan and Karen DavisFrances and Jerome MagnerMajor League BaseballMajor Leaque Lacrosse, LLCRobert E. MalloryCatherine and Peter MaloneGwen and Marc MaloneMr. and Mrs. John M. Maloney Jr.Abby Mandel Charitable FoundationSusan and Steve MandelMr. Andy and Joyce MandellEllen and Mark D. ManionPrem Manjooran and Susan BaikMelinda and Richard MannMarathon Oil CorporationArthur MarescaRobert Margolis FoundationMs. Jacqueline MaritzNoah’s Posse/Sherry and
Dave MarlettMr. Mel Marmer
Lisa and John MarquardtJane and Z. Marshall Randy MartellMartin, Harding & Mazzotti Kara and John MartinMasimoMassapequa Youth Lacrosse ClubLisa and Luke MassarMatt Smith Physical TherapySheila and Bill MatthewsBarbara and Hank MawickeLouis and Manette MaybergMazdaSarah and Bryan MazlishMcCownGordon Construction, LLCMcDonald’s CorporationRenee and Ed McDonoughGraham’s Group/Melissa and
Matthew McGinnesVirginia McGuire FoundationNatalie Reitzel McMahonCarole and Mark McNameeLaura Mecory and Cary WalkerThe Medical Center of PlanoMedicAlertGreg and Kari MeehanDavid MeierAlan and Amy MeltzerMenasha Corporation FoundationMercy Medical CenterMerrill Companies, LLCMerrill Lynch/Bank of AmericaMeru NetworksMesirow Financial Methodist Medical Center of IllinoisThe Meyer Charitable FoundationMGM Resorts FoundationMichigan GWRRA Chapter GMicrometl CorporationMid Atlantic Resource Group
FoundationMilestone Venture GroupMillennium Management FoundationAndy and Susie MillerCindy and Rich MillerJanet MillerEstates of Edith and Irving MillmanMr. and Mrs. Jerry Mirochnik MMK FoundationMobilMobile MDHoward and Judy MockMoen IncorporatedB.J. and John MoffittMr. and Mrs. Andy MoninValerie and Frank Montecalvo
Monument RealtyJohn and Karen MooreMorgan Family FoundationMorgan StanleyMr. and Mrs. Kevin and Rebecca MorrisMr. and Mrs. Alan MosesEstate of William D. MosherJ.M. Mossman Charitable TrustMostyn Foundation, Inc.Susan and Paul MoweryMSC Industrial Supply, IncMulti-ChemMulti Pack SolutionsLes and Pam MumaJim and Claudia MunakMunck Wilson Mandala, LLPRonald and Janeane Munman Family
TrustMurdoch’sMr. and Mrs. Anthony MurphyMara and Keith MurrayPayson and Grant Murray Payson Robbins Murray via the
James O. Robbins Family Charitable Lead Annuity Trust
Pam and Jim MuzzyNathaniel’s Rainbow RidersNational Aviation AcademyNational Basketball AssociationNational Postal Mailhandlers UnionMarlene and George NaumanNBC UniversalNCAADenise Neary and Christopher KellyNeBAAEric NeedlemanJoe and Karen NeihausJim and Susan NelsonEstate of Lucille NelsonMr. and Mrs. Randy NelsonNestle Waters North America, Inc.David NestvoldNew Breed Logistics New Hanover Regional Medical CenterNew York Media, LLCThe New York Mets Foundation, Inc.The New York Times CompanyNewbury ComicsDr. and Mrs. Stephen NewmanAmy and Thomas NiceJohn and Lori NiehoffPeter J. NolanCathy NordlingJulie and Gary NordlundPhyllis NordlundJohn and Jennifer Nordstrom
17
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Janice and Daniel NormanThe Norris FoundationNorwood FoundationDebbi and Paul NottinghamNovant/Forsyth Medical CenterNovartis Pharmaceuticals Michael and Beth NowakCarrie and Jed NussbaumNuStarOakland A’s Community FundOC Auto TeamOceanic Heritage Foundation Mr. and Mrs. John O’ConnellSylvan and Ann Oestreicher
FoundationKim Ogden and Frank HuntowskiEugene and Catherine OhrKim and Peter OldhamOliver WymanTravis and Laura OliverO’Neal SteelOracleOSI Restaurant Partners, LLCThe Oswald GroupBill and Norma OvertonPaccar, Inc.Pace CommunicationsDonna Pacicca, M.D., and
Dominic DeCiccoCatherine and Michael PaessunDr. Graydon T. and Shelley J. PageCindy and Bob PailetSteve and Tamara PannAngela and Trey ParkerMr. and Mrs. Howard ParkerNorma ParkerParker’s PackVarsha and Vikas PatelLoretta and Douglas PattersonMike PausicDr. and Mrs. Net PayneMichael PeacockPearsonLiz and Ralph PeerpeermusicPenguin Group U.S.A.Bob and Leslie PenkhusAnne PennDr. and Dr. William and
