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HOW WEARABLE ELECTRONICS WILL CHANGE CLINICAL TRIALS?

ARTICLE FEATURED ON CLINICAL LEADER

Written by Glenn Keet, Chief Executive Officer at Clinovo,Marc Desgrousilliers,Chief Technology Officer at Clinovo

2© 2015 Clinovo. All Rights Reserved. The contents of this document are confidential and proprietary to Clinovo

Advances in sensor technology and microelectronics = new

opportunities for health and life sciences industries

Continuous bio-monitoring without manual intervention

Better data quality while lower costs and provider-patient

interaction

Wearable electronics market expected to reach $173.3

billion by 2020.

PROS

Improve Patient Monitoring

3© 2015 Clinovo. All Rights Reserved. The contents of this document are confidential and proprietary to Clinovo

Current wearables provide basic monitoring

1/3 of Fitbit owners stopped wearing it after 6 months

Issues with compliance, validation & clinical trials

CONS

Improve Patient Monitoring

4© 2015 Clinovo. All Rights Reserved. The contents of this document are confidential and proprietary to Clinovo

Apple Watch = Game Changer?

30 million units expected to be sold in 2015

Research Kit allowing clinical apps to be downloaded and

used by owners

Easier and cost effective solution

for patient recruitment

Improve Patient Recruitment

5© 2015 Clinovo. All Rights Reserved. The contents of this document are confidential and proprietary to Clinovo

mPower’s Parkinson’s App for the Research Kit:

7.406 patients enrolled after 6 hours

MyHeart Counts App (Stanford University’s cardiovascular clinical trial):

11.000 volunteers in one day (Usually takes a year to reach this level)

Improve Patient Recruitment

6© 2015 Clinovo. All Rights Reserved. The contents of this document are confidential and proprietary to Clinovo

Streamlining Data Collection Apple watch biosensors currently measure:

- Speech impairment- Hearing- Photographic evidence of health issues (Via iPhone)- Distance traveled (Via iPhone)

Can potentially measure:

- Skin Temperature- ECG- Galvanic Skin ResponseAnd Much More

- Heart Rate- Balance- Sleep Patterns- Gait- Activity Level)

Major changes in the patient-provider relationship

7© 2015 Clinovo. All Rights Reserved. The contents of this document are confidential and proprietary to Clinovo

Automating Patient Data Collection In 2012, FDA approved Proteus, an ingestible biosensor

Gives the ability to test body fluids without blood draw nor

lab analysis.

NASA introduced ingestibles with therapeutic capabilities

Examples of the convergence of drug, medical device, biosensors and Nano technologies

8© 2015 Clinovo. All Rights Reserved. The contents of this document are confidential and proprietary to Clinovo

Consumer biosensors adoption rate expected to grow

significantly

Advances in Nano and Cloud technologies also expected to

develop significantly

This combination will radically change clinical research,

improving patient recruiting and monitoring while lowering

development and therapy costs.

Conclusion

9© 2015 Clinovo. All Rights Reserved. The contents of this document are confidential and proprietary to Clinovo

Sources http://www.researchandmarkets.com/research/hgdx6p/wearable http://mobihealthnews.com/31697/survey-one-third-of-

wearable-device-owners-stopped-using-them-within-six-months/ http://bgr.com/2014/07/14/apple-iwatch-price-and-sales http://mendelspod.com/podcasts/gene-and-tonic-iwatch-and-

research-kit-23andme-goes-big-time-no-spaceship/ http://vancive.averydennison.com/en/home/technologies/

metria.html http://davidleescher.com/2012/09/04/five-reasons-why-proteus-

is-the-holy-grail-of-digital-health/

10© 2015 Clinovo. All Rights Reserved. The contents of this document are confidential and proprietary to Clinovo

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