Frimley CCG Prescribing Newsletter Volume 12 Issue 4 June ...
Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS...
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![Page 1: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/1.jpg)
Evidence-based Practice
Dr Christine MarshallDr Richard de FerrarsDr Andrew Cochrane
Frimley VTS September 2014
![Page 2: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/2.jpg)
What on Earth Should We Try to Cover?
The right treatment for every disease that you will ever come across?
Everything you ever needed to know about statistics?
Every important paper ever published?
![Page 3: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/3.jpg)
What on Earth Should We Try to Cover?
Why all the fuss granddad?- EBM is so yesterday….
The big issues: - quality, risk, wrong answers
Can you make it work?- CSA and real life
![Page 4: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/4.jpg)
What is Evidence-Based Medicine?
The art of stating
the bleeding
obvious?
![Page 5: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/5.jpg)
There are lies..
Damned lies....
And statistics......Mark Twain
Mysterious magic
& beyond
comprehension?
What is Evidence-Based Medicine?
![Page 6: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/6.jpg)
“The conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients.”
Centre for Evidence-based Medicine
“Evidence based medicine is the integration of best research evidence with clinical expertise and patient values.”
David Sackett
What is Evidence-Based Medicine?
![Page 7: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/7.jpg)
Barriers & Limitations in Primary Care
Let’s set off positively.....
What problems do you see with using EBM in your everyday work?
Time to debate…
![Page 8: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/8.jpg)
EBM has had its day in Primary Care.
We should be glad to show it the door
1.Vote
2.Proponents 5 mins Then Q&A
3.Opponents 5 mins Then Q&A
4.Proponents 2 mins to close
5.Opponents 2 mins to close
6.Vote
Time to Debate
![Page 9: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/9.jpg)
Spot the Flaws…
Patients rarely have one-dimensional problems Evidence is limited with older people, chronic
conditions, complex multiple co-morbidities GPs may use diagnosis by prognosis (watchful waiting)
or therapeutic response rather than pure hypothetical-deductive model
Objective measurable science vs. mysterious art of medicine
“Doctors shaping the square peg of the evidence to fit the round hole of the patient's life.” A Freeman BMJ 2001 323:1
Can it fit into a normal consultation?
![Page 10: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/10.jpg)
What on Earth Should We Try to Cover?
Why all the fuss granddad?- EBM is so yesterday….
The big issues: - quality, risk, wrong answers
Can you make it work?- CSA and real life
![Page 11: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/11.jpg)
Quality of data
Quality of sources of data
Let’s talk high quality…
![Page 12: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/12.jpg)
Quality Data?
1. My GPR (who has just passed his MRCGP) says thiazides are good anti-hypertensives
2. The NICE guidelines say first choice BP drug for over 55’s is thiazide or CCB
3. I read a review in the BMJ last week that showed that showed thiazides gave better outcomes that ACEi in the elderly
4. Most people that I see in my surgery who have high BP seem to be on medication that includes a thiazide
5. That drug rep last week showed my some impressive graphs for his new CCB-thiazide combination drug
Rate these 5 fonts of wisdom in order of “good & sound”
![Page 13: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/13.jpg)
1. The NICE guidelines say first choice BP drug for over 55’s is thiazide or CCB
2. My GPR (who has just passed his MRCGP) says thiazides are good anti-hypertensives
3. I read a review in the BMJ last week that showed that showed thiazides gave better outcomes that ACEi in the elderly
4. Most people that I see in my surgery who have high BP seem to be on medication that includes a thiazide
5. That drug rep last week showed my some impressive graphs for his new CCB-thiazide combination drug
Rate these 5 fonts of wisdom in order of “good & sound”
Quality Data?
