Hcg and hpl
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Transcript of Hcg and hpl
PLACENTAL HORMONES HCG AND HPL
@copyright and owner POKHREL,BHARAT
DOCTOR OF MEDICINE
PLACENTA
l FOETAL ORIGIN → CHORION FRONDOSUM l MATERNAL ORIGIN → DECIDUA BASALIS
HORMONES
PROTEIN HORMONES STEROID HORMONES
l hCG l hPL l hCT l Hypothalamic and
pituitary like hormones l Others like inhibin, relaxin
and beta endorphins
l Esrogens l Progestin
HCG (Human chorionic gonadotropin)
HPL (Human placental lactogen)
1)It is a hormone produced by the syncytiotrophoblast, a portion of the placenta following implantation
2)The pituitary analog of hCG, known as luteinizing hormone
3)promotes the maintenance of the corpus luteum during the beginning of pregnancy
4) hCG can also be used clinically to induce ovulation in the ovaries as well as testosterone production in the testes.
1)Also called human chorionic somatomammotropin (HCS), is a polypeptide placental hormone.
2)Its structure and function is similar to that of human growth hormone
3)↓ maternal insulin sensitivity leading to an increase in maternal blood glucose levels.
4)↓ maternal glucose utilization, which helps ensure adequate fetal nutrition (the mother responds by increasing beta cells). Chronic hypoglycemia leads to a rise in hPL.
Picture taken from : http://www.slideshare.net/NadaGYoussef/lecture-4-development-inheritance
PRODUCTION OF HCG