Hemodynamics In The Icu
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Transcript of Hemodynamics In The Icu
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HemodynamicsHemodynamicsDalhousie Critical Care Lecture
Series
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ICUObjectives
Discuss the basic cardiac physiology that is routinely used in the management of critically ill patients
Determinants of MAP Determinants of CO Determinants of DO2
Be able to describe the various states of shock using the above concepts.
Describe how and why we monitor CVP
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ICUEquations to Live By
MAP = CO x SVR CO = SV x HR
Therefore:
MAP = SV x HR x SVR
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ICUDeterminants of SV
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ICU The Need for Preload
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ICU Preload
JVPCVPRAPRVEDPPADPAWPLVEDPLVEDV
Estimates with error
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ICURight Atrial Waveform
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ICU
Looking Carefully at the JVP/CVP
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ICU
The Role of Afterload
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ICUAfterload paradigm
If CO increases with decreased afterload then wouldn’t the body work better with a very low afterload?
What pathologic condition is this called?
Video
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ICU
In the end why do we need CO?
It’s all about oxygen delivery to the tissues
DO2 is delivery VO2 is consumption CaO2 is arterial oxygen content CvO2 is venous arterial content
DO2 = CO x CaO2
VO2 = CO x (CaO2 – CVO2)
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ICU
What happens when VO2 > DO2?
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ICU
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ICU
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ICUAll of Cardiac Physiology
in a Nut Shell
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ICU
It’s Really All About the SvO2
Generally believed that it’s better to have a normal SVO2 than a lower one.
Early normalization of SVO2 as a goal of therapy is desired
The unknown:1. low SVO2 after the initial resuscitation
2. what number to treat and what to treat to3. conditions other than obvious shock
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ICU
What number to treat and what is “The Magic
Number”? The SVcO2 of 70% is
based on normal physiology
“Over treating” may result in increased mortality through a variety of mechanisms
Increased VO2
Oxidative injury It is suggested that the
ideal number is patient dependent and that we should be titrating to the inflection point on the curve rather than an absolute number
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ICU
1. 488 post operative CABG patients retrospective analysis to determine the prognostic cutoff number for SVO2 as it pertains to mortality
2. SVO2 < 55% at admission was the cutoff for significant mortality difference
3. As low SVO2 was aggressively treated the question of whether it was the number or the treatment that caused the increased mortality
The Magic Number
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ICU
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ICU
1. Retrospective cohort study of 111 critically ill patients with septic shock
2. Time spent below SVO2 of 70% was an independent predictor of mortality along with lactate, MAP and CVP
3. Supporting validation of Rivers septic shock algorithm
The Magic Number
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ICU
Using the Swan-Ganz catheter to diagnose type
of shock
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ICU
Condition HR MAP CO/CI CVP/RAP
PAP/PAWP Notes
Left ventricular failure
Cardiogenic pulmonary edema
N/ PAWP > 25mmHg
Massive pulmonary embolism
PAD>PAWP by >5 mmHg
Pulm Vasc Res
Acute venticular septal defect
giant ‘v’ waves on PAWP trace
O2 step up noted in SvO2
Acute mitral regurgitation giant ‘v’ waves on PAWP trace
Cardiac tamponade PAD/PAWP equalised
Right ventricular failure V
V PAP /N PAWP RVEDV
Hypovolemic shock O2 extraction + SVR
Cardiogenic shock O2 extraction + SVR
Septic shock O2 extraction + SVR
Using the Swan-Ganz catheter to diagnose type of shock
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ICUSummary
We use basic cardiac physiology in the ICU to:
1. Diagnose various states of shock2. Optimize tissue perfusion3. We will next talk about various drugs that
can be used to manipulate the parameters set out in these equations