![Page 14: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/14.jpg)
1. The NICE guidelines say first choice BP drug for over 55’s is thiazide or CCB
2. I read a review in the BMJ last week that showed that showed thiazides gave better outcomes that ACEi in the elderly
3. My GPR (who has just passed his MRCGP) says thiazides are good anti-hypertensives
4. Most people that I see in my surgery who have high BP seem to be on medication that includes a thiazide
5. That drug rep last week showed my some impressive graphs for his new CCB-thiazide combination drug
Rate these 5 fonts of wisdom in order of “good & sound”
Quality Data?
![Page 15: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/15.jpg)
1. The NICE guidelines say first choice BP drug for over 55’s is thiazide or CCB
2. I read a review in the BMJ last week that showed that showed thiazides gave better outcomes that ACEi in the elderly
3. That drug rep last week showed my some impressive graphs for his new CCB-thiazide combination drug
4. Most people that I see in my surgery who have high BP seem to be on medication that includes a thiazide
5. My GPR (who has just passed his MRCGP) says thiazides are good anti-hypertensives
Rate these 5 fonts of wisdom in order of “good & sound”
Quality Data?
![Page 16: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/16.jpg)
1. The NICE guidelines say first choice BP drug for over 55’s is thiazide or CCB
2. I read a review in the BMJ last week that showed that showed thiazides gave better outcomes that ACEi in the elderly
3. That drug rep last week showed my some impressive graphs for his new CCB-thiazide combination drug
4. My GPR (who has just passed his MRCGP) says thiazides are good anti-hypertensives
5. Most people that I see in my surgery who have high BP seem to be on medication that includes a thiazide
Rate these 5 fonts of wisdom in order of “good & sound”
Quality Data?
![Page 17: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/17.jpg)
1. The NICE guidelines say first choice BP drug for over 55’s is thiazide or CCB
2. I read a review in the BMJ last week that showed that showed thiazides gave better outcomes that ACEi in the elderly
3. That drug rep last week showed my some impressive graphs for his new CCB-thiazide combination drug
4. My GPR (who has just passed his MRCGP) says thiazides are good anti-hypertensives
5. Most people that I see in my surgery who have high BP seem to be on medication that includes a thiazide
Rate these 5 fonts of wisdom in order of “good & sound”
Quality Data?
![Page 18: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/18.jpg)
Meta-analysis & systematic review – aggregation of several similar studies
Double-blind randomised placebo controlled studies Larger, generic products, paid for by neutral body
Double-blind randomised placebo controlled studiesSmaller, branded products, paid by the manufacturer
Observational studies
Case reports
Anecdotal experience
Big is Beautiful!
Good Studies & Bad studies – Study Hierarchy
Hierarchy of Evidence
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Big is Beautiful!
Hierarchy of Evidence
![Page 20: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/20.jpg)
Quality of Evidence - A,B C or D Grade A
Strong research-based evidence, at least one RCT, drawn from high quality scientific studies coming to same conclusions
Evidence levels:
Ia = randomised controlled trials
Ib = at least one randomised controlled trial
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Grade BModerate research-based evidence drawn from
well controlled studies.
Evidence levels:
IIa = at least one well-designed controlled study without randomisation
IIb = at least one other type of well-designed quasi experimental study
III = well-designed non-experimental descriptive studies.
Quality of Evidence - A,B C or D
![Page 22: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/22.jpg)
Grade CLimited research-based evidence drawn from
expert reports
Evidence level:
IV = expert committee reports or opinions and/or clinical experience of respected authorities
Grade D No scientific evidence.
Quality of Evidence - A,B C or D
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What sources do you use? Peers
Teaching session Asking your trainer
Daily Mail Journals Medical Text Books Drug Reps EBM Reference Books EBM Websites Internet - Google
How Good?Good but...
What do they really know?
No commentGood but hard to accessGood but out of dateYou must be joking...Good but out of date
Need to know...
Quality Sources of Data
![Page 24: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/24.jpg)
What sources do you use? Peers
Teaching session Asking your trainer
Daily Mail Journals Medical Text Books Drug Reps EBM Reference Books EBM Websites Internet - Google
How Good?Good but...
