flow chemistry systems - Dolomite Microfluidics · What are the Dolomite Flow Chemistry Systems?...

Innovators in microfluidic solutions

flow chemistry systemseasy-to-use, affordable andmodular

What are the Dolomite Flow Chemistry Systems?

» Continuous Liquid Extraction: the Dolomite Membrane chip enables continuous work-up.

» Sample Injection Valves: allows for small amounts of material to be injected into the flow chemistry system. Ideal for reaction optimization and limited material.

» Pressurized Input: pressurize solvent/reagent bottles to minimize input cavitation and gas bubble formation. Ideal for viscous or low boiling point liquids.

Upgrade your system to increase its capability:

The Dolomite Flow Chemistry Systems are easy-to-use, affordable modular systems for a range of flow chemistry applications. The systems allow multiple configurations for lab scale reactions and are upgradable for more functionality. The systems offer a wide range of reaction parameters with flow rates from <1.0µL/min to >10mL/min and temperatures from 1°C to 250°C.

» System 1 (A&B): For beginners and educational needs.

» System 2 (A&B): For continuous reactions on a larger scale.

» System 3 (A&B): For the widest range of chemistry - optimization, scale-up and multi-step reactions all in one.

System A allows only PC control of pump. System B also allows manual control of pumps via the front panel.

3 entry level standard systems:

A list of Dolomite Flow Chemistry System parts:

Standard Optional

System

Standard System Parts 1A 1B 2A 2B 3A 3B

Mitos Duo XS Basic Pump 2 2

Mitos Duo XS Pump 2 2

Meros TCU-125 (1 to 125°C)

Hotplate (RT to 250°C)

Tubing Starter Pack

Reagent/Solvent Bottles

Back Pressure Regulator

FCC Software

Reactor Options

250µl Microreactor

Micromixer Chip

T-Junction Chip

Long Channel Chip

4ml Tube Reactor PTFE or SS

16ml Tube Reactor PTFE or SS

System Upgrades

Additional Pump Module

FCC Advanced Software

Sample Injection (2 Valves)

In-line Liquid Separation

Pressurized Input

Laptop

North America Officet: 617 848 1211e: [email protected]

UK Head Office (Europe, S.E. Asia, Australasia, China, Middle East, Africa)t: +44 (0)1763 242 491e: [email protected]: www.dolomite-microfluidics.com

Japan Office (Japan, Korea and Taiwan)t: 045 263 8211e: [email protected]

India Officet: +91 22 2686 4410e: [email protected]

Brasil Office (Latin America)t: +55 11 5083 4963e: [email protected]

Dolomite Flow Chemistry System Benefits:

• Wide range of reactor types: chips in glass, tubes in PTFE or Stainless Steel from 2.5µL to 16ml.

• High performance pumps: smooth, chemically resistant syringe pumps can act as single shot or work together to operate continuously up to 6 bar.

• Temperature control options: choose from the TCU-125 for chips (1°C to 125°C) or Hotplate for Tube Reactors (RT to 250°C).

• Rapid reaction configuration: allows for optimization on a small scale, and direct scaling up of reactions in a safe and reproducible manner.

• Intuitive reaction automation: Flow Control Centre Advanced PC Software allows accurate and reproducible reaction automation with easy control of heating, pumping and key experiment parameters.

Why Flow Chemistry?

• Safer, cleaner chemistry via greater control of reaction temperature, stoichiometry, mixing and time.

• Access to increased chemical space. Reactions can be performed that cannot be carried out under batch conditions.

» Reactions generating unstable intermediates.

» Increased reaction rates by super-heating of reactions.

» Increased control of potentially hazardous reactions including exothermic and gas evolving reactions or reactions with dissolved gases.

flow chemistry systems - Dolomite Microfluidics · What are the Dolomite Flow Chemistry Systems?...

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