Jennifer PennoyerPerfection Hy-TestElise and Carl PerkinsPermaterMarilyn and Phil PerriconePerrigoMarsha and Jack Petcove
Dr. Caroline Peterson and Ms. Cindy Shafer
Karen and Paul PetersonMarty and John PetersonNancy Petry and William WhitePGA Tour, Inc.Cathal PhelanPierce Family FoundationVicki and Robert PierceAnn and Bob PillionNancy and Bret PilneyJanet and Kevin PistilliPlainsCapital BankBleakley PlattJon and Angie PlattPNC Wealth ManagementPatrick and Laura PohlenThe Pointer FoundationRoy PolatchekJudith and Matthew PollackSusan and Bruce PollackJason PollardPortland Metro Auto DealersCarolyn Powell and Marshall LaitschJohn PowellPPDPratt & WhitneyPresbyterian HealthcareLinda and Richard PricePrime International Trading, Ltd.Estate of Lucille PrincePrinova US, LLCProfil Institute for Clinical ResearchMr. and Mrs. Chris ProlerMr. and Mrs. John PruittThe Puntel Family TeamPWCQdobaR & R PartnersRackspace Managed HostingStephen and Anne RaderRadiology Associates, P.A.Susan and Paul RankinMr. and Mrs. Derek RappRascal FlattsCindy and Steve RasmussenMr. and Mrs. Dan RatherKathi RawnsleyRaynbow FoundationMorgan and Carolyn RectorRed Ball OxygenErin and James RedfearnReedy Industries, Inc.Mr. and Mrs. Trevor Rees-JonesBobbi and Robert ReitzesRevital and Ben Reitzes
Kerrie and Jerry RellihanReno PropertiesMr. and Mrs. Daniel ReversReynolds American, Inc.Reznick GroupGinny and Chris RichMr. and Mrs. Michael RichCamilla and Scott RichardsonMr. Mark RichardsonSeymour and Sandy RifeMr. and Mrs. Michael RiordanJames O. Robbins Family Trust Natalie RobergeGrace Roberti FoundationThe Roberti-Legault FoundationRoberts Law FirmDeborah and Mike RobertsKathryn RobertsJohn Alex RockefellerDr. Lynn Rogers and Dr. Stuart
DonovanIngrid and Scott RollesMrs. Jean E. RollesMs. Nancy RollinsRopes & Gray, LLPCarol and Walt RosebroughSteve RosemanDonna and Richard RosenbergEugene and Maxine RosenfeldThe Rosskamm FamilyKathy and Louis Rotella Jr. Mr. and Mrs. Arthur J. and Nancy RothRowling FoundationLauren and Cayce RoyRoyal Bank of CanadaMay Mitchell Royal FoundationCelia RumseyBrooks RunningClaudia and Steven RussellMr. and Mrs. Frederick Russell Jr.Kerry and Tim RuthLidia and Pat Ryan, Ryan
Enterprises GroupPatrick G. and Shirley W. Ryan
FoundationTim Ryan and Michelle MundtS&D CoffeeColleen and Michael SacaMs. Dorothy SadlerSafeco InsuranceSaint Francis Hospital and
Medical CenterMr. and Mrs. Allen SalikofSalt River Project Terry SaltzbergSamson
18
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Samson Capital AdvisorsSamuels & AssociatesMr. and Mrs. Robert and
Renee SamuelsT. Denny SanfordSangamo Biosciences, Inc.Joseph and Joan SangiminoMichael and Diane SapirSara Lee CorporationSara Smith Self FoundationSaratoga Casino and RacewayHeather and John SargentSusie and Rob SavageSavitsky, Satin & Baconsbe EntertainmentScafcoPaul Scammell FoundationScaramucci FoundationMr. and Mrs. Joel and Debbie SchallerLisa and Lee SchalopBonnie and William SchriatoDiana and Steve SchiroHeidi SchmeddingMichele and Kurt SchmitkeEstate of Rose SchneerErich SchoenkopfShawna and Eric SchoonveldSara and Steven SchrammChris SchultzCharles and Helen SchwabKathleen and Peter SchwaljeBob and Mimi SchwartzAngela and Andrew SchweigerSeagull Golf Classic honoring Kaitlyn
Santala and Amber McCallKristi SelfSellers, Richardson, Holman &
West, LLPMarsha and Jerry SesloweSg2Molly Shaffer and Paul MinoriniShakopee Mdewakanton
Sioux CommunityPaul and Janice ShapiroValerie and Lee ShapiroAnn and Stephen ShermanJohn and Marny ShermanThe Sherwin-Williams CompanyHugh ScheurerJaleen and Michael SiekmanSigma-Aldrich CorporationNaomi SilkSilver Legacy ResortMr. and Mrs. David SilversteinSilvestri WineriesSimon & Schuster
The Sidney, Milton and Leoma Simon Foundation
Stacy and Bruce SimonSimonizJim and Mary Claire SimpsonWebb and Dowd SimpsonSingh Charitable FoundationBarb and Steve Slaggie/Slaggie Family
FoundationSara and Greg Poulos c/o Slaggie
