7/27/2019 Enterococcus or Group D Streptococci

1/9

GROUP D STREPTOCOCCUSEnterococcus faecalis &S. bovis

Dr.Aravind

7/27/2019 Enterococcus or Group D Streptococci

2/9

E. faecalis (Name-Derivation: feces)

S.bovis (bovine)

Part of the GIT normal flora

Gram-positive cocci in pairs or short chains

Catalase negative

Lancefield Group D specific cell wall carbohydrate teichoic acid antig

Facultative anaerobes

Halotolerant and Bile resistant

Dr.Aravind

7/27/2019 Enterococcus or Group D Streptococci

3/9

Epidemiology:

Endogenous in large intestine and animals

Food transmission

Nosocomial

Urinary or intravascular catheterization

Dr.Aravind

7/27/2019 Enterococcus or Group D Streptococci

4/9

Pathogenesis:

R plasmid

No potent virulenant factors

Colonization & secretory factors

Fibrinolytic

carbohydrate factors - adherence

Bacteriocins: Inhibit competitive bacteria

GIT colonization bacteremia Subacute endocardi

UTI

Dr.Aravind

7/27/2019 Enterococcus or Group D Streptococci

5/9

Clinical conditions:

Urinary tract infections

GIT diseases

Nosocomial Sub acute bacterial endocarditis

S.Bovis associated with colon cancer

Meningitis

Dr.Aravind

7/27/2019 Enterococcus or Group D Streptococci

6/9

Entry:

Endogenous, food

born and catheters

UTI

Dysuria, increased

frequency

GIT infections

Dysentery, abscess

etc

Sub acute endocarditis

1. Slow pace

2. Anemia

3. Roths spots

4. Splinter hem

5. Murmurs6. Emboli

7. Oslers node

Meningitis

Dr.Aravind

Clinical Conditions

7/27/2019 Enterococcus or Group D Streptococci

7/9

Splinter hemorrhages

Roths spots

Oslers n

Dr.Aravind

7/27/2019 Enterococcus or Group D Streptococci

8/9

Diagnosis:

Resemble S. pneumoniae in Gram stains

Growth Large white colonies

E. Faecalis blood agar with 40% bile & 6.5%Nacl

S.bovis blood agar with 40% bile and not with 6.5%Nacl

Hydrolysis of esculin to esculetin on BEA media Black discolo

Resistance to optochin

PYR +

Dr.Aravind

7/27/2019 Enterococcus or Group D Streptococci

9/9

Treatment:

Resistance R Plasmid

Ampicillin, Vancomycin, Pristinomycin

Dr.Aravind