Hallucinogenic Agent

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    HALLUCINOGENIC AGENT

    Hallucination is a false sense perception

    without any external object or stimulusto produce it. They are purely imaginary,and may affect any or all the specialsenses.

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    HALLUCINOGENIC AGENT

    CAUSE HALLUCINATION

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    TYPES OF HALLUCINATIONS

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    CLASSIFICATION OF

    HALLUCINOGENIC AGENT

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    INDOLE AMINES

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    HALLUCINOGENSA. LSD

    B. PEYOTE

    C. MESCALINE

    D. PHENCYCLIDINE (PCP)

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    A.LSD

    LSD, chemically known as lysergic acid diethylamide, is

    synthesized from rye ergot. It is tasteless, odourless, and

    the most potent, widely used hallucinogenic drug, havinga powerful effect in minute doses. It is available in the

    form of clear liquid, thin squares of gelatin, and pills of

    varying size and colours. It is usually taken on a sugar

    cube or by putting a drop on a blotter paper and licking it

    when the drug effect is desired. Thin squares of gelatinand clear liquid can be put in the eyes, and the pills can be

    eaten.

    HALLUCINOGENS

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    B.PEYOTE

    Peyote is obtained from a variety of cactus (peyotol)

    plants. It is available in the form of hard brown

    discs, tablets, and capsules. It can be chewed.Swallowed, taken in tea, or smoked. It is not as

    potent as LSD. It is used by tribal Indians of the arid

    regions for their religious ceremonies

    HALLUCINOGENS

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    C.MESCALINE

    Mescaline is another hallucinogen derived from

    the peyotol plant. Its availability, use, and effects

    are similar those of peyote.

    HALLUCINOGENS

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    D.PHENCYCLIDINE (PCP)

    Phencyclidine (PCP, angel dust, killer weed) is

    available in the form of liquid, white crystalline

    powder, capsules, and pills. It can be taken orally,smoked, and injected

    HALLUCINOGENS

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    HALLUCINOGENS

    Symptoms and signs of use: unusual hilarity, emotional

    swings, hallucinations, suspiciousness, bizarre behavior,

    synaesthesia, nausea, vomiting, widely dilated pupils,

    insomnia, tremors, vertigo, headache, psychotic reactions,

    bad trips, flash-backs.

    Fatal dose & period: uncertain, Not Known

    Treatment: Limit stimulation, tranquilizers, symptomaticmeasures, psychotherapy.

    Medicolegal aspects: Accidental, Suicidal, Homicidal, Habit

    forming

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    CANNABIS INDICA

    Also known as cannabis sativa or Indian hemp in India, Dagga

    in South and Central Africa, and hashish in Egypt, this plant

    grows all over India, and all its parts are poisonous. Itscultivation is restricted by law. The active principle is not an

    alkaloid but a fat soluble oleoresin, cannabinol

    (tetrahydrocannabinol-THC).

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    TYPES OF CANNABIS INDICA

    The following four forms.

    BHANG M AJUN GANJA

    CHARAS

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    BHANG

    Also known as sidhi, patti, or sabji., it is prepared from the

    dried leaves and fruit shoots which are used as an infusion

    in the form of a beverage. It contains the active principlein a concentration of 15% and is the least potent.

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    MAJUN

    This is a sweetmeat made with bhang. It produces

    grandiose delusions, in addition to all the effects of bhang

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    GANJA

    This consists of the following tops of the female plant,

    specially grown so that there is a large amount of resinous

    exudates. It contains the active principle in aconcentration of about 25 per cent. The resine has a rusty

    green color and characteristics odour.

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    CHARAS

    Also known as hashish, it is the resinous exudates from

    the leaves and stems of the plant. It is of dark green or

    brown color. It is smoked with tobacco in a pipe ofhookah and is the most potent of all cannabis

    preparations, containing the active principle in a

    concentration varying between 25-40 per cent.

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    CANABIS INDICA

    Symptoms and sign: Toxic preparation are: bhang,majun, ganja, and charas. Euphoria, visual, hallucinations,

    drowsiness, deep sleep, coma. In chronic poisoning,

    wekness, moral and mental deterioration, loss of sexual

    power, insanity.Fatal dose & period: 10gms of bhang, 8gms of ganja, and

    2 gms of charas per kg body weight, 12 hrs.

    Treatment : gastric lavage. Saline purgatives. Intravenous

    fluids. Oxygen and artificial respiration. Tranquilizers.Gneral measures.

    Medicolegal aspects: accidental stupefying for roadside

    robbery, kidnapping , and rape. Running amok. Addiction

    problems.

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    MECHANISM OF ACTION

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