Family FoundationSloan ValveSmart Pill, Inc.Smith/Roach Memorial
Golf TournamentIsabelle Morrison-Smith and
Leonard SmithJeanne and Richard SmithPatty and Greg SmithSusan and Robert SmithDeeDee and Don SodaroMarc and Audrey SolomonSonora Quest Laboratories of TucsonMr. and Mrs. Michael SoperLauren and Larry SorrelJeffery and Mindy SoslandSpark DesignSpark EnergySean and Jennifer SpectorJulie and Stephen SpencerThe Spiritus Gladius FoundationEmily SpitzerSpring Gathering Charity Horse ShowEssie and Steve SpringerSprintVirginia and Richard SrednickiSusan and Kenneth StackMr. and Mrs. Russ StaltersDarren Star FoundationStarbucksJim and Amy SteeleSteelFabMr. and Mrs. Larry SteinSTERIS CorporationBruce and Judi SternThomas D. and Denise R. Stern
Family FoundationSteve and Betty SterrettMark StevensMr. and Mrs. Mark StevensKaren and Terry StewartTeresa and Glen StewartLorraine and Chris StiehlOmer and Karen StockerMr. Sam Stolbun and Dr. Alana SpiwakJennifer and George Stone
Stradling Yocca Carlson & RauthKaren and Mark StrauchMeryl Streep—Silver Mountain
Foundation for the ArtsElizabeth P. Streicher and
Lionel C. EpsteinJohn StropkiTom and Peggy StyerSuffolk Construction CompanySullivan & Cromwell, LLPSolon E. Summerfield Foundation, Inc.Sun Capital Partners FoundationSuntrup Automotive FamilyMr. Thomas SuntrupSwat FameSwearingen FoundationMadalene and Wayne SwetnamSXC Health Solutions, Inc.Sycuan Band of the Kumeyaay NationSymphony TechnologiesSynacorSysco Corporation Maureen and Andrew SzafranT&S Brass The Taddeo FamilyTalent Plus, Inc.Tanamera ConstructionP. David Tarter and Karen E. SchoolsThe Taubman Company, LLCBryan and Courtney TawTaylor Farms California, Inc.Taylor International CorporationRick and Lisa TaylorTD AmeritradeTD Bank TeamPraxis, LLCTech Group North America, Inc.Franklin TempletonJennifer and Michael ThoeleJoanne Thompson and
Thomas RooseNancy and Bill ThompsonThomson MacConnell CadillacSusan and Richard ThomsonTeam Kayla TibbitsThe Tiberti CompanyTickets for Charity, LLCCarmen TiritilliTishman SpeyerRobert P. and Linda L. Tjossem,
Julianne TjossemJoanne and Alfred TobinMark TomlinCynthia B. Tomlinson FoundationTorque FoundationToyota Motor Sales
19
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Traylor Bros., Inc.John Trexler TriMark SS KempTrinet/All Systems BroadbandTrokhan Family FoundationBarbara TrottaCindy and Bob TucciTucson Medical CenterMr. and Mrs. Peter TumminelloCassidy TurleyTurner Mid-AtlanticMyron and Ruth TurnerTracy and Chris TurnerThe Tutera GroupUBSUC HealthJodi and Thomas UllrichUNC/Rex HospitalsUnion BankUnit CorporationUnity Health InsuranceUniversal Scrap Metal, Inc.University HospitalsU.S. Trust, Bank of America Private
Wealth ManagementUSI Insurance ServicesUSS-Posco IndustriesUW HealthScott and Antonella VaccaroPaul and Lisa ValentineJack Van ValkenburghMr. and Mrs. Paul VanceVandco EquipmentThomas VanderMolenMr. and Mrs. Thomas VanderMolenVanderWeide Family FoundationVantivRosemary Haggar Vaughan Family
FoundationVCU Health ServicesMegan VeldeeLamar Bruni Vergara TrustSarah and Porter VergonVF CorporationGail VictorMr. and Mrs. James VilleneuveVML FoundationMr. Chris and Hollis VolkVornado/Charles E. SmithThe J.E. and Mildred Waggoner Family
FoundationBruce and Beverly WagnerPatricia and Daniel WagnerRichard and Edith WaldMilton and Miriam Waldbaum Family
Foundation
Cary Walker and Laura MecoyEstate of Lillian K. WalkerJoan and Milton Wallack Derrick Wallery/Marque MedicosWal-MartJ. and J. Walsh Family Charitable FundPJ Walsh Family FundThe Warburg Pincus FoundationJohn H. Ware IVWarner Bros EntertainmentThe Warranty GroupPaul and Sally Wasikowski
Charitable FundMr. and Mrs. Robert WattsThe Weatherspoon Charitable
