Hawler Medical University - HMU College of Pharmacypha.hmu.edu.krd/Portals/0/4th Med Chem- BioPha...

1

Hawler Medical University

College of Pharmacy

Dept. of Medicinal Chemistry

Course Book

Medicinal Chemistry 4th Year

Course Coordinator:

Dr. Muhammad Hassan Muhammad

Assistant Profesor

Medicinal Chemistry

Course Coordinator and list of teachers

1. Name of the course : Medicinal Chemistry 4th

year

2. Lecturer in charge: Dr Muhammad H. Muhammad

3. Department: Pharmaceutical Chemistry

4. Contact :

Address: Hawler Medical University

College of Pharmacy / Dept. of Pharmaceutical Chemistry

Email: [email protected]

Website link: www.pha.hmu.edu.iq

5. Participant lecturers :

1. Dr. Nuhad A. Al Omari

2. Assistt Lecturer : Hayman S. Abdulrahman

mailto:[email protected]

http://www.pha.hmu.edu.iq/

2

Course Overview

Organic medicinal and pharmaceutical chemistry will deal with topics important

for understanding and appreciating the chemistry and properties of medical

substances of heterocyclic and polycyclic structures. The course covers material

related to properties, nomenclature and pharmaceutical importance the principle

and theory of structure activity relationship are also covered with emphasis on

optical, geometrical and conformational isomerism.

In addition this course is designed to incorporate a number of experiments for the

synthesis of certain drugs which are included in the theoretical course of organic

medicinal and pharmaceutical chemistry. The experiments are intended to train the

undergraduate pharmacy students to use different chemical reactions and various

analytical methods for preparation and assay of some representative drugs of

different classes and also to meet the students need for a concise skill on practical

organic medicinal and pharmaceutical chemistry.

Course Objectives

The discipline of medicinal chemistry is devoted to the discovery and development

of new agents for treating disease. The aim of this course is to study the

relationship between drug chemistry and pharmacological action so that translate

the drug structural formula into therapeutic effect. In addition concentrate on the

methods of preparation of some pharmaceutical agents, therefore supply

pharmacists and other medical faculties with broad area of knowledge about drugs

in order to treat disease and look for further researches in this field.

3

Course Reading List:

1. Text Book – Wilson and Gisvold's Organic Medicinal and Pharmaceutical

Chemistry, edited by Delgado and W. A. Remer's, 11th

edition (2004)

2. Reference – Medicinal Chemistry by Ashutosh Kar

3. Introduction to medicinal chemistry by Alex Gringauz

Syllabus:

1. Course title: Medicinal Chemistry 4th year

2. Number of credits 8: 3hr theory 3hr practice (2 semester = 30 weeks)

The course complies the following:

Adrenergic Agents:

- Adrenergic receptor agonists

- Adrenergic receptor antagonists

Cholinergic Agents

- Cholinergic receptor agonists

- Cholinergic receptor antagonists

CNS Depressants

- General anesthetics

- Sedative hypnotics

- Anxiolytics

- Anticonvulsants

- Antipsychotics

CNS Stimulants

- Analeptics

- Xanthine alkaloids

- Sympathomimetic CNS stimulants

- Antidepressant (MAO and TCA)

- Psychedelics

Chemotherapeutic Agents:

- B-lactam

- Aminoglycosides

- Tetracyclines

- Lincomycins

- Polypeptides antibiotics

Antineoplastic Agents:

4

- Alkylating agonists

- Antimetabolites

- Antibiotics and plant products

Antiviral Agents:

- Agents act on DNA viruses

- Agents act on RNA viruses

Analgesics

- Morphine and related agents

- Antitussive agents

- Nonsteroidal anti-inflammatory agents

Assessment (grading): summative assessment:

First semester: 20%

Second semester: 20%

Final exam: 60%

Outline of course:

Subject Lecturer No. of hrs

1- CNS Depressants: Muhammad H. Muhammad

Nuahad A. Al omari

Hayman S. Abdulrahman

12

General anesthetics 2

Sedative hypnotics 3

Anxiolytics 2

Anticonvulsants 2

Antipsychotics 3


2- CNS Stimulants: Muhammad H. Muhammad

Nuahad A. Al omari


13

Analeptics 2

Xanthine alkaloids 2

Sympathomimetic CNS stimulants 2

Antidepressant: Mono Amine Oxidase Inhibitors

2

Antidepressant: Tricyclic

antidepressant 3

Psychedelics 2

5


3- Antiviral Agents: Muhammad H. Muhammad

Nuahad A. Al omari


10

Agents act on DNA viruses 3

Agents act on RNA viruses 7


4- Analgesics: Muhammad H. Muhammad

Nuahad A. Al omari


14

History of Analgesics 1

Pain 1

Morphine and related agents 6

Antitussive agents 1

Nonsteroidal anti-inflammatory agents 5


5- Adrenergic Agents: Muhammad H. Muhammad

Nuahad A. Al omari


10

Adrenergic receptor agonists 5

Adrenergic receptor antagonists 5


6- Cholinergic Agents Muhammad H. Muhammad

Nuahad A. Al omari


10

Cholinergic receptor agonists 5

Cholinergic receptor antagonists 5


7- Chemotherapeutic Agents: Muhammad H. Muhammad

Nuahad A. Al omari


11

B-lactam 5

Aminoglycosides 2

Tetracyclines 1

Lincomycins 1

Polypeptides antibiotics 2


8- Antineoplastic Agents: Muhammad H. Muhammad

Nuahad A. Al omari


10

Alkylating agonists 3

Antimetabolites 3

Antibiotics and plant products 4

6

Practical Syllabus 90 hr.

3 hr / week 1- Introduction 3

2- Preparation of acetylsalicylic acid 3

3- Determination of Aspirin using Back titration 3

4- Assay of methyldopa tablet using non-aqueous titration 3

5- Determination of Vitamin-C in effervescent tablets 3

6- Determination of sulfanilamide using Diazometric titration 3

7- Assay of Bromhexine tablet using UV-Spectrophotometer 3

8- Synthesis of paracetamol 3

9- Assay of paracetamol tablets 3

10- Identification and assay of PABA using diazotization reaction 3

11- Preparation Sulfonamides 3

12- Preparation of Aniline 3

13- Preparation of acetanilide 3

14- Chlorosulfonation and amination of acetanilide 3

15- Assay of levamisole using potentiometric titration 3

16- Identification of Griseofulvin by HPLC-technique 3

17- Assay of Aminophylline tablets 3

18- Assay and identification of Cimetidine 3

19- Assay and identification of Omeprazol 3

20- Assay and identification of Allopurinol 3

21- Assay and identification of cardiac glycoside (digoxin) 3

22- Assay and identification of Nystatin 3

23- Assay and identification of Streptomycin 3

24- Assay and identification of Doxycycline 3

25- Identification of prednisolone using fluorescence phenomenon 3

26- Assay and identification of Naproxen 3

27- Assay and identification of Ibuprofen 3

28- Determination of acyclovir using potentiometric titration 3

29- Preparation of amyl nitrite 3

30- Preparation of DDT 3

7

Student's Feedback on the Subject

Date: Course: Year: Lecturer/tutor No. Evaluation Question Subject's

Level 1-5 Subjective Remarks

1 The objectives and key massages of the subject were clear

2 The contents of the subject of the were useful and related to

the main objects of the course

3 The material were prepared carefully as needed

4 The lecturer/tutor while lecturing tried to analyze the

principles, contents and the important points of the subject

simply and properly.

5 The lecturer/tutor while lecturing kept my attention.

6 The lecturer/tutor came into the classroom on time and was

committed to the duration of the lecture.

7 The lecturer's behavior in the classroom was clam and respectful

8 The slides used in the lecturer were clear and attractive

9 At the end of the lecture, the lecturer gave the students a

chance for question and comments. His/her answers were complete

10 The reading sources are new and compliable with the

subject.

Total of the level

Students to evaluate the level of the contents

1 2 3 4 5

Poor Accept Medium Good Very good


Date: Course: Year: Lecturer/tutor No

.

Evaluation Question Subject's

Level 1-5

Subjective

Remarks


2 The contents of the subject of the were useful and related to the

main objects of the course


4 The lecturer/tutor while lecturing tried to analyze the principles, contents and the important points of the subject



6 The lecturer/tutor came into the classroom on time and was committed to the duration of the lecture.

7 The lecturer's behavior in the classroom was clam and

respectful



chance for question and comments. His/her answers were

complete

10 The reading sources are new and compliable with the subject.

Total of the level


1 2 3 4 5


8


Date: Course: Year: Lecturer/tutor N

o.


