HOW CELLS EXPORT

PROTEINS IN THE

MEMBRANE AND

RESEARCHERS VISUALIZA

OCURRING mRNA

María Camila Foronda

Campuzano

Medicine Student

FOLDING

FOLDING

INTRODUCTION

The structure of a ribosome complexinvolved in a protein process

By a wonderful technique they

vizualized mRNA and associated

molecules

How Cells Export And Embed Proteins In

The Membrane ScienceDaily (January 3, 2001)

How Cells Export And Embed Proteins In The Membrane

The

ribosomes found on

the RE fabric proteins

that are

export outside cell

The proteins move

from the ER and accu

mulated

near the Golgi appar

atus and

How Cells Export And Embed Proteins In The Membrane

The Proteins

are "eliminated"

from membrane

in vesicles by

channels

How Cells Export And Embed Proteins In The Membrane

• Transduction of external

signals produces a resp

onse from the target

cell

• This response is impaired

as a

result of activation or

inhibition of a metaboli

c pathway

How Cells Export And Embed Proteins In The Membrane

• An international team of researchers to find another

mystery related to the riboso

mes -

the enigmatic jumbles of

molecules

• the journal Nature, could help

in developing new

antibiotics to combat multi-

resistant superbugs such as MRSA(methicillin-

resistant Staphylococcus aure

us infection) found inmany U.S

. hospitals

ANOTHER

STUIDES…

OBSERVATION

Thisinvestigacionsraises that the

complexribosome-

protein and thereceptor act as a

«switch», so itcan stop

They raisesto that it more

studiesproductionsof proteins

can be controled

It couldindicated tothe stop of

manydeseases

In Scientific First, Researchers Visualize

Naturally Occurring mRNAScienceDaily (Jan. 19, 2011)

In Scientific First, Researchers

Visualize Naturally Occurring

mRNA• Messenger

RNA, the key

intermediary in

gene

expression, tra

nslating the

DNA's genetic

code into the

amino acids

that make upproteins

In Scientific First, Researchers

Visualize Naturally Occurring mRNA

• There

are 20 amino-

acids forming sub-

units for

proteins while

only four nucleic

bases are used to

construct the RNA

or DNA

In Scientific First, Researchers

Visualize Naturally Occurring mRNA

• The mature mRNA is transport

ed to the cytoplasm of the

cell, in the case

of eukaryotes beings through

nuclear membrane pores

Messenger RNA in

the cytoplasm is coupled to t

he ribosomes

In Scientific First, Researchers

Visualize Naturally Occurring mRNA

• mRNA are the machiner

y responsible for protein

synthesis.After a

certain amount of time

the mRNA is

degraded into its

component nucleotides

, usually with the

assistance of

ribonucleases

OBSERVATION

It is animportant

study becausethey are in theway to control

gene expressions

This control can cure

manydesease with

geneticorigin

It is a useful

techniqueto

monitoredmRNA

MEDICAL UTILITY

MEDICAL UTILITY

Both studies can

be very benefical

for discover

deseases and try

to find a cure for

it, because

molecular

biology is basis of

all functions of

our bodies

BIBLIOGRAPHY

• MARTINEZ S, Lina Maria. Biologia

Molecular. 6 ed. Medellin. UPB.

Fac Medicina, 2011. 34p.

• ScienceDaily, Your source for the

latests research news, United

States.[Index].