FoundationLindsay “Butch” WeaverJulie Kate WebsterMargaret and Thomas WeekleyLeslie and Michael WeintraubJayne WeissWanda and Delmer WeiszJulie and Dennis WellnerKami and Paul WeningerWest CorporationRenée WestMr. and Mrs. Jim and Pam WhalenWhispering Vine Wine CompanyWhite River Coal SalesMr. and Mrs. Colt WhittallMelissa and Steve WigginsWILD FlavorsKatie and Company/The Wiley FamilyWilliams Trading, LLCDr. and Mrs. Byron WilliamsSarah and Daniel WilliamsWillis North America, Inc.Willis of ArizonaWillow House, Inc.Shea Wills and Marcus WescheThe Windward FundPatricia and Steven WinegarWinston & Strawn, LLPAnn and Marc WinthropWipro, Inc.Bruce and Marci WisemanMike WisnieskiKatie and Jason WittmerMr. and Mrs. Barry WolfJane and Richard WolfMr. and Mrs. Lawrence A. WolfLinda and Jeffrey WolfsonWomble Carlyle Sandridge & RiceWood-Claeyssens FoundationStaci Wood and Steve GrapenthienThe Woodmere Club
Ellen and Stavely WrightTerry and Dana WrightBeverly and Bruce YoungYoung’s Jersey DairyAndrea and Frank ZieglerJodi and Mitchell ZietsFaye and Frank ZimmermanChristina Zuckerberg
20
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FISCAL YEAR 2012
BETA Society Members
The BETA Society recognizes people who have included JDRF as a beneficiary in their estate plans.
The list below honors BETA Society members who made new planned-giving commitments to
JDRF in fiscal year 2012.
Anonymous (33)Bonnie and Anthony AndriseCatherine Marie ApostleWilliam ArzbaecherAdam BarCarole BeamerNatalie BelliniAngela Beltran and Jean-Paul LausellBarbara and Terry BendrickJennifer Bennett and Douglas MaysHoward BernickGinger and Thomas Blackmon Jr.Deborah and Jeffrey BrewerTimothy BuckinghamRobert and Elizabeth BurroughsJo Ann and Peter CalvanicoCathy ChisholmLinda Christopherson and
Charles Ray TylerCathy and Tommy ChristyTerry and Peter ConnRebecca DaviesDebra Davis FamilyKay DavisEuline D. DavissonMaarten B.T. de GrootDiane and Joseph DeMarcoCherie EllifritsRoslyn FeuerDebbie and Timothy FogartyDr. and Mrs. Harold E. FoxBarbara de FranceauxLeigh Ann and Michael GallucciReed GarrettAnita Geach and Tony FerlautoCarine and Jeff GirardinTimothy Gognat
Elisa and Gregory GraceffoNancy and Don GrayKeith GreensponNoel GreningVirginia HartleyFrank Ingrassia and Elizabeth McCaulNicole JohnsonMark KacherFrederick KaubWill KoepselSuzanne Kotz and Stephen TarnoffCindy and Steven KramerSarah LaneLarry and Donna LeshJudith and Rabbi Richard LevineTammy and Todd LoomisThe Lucas FamilyLaura and Clark MaciagJill and Steve MaddyHollie and Michael MangieriGeorgina and Wayne MarionFlora and Stuart MasonForrest Edward MattixAlvina McHaleRose and Adam McLaughlinMary Ann and Wayne MooreFrances MortonSylvia MoskovitzMary North MulierKelli and Burke NevilleMelissa and Kevin NewmanJulie and Gary NordlundKim and Peter OldhamCarol OpsalBonnie and Charles OrvikCindy and Robert PailetBarbara and Ronald Pearce
Regina PearlmutterSumner and Scott PrakkenAbigail and William PropstCarol PyleEmily and Derek RappDiane and Gene ReinessDaniel RosenblattDonna and Paul RosenzweigRebecca and Steven SantoliLois SatalofSandra and Carl SchusterJodi and Alan ScottNancy and Louis ShepardLinda and Darin ShortJill and Michael SlapnikDaron SmithPatricia S. and Robert D. SmithKat and Michael TeenAmy and Jason ThompsonDrs. Deb and Charles TomekNancy and Alden TuellerMarilyn ViauIn memory of Susan Davis WallSylvie WeikertBarbara and Marshall WeingardenWanda and Del WeiszMildred and Alton WendzelGloria and Bob WerthElizabeth and Bruce WillsonMaria and Mark WilsonKenneth WinnMark S. Yanochko in memory
of Debbie GarretAlison and Thomas Youkilis
21
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FISCAL YEAR 2012
Stem Cell Research Fund
JDRF expresses our deepest gratitude to the following supporters for their generous donations of $10,000
or more to the JDRF Stem Cell Research Fund. These donors, and many others, have given more than $19
million since the fund’s inception in fiscal year 2002. Their vision ensures that JDRF can continue to pursue
stem cell research, which holds such promise for a cure for T1D and its complications.
