7/29/2019 Group B Streptococci or S. agalactiae

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Group B Streptococci (GBS)(S. agalactiae)

Dr.Aravind

7/29/2019 Group B Streptococci or S. agalactiae

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Group B Babies (meningitis and Pneumonia)

Facultative anaerobe

Catalase negative

Group specific carbohydrate antigen (B)

hemolytic

Hippurate +

CAMP +

Bacitracin Resistant

Capsulated Polysaccharide (III **)

Dr.Aravind

7/29/2019 Group B Streptococci or S. agalactiae

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Dr.Aravind

7/29/2019 Group B Streptococci or S. agalactiae

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Epidemiology:

URT and genitourinary tract

New born infection - birth canal, premature merupture, prolonged labor, preterm birth.

Women Postpartum sepsis risk

Men and women UTI.

Group III is capsular antigen predominant one meningitis

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Pathogenesis:

Virulence is associated with a polysaccharide cand hydrolytic enzymes (Hemolysins) for tissu

Clinical Conditions:Neonatal Meningitis

Neonatal Pneumonia

Septicemia

Postpartum sepsis

UTI

Endometritis

Dr.Aravind

7/29/2019 Group B Streptococci or S. agalactiae

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Meningit

Fever, Po

feeding,

irritability

BulgingFontanilla

seizers.

PneumoFever, C

pleural e

consolid

ray infilt

Septicemia

Clinical Features

Adults:

Postpartum sepsis

UTI

Endometritis

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Diagnosis:

Specimens CSF or Blood

CAMP + Hippurate +

Bacitracin resistance

Capsular antigen

Treatment:

Penicillin G

Vancomycin Penicillin sensitive pts

Dr.Aravind