Guia de Vacunacion en Usa 2013
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Transcript of Guia de Vacunacion en Usa 2013
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7/28/2019 Guia de Vacunacion en Usa 2013
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2 MMWR / February 1, 2013 / Vol. 62
Each year, the Advisory Committee on Immunization Practices(ACIP) reviews the current recommended immunizationschedules for persons aged 0 through 18 years to ensure thatthe schedule reflects current recommendations for licensedvaccines. In October 2012, ACIP approved the recommended
immunization schedules for persons aged 0 through 18 years for2013, which includes several changes from 2012.
Health-care providers are advised to use both the recommendedschedule and the catch-up schedule (Figures 1 and 2) incombination with their footnotes (pages 68) and not asstand-alones. For guidance on the use of all the vaccines inthe schedules, including contraindications and precautions touse of a vaccine, providers are referred to the respective ACIPvaccine recommendations.
Printable versions of the regular and catch-up schedules areavailable at http://www.cdc.gov/vaccines/schedulesin variousformats, including landscape and pocket-sized, in regular paperor laminated versions. A parent friendly regular schedule isavailable at http://www.cdc.gov/vaccines/schedules/easy-to-read/child.html#print.
For 2013, several new references and links to additionalinformation have been added, including one for travel vaccinerequirements and recommendations (1). New references alsoare provided for vaccination of persons with primary andsecondary immunodeficiencies. Changes to the previousschedules (2) include the following:
Figure 1, Recommended immunization schedule forpersons aged 0 through 18 years replaces
Recommended immunization schedule for persons aged0 through 6 years and Recommended immunizationschedule for persons aged 7 through 18 years.
Wording was added to bars to represent the respectivevaccine dose numbers in the series.
The meningococcal conjugate vaccine (MCV4) purplebar was extended to age 6 weeks, to reflect licensure ofHib-MenCY vaccine.
The hepatitis A (HepA) vaccine yellow bar was extended tobetter reflect routine age recommendations for use of HepA
vaccine. New green and purple bars were added to reflecthepatitis A vaccine recommendations for older children.
Abbreviations for influenza vaccine were updated withthe anticipation of quadrivalent vaccine for the201314 influenza season.
Pneumococcal polysaccharide vaccine (PPSV23) waadded to Figure 1.
Footnotes were combined and standardized formattingwas used to provide recommendations for each vaccinerelated to routine vaccination, catch-up vaccination, andvaccination of persons with high-risk medical conditionsor under special circumstances.
Meningococcal conjugate vaccine (MCV4) footnoteswere updated to reflect recent recommendations (3). Tetanus and diphtheria toxoids and acellular pertussi(Tdap) vaccine footnotes were updated to reflectrecent recommendations (4).
Influenza vaccine footnotes were updated to provide dosingguidance for children aged 6 months through 8 years forthe 201213 and 201314 influenza seasons (5).
Meningococcal conjugate (MCV4) vaccine minimum agesand intervals were updated in Figure 2, Catch-upimmunization schedule for persons aged 4 months through
18 years who start late or who are more than 1 monthbehindUnited States, 2013, to reflect licensure of Hib-MenCY vaccine.
Advisory Committee on Immunization Practices (ACIP)Recommended Immunization Schedule or Persons Aged 0 Through
18 Years United States, 2013ACIP Childhood/Adolescent Immunization Work Group
Iyabode Akinsanya-Beysolow, MD1
Rene Jenkins, MD2
H. Cody Meissner, MD31Immunization Services Division, National Center for Immunization and Respiratory Diseases, CDC
2Department of Pediatrics and Child Health, Howard University College of Medicine, Washington, D.C.3Tufts Medical Center, Boston, Massachusetts
Corresponding contributor: Iyabode Akinsanya-Beysolow, [email protected], 404-639-5251.
http://www.cdc.gov/vaccines/scheduleshttp://www.cdc.gov/vaccines/schedules/easy-to-read/child.html#printhttp://www.cdc.gov/vaccines/schedules/easy-to-read/child.html#printmailto:[email protected]:[email protected]://www.cdc.gov/vaccines/schedules/easy-to-read/child.html#printhttp://www.cdc.gov/vaccines/schedules/easy-to-read/child.html#printhttp://www.cdc.gov/vaccines/schedules -
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Reerences
1. CDC. Travelers health: vaccinations. Atlanta, GA: US Department ofHealth and Human Services, CDC; 2012. Available at http://wwwnc.cdc.gov/travel/page/vaccinations.htm.