Level 1-5

Subjective

Remarks


2 The contents of the subject of the were useful and related to

the main objects of the course


4 The lecturer/tutor while lecturing tried to analyze the principles, contents and the important points of the subject



6 The lecturer/tutor came into the classroom on time and was committed to the duration of the lecture.


respectful



chance for question and comments. His/her answers were

complete


Total of the level


1 2 3 4 5


Examinations:

- The exams will be held during the course.

- Quizzes – during the practical hours.

- Theoretical exams: one per semester.

- Practical exams: one or two per semester.

- Final exam – Theoretical, Practical and Oral.

Theoretical: exams will be mixed

- MCQ. (Multiple choices questions)

- SCQ. (Single choices Questions)

- Short Essays

- Diagrams

Practical exam:

- Practical related Questions

- Theoretical related Questions

- Assay of unknown drug

- Identification of unknown drug

On Answering: the student should

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- Read the question carefully

- Think carefully before answering

- Plan your answering

- Answer should contain preface , content and conclusion

- Answer should be precise and to the point

Samples of the expected questions and their answers:

*MCQ – sample:

In the Becket hypothesis (for proper binding):

- (T) a – Tertiary nitrogen is required.

- (T) b –Central carbon is essential.

- (T) c – Phenyl ring attached to central carbon is needed.

- (F) d – The central carbon should be far from tertiary nitrogen by three carbon atom

*SCQ – sample

- All following are morphine related analgesics except:

A – Dextromethorphan

B – Diphenoxylic acid

C – p-chloroisobutyric acid

D – Naltrexone

- Short essays

Give a short account on SAR of phenothiazines

Student's Feedback on the Course

Date: Course: Year: Lecturer/tutor No. Evaluation Question Subject's

Level 1-5

Subjective

Remarks


2 The contents of the subject of the were useful and related to the main objects of the course

3 The coordinator teacher had worked hard to cooperate and prepare the

material

4 The coordinator teacher had worked hard to cooperate and prepare the course

5 The lecturer were carefully selected and were expert in their field

6 The coordinator teacher gave a good attention to the student's criticism

and claim

7 Information on the Examination process was well provided

8 The questions of the exam were related to the content of the course

9 Total of the level

10 There is a potential to promote and develop the course in the following

areas:


1 2 3 4 5


10

Biopharmaceutics and

Pharmacokinetics

Course Name: Biopharmaceutics and Pharmacokinetics

Course Level Year: Fourth Class Credit Hour(s): 2 hours

Course Coordinator: Dr.Jafar tememe

Lecturer: Dr.Asos & M. Feras Majid

Topics:

First Semester

Subject Hours

1. Introduction to Biopharmaceutics 2

2. Bioavailability

Introduction to Bioavailability

Mechanism of drug absorption

Factors that affect the bioavailability of drug after oral

administration.(physiological factor, physicochemical factors and type of

dosage form )

8

3.Mechanism of drug absorption 4

4. Supply to the gastrointestinal fluids with drug..

Dissolution and release of drug from gastro-intestinal tract. (in vitro and

in vivo)

6

5.Drug absorption study by various route of administration 10

Second Semester Introduction to pharmacokinetic

One compartment model drug

2

11

Two compartment mode

Pharmacokinetic of drug absorption

Zero- order absorption model

first- order absorption model

k elimination

half – life estimation

4

Distribution of drug in the body

Apparent volume of distribution.

Transport of drugs through specific membranes

4

Renal and hepatic clearance

The concept of clearance

Renal clearance

Hepatic clearance

6

Protein binding 2

Multiple- dosage regimen

Drug accumulation and how the drug reach to plasma concentration

steady state

6

Multiple- dosage regimen

Intravenous infusion

Repetitive intravenous injection.

Loading dose

Repetitive oral dosing

4

Non linear pharmacokinetics 2

Textbook(s):

Applied biopharmaceutics and pharmacokinetics (Ed. Leon shargel and

Andrew B. C. Yu)

12

Practical Course (second course)

Pharmacokinetic Lab

Preparation of calibration curve of drug with application of statistics 6

In vitro dissolution test 6

In vitro evaluation of antacids 3

In vitro evaluation of bulk forming laxatives 3

pH and solvent effects of drug solubility 6

Biological membrane permeation of concentration gradient 3

Mathematical review of pharmacokinetic 6

Determination of pharmacokinetic parameters from plasma data 6

Determination of pharmacokinetic parameters from urine data 6

References:

Practical Biopharmaceutics and pharmacokinetics Laboratory Manual

(University of Baghdad / College of Pharmacy)

13

Public health I. Course

Coordinator and list of teachers

1. Course information:

Course title: Public health

Credit hours: 2 hours

Prepared by: Dr. Samir Mahmood Othman

Lecturer in charge : Dr. Samir Mahmood Othman

Dept. : Clinical pharmacology

2. Contact :

Address:

Hawler Medical University/ College of Medicine/ Dept. Community Medicine

Email: samir.othman @ hawlermu.org

[email protected]

Participant lecturers: None

3. Class time and place:

Days and time: Saturday 9:30-11:30 am.

Class location: Hall no. 3/ College of Pharmacy.

II. Course description:

1. Course Objectives

In the course, you will also have an introduction to the public health concept and epidemiology

and its benefit in medicine science and its applications during conducting medical researches in

the future.

You will also have an introduction to the primary health care that would teach the students how

they deal with patients at level of primary health care centers and teach them the principles and

elements of primary health care.

The course also covers an introduction to the communicable and non-communicable diseases

and it emphasizes on risk factors, prevention and control.

2. Course outcomes

1. Knowledge and understanding:

a. Understanding the concept of public health.

b. Understanding the concept of preventive medicine.

c. Understanding the principles and elements of primary health care in the

community.

2. Intellectual skills:


14

a. Differentiate between curative and preventive medicine

b. Choosing appropriate strategies in prevention and control of certain

communicable and non-communicable diseases in the community.

3. Subject specific skills:

a. Active participation in enhancement of individuals‟ health in the society

b. Proper use of essential drugs.

c. Have been learned how infant vaccination schedule applied in our region.

4. Transferable skills:

a. Transfer the concept of „‟preventive is better than cure‟‟ to the community.

b. Active participation of students in health education.

3. Course policies

i. Class attendance;

Students are expected to attend all classes of this course (without exception). A prior

approval is required for class absence except for emergencies. However, any student

with 30% short attendance will be enforced to withdraw from the course.

ii. Tardy:

Do not come late to class. Any student coming late will not be allowed to attend the class

and he/ she will marked absent.

iii. Exam:

Failure in attending a course exam will result in zero mark unless the student provides an

excuse acceptable to the Dean who approves a re-sit exam. Failed courses will normally

be reassessed in the scheduled semester. It is your responsibility to attend the exam at the

correct time and place.

iv. Exam attendance/ punctuality:

In the event that a student is up to ten minutes late, he/ she will be permitted to attend/ sit

the exam. However, there will not be any extra time allowances made in favor of this

student.

In the event that a student is more that 10 minutes late, he/ she

will not be permitted to attend the exam.

v. Re-sit exams:

The student will not be allowed to re-sit an exam unless he/ she furnishes the College

with a written evidence as follow:

1. Sickness by providing a medical report stamped by the Ministry of Health.

2. Death of a member of his/ her family.

3. Accidents (e.g. car accident)

4. Natural causes such as heavy rainstorms.

15

vi. Cheating:

Cheating is an attempt to gain marks dishonestly and includes:

1. Copying from another student‟s work.

2. Using material not authorized by the institute.

3. Collaboration with another student during a test, without permission.

4. Knowingly using, buying, selling, or stealing the contents of a test.

5. Plagiarism which means presenting another person‟s work or ideas as one‟ own,

without attribution.

vii. Penalty of cheating:

The minimum penalty for cheating is an automatic Zero for the test or assignment leading

to a possible “F” for the subject. The student will be expelled from the examination room

so that he/ she doesn‟t disturb other students. The exam invigilator will produce a report

on the case. The report will be kept in the student file. A second offense will result in the

immediate suspension of the student for the remainder of the current semester. A copy of

the decision will be kept in the student file, while another one will be passed to the Dean.

viii. Mobile phones, palm personal computers (PCs) and anything related

to the subject of exam are not allowed in classes during examinations.

III. Course Reading List:

1. Park K. Park‟s textbook of preventive and social medicine. 16th ed. Jabpur, India,

Banaridas Bhanot, 2005

2. Heymann DL. Control of communicable diseases manual. 17th ed. Washigton.

American Public Health Association , 2004

3. Brett J. Cassens. Preventive Medicine and Pblic Health. 2nd

ed.London,Williams

& Wikins, 1992

IV. Methods of instruction:

The methods of instruction may include, but are not limited to: lectures

V. Assessment (grading):

1. Passing grade:

A grade of 50 is the minimum passing grade for this course. Grades less than 50 are not

acceptable for credit towards graduation in this course.