Anonymous (2) The Judith and Jean Pape Adams
Charitable Foundation Alagem Capital GroupSusan Alberti, AM*Mrs. Kathleen Albrecht and
Mr. Pete McCormick Andrew Family Charitable Foundation Helene and Allen Apter Ares Management LLP Veronica Atkins Karen Barfoot* Bonnie and Tom Blackmon The Bloom and Mittel Founding
Families of the Greater Bay Area Chapter
Quent and Inez Boyken William K. and Delores Brehm Broidy Capital Capital Guardian Trust Richard and Elizabeth Carrell Chartwell Charitable Foundation Dean and Shirley Chenoweth Clarity Partners Irene and Seymour Cohen Comerica Bank Ken and Sherry Corday Thomas and Wendy Cramer Creative Arts Agency Alison and Richard Crowell Jaime Davila Lawrence J. and Florence A.
DeGeorge Charitable Trust Danny DeVito and Rhea Perlman Eunice L. Dwan 1991 Irrevocable Trust EMWIGA Foundation Entertainment Industry Foundation
Joel and Marcia Faber Allen Feltman and Arlene Jacobs, M.D. Mr. and Mrs. Simon C. Fireman First Republic Bank Marilyn and Dr. Gerald Fishbone Greg Fisher and Family The Ella Fitzgerald Charitable
Foundation Jeanine Forman-Ham The Lauren Gatlin Stem Cell and Beta
Cell Research Initiatives Fund Geffen Foundation James Gorton Greenberg, Glusker, Fields, Claman
and Machtinger Clay Hammerstein and Family Michael Heine* Michael and Loretta Helfant Stephen and Roey Higgs* Hille Foundation Irell and Manella, LLP Frank and Sophia Jackson* Robert Wood Johnson IV Julie and John Johnston Damien and Yvonne Jordan Marjorie and Maxwell Jospey, in
memory of their daughter, Jane Jospey Cobb
Marjorie & Maxwell Jospey Foundation WM Keck Foundation The Kennedy/Marshall Company Brent Kessel and Britta Bushnell Taras and Kristen Kihiczak Laurie and Alec Kouyoumdjian Gilda and Murray Lappe Latham and Watkins LLP Eason and Ellen Leak
The Lee Family Fund Lewis-Sebring Family Foundation Richard and Jacqueline Loynd The Joseph D. Maio Scholarship Fund Sharon and Tom Malloy Alfred Mann Fred and Susan Mardell Andy and Terry Marx Foundation Douglas Matheson—Illinois Tool Works Helen and William Mazer Foundation Brian McCarthy Michael and Kimberly McClain Charles and Aniela McCool McDonough Family Foundation In honor of Allison McDonough The Giles W. and Elise G. Mead
Foundation Marianne and G. Allen Mebane Matthew Meister Steven G. Mihaylo Mr. and Mrs. Gary Millican, in honor of
Alexander Millican and in memory of Roy E. Millican Jr.
Mary Tyler Moore and S. Robert Levine, M.D.
