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ThermodynamicsFundamentals for ApplicationsJohn P. O’ConnellUniversity of Virginia, CharlottesvilleJ.M. HaileMacatea Productions, Central, SC

Thermodynamics: Fundamentals forApplications is a text for a firstgraduate course in chemicalengineering. The focus is onmacroscopic thermodynamics;discussions of modeling andmolecular situations are integratedthroughout. Underpinning this textis the knowledge that, while thermodynamics describes naturalphenomena, those descriptions are the products of creative,systematic minds. Nature unfolds without reference to humanconcepts of energy, entropy, or fugacity. Natural complexity can beorganized and studied by thermodynamics methodology. Thepower of thermodynamics can be used to advantage if thefundamentals are understood. This text’s emphasis is onfundamentals rather than modeling. Knowledge of the basics willenhance the ability to combine them with models when applyingthermodynamics to practical situations. While the goal of anengineering education is to teach effective problem solving, this textnever forgets the delight of discovery, the satisfaction of graspingintricate concepts, and the stimulation of the scholarly atmosphere.

Contents:Introduction; Part I. The Basics: 1. Primitives; 2. The first and second laws;3. Fundamental relations; Part II. Single-Phase Systems: 4. Propertiesrelative to ideal gases; 5. Properties relative to ideal solutions; 6. Relationsamong relations; Part III. Multiphase and Reacting Systems: 7. Transfers,transformations, and equilibria; 8. Criteria for observability; 9. Phasediagrams for real systems; Part IV. Engineering Calculations: 10. Optionsfor equilibrium calculations; 11. Elementary computational procedures;12. Selected applications; Afterword; Appendices: A. Tools from thecalculus; B. Elements of linear algebra; C. Solutions to cubic equations; D.Vapor pressures of selected fluids; E. Model parameters for G excess; F. Astability condition for binaries; G. Notation in variational calculus; H.

Triangular diagrams; I. Lagrange multipliers; J. NRTL models; K. Simplealgorithms for binary VLLE; Notation; Index.2005/672 pp./148 line diagrams/24 tables58206-7/Hb/List: $100.00Disc.: $80.00

Forthcoming…

Systems BiologyProperties of Reconstructed NetworksBernhard Ø. PalssonUniversity of California, San Diego

Genome sequences are now available that enable us to determinethe biological components that make up a cell or an organism. Thenew discipline of systems biology examines how these componentsinteract and form networks, and how the networks generate wholecell functions corresponding to observable phenotypes. Thistextbook describes how to model networks, determine theirproperties, and relate these to phenotypic functions. Someknowledge of linear algebra and biochemistry is required, since thebook reflects the irreversible trend of increasing mathematicalcontent in biology education.

Contents:Preface; 1. Introduction; 2. Basic concepts in systems biology; Part I.Reconstruction of Biochemical Networks: 3. Metabolic networks; 4.Regulatory networks; 5. Signalling networks; Part II. MathematicalRepresentation of Reconstructed Networks: 6. Basic features of S; 7.Topological properties; 8. Fundamental subspaces; 9. Null space of S; 10.The left null space of S; 11. The row and column spaces of S; Part III.Capabilities of Reconstructed Networks: 12. Dual causality; 13. Propertiesof solution spaces; 14. Sampling properties of solution spaces; 15. Findingfunctional states; 16. Parametric sensitivity; 17. Epilogue; Appendix A.Nomenclature and abbreviations; Appendix B. E. coli core metabolicnetwork; Bibliography; Index.2006/c. 320 pp.85903-4/Hb/List: $75.00*Disc.: $60.00*

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Models of Cell MechanicsEditorsRoger KammMassachusetts Institute of TechnologyMohammad Kaazempur-MofradUniversity of California, Berkeley

Roger Kamm and Mohammad Kaazempur-Mofradcollaborated with a group of experts on their newbook, Models of Cell Mechanics. All of the editorsand contributors, with backgrounds ranging frombiophysics to bioengineering to biochemistry, arewidely-published, renowned experts. They have allcontributed chapters, producing a book thatconveys the many and varied perspectives andapproaches that researchers have developed toprobe, model, and describe the cytoskeleton of acell. The style and content are both accessible tothe novice and essential for the specialist. Kammand Kaazempur-Mofrad begin by introducing thebasic concepts necessary to understand thedifferent approaches; they close with a final chapterthat summarizes, and reconciles, these diverse viewsof cell mechanics, pointing to accomplishmentsand challenges that students and researchers facenow and for the future.