2. CDC. Recommended immunization schedules for persons aged 018yearsUnited States, 2012. MMWR 2012;61(5).
3. CDC, Advisory Committee on Immunization Practices. Resolution no.
10/12-2. Vaccines to prevent meningococcal disease. Atlanta, GA: USDepartment of Health and Human Services, CDC, Advisory Committeeon Immunization Practices; 2012.
4. CDC. Update on use of tetanus toxoid, reduced diphtheria toxoid, andacellular pertussis (Tdap) vaccine in pregnant women. Atlanta, GA: USDepartment of Health and Human Services, CDC.
5. CDC, Advisory Committee on Immunization Practices. Resolution no10/12-3. Vaccines to prevent influenza. Atlanta, GA: US Department oHealth and Human Services, CDC, Advisory Committee onImmunization Practices; 2012. Available at http://www.cdc.gov/vaccinesprograms/vfc/downloads/resolutions/1012-3-flu.pdf.
ACIP Childhood/Adolescent Immunization Work Group
Work Group Chair: Rene Jenkins, MD, Washington, D.C. (ACIP)
Work Group Members: Ruth Karron, MD, Baltimore, Maryland (ACIP); Lorry G. Rubin, MD, New Hyde Park, New York (ACIP); H. Cody Meissner,MD, Boston, Massachusetts; Amy B. Middleman, MD, Houston, Texas; Susan Lett, MD, Boston, Massachusetts; Diane Peterson, Saint Paul, Minnesota;Chris Barry, PA-C, Raleigh, North Carolina; Everett Schlamm, MD, Verona, New Jersey; Katie Brewer, MSN, Silver Springs, Maryland; Patricia Stinchfield,MPH, St Paul, Minnesota; Rosemary Spence, MA, Denver, Colorado; Andrew Kroger, MD, Atlanta, Georgia; William L. Atkinson, MD, Harrisonville,Missouri; Jennifer Hamborsky, MPH, MCHES, Atlanta, Georgia.
Work Group Contributors (CDC): Charles Wolfe, Atlanta, Georgia; Donna Weaver, MN, Atlanta, Georgia; JoEllen Wolicki, Atlanta, Georgia; MelissaBarnett, MS, Atlanta, Georgia; Zunera Mirza, MPH, Atlanta, Georgia
Work Group Secretariat (CDC): Iyabode Akinsanya-Beysolow, MD, Atlanta, Georgia.
http://wwwnc.cdc.gov/travel/page/vaccinations.htmhttp://wwwnc.cdc.gov/travel/page/vaccinations.htmhttp://www.cdc.gov/vaccines/programs/vfc/downloads/resolutions/1012-3-flu.pdfhttp://www.cdc.gov/vaccines/programs/vfc/downloads/resolutions/1012-3-flu.pdfhttp://www.cdc.gov/vaccines/programs/vfc/downloads/resolutions/1012-3-flu.pdfhttp://www.cdc.gov/vaccines/programs/vfc/downloads/resolutions/1012-3-flu.pdfhttp://wwwnc.cdc.gov/travel/page/vaccinations.htmhttp://wwwnc.cdc.gov/travel/page/vaccinations.htm -
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NOTE: The above recommendations must be read along with the ootnotes on pages 68.
FIGURE 1. Recommended immunization schedule or persons aged 0 through 18 years 2013 (or those who all behind or start late, see thecatch-up schedule [Figure 2])
These recommendations must be read with the footnotes that follow. For those who fall behind or start late, provide catch-up vaccination at the earliestopportunity as indicated by the green bars in Figure 1. To determine minimum intervals between doses, see the catch-up schedule (Figure 2). School entry andadolescent vaccine age groups are in bold.
Vaccines Birth1
mo2
mos4
mos6
mos9
mos12
mos15
mos18
mos19-23mos
2-3yrs
4-6yrs
7-10yrs
11-12yrs
13-15yrs
16-18yrs
Hepatitis B1 (HepB)
Rotavirus2 (RV)
RV-1 (2-dose series); RV-5
(3-dose series)
Diphtheria, tetanus, & acellular
pertussis3
(DTaP:
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FIGURE 2. Catch-up immunization schedule or persons aged 4 months through 18 years who start late or who are more than 1 month behind United States, 2013
The figure below provides catch-up schedules and minimum intervals between doses for children whose vaccinations have been delayed. A vaccine series doesnot need to be restarted, regardless of the time that has elapsed between doses. Use the section appropriate for the childs age. Always use this table in conjunc-tion with Figure 1 and the footnotes that follow.