16

2. Elements of final grades:

Elements Weight

1. Mid-term theoretical exam: 15 %

2. Quizzes and assignments:

3. Semester theoretical exam:

10 %

15

4. Final exam: 60 %

Total: 100%

90% - 100% = EXCELLENT

80% - 89% = VERY GOOD

70% - 79% = GOOD

60% - 69% = MEDIUM

50% - 59% = FAIR

< 50 % = FAIL

Outline of the course:

Topics

Public health concept (6 hours)

History of public health

Definition and spectrum of health

Concepts and spectrum of disease

Concepts of causation

Concepts of control

Definition and dimensions of public health

Preventive medicine and levels of prevention

Fundamentals of Social medicine

Community medicine and its main subjects

Principle of epidemiology (2 hours)

Definition & aim of epidemiology

Herd immunity

Primary Health Care (4 hours)

Definition

Principles

Elements

Maternal and Child health (MCH)

Host and Defense Mechanism (Vaccination)

Immunization Schedule in Kurdistan Region

Essential Drugs

Drug Misuse

School Health Services

17

Occupational Health Services

Environmental Health (2 hours)

Air pollution

Water Quality Control

Waste Disposal

Communicable Diseases Control (4 hours)

Viral Hepatitis

Influenza types

- Avian flu

- Swine flu


Date: Course: Year: Lecturer:

N

o.


Level 1-5

Subjective

Remarks


2 The contents of the subject were useful and related to the main objects of the

course


4 The lecturer tried to analyze the principles, contents and the important points of the subject simply and properly.

5 The lecturer kept my attention.

6 The lecturer usually on time and committed to the duration of the lecture.


9 At the end of the lecture, the lecturer gave the students a chance for question

and comments.


Total of the level


1 2 3 4 5


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Pharmacology Syllabus of Pharmacology (practical)

fourth year stage, first semester

Laboratory Subject

1. 1- General instruction about working in laboratory

2- handling of animals and dose calculation

2. Antagonism and antagonicity.

Evaluation of effects of pilocarpine on isolated tissue of a piece of a rabbit.

3. Review, tutorial and discussion

4. Evaluation of β-blockers (atenolol and propranolol) and adrenaline effect on a piece of

tissue of rabbit jejunum.

5. Comparison between the effects of chlorpromazine and propranolol on blood pressure

(BP) and heart rate (HR).


7. Effects of pancuronium and acetylcholine..an attempt to clarify concepts on muscarinic

and nicotinic receptors

8.

Effects of calcium cation and calcium channel blockers on the piece of rabbit jejunum-

isolated tissue.. an attempt to clarify role of calcium ion in vasoconstriction and in

tetanus


10. Evaluation of the effects of probantheline on the piece of rabbit jejunum-isolated tissue.

11 Evaluation of carbamate compounds as indirect reversible cholinergic drugs..and

clarifying role of cholinesterase activator drugs.


Q- Talk briefly about the types of antagonisms.

Answer:

There are three types of antagonisms:

1- Physiological antagonism, e.g., adrenaline that antagonize biological action of histamine.

2- Pharmacological antagonism, e.g., ondansetrone that antagonize action of serotonine at

the site of action:5-HT3 receptor

3- Chemical antagonism, e.g., antacid drugs that antagonize and neutralize action of

hydrochloric acid in the stomach.

19


College of Pharmacy

Depretment of Pharmacology and Toxicology

Course Book

Toxicology 4th Year

Course Coordinator and list of Teachers

1. Name of the course: Toxicology 4th year

2. Lecture in charge: Dr. Ansam N. Al-Hassani

3. Department: Pharmacology and Toxicology

4. Contact: Hawler Medical University

Collage of Pharmacy – Department of Pharmacology and Toxicology

Email: [email protected]

Website link: www.hawlermu.org

5. Participant lecturers:

Dr. Ansam N. Al-Hassani

Course Overview

To develop an understanding concerned the mechanism of toxicity of many drugs and

compounds on human body and produce their toxic or cell health.