Contents and Contributors:1. Introduction: State of the art in modeling cellmechanics M. Kaazempur-Mofrad and R. Kamm; 2.Experimental measurements of intracellular mechanics P.Janmey and C. Schmidt; 3. The cytoskeleton as a softglassy material J. Fredberg and B. Fabry; 4. Elastic orviscoelastic continuum models M. Kaazempur-Mofrad,H. Karcher, and R. Kamm; 5. Multiphasic models of cellmechanics F. Guilak, M. A. Haider, L. A. Setton, T. A.Laursen, and F. P. T. Baaijens; 6. Descriptions ofcytoskeletal mechanics based on the concept of tensegrityD. Stamenovic; 7. Cells, gells, and mechanics G. H.Pollack; 8. Polymer physics and cytoskeletal networks F.MacKintosh; 9. The polymerization dynamics of actinnetworks within cells J. L. McGrath and C. F. Dewey, Jr.;10. Active cellular protrusion M. Herant and M.Dembo; 11. Summary: A unifying viewpoint M.Kaazempur-Mofrad and R. Kamm2006/c. 500 pp.84637-4/Hb/List: $90.00*Disc.: $72.00*

Van der Waals ForcesA Handbook for Biologists,Chemists, Engineers and PhysicistsV. Adrian ParsegianNational Institutes of Health, Bethesda, MD

This should prove to be the definitive workexplaining van der Waals forces, how to calculatethem and take account of their impact under anycircumstances and conditions. These weakintermolecular forces are of truly pervasive impact,and biologists, chemists, physicists, and engineerswill profit greatly from the thorough grounding inthese fundamental forces. Parsegian has organizedhis book at three successive levels of mathematicalsophistication, to satisfy the needs and interests ofreaders at all levels of preparation. The Prelude andLevel 1 are intended to give everyone an overviewin words and pictures of the modern theory of vander Waals forces. Level 2 gives the formulae and awide range of algorithms to let readers compute thevan der Waals forces under virtually any physical orphysiological conditions. Level 3 offers a rigorousbasic formulation of the theory.2005/400 pp.83906-8/Hb/List: $110.00Disc.: $88.0054778-4/Pb/List: $50.00Disc.: $40.00

Principles andTechniques ofBiochemistry andMolecular BiologySixth EditionEditors Keith WilsonUniversity of Hertfordshire, UKJohn WalkerUniversity of Hertfordshire

“It is necessary to have a practical, up to date guide toexperimental techniques at hand in a laboratory. Thisbook belongs to such kind of texts. It covers all branchesof basic as well as advanced techniques. The bookrepresents a fundamental guidebook for work in alaboratory.”

—Photosynthetica

This new and expanded edition of the bestsellingtextbook has now been fully revised to includetechniques from across the biosciences. It focusesparticularly on those techniques that have led torecent advances in molecular biology and is designedto help students understand the theory and practicalprinciples behind those methods. The book will beessential reading for all bioscience undergraduatestudents and pre-clinical medical students.

Contents and Contributors:Preface; List of contributors; List of abbreviations; 1.Basic principles Keith Wilson and John Fyffe; 2. Cell


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culture techniques Anwar R. Baydoun; 3.Centrifugation Kay Ohlendieck; 4. MicroscopyStephen W. Paddock; 5. Molecular biology,bioinformatics and basic techniques RalphRapley; 6. Recombinant DNA and geneticanalysis Ralph Rapley; 7. Immunochemicaltechniques Robin Thorpe and Susan Thorpe; 8.Protein structure, purification, characterisationand functional analysis John Walker; 9. Massspectrometric techniques Alistair Aitken; 10.Electrophoretic techniques John Walker; 11.Chromatographic techniques Keith Wilson; 12.Spectroscopic techniques I: atomic andmolecular electronic spectroscopy Derek B.Gordon; 13. Spectroscopic techniques II:vibrational spectroscopy and electron andnuclear spin orientation in magnetic fields; 14.Radioisotope techniques Robert J. Slater; 15.Enzymes Keith Wilson; 16. Cell membranereceptors and cell signalling Keith Wilson.2005/802 pp./5 color plates/34 halftones/287 linediagrams/66 tables82889-9/Hb/List: $140.00Disc.: $112.0053581-6/Pb/List: $70.00Disc.: $56.00