Jim and Susan Nelson Nicholl Family Foundation, Inc. O’Melveny and Meyers Bert C. O’Neal, in honor of Lisa and
Jack Reed and Elizabeth Shannon In honor of Kathy and Mark
Papermaster, Kathy and Steve Papermaster, and Gail Papermaster and Dave Mattson
Paramount Pictures Lorna and Gary Pederson Lea and Barry Porter
22
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PR 21 Kay and Jay Proops Mitchell and Nina Quaranta Steve and Anne Rader Mr. and Mrs. Jack Reed Jr. Remy Investors Jamie and Anthony Ressler In honor of Mr. and Mrs. David I. Roos
Jr. and family, in memory of Debbie Roos Hoppenfeld
Jan M. Roswig Sheila Royles* Renee and Robert T. Samuels Scudder Investments and Deutsche
Asset Management Elizabeth O’Neal Shannon and Jack
Herbert Shannon In honor of Elizabeth O’Neal Shannon Mrs. JoAnn Shull In honor of Mrs. JoAnn Shull and in
memory of her daughter, Candy Mr. James M. Shure and Family Kelly and David Siegel Reagan Silber—Edge TV Sandra and Alan Silvestri Victoria Mann Simms Skadden Arps Marianne and Roy C. Smith Sony Pictures Entertainment Brenda and James Souers In honor of Barry and Mimi Sternlicht Jim and Susan Stuart Jr. Tiscornia Foundation TransAmerica Trench Shoring Co. Jami and Nicolaus Von Heidegger Warner Brothers Pictures Casey Wasserman Charles and Mary Jane Wick Cynthia Wick and Channing Gibson Doug Wick and Lucy Fisher David and Terry Wohlberg Mr. and Mrs. William T. Young Jr. Anne and Allen ZaringJulianne and Todd Zeile Robert Zemeckis—Image Movers
Names in boldface indicate donors to the Nucleus Fund*Australia
23
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Message from the Chief Financial Officer
In the link below, we present the detailed financial statements of JDRF as of June 30, 2012 and 2011. The charts above
illustrate a breakdown of expenditures in both real dollars and percentage of total income. The second chart illustrates the
outstanding operating efficiency of JDRF, with 81.7 cents of every dollar going to program services.
Although growth fell short of projected goals in 2012, JDRF raised more than $175 million in public funds in the United
States. Another $20.9 million was contributed by our international affiliates. From these funds, we have been able to put
more than $110 million to T1D research efforts.
In 2012, JDRF made necessary strategic investments in organizational systems and infrastructure that we are confident will
yield positive return in the long term but occurred too early to impact 2012. Our goals for a significant revenue increase in
2013 are ambitious, and we are aggressively seeking funding to meet these goals.
Thank you to those who have guided and supported JDRF through a challenging economic climate and a period of
significant internal change. We have emerged better positioned to continue to lead the global research community in the
fight against T1D. Together, we will create a world without T1D.
Edward Sebald
Chief Financial Officer
To view the full Audited Financial Statement, please visit jdrf.org/2012financials.
PUBLIC SUPPORT AND REVENUE $193.0Mfor the year 2012
n Contributions: $51.4M
n Special Events, Including Walk: $123.7M
n International Affiliates: $20.9M
n Investment Return & Other: $(2.9)M
FUNCTIONAL EXPENSES $204.7Mfor the year 2012
Research & Education Programs: $167.2M
n Research: $123.9M
n Public Education: $43.3M
n Management & General: $14.7M
n Fundraising: $22.8M
81.7%
60.6%
7.2%
21.1%
11.1%
-30
0
30
60
90
120
150
In Millions
$123.7M
$51.4M
$20.9M
$(2.9)M
Please visit jdrf.org/2012annualreport
to view the entire Annual Report online.
24
25
FISCAL YEAR 2012
Board of Directors
Diane Adams
Fernando Aguirre
Dick Allen
Shannon Allen
Richard K. Bonness
Mary Elizabeth Bunzel
Mitchell H. Caplan
Karen Case
Tom Chapman
Matthew Cohn
Rebecca Davies
Maarten de Groot
Cynthia Ford
Chip Halverson
Michael L. Hendren
Steve Hitchins
Francis J. Ingrassia, Chairman
Richard Kirkland
Ellen Leake
Douglas Lowenstein
Red Maxwell
James F. McDonald
Patrick McFeeley
David W. Nelms
Carol Oxenreiter
Gail Pressberg
Derek K. Rapp
David K. Rehr, Ph.D.
Lorne Shiff
Lorraine Stiehl
Glen E. Tullman
Please visit jdrf.org/2012annualreport
to view the entire Annual Report online.
26
FISCAL YEAR 2012
Board of Chancellors
Dr. Susan Alberti, AO, HonLLD
Don Aron
Robert Auerbach
Aubrey W. Baillie
Gordon D. Barker, R.Ph.