What do they really know?
No commentGood but hard to accessGood but out of dateYou must be joking...Good but out of date
Need to know...
Quality Sources of Data
![Page 25: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/25.jpg)
EBM Websites:
Centre for Reviews & Dissemination (CRD Uni York) – Database
NHS Evidence
Cochrane Library – Browse Database
TheNNT.com – Fun & more later…
BMJ Clinical Evidence – Subscription service (£150 per year)
Google Search? - Use Google Scholar
- Use Advanced Search
Quality Sources of Data
![Page 26: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/26.jpg)
Quality of data
Quality of sources of data
Let’s talk high quality…
![Page 27: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/27.jpg)
What on Earth Should We Try to Cover?
Why all the fuss granddad?- EBM is so yesterday….
The big issues: - quality, risk, wrong answers
Can you make it work?- CSA and real life
![Page 28: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/28.jpg)
Taking Risks
![Page 29: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/29.jpg)
Relative risk vs. Absolute riskOccurrence of Diabetic retinopathy among IDDM @5yrs in DCCT trial
Usual Regime Intensive Regime
38%(Control Event Rate)
13%(Experimental Event Rate)
Absolute Risk in intensive group = 13% Relative Risk in intensive group = 13/38 =
34% Relative Risk Reduction (RRR)
(CER-EER)/CER (38-13/38 = 25/38 = 66%) Absolute Risk Reduction (ARR)
EER-CER (13-38 = -25%)
Taking Risks
![Page 30: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/30.jpg)
Relative risk vs. Absolute riskAnnual Stroke Risk in High-risk AF Patients
Aspirin Warfarin
12%(Control Event Rate)
6%(Experimental Event Rate)
Absolute Risk in Aspirin group Relative Risk in Warfarin group Relative Risk Reduction (RRR)
(CER-EER)/CER Absolute Risk Reduction (ARR)
EER-CER
= 12%= 6/12 = 50%
12-6/12 = 6/12 = 50%
12-6 = -6%
Taking Risks
![Page 31: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/31.jpg)
Bluffer’s Guide to Risks
Relative Risk Used by drug companies to make their product
look good. Can make small numbers look bige.g. 0.002-0.001/0.002 = 50%
Absolute Risk Used to show how rare side effects are
Not simply absolute = goodrelative = bad
![Page 32: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/32.jpg)
Numbers Needed to Treat
The number of patients that need to be treated to create one additional favourable outcome Calculated as 1/ARR
(or how many ARRs are needed to make 100)
DCCT trial, ARR was 25 NNT is therefore 4 Treat 4 IDDM diabetes patients intensively for
5 years to prevent 1 diabetic retinopathy
Occurrence of Diabetic retinopathy among IDDM @5yrs in DCCT trial
Usual Regime Intensive Regime
38%(Control Event Rate)
13%(Experimental Event Rate)
![Page 33: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/33.jpg)
Bluffers Guide to NNT
The trendy statistic to ask for.Easy to understand & explain to patients
Lower numbers better! Still needs thinking about and evaluating
Remember the balance - NNH Rough Guide:
NNT under 10 “very, very interested” NNT 10-50-100 “probably, possibly” NNT over 100 “how much?????”
Look at TheNNT.com
![Page 34: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/34.jpg)
DBP 100-115. Any ideas about 5-year NNT? 5-year NNT is 120 Stroke-rate untreated = 2.4% (RRR 30%) Stroke rate treated = 1.6% ARR = 0.8%
What happens to 100 treated patients? How many would have had a stoke (untreated)? How many do have a stroke (treated)? In how many have you made a difference?
Statins & IHD risk? Any idea of NNTs?
NNT – Example with BP
![Page 35: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/35.jpg)
What on Earth Should We Try to Cover?
Why all the fuss granddad?- EBM is so yesterday….