StatisticalThermodynamicsFundamentals andApplicationsNormand M. LaurendeauPurdue University, West Lafayette, IN

Building on the Maxwell-Boltzmannmethod of step-by-step development of thesubject, this book makes few presumptionsconcerning students’ previous exposure tostatistics, quantum mechanics, orspectroscopy. The book begins with thefundamentals of statisticalthermodynamics, pauses to recover neededknowledge from quantum mechanics andspectroscopy, and then moves on toapplications involving ideal gases, the solidstate, and radiation. A full introduction tokinetic theory is provided, including itsapplications to transport phenomena andchemical kinetics. Modern applications,such as laser-based diagnostics, are alsodiscussed.

Contents:1. Introduction; I. Fundamentals of StatisticalThermodynamics: 2. Probability and statistics;Problem Set I: Probability theory and statisticalmathematics; 3. The statistics of independentparticles; 4. Thermodynamics properties in thedilute limit; Problem Set II: Statistical modelingfor thermodynamics; II. Quantum Mechanicsand Spectroscopy: 5. Basics of quantummechanics; 6. Quantum analysis of internalenergy modes; 7. The spectroscopy of diatomicmolecules; Problem Set III: Quantum mechanicsand spectroscopy; 8. Interlude: From Particle to

Assembly; 9. Thermodynamic properties of theideal gas; Problem Set IV: Thermodynamicproperties of the ideal gas; 10. Statisticalthermodynamics for ideal gas mixtures; 11.Concentration and temperature measurements;Problem Set V: Chemical equilibrium anddiagnostics; IV. Statistical ThermodynamicsBeyond the Dilute Limit: 12. Thermodynamicsand information; 13. Elements of the solid state;14. Equilibrium radiation; Problem Set VI: Thesolid state and radiation; V. Non-EquilibrumStatistical Thermodynamics: 15. Elementarykinetic theory; 16. Kinetics of moleculartransport; 17. Chemical kinetics; Problem SetVII: Kinetic theory and molecular transport; VI.The Ensemble Method of StatisticalThermodynamics: 18. The canonical and grandcanonical ensembles; 19. Applications ofensemble theory to real gases; Problem Set VIII:Ensemble theory and the non-ideal gas; 20.Whence and whither; VII. Appendices2005/464 pp./92 line diagrams/64 tables84635-8/Hb/List: $90.00Disc.: $72.00

Numerical Methods inEngineering withMATLAB®

Jaan KiusalaasPennsylvania State University, State College

Numerical Methods in Engineering withMATLAB® is a text for engineering studentsas well as a reference for practicingengineers, especially those who wish toexplore the power and efficiency ofMATLAB®. The choice of numericalmethods was based on their relevance toengineering problems. Each method isdiscussed thoroughly and illustrated withproblems involving both hand computationand programming. MATLAB® filesaccompany each method and are availableon the book web site. MATLAB® waschosen as the example language because ofits universal use in engineering studies andpractice.

Contents:1. Introduction to MATLAB; 2. Systems oflinear algebraic equations; 3. Interpolation andcurve fitting; 4. Roots of equations; 5.Numerical differentiation; 6. Numericalintegration; 7. Initial value problems; 8. Two-point boundary value problems; 9. SymmetricMatrix Eigenvalue problems; 10. Introductionto optimization; Appendices.2005/432 pp./133 line diagrams/12 tables85288-9/Hb/List: $85.00Disc.: $68.00

Also available with Python code…

Numerical Methods inEngineering with PythonJaan Kiusalaas2005/432 pp./133 line diagrams/12 tables85287-0/Hb/List: $85.00Disc.: $68.00

Valency and BondingA Natural Bond Orbital Donor-Acceptor PerspectiveFrank WeinholdUniversity of Wisconsin, MadisonClark LandisUniversity of Wisconsin

This textbook develops the foundations ofLewis- and Pauling-like localized structuraland hybridization concepts to present thefirst modernized overview of chemicalvalency and bonding theory. Directly basedon current computational technology, itserves as both a general textbook expositionof modern Lewis, hybridization, andresonance concepts and a comprehensivecompilation of NBO-based bondingdescriptors—for prototype molecular andsupramolecular organic and inorganicspecies.

