Extraction Met h on Green Chemistry
Transcript of Extraction Met h on Green Chemistry
![Page 1: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/1.jpg)
Fulgentius N. L
Pennsylvania State
(717) 77
ful4@p
24 Jun
Extraction Methon Green C
______________ugemwa, Ph.D.
e University –York
71-8409
psu.edu
e 2009
hods that FocusChemistry______________
![Page 2: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/2.jpg)
Acknowle
Eric J. LUndergraduate Studen
edgment
Lawrencent at Penn State, York
![Page 3: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/3.jpg)
Summ
• A brief overview of ex• Evidence that extrac
and/or ethyl alcohol w• Where do we go from
mary
xtraction methodsctions using water work
m here?
![Page 4: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/4.jpg)
Extraction Using G
Useful methods inclu• Steam distillation, hydr• Vacuum & atmospheric• Supercritical fluids
Carbon dioxide
Green Chemistry
de rodistillationc sublimation
![Page 5: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/5.jpg)
Other Extract
Some of the organic extract natural products
• Acetone, benzene, 1-bdichloromethane, ethanacetate, hexanes, methxylene.
tion Methods
solvents used to s utanol, chloroform, nol, ether, ethyl hanol, toluene &
![Page 6: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/6.jpg)
Green extractioon by the barrel
![Page 7: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/7.jpg)
Soxhlet eextractor
![Page 8: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/8.jpg)
We use ethyl alcacetone
to extract trimyris
cohol instead of or ether tin from nutmeg
![Page 9: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/9.jpg)
Betulin from White Birch
![Page 10: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/10.jpg)
Betuulin
![Page 11: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/11.jpg)
Carnosic acid frrom Rosemary
![Page 12: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/12.jpg)
Carnossic acid
![Page 13: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/13.jpg)
Betulin e
Solvent system (200 mL) T
45% EtOH/45% EtAc/10% water 4
50% EtOH/50% EtAc 4
EtOH 2
EtAc 2
extracts
Total extract (g) from 20g after 96 hours at room temperature
4.0 ± 0.4
4.4 ± 0.5
2.2 ± 0.2
2.5 ± 0.3
![Page 14: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/14.jpg)
Pure BSolvent system
45% EtOH/45% EtAc/10% water
50% EtOH/50% EtAc
Hot toluene
Betulin Betulin, g /4 g
2.8 ± 0.4
3.0 ± 0.5
3.2 ± 0.6
![Page 15: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/15.jpg)
Carnos
Solvent system A
45% EtOH/45% EtAc/10% water 4
SC-CO2
Acetone 2
Methanol
Butanone 2
ic acid
Amount of carnosic acid- 96 hours, mg/g ± SD 40.5 ± 1.5
35.7 ± 1.6
26.2 ± 1.5
15.9 ± 1.3 13.2 ± 1.5
20.5 ± 1.2
![Page 16: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/16.jpg)
ApplicNatural products arNutraceuticalsCosmeceuticalsPharmaceuticalsInsecticidesInsect repellants
cationsre used as
![Page 17: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/17.jpg)
Application of G
D. Adairs Cosmeticssolventshttp://dadairs.comMoisturizing Ginseng GChamomile MoisturizingOther products contain geranium, white oak bawitch hazel, sage, whitegrass and jasmine.
reen Chemistry
, Inc. uses green
Gelg Cleanserextracts from
rk, horsetail, comfrey, e pine, fennel, lemon
![Page 18: Extraction Met h on Green Chemistry](https://reader031.fdocuments.in/reader031/viewer/2022012915/61c61570e8ac6d303b21f8ef/html5/thumbnails/18.jpg)
Take-home
The extraction of manatural sources can green solvents. Experiment with watbefore using other s
e message
ny compounds from be carried out using
ter or ethyl alcohol solvents.