NOTE: The above recommendations must be read along with the ootnotes on pages 68.
Persons aged 4 months through 6 years
Vaccine
Minimum
Age or
Dose 1
Minimum Interval Between Doses
Dose
1 to dose 2
Dose
2 to dose 3
Dose
3 to dose 4
Dose
4 to dose 5
Hepatitis B1 Birth 4 weeks8 weeks
and at least 16 weeks ater frst dose;minimum age or the fnal dose is 24 weeks
Rotavirus2 6 weeks 4 weeks 4 weeks2
Diphtheria, tetanus,pertussis3
6 weeks 4 weeks 4 weeks 6 months 6 months3
Haemophilus infuenzaetype b5
6 weeks
4 weeksi frst dose administered at younger than
age 12 months8 weeks (as fnal dose)
i frst dose administered at age 1214 monthsNo urther doses needed
i frst dose administered at age 15 monthsor older
4 weeks5i current age is younger than 12 months
8 weeks (as fnal dose)5i current age is 12 months or older and frstdose administered at younger than age 12months and second dose administered at
younger than 15 monthsNo urther doses needed
i previous dose administered at age 15 monthsor older
8 weeks (as fnaldose)
This dose onlynecessary or
children aged 12through 59 months
who received3 doses beore age
12 months
Pneumococcal6 6 weeks
4 weeksi frst dose administered at younger than
age 12 months8 weeks (as fnal dose or healthy children)
i frst dose administered at age 12 months orolder or current age 24 through 59 months
No urther doses neededor healthy children i frst dose administered at
age 24 months or older
4 weeksi current age is younger than 12 months
8 weeks (as fnal dose or healthy children)i current age is 12 months or older
No urther doses neededor healthy children i previous dose
administered atage 24 months or older
8 weeks (as fnaldose)
This dose onlynecessary or
children aged 12through 59 months
who received3 doses beore age12 months or orchildren at high
risk who received3 doses at any age
Inactivated poliovirus7 6 weeks 4 weeks 4 weeks6 months7
minimum age 4years or fnal dose
Meningococcal13 6 weeks 8 weeks13 see ootnote 13 see ootnote 13
Measles, mumps, rubella9 12 months 4 weeks
Varicella10 12 months 3 months
Hepatitis A11 12 months 6 months
Persons aged 7 through 18 years
Tetanus, diphtheria; teta-nus, diphtheria, pertussis4
7 years4 4 weeks
4 weeksi irst dose administered at younger than
age 12 months6 months
i frst dose administered at 12 monthsor older
6 monthsi frst dose
administered atyounger than
age 12 months
Human papillomavirus12 9 years Routine dosing intervals are recommended12
Hepatitis A11 12 months 6 months
Hepatitis B
1
Birth 4 weeks
8 weeks
(and at least 16 weeks ater frst dose)
Inactivated poliovirus7 6 weeks 4 weeks 4 weeks7 6 months7
Meningococcal13 6 weeks 8 weeks13
Measles, mumps, rubella9 12 months 4 weeks
Varicella10 12 months
3 monthsi person is younger than age 13 years
4 weeksi person is aged 13 years or older
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1. Hepatitis B (HepB) vaccine. (Minimum age: birth)Routine vaccination:At birthAdministermonovalentHepBvaccineto allnewbornsbeforehospital
discharge.
ForinfantsborntohepatitisBsurfaceantigen(HBsAg)positivemothers,administerHepBvaccineand0.5mLofhepatitisBimmuneglobulin(HBIG)within12hoursofbirth.TheseinfantsshouldbetestedforHBsAgandantibodytoHBsAg(anti-HBs)1to2monthsaftercompletionoftheHepBseries, at age 9 through 18 months (preferably at the next well-child visit).