Contents:Part I. Introduction and TheoreticalBackground: 1. The Schrödinger equation andmodels of chemistry; 2. Hydrogen atom orbitals;



3. Many-electron systems; 4.Perturbation theoryfor orbitals in the Hartree-Fock framework: thedonor-acceptor paradigm; 5. Density matrices,natural localized and delocalized orbitals and theLewis structure picture; 6. Natural resonancestructures and weightings; 7. Pauli exchangeantisymmetry and steric repulsions; 8.Summary; Part II. Electrostatic and IonicBonding: 1. Introduction; 2. Atomic and ionicorbitals; 3. Charge transfer and hybridizationchanges in ionic bonding; 4. Donor-acceptortheory of hybridization changes in ionicbonding; 5. Ionic/covalent transitions; 6. Ion-dipole and dipole-dipole bonding; 7. Beta ioniccompounds of heavy alkaline earths; 8. Ionicbonding in D-block elements; 9. Summary; PartIII: Molecular Bonding in the S/P-BlockElements: 1. Introduction; 2. Covalent andpolar covalent bonding; 3. Conjugation andaromaticity; 4. Hyperconjugation; 5.Hypervalency; 6. Hypovalency; 7. Summary;Part IV. Molecular Bonding in the D-BlockElements: 1. Introduction; 2. Lewis-likestructures for the D-block; 3. Hybridization andmolecular shape; 4. Covalent and polar covalentbonding; 5. Coordinative metal-ligand bonding;6. Hypervalent bonding; 7. Hypovalency andagostic interactions; 8. Conjugative andhyperconjugative effects; 9. Multi-electroncoordination; 10. Vertical trends in transitionmetal bonding; 10. Summary. Part V.Supramolecular Bonding: 1. Introductoryoverview of intermolecular forces; 2. Hydrogenbonding; 3. Charge transfer complexes; 4.Transition state species; 5. Coupling of intra-and intermolecular interactions; 6. Summary;Appendices2004/760 pp./19 halftones/307 line diagrams83128-8/Hb/List: $110.00Disc.: $88.00

BiomedicalEngineering

BiomechanicsFrom Cells to OrganismsC. Ross EthierUniversity of TorontoCraig A. SimmonsUniversity of Pennsylvania

This introductory textbook is written forsenior level undergraduates and junior levelgraduate students taking a first course inbiomechanics and/or biomechanicalengineering. It teaches students how toapply the principles of mechanics to livingsystems. The systems discussed are drawnfrom widely different parts of nature andoccur at all scales, ranging from subcellularcytoskeletal mechanics to cell motion incapillaries to terrestrial locomotion. The

book includes a large selection of problemsto aid student understanding.

Contents:1. Introduction; 2. Cellular biomechanics; 3.Hemodynamics, 4. The circulatory system; 5.The interstitium; 6. Ocular biomechanics; 7.The respiratory system; 8. The renal system; 9.Muscles and movement; 10. Skeletalbiomechanics; 11. Terrestrial locomotion;References; Appendix A2006/c.450pp84112-7/Hb/List: $95.00*Disc.: $76.00*

Forthcoming…

Basic BiotechnologyThird EditionEditors Colin RatledgeUniversity of Hull, UKBjørn KristiansenEU Biotech Consulting

Biotechnology’s wide-ranging, multi-disciplinary activities include recombinantDNA techniques, cloning, and theapplication of microbiology to theproduction of goods from bread toantibiotics. In this new edition, biology andbioprocessing topics are uniquely combinedto provide a complete overview ofbiotechnology. A distinctive feature of thetext is the discussions of the publicperception of biotechnology and thebusiness of biotechnology, which set thescience in a broader context. Thiscomprehensive textbook is essential readingfor all students of biotechnology andapplied microbiology, and for researchers inbiotechnology industries.