Course Objective The students will have basic understanding of the toxic and side effect due to misuse of drugs

and chemicals in which we are contact with. Also understanding the environmental toxicity (car,

water, and soil), industrial toxicity (metals, alkali and acids), and the major sign and symptoms

of toxicity and how we can protect or treat them.

Course Reading List

Cassarett and Doulls, Toxicology, 6th Ed., Curtis S. Klassan, 2001, McGraw H.

http://www.hawlermu.org/

20

Syllabus

1. Course title: Toxicology 4

th year.

2. 3hr. theory and 3hr. practice.


Classification, scope of toxicology, environmental toxicology, factor that modify drug toxicity,

testing for toxicity.

Course Participants: 4th year pharmacy students.

Instructors:

Dr. Ansan N. Al-Hassani

Course length 15 weeks (semester program)

Teaching methods- Theory (power point presentation) / practical (experiments)

Assessment (grading): summative assessment.

2nd

semester 40%

Fina

Outline of Course

Subject Lecturer No. of hrs.

Number in Toxicology

Classification of Toxic Agents

History of toxicology

Areas of toxicology

Risk and safety

Spectrum of toxic dose

Routes and sites of exposure

Characteristics of exposure

Duration and frequency of exposure

Characterization of the toxicity of any agents

Spectrum of undesired effects

Dr. Ansam 3

Dose-response Relationship

Accepts

Characteristics

Type of D-R curves

Uses of D-R

How to obtain D-R

1

Statistical concept and LT-50

LD-50: Definition and determination

Standard deviation

Standard error of the mean

Variance students t-test

1

21

Environmental Toxicology

Solvent and vapors

Pollution (Air and solid)

Pesticides, insecticides, herbecides, rodenticides,

insecticides of botanical origin

Metals

Forensic toxicology

Clinical toxicology-food poisoning (bacterial toxins)

plant toxins

household

poisoning

2

1

4

2

2

2

1

1

Systemic Toxicology

Liver toxins

Renal toxins

Blood toxins

Eye toxins

Skin toxins

Respiratory toxins

9

Factor that Modify Toxicity

ADME

Biological (biotransformation)

Genetic

6

Testing for Toxicity

Acute, sub-acute and chronic toxicity

Reproduction and teratogenicity

Mutagenicity

Carcinogenicity

Protocol of antidote

Food additives

6

Reference Books: Cassarett and Doulls, Toxicology, 6

th Ed., Curtis S. Klassan,

2001, McGraw H. Pub.

22


College of Pharmacy

Dept. of Pharmacognosy

Course Book Community Pharmacy 4

th Year

Course Coordinator:

Dr. Alaadin Naqishbandi

Community Pharmacy

Course Coordinator and list of lecturers

5. name of the course : Community Pharmacy 4th year

6. Lecturer. in charge : Dr. Alaadin Naqishbandi

7. Dept. : Pharmacognosy

8. Contact :

9. Address: Hawler Medical University

10. College of Pharmacy/ Dept. of pharmacognosy

11. Email : [email protected]

12. Website link: www.hmu.edu.iq

6. Participant lecturers :

1. Talar Ahmed mirza

2. Amanj I. Baker


23

Course Overview : Community Pharmacy allows students to enhance their ability to provide pharmaceutical care to

patients in a community pharmacy setting. Pharmacotherapeutic knowledge and clinical skills

are integrated with routine medication dispensing activities. The primary focus is patient

assessment, counseling and education, medication therapy and disease state management, and

documentation of patient information and interventions. During the course, the student will be

exposed to the clinical activities of the community pharmacy setting, with the focus placed upon

a patient care approach. The student will learn the goals of clinical intervention and the steps

necessary to effectively execute those interventions. Evaluating and solving drug related

problems, patient interaction, and acting as a primary health care source will be stressed. The

course introduces students to non prescription medications and their appropriate use. Students

will gain skills in assessing the patient‟s physical complaints and signs/symptoms, determining

conditions that require medical attention versus self-treatment, aiding in the proper selection of

product, advising about appropriate use of products, and monitoring nonprescription drug

therapy. An overview of pathophysiology, etiology, signs and symptoms, treatment approach

including, patient counseling, is presented.

The course is theoriticall. By the end of course the student will be able to get knowledge wether

patient can be managed by the pharmacist (give drug of choice) or should be referred to the

physician.

Course objectives Course Objective

Establish, maintain, and utilize patient histories and profiles in order to monitor and evaluate drug

therapy as well as identify, prevent, and resolve drug-related problems.

