Integration architecture
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Integration architecture • Queryable sources that generate XML • Distributed queries over sources • Query Manager to manage queries • Saved queries as sources that can also be queried • Leads to potential for query networks
description
Integration architecture. Queryable sources that generate XML Distributed queries over sources Query Manager to manage queries Saved queries as sources that can also be queried Leads to potential for query networks. vSPARQL Service. RDF Store. vSPARQL Service. RDF Store. vSPARQL - PowerPoint PPT Presentation
Transcript of Integration architecture
Integration architecture
• Queryable sources that generate XML• Distributed queries over sources• Query Manager to manage queries• Saved queries as sources that can also be
queried• Leads to potential for query networks
vSPARQLService
RDF Store
vSPARQLService
RDF Store
vSPARQLService
RDF Store
QM DB
vSPARQLService
QM Server
QM Client
RDF Store
QM DB
vSPARQLService
QM Server
QM Client
RDF Store
XML
XML
BIRN fMRI Study
Label using Talairach Demon
Extract centers of activation
BIRN fMRI Study
Schizophrenics vs Healthy Controls
XML
QM DB
vSPARQLService
QM Server
RDF/OWL
XML
QM Client
RDF Store
QM DB
vSPARQLService
DXQueryService
QM Server
RDF/OWL
XML
QM Client
RDF Store
QM DB
vSPARQLService
DXQueryService
QM Server
RDF/OWL
QM Client
RDF Store
XML
QM DB
vSPARQLService
DXQueryService
QM Server
RDF/OWL
QEService
QM Client
RDF Store
XML
QM DB
vSPARQLService
DXQueryService
QM Server
RDF/OWL
QEService
QM Client
RDF Store
XML
QM DB
vSPARQLService
DXQueryService
QM Server
XML RDF/OWL
QEService
QM Client
RDF Store
XML
Region Filtered Healthy(Red)
Schizo-phrenic(Yellow)
Dorso_lateral prefrontalcortex
55 25 30
Brodmann area 6 213 107 106
Frontal lobe 575 288 287
N=1741
QM DB
vSPARQLService
DXQueryService
QM Server
QEService
QM Client
RDF Store
QM DB
RemoteServices
vSPARQLService
DXQueryService
OtherServices
QM Server
Other Client
XML RDF/OWL
XML
QEService
Other Client
QM Client
RDF Store
RDF/OWL
RemoteServices
RemoteServices
vSPARQLService
DXQueryService
OtherServices
Other Client
XML RDF/OWL
XML
Other Client
QM Client
RDF Store
RDF/OWL
RemoteServices
Query ManagerCore
RemoteServices
vSPARQLService
DXQueryService
OtherServices
Other Client
XML RDF/OWL
XML
Other Client
QM Client
RDF Store
RDF/OWL
RemoteServices
Query ManagerCore
Query Manager Core with Plugins
RemoteServices
Other Client Other
Client
RemoteServices
Query Manager
RDF/OWL
RDF/OWL
XML
XML
Query Manager
RDF/OWL
RDF/OWL
XML
XML
Query Manager
BIRN fMRI and FMA
BIRN fMRI FMA
Query Manager
BIRN fMRI, VBM and FMA
BIRN fMRI
FMA
VBM
Query Manager
Electronic Data Capture and Freezer Management
Freezer Management
EDC
Query Manager
Biorepositories
Biorepository
Biorepository
Query Manager
Human Studies Database
Clinical Trials Metadata
Clinical Trials Metadata
Ontology of Clinical Research
Query Manager
Ontology Views
Ontology
Query Manager
Summary
Issues
• Response time• Reliability• Security• Discoverability• Usability• Integration with other systems and methods
Query Manager
Query Manager Future Work
Query Manager
Query Manager
Query Manager
BIRN fMRI
FMA
Brain Imaging View
EDC
Clinical View
Clinical
Imaging
Clinical/Imaging View
Genomic View
Gene
Protein
Others….
Clinical/Imaging Genomic
Translational View
Query Web
Query Web
Translational Medicine
Web
Semantic Web
Internet
Query Web
A Network-centric view of information systems
Bin Zhang
A convergence?
• Biology as an information science• Information science as biology• Networks as the link
Credits
• Todd Detwiler• Onard Mejino• Joshua Franklin• Ron Shaker
• Xenia Hertzenberg• Nolan Nichols• Marianne Shaw• Wayne Warren
• Linda Shapiro• Dan Suciu• Cornelius Rosse
Funding: NLM, NIMH, NHLBI