IfmothersHBsAgstatusisunknown,within12hoursofbirthadministerHepBvaccinetoallinfantsregardlessofbirthweight.Forinfantsweigh-ing
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6b.Pneumococcal polysaccharide vaccine (PPSV23). (Minimum age: 2 years)Vaccination o persons with high-risk conditions: AdministerPPSV23atleast8weeksafterthelastdoseofPCVtochildren
aged 2 years or older with certain underlying medical conditions (seefootnote6c).AsinglerevaccinationwithPPSVshouldbeadministeredafter 5 years to children with anatomic or functional asplenia (includingsicklecelldisease)oranimmunocompromisingcondition.
6c. Medical conditions or which PPSV23 is indicated in children aged 2years and older and or which use o PCV13 is indicated in childrenaged 24 through 71 months: Immunocompetentchildrenwithchronicheartdisease(particularlycya-
notic congenital heart disease and cardiac failure); chronic lung disease(including asthma if treated with high-dose oral corticosteroid therapy),diabetesmellitus;cerebrospinaluidleaks;orcochlearimplant.
Childrenwithanatomicorfunctionalasplenia(includingsicklecelldiseaseand other hemoglobinopathies, congenital or acquired asplenia, or splenicdysfunction);
Childrenwith immunocompromisingconditions:HIV infection,chronicrenal failure and nephrotic syndrome, diseases associated with treatmentwith immunosuppressive drugs or radiation therapy, including malignantneoplasms,leukemias,lymphomasandHodgkindisease;orsolidorgantransplantation,congenitalimmunodeciency.
7. Inactivated poliovirus vaccine (IPV). (Minimum age: 6 weeks)Routine vaccination: AdministeraseriesofIPVatages2,4,618months,withaboosteratage46years.Thenaldoseintheseriesshouldbeadministeredonorafterthe fourth birthday and at least 6 months after the previous dose.
Catch-up vaccination: Intherst6monthsoflife,minimumageandminimumintervalsareonlyrecommendedifthepersonisatriskforimminentexposuretocirculatingpoliovirus(i.e.,traveltoapolio-endemicregionorduringanoutbreak).
If4ormoredosesareadministeredbeforeage4years,anadditionaldoseshould be administered at age 4 through 6 years.
Afourthdoseisnotnecessaryifthethirddosewasadministeredatage4years or older and at least 6 months after the previous dose.
IfbothOPVandIPVwereadministeredaspartofaseries,atotalof4dosesshould be administered, regardless of the childs current age.
IPVisnotroutinelyrecommendedforU.S.residentsaged18yearsorolder. Forothercatch-upissues,seeFigure2.
8. Inuenza vaccines. (Minimum age: 6 months or inactivated inuenzavaccine [IIV]; 2 years or live, attenuated inuenza vaccine [LAIV])Routine vaccination: Administerinuenzavaccineannuallytoall childrenbeginningatage6
months. For most healthy, nonpregnant persons aged 2 through 49 years,eitherLAIVorIIVmaybeused.However,LAIVshouldNOTbeadministeredto some persons, including 1) those with asthma, 2) children 2 through 4yearswhohadwheezinginthepast12months,or3)thosewhohaveanyotherunderlyingmedicalconditionsthatpredisposethemtoinuenzacomplications.ForallothercontraindicationstouseofLAIVseeMMWR2010;59 (No. RR-8), available athttp://www.cdc.gov/mmwr/pdf/rr/rr5908.pdf.
Administer1dosetopersonsaged9yearsandolder.For children aged 6 months through 8 years: Forthe201213season,administer2doses(separatedbyatleast4weeks)tochildrenwhoarereceivinginuenzavaccineforthersttime.Foradditionalguidance,followdosingguidelinesinthe2012ACIPinuenzavaccinerecommendations,MMWR2012;61:613618,availableat http://www.cdc.gov/mmwr/pdf/wk/mm6132.pdf.
Forthe201314season,followdosingguidelinesinthe2013ACIPinuenzavaccine recommendations.
9. Measles, mumps, and rubella (MMR) vaccine. (Minimum age: 12 monthsor routine vaccination)Routine vaccination: AdministertherstdoseofMMRvaccineatage12through15months,
and the second dose at age 4 through 6 years. The second dose may beadministeredbeforeage4years,providedatleast4weekshaveelapsedsincetherstdose.
Administer1doseofMMRvaccinetoinfantsaged6through11monthsbefore departure from the United States for international travel. Thesechildrenshouldberevaccinatedwith2dosesofMMRvaccine,therstat age 12 through 15 months (12 months if the child remains in an areawherediseaseriskishigh),andtheseconddoseatleast4weekslater.
