Get the most from your NGS...Discover new and innovative solutions, dedicated for use with any NGS...

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Transcript of Get the most from your NGS...Discover new and innovative solutions, dedicated for use with any NGS...

Page 1: Get the most from your NGS...Discover new and innovative solutions, dedicated for use with any NGS workflow Streamline your next-generation sequencing (NGS) workflow and achieve high-quality
Page 2: Get the most from your NGS...Discover new and innovative solutions, dedicated for use with any NGS workflow Streamline your next-generation sequencing (NGS) workflow and achieve high-quality

Sample & Assay Technologies

Get the most from your NGS

NGS1113S1W

W

Better results — on any sequencing platform

Discover new and innovative solutions,

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Streamline your next-generation sequencing (NGS) workflow and achievehigh-quality results you can rely on.

■ Highly specific and selective nucleic acid purification and target enrichment

■ Unbiased whole genome amplification from a single cell

■ High DNA library yields using optimized workflows that allow ~50% time-savings

■ Outstanding results on any sequencing platform

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Visit www.qiagen.com/goto/NGS to learn more!

Page 3: Get the most from your NGS...Discover new and innovative solutions, dedicated for use with any NGS workflow Streamline your next-generation sequencing (NGS) workflow and achieve high-quality

New Products, Services, and Solutions

SCIENCE

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Page 4: Get the most from your NGS...Discover new and innovative solutions, dedicated for use with any NGS workflow Streamline your next-generation sequencing (NGS) workflow and achieve high-quality

The Leading Journal for Cell Signaling

CANCER BIOLOGY

Vemurafenib Potently Induces EndoplasmicReticulumStress–Mediated Apoptosis inBRAFV600EMelanoma CellsD. Beck et al. (F. Meier), Sci. Signal. 6, ra7 (2013)

NEUROSCIENCE

Requirement for Nuclear CalciumSignaling inDrosophila Long-TermMemoryJ.-M. Weislogel et al. (H. Bading), Sci. Signal. 6, ra33 (2013)

CELL AND MOLECULAR BIOLOGY

ANontranscriptional Role for HIF-1α as a DirectInhibitor of DNAReplicationM. E. Hubbi et al. (G. L. Semenza), Sci. Signal. 6, ra10 (2013)

IMMUNOLOGY

Monovalent andMultivalent Ligation of theB Cell Receptor Exhibit Differential Dependenceupon Syk and Src Family KinasesS. Mukherjee et al. (A. Weiss), Sci. Signal. 6, ra1 (2013)

COMPUTATIONAL AND SYSTEMS BIOLOGY

Cross-Species Protein InteractomeMappingReveals Species-SpecificWiring of StressResponse PathwaysJ. Das et al. (H. Yu), Sci. Signal. 6, ra38 (2013)

Join the ranks of high-profile paperspublished in Science Signaling:

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Editor

Nancy R. Gough, Ph.D.

AAAS, Washington, DC

Submit your researchScienceSignaling.org

Recommend to your libraryScienceOnline.org/recommend

Page 5: Get the most from your NGS...Discover new and innovative solutions, dedicated for use with any NGS workflow Streamline your next-generation sequencing (NGS) workflow and achieve high-quality

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Page 6: Get the most from your NGS...Discover new and innovative solutions, dedicated for use with any NGS workflow Streamline your next-generation sequencing (NGS) workflow and achieve high-quality

Electronically submit your new product description or product literature information! Go to www.sciencemag.org/products/newproducts.dtl for more information.

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Newly offered instrumentation, apparatus, and laboratory materials of interest to researchers in all disciplines in academic, industrial, and governmental organizations are

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Page 7: Get the most from your NGS...Discover new and innovative solutions, dedicated for use with any NGS workflow Streamline your next-generation sequencing (NGS) workflow and achieve high-quality

Integrating Science, Engineering, and Medicine

NEUROLOGY

ATheoretically Based Index of ConsciousnessIndependent of Sensory Processing and BehaviorA. G. Casali et al. (M. Massimini), Sci. Transl. Med. 5 198ra105 (2013)

IMMUNOLOGY

TGFβReceptorMutations Impose a StrongPredisposition for Human Allergic DiseaseP.A. Frischmeyer-Guerrerio et al. (H. Dietz), Sci. Transl. Med. 5 195ra94(2013)

BIOENGINEERING

AHumanDiseaseModel of Drug Toxicity-InducedPulmonary Edema in a Lung-on-a-ChipMicrodeviceD. Huh et al. (D. Ingber), Sci. Transl. Med. 5 159ra147 (2012)

CANCER

Genome-WideMutational Signatures of AristolochicAcid and its Application as a Screening ToolS.L. Poon et al. (B. T. Teh), Sci. Transl. Med. 5 197ra101 (2013)

TISSUE ENGINEERING

Human Cartilage Repair with a PhotoreactiveAdhesive-Hydrogel CompositeB. Sharma et al. (J.J. Elisseeff ), Sci. Transl. Med. 5 167 ra6 (2013)

Join the ranks of high-profile paperspublished in Science Translational Medicine:

Publishing results that harness thebasic sciences to advance humanhealth in all areas of medicine

[email protected]

Chief Scientif ic Advisors

Elazer Edelman, M.D., Ph.D.Massachusetts Institute of Technology

Garret FitzGerald, M.D.University of Pennsylvania

Editor

Katrina L. Kelner, Ph.D.

AAAS, Washington, DC

Submit your researchScienceTranslationalMedicine.org

Recommend to your libraryScienceOnline.org/recommend

Page 8: Get the most from your NGS...Discover new and innovative solutions, dedicated for use with any NGS workflow Streamline your next-generation sequencing (NGS) workflow and achieve high-quality

Make ends meet.

Gibson Assembly® Cloning KitNew England Biolabs has revolutionized your laboratory’s

standard cloning methodology. The Gibson Assembly

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Save time, without sacrificing efficiency.

Making ends meet is now quicker and easier than ever before,

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In-Fusion®Gibson Assembly

GeneArt®

1 kb 3kb 5 kb

Numberofrecombinantcolonies

(x103)

Fragment size

Assembly reactions containing 25 ng of linear pUC19 vector and 0.04 pmolof each fragment were performed following individual suppliers’ recommendedprotocols and using the competent cells provided with the kit. The total numberof recombinant colonies was calculated per 25 ng of linear pUC19 vector addedto the assembly reaction.

Gibson Assembly Cloning Kit provides robust

transformation efficiencies