Maureen Barunas
Joan Beaubaire
Crandall Bowles
Erskine Bowles
John Brady
Jeffrey Brewer
Max C. Chapman Jr.
Sanford Cloud Jr.
Judi Cochran
Dayton Coles
Ross A. Cooley
Don A. Corrao
Lee Ducat
Samuel D. Ewing Jr.
Gerald Fishbone, M.D.
Joseph Gardner, Ph.D.
Eileen Gelick
Robert D. German, Esq.
David Glusman
Krayna Golfman
Marilyn Gomm
William Graves
Roslyn Greenspon
Eric Harkna
Margaret Conn Himelfarb, MPH
Michael J. Hopkins, Esq.
Judy Hunt
Terry A. Jackson
Fran Jacoby
Ardy Johnson
Dave Johnson
Larry King
Robert N. Klein II
Anne Lacey
Joann Leatherby, Esq.
Jan Leeper
Stephen Leeper, DDS
S. Robert Levine, M.D.
Richard Levy
Carol Lurie
James M. Lurie, Esq.
John J. McDonough
Steven M. Merdinger
Mollie Miller
Penny Moseley
Leah Mullin
Leo F. Mullin
J. Richard Munro
George R. Nethercutt Jr.
Katharine S. Overlock
Mike Overlock
Nettleton S. Payne II, M.D.
Penn Payne, Esq.
Margery D. Perry
Gail Pressberg, Chair
Sandra Puczynski, Ph.D.
Charles J. Queenan III
Kenneth M. Rich
Mark Rubenstein
Steven T. Ruby, M.D.
Lewis R. Runnion
Pam Sagan
Robert Samuels
Alyce Satsky
Helaine Shiff
Sandra D. Silvestri
Adam Singer
Harold Smethills
Roy C. Smith
Emily Spitzer
James Stuart Jr.
Michael White
Peter A. Wilson
William T. Young Jr.
Anne Zaring
Please visit jdrf.org/2012annualreport
to view the entire Annual Report online.
27
FISCAL YEAR 2012
Senior Staff
Jeffrey Brewer President & Chief Executive Officer
Richard A. Insel, M.D. Chief Scientific Officer
Edward Sebald Chief Financial Officer & Assistant Treasurer
Gerri Feemster Bostick, SPHR Senior Vice President, Chief Human Resources Officer & Assistant Secretary
James Szmak Chief Operating Officer
Scott McCormick Senior Vice President & Chief Marketing Officer
Cynthia Rice Vice President, Government Relations
Diana Gray, M.A. Vice President, West Division
Patrick McKenna, Esq., FACHE Vice President, East Division
Linda C. Saulnier Vice President, Central Division
John Vranas Vice President, Fundraising Programs
John McGuire, CFRE Vice President, Development Strategy and Planning
Margo Lucero Vice President, Strategic Corporate Alliances
Gil King Vice President, Internal Audit
Peter Cleary Vice President, Communications
Julia L. Greenstein, Ph.D. Vice President, Cure Therapies
Aaron J. Kowalski, Ph.D. Vice President, Treat Therapies
Robert Swanson Assistant Vice President, IT Operations
Sridhar Thodupunoori Assistant Vice President, New Technology Programs
Please visit jdrf.org/2012annualreport
to view the entire Annual Report online.
1
JDRF Research Top 10 Advances of FY2012
JDRF Cure Research Halting the autoimmune process and restoring normal insulin production.
Targeted Immune Rebalancing Therapy Starts Clinical Study A JDRF-supported study launched at the University of California at San Francisco is enrolling patients with recent onset T1D to test a therapy for rebalancing their immune system. A patient’s “T-regs” (cells that regulate the immune system) will be grown in the lab then re-infused to the patient. The hope is that these added T-regs will halt the destructive “killer” T-effector cells that attack beta cells. This milestone represents the first human test of such a T1D therapy. (Learn more at clinicaltrials.gov)
An Explosion of Newly Discovered Beta Cell Regeneration Pathways Four JDRF-supported researchers (from Pittsburgh, Stanford, Zurich and Jerusalem) have identified unique and new pathways that control beta cell proliferation and might be activated with novel drug therapies. Some have even been turned on with prototype drugs in animal studies; others are at an earlier research stage. The concept of drugs to stimulate beta cell proliferation is becoming a reality. Drugs exist to promote cell proliferation in other diseases; hopefully one of these newly discovered pathways will yield a T1D drug for beta cell proliferation in the future. (Learn more at jdrf.org/betacell/regeneration)
Invention of Novel Oxygen-Producing Biomaterial for Beta Cell Encapsulation Implanting encapsulated beta cells in a person with T1D could make them independent of external insulin use, but several hurdles exist. The key challenges are keeping the cells alive with oxygen and nutrients and protecting them from further immune attack. JDRF-supported researchers at the University of Miami invented a new type of biomaterial that produces oxygen to sustain beta cells immediately after implantation. This novel biomaterial should accelerate beta cell encapsulation progress by overcoming a key technical hurdle. (Learn more at jdrf.org/betacell/replacement)
Blood Test for Beta Cell Death Discovered Current tests to detect and measure T1D are crude and cannot directly measure beta cell death. JDRF-supported researchers at Yale University discovered a new blood test that measures the release of beta cell DNA after they die. In mice, it could distinguish between mice with and without T1D. Better tests will allow earlier T1D detection and treatment by signaling the first signs of the disease process at the beta cell level. Such tests could also speed clinical studies of promising new therapies by allowing more rapid assessments of the effect of a new therapy on beta cell survival. (Learn more at jdrf.org/cureTID)
JDRF Treat Research Developing new devices and therapies that optimize blood sugar control and treat or prevent T1D complications.