Contents and Contributors:1. Public perception of biotechnology J. E.Smith; 2. Biochemistry and physiology ofgrowth and metabolism Colin Ratledge; 3.Stoichiometry and kinetics of microbial growthfrom a thermodynamic perspective J. J. Heijnen;4. Genome management and analysis:prokaryotes Colin R. Harwood and Anil Wipat;5. Genetic engineering: yeasts and filamentousfungi David B. Archer, Donald A. MacKenzieand David J. Jeenes; 6. Microbial processkinetics Jens Nielsen; 7. Bioreactor design YusufChisti; 8. Mass transfer Henk J. Noorman; 9.Downstream processing Marcel Ottens,Johannes A. Wesselingh and Luuk A. M. van derWielen; 10. Measurement, monitoring,modelling and control Bernhard Sonnleitner;11. Process economics Bjørn Kristiansen; 12.High throughput screening and processoptimisation Steven D. Doig, Frank Baganz andGary J. Lye; 13. The business of biotechnologyJason Rushton and Chris Evans; 14. Aminoacids L. Eggeling, W. Pfefferle and H. Sahm; 15.

Organic acids Christian P. Kubicek and LeventeKaraffa; 16. Microbial polysaccharides andsingle cell oils James P. Wynn; 17.Environmental applications PhilippeVandevivere and Willy Verstraete; 18.Production of antibiotics by fermentation DerekJ. Hook; 19. Strategies of cultivation Sven-OlofEnfors; 20. Enzyme biotechnology Randy M.Berka and Joel R. Cherry; 21. Recombinantproteins of high value Georg-B. Kresse; 22.Insect and mammalian cell culture C. J. Hewitt,B. Isailovic, N. T. Mukwena and A. W. Nienow;23. Plant cell biotechnology Robert Verpoorteand Hens J.G. ten Hoopen; 24.Biotransformations Pedro Fernandes andJoaquim M. S. Cabral; 25. Immunochemicalapplications M. Clarke.2006/c. 608 pp./15 halftones/250 line diagrams/94tables84031-7/Hb/List: $120.00*Disc.: $96.00*54958-2/Pb/List: $60.00*Disc.: $48.00*

BiotechnologyFourth EditionJohn E. SmithUniversity of Strathclyde, Glasgow, Scotland, UK

In this expanded fourth edition of hispopular textbook, John Smith once againdemystifies biotechnology—especiallygenetic manipulation—by clearly andaccessibly explaining the history, techniques,and applications of modern biotechnologyfor students and the general reader. Allaspects of biotechnology are covered, and apositive stance is taken concerning thepotential benefits to human society. Greateremphasis is also given to the publicperception of biotechnology and the ethicaland safety questions raised. The book isideal for short introductory biotechnologycourses at the university level.



Contents:Preface; 1. The nature of biotechnology; 2. Substrates forbiotechnology; 3. Genetics and biotechnology; 4.Bioprocess and fermentation technology; 5. Enzymetechnology; 6. Biological fuel generation; 7. Single cellprotein (SCP); 8. Biotechnology and medicine; 9.Environmental biotechnology; 10. Biotechnology in theagro and forestry industries; 11. Food and beveragebiotechnology; 12. Protection of biotechnologicalinventions; 13. Safety in biotechnology; 14. Publicperception of biotechnology: genetic engineering—safety, social, moral and ethical considerations; 15.Looking to the future; Glossary; Further reading; Index.

Studies in Biology

2004/284 pp./3 halftones/50 figures/47 line diagrams83332-9/Hb/List: $80.00Disc.: $64.0054077-1/Pb/List: $29.99Disc.: $23.99

An Introduction toGenetic EngineeringSecond EditionDesmond S.T. NichollUniversity of Paisley, Scotland, UK

“Nicholl’s short treatise, written in a relaxed,conversational tone, bridges the gap between theoryand practice. An easy-to-follow narrative,accompanied by simple, clear diagrams, provides theinterested student with the background needed tounderstand where restriction enzymes come from, theprinciples of gene cloning and expression, how DNaseI footprinting works, how to make a transgenicanimal, etc. The book, therefore, fills an importantniche and should be brought to the attention of upper-level undergraduate students and beginning graduatestudents in any branch of biology that makes use ofmolecular techniques.”