Administer2dosesofMMRvaccinetochildrenaged12monthsandolderbeforedeparturefromtheUnitedStatesforinternationaltravel.Thersdose should be administered on or after age 12 months and the seconddoseatleast4weekslater.
Catch-up vaccination: Ensurethatall school-agedchildrenandadolescentshavehad2dosesoMMRvaccine;theminimumintervalbetweenthe2dosesis4weeks.
10. Varicella (VAR) vaccine. (Minimum age: 12 months)Routine vaccination: AdministertherstdoseofVARvaccineatage12through15months
and the second dose at age 4 through 6 years. The second dose may beadministered before age 4 years, provided at least 3 months have elapsedsincetherstdose.Iftheseconddosewasadministeredatleast4weekaftertherstdose,itcanbeacceptedasvalid.
Catch-up vaccination: Ensurethatallpersonsaged 7through18 yearswithoutevidenceo
immunity (see MMWR 2007;56 [No. RR-4], available athttp://www.cdc.gov/mmwr/pdf/rr/rr5604.pdf) have 2 doses of varicella vaccine. For childrenaged 7 through 12 years the recommended minimum interval betweendosesis3months(iftheseconddosewasadministeredatleast4weekaftertherstdose,itcanbeacceptedasvalid);forpersonsaged13yearsandolder,theminimumintervalbetweendosesis4weeks.
11. Hepatitis A vaccine (HepA). (Minimum age: 12 months)Routine vaccination: Initiatethe2-doseHepAvaccineseriesforchildrenaged12 through23
months; separate the 2 doses by 6 to 18 months. Childrenwhohavereceived1doseofHepAvaccinebeforeage24monthsshouldreceiveaseconddose6to18monthsaftertherstdose.
Foranypersonaged2yearsandolderwhohasnotalreadyreceivedtheHepAvaccineseries,2dosesofHepAvaccineseparatedby6to18monthsmaybe administered if immunity against hepatitis A virus infection is desired.
Catch-up vaccination: Theminimumintervalbetweenthetwodosesis6months.Special populations: Administer2dosesofHepAvaccineatleast6monthsaparttopreviously
unvaccinated persons who live in areas where vaccination programs targeolderchildren,orwhoareatincreasedriskforinfection.
12. Human papillomavirus (HPV) vaccines. (HPV4 [Gardasil] and HPV2[Cervarix]). (Minimum age: 9 years)Routine vaccination: Administera3-doseseriesofHPVvaccineonascheduleof0,1-2,and6monthstoalladolescentsaged11-12years.EitherHPV4orHPV2maybeusedforfemales,andonlyHPV4maybeusedformales.
Thevaccineseriescanbestartedbeginningatage9years. Administertheseconddose1to2monthsafterthefrst dose and the third
dose 6 months after the frst dose(atleast24weeksaftertherstdose)Catch-up vaccination: Administerthevaccineseriestofemales(eitherHPV2orHPV4)andmales(HPV4)atage13through18yearsifnotpreviouslyvaccinated.
Userecommendedroutinedosingintervals(seeabove)forvaccineseriescatch-up.
13. Meningococcal conjugate vaccines (MCV). (Minimum age: 6 weeksor Hib-MenCY, 9 months or Menactra [MCV4-D], 2 years or Menveo[MCV4-CRM]).Routine vaccination: AdministerMCV4vaccineatage1112years,withaboosterdoseatage
16 years. Adolescentsaged11 through18 yearswith humanimmunodeciencyvirus(HIV)infectionshouldreceivea2-doseprimaryseriesofMCV4,withatleast8weeksbetweendoses.SeeMMWR2011;60:10181019availableat:http://www.cdc.gov/mmwr/pdf/wk/mm6030.pdf.
Forchildrenaged9monthsthrough10 yearswithhigh-riskconditionssee below.
Catch-up vaccination: AdministerMCV4vaccineatage13through18yearsif notpreviously
vaccinated. Iftherstdoseisadministeredatage13through15years,aboosterdose
should be administered at age 16 through 18 years with a minimum intervaofatleast8weeksbetweendoses.
Iftherstdoseisadministeredatage16yearsorolder,aboosterdoseinot needed.