The big issues: - quality, risk, wrong answers
Can you make it work?- CSA and real life
![Page 36: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/36.jpg)
Sense and Specificity
NOT a Jane Austen novel If only medical statistics made us so happy...
“It is a truth universally acknowledged, that a single man in possession of a good fortune, must be in want of a wife.”
Pride & PrejudiceJane Austen
![Page 37: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/37.jpg)
Sense and Specificity
Sensitivity = a/ a+cProportion of people with the target disorder who have a positive test
Specificity= d/ b+dProportion of people without the target disorder who have a negative test
True Diagnosis
Positive Negative
True Result
Positive a b
Negative c d
![Page 38: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/38.jpg)
Bluffers guide to Sense & Specificity
SnNout When a sign/test/symptom has a high
Sensitivity, a Negative result rules out the diagnosis.
SpPin When a test has a high Specificity, a Positive
result rules in the diagnosis.
![Page 39: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/39.jpg)
Memorise for the AKT....
True Diagnosis
Positive Negative
True Result
Positivea
(TP True Positive)
b(FP False Positive)
Type 1 error
Positive Predictive
ValuePPV = a/a+b
Negativec
(FN False Negative)
Type 2 error
d(TN True Negative)
Negative Predictive
ValueNPV = d/c+d
Sensitivitya/a+c
Specificityd/b+d
Sensitivity = a/ a+cProportion of people with the target disorder who have positive test
Specificity= d/ b+dProportion of people without the target disorder who have negative test
![Page 40: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/40.jpg)
Treatment? Test? Is it any use?
Your patients rely on your
knowledge and opinion as to
how useful a particular test/
treatment actually is
Treatment: NNT NNH
Tests: Spin & Snout
As useful as…
![Page 41: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/41.jpg)
What on Earth Should We Try to Cover?
Why all the fuss granddad?- EBM is so yesterday….
The big issues: - quality, risk, wrong answers
Can you make it work?- CSA and real life
![Page 42: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/42.jpg)
Disease- Illness Model (Stewart & Roter 1989)
![Page 43: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/43.jpg)
Is my practice evidence-based?Have you…
1. Identified and prioritised the clinical,
psychological, social and other problems,
taking into account the patient’s
perspective?
![Page 44: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/44.jpg)
And..
2. Performed a sufficiently competent and
complete examination to establish the
likelihood of competing diagnoses?
![Page 45: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/45.jpg)
And…
3. Considered additional problems and risk
factors?
![Page 46: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/46.jpg)
And….
4. Where necessary, sought relevant
evidence - from systematic reviews,
guidelines, clinical trials, and other
sources
![Page 47: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/47.jpg)
And…..
5. Assessed and taken into account the
completeness, quality and strength of the
evidence, and its relevance to this patient?
![Page 48: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/48.jpg)
And…...
6. Presented the pros and cons of the
different options to the patient in a way
they can understand, and incorporated the
patient’s preferences into the final
recommendations???
![Page 49: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/49.jpg)
Not asking much, are we?
Is my practice evidence-based?Can you do it ??????
“Why, when I was your
age, sometimes I've
believed as many as six
impossible things
before breakfast.”
The Queen of Hearts
Alice in Wonderland
![Page 50: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/50.jpg)
Patient Preferences in Treatment Decisions
Time for some role-play vignettes Split into 3 groups Take up the challenge:
Talking risks & NNT (NNH) Dodgy tests
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Patient Preferences in Treatment Decisions
Feedback from what you observedHow would you do this in the CSA?
Find out what the patients knows (wants to know) Avoid jargon Avoid percentages & fractions (100 people...) Use chunks & checks Remember patient autonomy... How do you cope with an unreasonable
expectation?
![Page 52: Evidence-based Practice Dr Christine Marshall Dr Richard de Ferrars Dr Andrew Cochrane Frimley VTS September 2014.](https://reader034.fdocuments.in/reader034/viewer/2022042608/56649e7e5503460f94b81033/html5/thumbnails/52.jpg)
The End