—ASM News

Des Nicholl presents a new, fully revised, andexpanded edition of his popular undergraduate-level textbook. The book retains many of thefeatures of the original edition and still offers aconcise technical introduction to the subject ofgenetic engineering. It is divided into three mainsections: basic molecular biology, methods of genemanipulation, and modern applications of geneticengineering. Applications covered in the bookinclude genomics, protein engineering, genetherapy, cloning, transgenic animals and plants,and bioethics. An Introduction to GeneticEngineering is essential reading for undergraduatestudents of biotechnology, genetics, molecularbiology, and biochemistry.

Contents:Preface to the second edition; 1. Introduction; Part I.The Basis of Genetic Engineering: 2. Introducingmolecular biology; 3. Working with nucleic acids; 4. Thetools of the trade; Part II. The Methodology of GeneManipulation: 5. Host cells and vectors; 6. Cloningstrategies; 7. The polymerase chain reaction; 8. Selection,

screening, and analysis of recombinants; Part III. GeneticEngineering in Action: 9. Understanding genes andgenomes; 10. Genetic engineering and biotechnology;11. Medical and forensic applications of genemanipulation; 12. Transgenic plants and animals; 13.The other sort of cloning; 14. Brave new world orgenetic nightmare?; Suggestions for further reading;Using the World Wide Web; Glossary; Index

Studies in Biology

2002/304 pp./11 halftones/121 figures/111 line diagrams/27tables80867-7/Hb/List: $70.00Disc.: $56.0000471-3/Pb/List: $30.00Disc.: $24.00

Physics in Molecular BiologyKim Sneppen Niels Bohr Institutet, CopenhagenGiovanni Zocchi University of California, Los Angeles

Tools developed by statistical physicists are ofincreasing importance in the analysis of complexbiological systems. Physics in Molecular Biologydiscusses how physics can be used in modeling life.It begins by summarizing important biologicalconcepts, emphasizing how they differ from thesystems normally studied in physics. A variety oftopics, ranging from the properties of singlemolecules to the dynamics of macro-evolution, arestudied in terms of simple mathematical models.The main focus of the book is on genes andproteins and how they build systems that computeand respond. The discussion develops from simpleto complex systems, and from small-scale to large-scale phenomena. This book will inspire advancedundergraduates and graduate students to approachbiological subjects from a physicist’s point of view.It is self-contained, requiring no backgroundknowledge of biology, and only familiarity withbasic concepts from physics, such as forces, energy,and entropy.

Contents:1. What is special about living matter; 2. Polymerphysics; 3. DNA and RNA; 4. Protein structure; 5.Protein folding; 6. Proteins in action: molecular motors;7. Physics of genetic regulation: the l-phage; 8.Molecular networks; 9. Evolution.2005/320pp./100 halftones/80 line diagrams84419-3/Hb/List: $70.00Disc.: $56.00



Forthcoming…

Methods in Molecular BiophysicsStructure, Dynamics, FunctionIgor N. Serdyuk Institute of Protein Research, MoscowNathan R. Zaccai University of CambridgeJoseph Zaccai Institut Laue Langevine, Grenoble

Our knowledge of biological macromolecules andtheir interactions is based on the application ofphysical methods, ranging from classicalthermodynamics to recently developed techniquesfor the detection and manipulation of singlemolecules. These methods, which include massspectrometry, hydrodynamics, microscopy,diffraction and crystallography, electronmicroscopy, molecular dynamics simulations, andnuclear magnetic resonance, are complementary;each has its specific advantages and limitations.Organized by method, this textbook providesdescriptions and examples of applications for thekey physical methods in modern biology. It is aninvaluable resource for undergraduate and graduatestudents of molecular biophysics in science andmedical schools, as well as research scientistslooking for an introduction to techniques beyondtheir specialty. As appropriate for thisinterdisciplinary field, the book includes shortasides to explain physics aspects to biologists andbiology aspects to physicists.

