Global Manufacturing & Supply · Any questions? Do more, feel better, live longer . ... Horlicks,...
Transcript of Global Manufacturing & Supply · Any questions? Do more, feel better, live longer . ... Horlicks,...
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Global Manufacturing & Supply
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Our agenda today
1. About GlaxoSmithKline, Global Manufacturing and Supply (GMS) and
biopharmaceutical production within GMS
2. Future Leader Program in Global Manufacturing and Supply
3. Should I apply?
4. How do I apply?
5. Any questions?
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Do more, feel better, live longer
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We are a science-led global healthcare company, making a range of products that help people do more, feel better and live longer. Our commercial success depends on creating innovative new products and making these accessible to as many people who need them as possible.
Pharmaceuticals Vaccines Consumer Healthcare
Respiratory disease, cancer,
heart disease, epilepsy, HIV ,
lupus, and skin conditions like
psoriasis.
Influenza, rotavirus, cervical
cancer, measles, mumps, rubella,
hepatitis, polio, tetanus and
meningitis.
Wellness, Skin Health, Oral
Health and Nutrition.
Our portfolio includes well-known
brands such as: Horlicks, Panadol
and Sensodyne.
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Manufacture the products that enable people to do more, feel better and live longer
Ensure the delivery of quality and value to the patient at the end of the Supply Chain
In Global Manufacturing and Supply we:
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Types of Pharmaceutical Compounds
• Small Molecules
– “Traditional” pharmaceutical compounds
– Chemically produced, defined
Types of Biopharmaceuticals:
• Vaccines
• Therapeutic Proteins
– Monoclonal antibodies (MAb)
– MAb-derivatives (e.g. domain antibodies)
– Conjugated peptides
CDC Public Health
Information Library
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Biopharmaceuticals within GSK
• Biopharm products are now over 20% of GSK’s pipeline
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GSK is committed to the development of biopharmaceutical products
Compound Types Indication
2862277 tumour necrosis factor receptor-1 (TNFR1) domain
antibody acute lung injury
sirukumab IL6 human monoclonal antibody rheumatoid arthritis
2398852 SAP monoclonal antibody cancer
3052230 fibroblast growth factor ligand trap cancer
249320 myelin-associated glycoprotein monoclonal antibody stroke
2586881 recombinant human angiotensin converting enzyme 2 acute lung injury
933776 beta amyloid monoclonal antibody geographic retinal atrophy
3196165 granulocyte macrophage colony stimulating factor
monoclonal antibody rheumatoid arthritis
ozanezumab neurite outgrowth inhibitor (NOGO-A) monoclonal
antibody amyotrophic lateral sclerosis
Arzerra (ofatumumab) CD20 human monoclonal antibody
chronic lymphocytic leukaemia, first line therapy &
use in relapsed patients; diffuse large B cell
lymphoma (relapsed patients); follicular lymphoma
(refractory & relapsed patients); multiple sclerosis
Benlysta (belimumab) B lymphocyte stimulator monoclonal antibody
systemic lupus erythematosus; vasculitis;
ideopathic memembranous nephropathy;
myasthenia gravis
mepolizumab IL5 monoclonal antibody severe asthma; nasal polyposis
Tanzeum (albiglutide) GLP 1 agonist type 2 diabetes
raxibacumab protective antigen inhibitor inhalation anthrax
2618960 IL7 receptor monoclonal antibody autoimmune disease
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GSK Biopharmaceutical Production
• GSK’s fully integrated Biopharmaceutical Supply Chain
– Primary Production in Upper Merion PA and Rockville MD
• Biosynthesis (cell culture or fermentation) and purification
– Secondary Production in Barnard Castle UK and Parma Italy
• Final formulation and aseptic filling
Upper Merion
Rockville
Parma Barnard Castle
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Located in King of Prussia, a suburb of Philadelphia, PA.
100,000 ft2 of production space and 240,000ft2 total footprint.
Staffed by approximately 240 people, 24/7 operation.
Site constructed in 1997. Cell Culture Value Stream added in 2005. Full retrofit creating Microbial Value Stream in 2010
Biopharmaceutical Primary Production
Upper Merion
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Located in the suburbs of Baltimore, MD and Washington, DC.
Large Scale Manufacturing (LSM): 80,000 ft2 of production space and 290,000ft2 total footprint.
Small Scale Manufacturing (SSM): 130,000 ft2 total footprint.