FDA Issues Draft AP System Guidance as a Result of JDRF-Led Effort JDRF-led grassroots advocacy including support from professional clinical associations helped drive FDA to produce draft guidance for development of artificial pancreas systems. While JDRF provided FDA suggestions to improve the draft guidance, the expectations for clinical studies and approval of such systems are reasonable. JDRF is working closely with the FDA as the draft guidance is finalized. This guidance will speed JDRF’s APP clinical studies, especially outpatient studies, by informing researchers and companies of FDA’s recommendations. (Learn more at jdrf.org/app/plan)
2
JDRF APP Consortium Conducts the First Real World Test of an Artificial Pancreas System Previously, all APP human testing had been done in a controlled hospital setting to be certain there were no significant safety concerns and because of the lack of regulatory guidance for such systems. The JDRF-supported study of a handheld device for controlling insulin delivery performed well in controlling non-mealtime insulin requirements. JDRF-supported real world testing in the US has recently begun, coordinated by the University of Virginia. Real world testing of AP systems moves them a big step closer to delivering them to patients. (Learn more at jdrf.org/app/plan)
JDRF Challenged the World to Invent Glucose Responsive Insulin Products for T1D A glucose responsive insulin (GRI) would release insulin in the body only when needed and might be taken only once daily or once weekly. JDRF issued a $100,000 Challenge Prize to anyone who could develop a novel way to achieve a GRI product. JDRF will announce the Challenge Prize winners in summer 2012. JDRF is seeking creative solutions for novel T1D products from anywhere around the world; expanding the pool of talent focused on discovering and developing new T1D products. While still at an early stage, such a GRI product could transform T1D management. (Learn more at jdrf.org/gct)
Novel Markers of Kidney Disease Risk in T1D Discovered Kidney disease is a serious complication of T1D and is very difficult to predict in people with T1D, since not everyone with T1D develops it. JDRF-supported researchers at the Joslin Diabetes Center in Boston have discovered proteins in the blood that are strongly associated with kidney disease risk in people with T1D. This finding could form the basis of a simple blood test for kidney disease risk in people with T1D. The earlier identification of someone with T1D at risk for kidney disease will allow earlier treatment and better management of this serious T1D complication. (Learn more at jdrf.org/complications/prevention)
JDRF Prevent Research Preventing the autoimmune process from starting or stopping it before the onset of insulin dependence.
Focused a Novel Vaccine Technology on T1D Prevention Targeted T1D vaccines are ones focused on the specific beta cell components to which the immune system mistakenly reacts. A vaccine focused on these beta cell components could stop the autoimmune process before a person becomes insulin dependent. JDRF is supporting this unique nanoparticle-based vaccine technology by partnering with Selecta (a Massachusetts based company) to ensure they focus their efforts on T1D, something not previously a priority for them. Vaccine research is one of the most promising approaches to prevent or halt the beta cell-specific autoimmunity in T1D. (Learn more at jdrf.org/prevention/strategy)
Strengthened the Link between Enteroviruses and T1D Enteroviruses are small viruses often found in a person’s gut. Previous studies have linked them to T1D but the connection was not clear. This new JDRF-supported research in Finland has now shown that enteroviruses can become a persistent infection in the gut lining of people with T1D and showed they can cause related inflammation, potentially a trigger for the T1D autoimmune response. Development of a vaccine or anti-viral agents that target these enteroviruses may be a possible T1D prevention strategy. (Learn more at jdrf.org/prevention/strategy)
- Your Generous Support of JDRF Made These Important Advances Possible - Thank You!
June 2012