Interview, counsel and educate patients in an effective and professional manner.

Communicate with various health professionals in an effective and professional manner.

Document patient information and interventions.

Search, gather, and evaluate information from appropriate sources to answer drug information

questions.

Perform basic physical examination of a patient (e.g., blood pressure and heart rate measurement,

blood glucose testing).

Evaluate patient subjective and objective information to appropriately manage patients‟ drug therapy

and health problems/disease states.

Develop effective communication skills (written and oral) with patients, pharmacy staff, and health

care professionals

Educate patients about disease state goals,and demonstrate appropriate physical assessment skills

Course Reading List:

1.Text Book – Community pharmacy (symptoms, diagnosis, and treatment) (Ed. Paul Rutter)

24

Syllabus: 1. Course title: community pharmacy4

th year.

2. Course number 1/ number of credits2: 2hr theory .


- introduction

-Respiratory system

- Ophthalmology

- Women health

- Paediatric

- Dermatology

-Otic conditions

-Gastroenterology

-OTC diet/ weight control

3.Course Participants 4th year pharmacy students.

5. Course length 15 weeks (1 course program/year )

6. Teaching methods – Theory (power point presentation) presentation, case study)

Assessment (grading): summative assessment:

Mid term theoretical ( 40%)

Final term theoritical ( 60%)

Outline of course:

Subject Lecturer No of hrs

1. introduction 2

Communication skills approaches to

differential diagnosis key steps in the process

-formulating a diagnosis based on the patient and the initial

presenting complaint. –asking questions -confirm facts


2.Gastroenterology 8

Mouth ulcer oral thrush

gingivitis dyspepsia

2

Diarrhoea constipation 2

Irritable bowel syndrome haemoorrhoid 2

Abdominal pain , appendicitis 2

25


3. Respiratory system 4

General overview of R.T. anatomy history taking

and physical examination cough , common cold , sore

throat

2

Rhinitis , influenza , sinusitis self

assessment

2


4. Ophthalmology 4

General overview of eye anatomy

History taking and eye examination

2

Red eye , eye lid disorders , dry eye Self assessment 2

Subject Lecturer No of

hrs

5. Women health History taking

Cystitis

Vaginal discharge

Primary dysmenorrhoea (PD)

2


6. Paediatric history taking

head lice , thread worm, colic

2


7. otic conditions General

overview of ear anatomy history taking

and physical examination ear wax impaction

otitis externa

2


8. Dermatology 4

26

General overview of skin anatomy

Psoriasis

Dandruff

Seborrhic dermatitis

2

Fungal infection

Acne vulgaris

Eczema and dermatitis

2


9. OTC diet/ weight control 2

Student's Feedback on the Subject Date: Course: Year: 2013-2014 Lecturer/tutor

No

.


Level 1-5

Subjective

Remarks 1 The objectives and key massages of the subject were clear

2 The contents of the subject of the were useful and related to the

main objects of the course


4 The lecturer/tutor while lecturing tried to analyze the principles,

contents and the important points of the subject simply and

properly.




7 The lecturer's behavior in the classroom was clam and respectful


9 At the end of the lecture, the lecturer gave the students a chance for

question and comments. His/her answers were complete


Total of the level


1 2 3 4 5


27

Student's Feedback on the Subject Date: Course: Year: 2013-2014 Lecturer/tutor

No. Evaluation Question Subject's

Level 1-5

Subjective

Remarks 1 The objectives and key massages of the subject were clear

2 The contents of the subject of the were useful and related to the main objects of the course


4 The lecturer/tutor while lecturing tried to analyze the

principles, contents and the important points of the subject simply and properly.





respectful


9 At the end of the lecture, the lecturer gave the students a chance for question and comments. His/her answers were

complete

10 The reading sources are new and compliable with the

subject.

Total of the level


1 2 3 4 5


Examinations: The exams will be held during the course.

Quizzes

Theoretical exams: one per semester.

Final exam – Theoretical

Theoretical: exams will be mixed

MCQ. (Multiple choices questions)

SCQ. (Single choices Questions)

Short Essays

Case evaluation

True , false

On Answering: the student should

read the question carefully

Think carefully before answering

Plan your answering

Answer should contain preface , content and conclusion

Answer should be precise and to the point

Hawler Medical University - HMU College of Pharmacypha.hmu.edu.krd/Portals/0/4th Med Chem- BioPha...

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