Biopharmaceutical Primary Production
Rockville
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Biopharmaceutical Secondary Production Barnard Castle UK and Parma Italy
Liquids & Freeze Dry Products Clinical and commercial capacity
Recognized world-class sites in quality, technology, and controls
Multiple formats (vials, syringes) and dose ranges (0.5 mL – 100 mL)
Large lyophilization and overall capacity
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The Future Leader Programme in Global Manufacturing & Supply
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On the job development
through challenging roles
Formal training programmes and
structured assessment
Multiple rotations across/within
functions ensure early breadth of
technical experience
Senior leadership, mentoring/ buddy,
coaching and support
Future Leaders Programme characteristics
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Program Objectives
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Attract and retain the best technical graduates
Accelerate development of top technical talent for key manufacturing and supply areas
Provide a robust technical career foundation, with the ability to spot emerging leadership and adapt the development accordingly.
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Global Manufacturing and Supply
Future Leaders Programme
• This is a unique opportunity to gain a broad range of experience in
biopharmaceutical production and learn from experts
• 3 Rotations in different sites or parts of our business (with the potential for
international assignment)
• 3 Year Development Program
• Target of 50 recruits per year, globally
• Development Framework:
– Technical Expertise
– Business Execution
– Leadership Expectations
– Personal Skills
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Program Structure
Start Date 16 months 18 months 8 months
360
Manager
Expectation
Setting
Energy4Performance
Harvard
ManageMentor
Practical Coaching in
the Workplace
ADP
Coaching and/or Mentoring and Buddying
Review
Point
70
20
10
Development
Web Pages
1
Rotation
2
Rotation
3
Rotation Rotation
Regular 1-to-1s, feedback and Performance and Development Plan conversations
GSK Global curriculum, tools and resources to be included as appropriate:
Review
Point
Tra
nsitio
n to
Bu
sin
ess, p
en
din
g p
erfo
rma
nce
and
busin
ess n
ee
ds
Alu
mn
i pro
gre
ssio
n tra
cke
d &
deve
lope
d
Graduate
Community
Intranet
Specific Technical Training
Fundamentals of
Leadership
First Line Leader
Management
Essentials
Interpersonal Skills
Module Personal Skills Module Joining GSK
12 months
September
January
January
August
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What Might I Do or Learn during Rotations?
Engineering and Science are the Core of Our Business
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• Technology transfer
• Participate/Lead production deviation investigations
• Analyze manufacturing data
• Implementation of new manufacturing technology
• Process improvement projects
• Process development
• Process validation
• Technical writing
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What Type of Work Would I Do After the Rotations?
Engineering and Science are the Core of Our Business
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• Product Owners
– Responsible for technical governance of our
products and maintenance of the product control
strategy
• Process Engineers & Platform Experts
– Experts in the interaction between process
equipment and the product
• Technologists
– Scientific graduates who are responsible for
executing key technical activities including trials,
improvement projects, root cause analysis,
validation, report writing etc.
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Development on the placement 7
0%
On the job d
evelo
pm
ent • Delivery of
projects
• Ad hoc support of additional projects for the host team
• Development of technical skills through doing
• Development of and awareness of High Performance Behaviours
• Completion of Performance and Development Planto track development
20%
Learn
fro
m o
thers
• Shadowing opportunities
• Mentors
• Buddy system
• Peers
• Networking
• Induction opportunities to areas outside the host team of the participant
10
% F
orm
al develo
pm
ent • Specific Technical
or Supply Chain Training
• Harvard Manage Mentor
• Site visits (where appropriate)
• GSK Experience
• Fundamentals of Leadership
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20 00 Month 0000 Presentation title in footer
Meet Our Graduates!
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Alicia’s Video
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Engineering at GSK
00 Month 0000 Presentation title in footer
Watch Alicia’s video!
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Should I apply?
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What do you need to apply?
23 00 Month 0000 Presentation title in footer
• Do you have an engineering or science degree with strong credentials
(i.e., GPA >3.5; preference for MS or PhD candidates)?
• Applicants must hold a full US work permit for this program
• Do you have strengths in communication, influencing, teamwork and
problem-solving?
• Do you want to help people to do more, feel better and live longer?
• Do you demonstrate GSK’s values?
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How do I apply?
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The Application Process
• Online application form
– Do you have the right degree background?
– Why do you want to work at GSK?
• Phone Interview
• Assessment Centre
- Technical Assessment
- Competency Assessment
- Group Assessment
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What does it involve?
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Applications open
Sep 2014
Virtual / Telephone Interviews
Technical and behavioural assessment
Assessment Centre
Technical and behavioural assessment
Nov 2014
Offer
We look to offer within 2 weeks
Join GSK
Dec 2014 or
Sep 2015
Apply online http://gskbigquestions.com/
For additional information http://us.gsk.com/en-us/careers/undergraduates/future-
leaders-us-technical-development/
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Join the conversation
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Any questions?
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