Forothercatch-upissues,seeFigure2.
http://www.cdc.gov/mmwr/pdf/rr/rr5908.pdfhttp://www.cdc.gov/mmwr/pdf/rr/rr5908.pdfhttp://www.cdc.gov/mmwr/pdf/wk/mm6132.pdfhttp://www.cdc.gov/mmwr/pdf/wk/mm6132.pdfhttp://www.cdc.gov/mmwr/pdf/rr/rr5604.pdfhttp://www.cdc.gov/mmwr/pdf/rr/rr5604.pdfhttp://www.cdc.gov/mmwr/pdf/rr/rr5604.pdfhttp://www.cdc.gov/mmwr/pdf/wk/mm6030.pdfhttp://www.cdc.gov/mmwr/pdf/wk/mm6030.pdfhttp://www.cdc.gov/mmwr/pdf/rr/rr5604.pdfhttp://www.cdc.gov/mmwr/pdf/rr/rr5604.pdfhttp://www.cdc.gov/mmwr/pdf/wk/mm6132.pdfhttp://www.cdc.gov/mmwr/pdf/wk/mm6132.pdfhttp://www.cdc.gov/mmwr/pdf/rr/rr5908.pdf -
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Vaccination o persons with high-risk conditions: Forchildrenyoungerthan19monthsofagewithanatomicorfunctionalasplenia(includingsicklecelldisease),administeraninfantseriesofHib-MenCYat2,4,6,and12-15months.
Forchildrenaged2through18monthswith persistentcomplementcomponentdeciency,administereitheraninfantseriesofHib-MenCYat2,4,6,and12through15monthsora2-doseprimaryseriesofMCV4-Dstartingat9months,withatleast8weeksbetweendoses.Forchildrenaged 19 through 23 months with persistent complement componentdeciencywhohavenotreceivedacompleteseriesofHib-MenCYorMCV4-D,administer2primarydosesofMCV4-Datleast8weeksapart.
Forchildrenaged 24monthsand olderwith persistentcomplementcomponentdeciencyoranatomicorfunctionalasplenia(includingsicklecelldisease),whohavenotreceivedacompleteseriesofHib-MenCYorMCV4-D,administer2primarydosesofeitherMCV4-DorMCV4-CRM.If
MCV4-D(Menactra)isadministeredtoachildwithasplenia(includingsicklecelldisease),donotadministerMCV4-Duntil2yearsofageandatleast4weeksafterthecompletionofallPCV13doses.SeeMMWR2011;60:13912available athttp://www.cdc.gov/mmwr/pdf/wk/mm6040.pdf.
Forchildrenaged9monthsandolderwhoareresidentsofortravelerstocountriesintheAfricanmeningitisbeltortotheHajj,administeranageappropriateformulationandseriesofMCV4forprotectionagainstserogroupsAandW-135.PriorreceiptofHib-MenCYisnotsucientforchildrentravelingtothemeningitisbeltortheHajj.SeeMMWR2011;60:13912available athttp://www.cdc.gov/mmwr/pdf/wk/mm6040.pdf.
Forchildrenwhoarepresentduringoutbreakscausedbyavaccineserogroup, administer or complete an age and formulation-appropriate serieofHib-MenCYorMCV4.
Forboosterdosesamongpersonswithhigh-riskconditionsrefertohttp:/www.cdc.gov/vaccines/pubs/acip-list.htm#mening.
Additional Vaccine Inormation
Forcontraindicationsandprecautionstouseofavaccineandforadditionalinformation regarding that vaccine, vaccination providers should consulttherelevantACIPstatementavailableonlineat http://www.cdc.gov/vaccines/pubs/acip-list.htm.
Forthepurposesofcalculatingintervalsbetweendoses,4weeks=28days.Intervalsof4monthsorgreateraredeterminedbycalendarmonths.
Informationon travelvaccinerequirementsand recommendationsisavailable athttp://wwwnc.cdc.gov/travel/page/vaccinations.htm.
Forvaccinationofpersonswithprimaryandsecondaryimmunodecienciessee Table 13, Vaccination of persons with primary and secondaryimmunodeciencies,inGeneral Recommendationson Immunization(ACIP),availableathttp://www.cdc.gov/mmwr/preview/mmwrhtmlrr6002a1.htm;andAmericanAcademyofPediatrics.PassiveimmunizationIn:PickeringLK,BakerCJ,KimberlinDW,LongSSeds.Redbook:201reportoftheCommitteeonInfectiousDiseases.29thed.ElkGroveVillageIL:AmericanAcademyofPediatrics.
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