Contents:Foreword; Preface; A. Biological macromolecules andphysical tools; B. Mass spectroscopy; C.Thermodynamics; D. Hydrodynamics; E. Opticalspectroscopy; F. Optical microscopy; G. X-ray andneutron diffraction; H. Electron diffraction; J. Moleculardynamics; K. Nuclear magnetic resonance; References.2006/c. 900pp/400 line diagrams/150 color plates81524-X/Hb/List: $85.00*Disc.: $68.00*

Statistical Modeling for BiomedicalResearchersA Simple Introduction to the Analysis ofComplex DataWilliam D. DupontVanderbilt University, Nashville, TN

This text enables biomedical researchers to use anumber of advanced statistical methods that haveproven valuable in medical research, and uses astatistical software package (Stata®) to avoidmathematics beyond the high school level.Intended for people who have had an introductorycourse in biostatistics, the volume emphasizes theassumptions underlying each method, usingexploratory techniques to determine the mostappropriate method. It presents results in a waythat will be readily understood by clinical

colleagues. Numerous real examples from medicalliterature and graphical methods are used toillustrate these techniques.

Contents:Preface; 1. Introduction; 2. Simple linear regression; 3.Multiple linear regression; 4. Simple logistic regression;5. Multiple logistic regression; 6. Introduction to survivalanalysis; 7. Hazard regression analysis; 8. Introduction toPoisson regression; 9. Multiple Poisson regression; 10.Fixed effects analysis of variation; 11. Repeated-measuresanalysis of variation; Index.2003/404 pp./70 line diagrams/31 tables/74 exercises82061-8/Hb/List: $110.00Disc.: $88.0065578-1/Pb/List: $55.00Disc.: $44.00

Medical Statistics from A to ZA Guide for Clinicians and MedicalStudentsB.S. EverittUniversity of London, UK

“[An] excellent guide...The book is an excellentreference for doctors and students working in differentareas, such as the pharmaceutical industry,epidemiology, psychology or genetics. Readers with astronger background in applied statistics can get anexcellent overview of statistical terms in areas withwhich they may be unfamiliar. This book is definitelyworth including in a pharmaceutical library.”

—Pharmaceutical Statistics

From “absolute risk” to “zero-sum game”, thisaccessible introduction to the terminology ofmedical statistics encompasses more than 1500clearly explained terms. The definitions aredesigned to make this work a user-friendly guide tothe confusing world of medical statistics.Supplemented with suggested further reading andreferences, as well as helpful tips, this volume willenable doctors and medical students to quicklygrasp the meaning of the statistical terms theyencounter when reading medical literature.2003/236 pp./84 line diagrams82506-7/Hb/List: $90.00Disc.: $72.0053204-3/Pb/List: $39.99Disc.: $31.99



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Medical Implications of BiofilmsEditorsMichael WilsonUniversity of London, UKDeirdre DevineUniversity of Leeds

“I found this book a real pleasure to read, as it coversmany topics on medically important biofilms andadvancements in the prevention and treatment of suchdiseases. The book would be suitable for both cliniciansand medical researchers. The wide range of topicscovered makes this work a perfect review for thoseinterested in medically related biofilms.”

—ASM News

Interest in biofilms has increased dramatically inrecent years. New microscopic and moleculartechniques have revolutionized our understandingof biofilm structure, composition, organization,and activities. This book brings advances in theprevention and treatment of biofilm-relateddiseases to the attention of clinicians and medicalresearchers. Human tissues often support complexmicrobial communities growing as biofilms thatcan cause infections. As microbes in biofilmsexhibit increased tolerance toward anti-microbialagents and decreased susceptibility to host defensesystems, biofilm-associated diseases have becomeincreasingly difficult to treat.

Contents and Contributors:Part I. Introductory Chapters: 1.1 Biofilm-dependentregulation of gene expression P. LeJeune; 1.2 Quorumsensing and microbial biofilms T. R. de Kievit; 1.3Antimicrobial agents and biofilms M. R. Brown; Part II.Biofilms on Prosthetic Devices: 2.1 Animal models oforthopaedic implant infection Y. H. An; 2.2Intravascular-catheter-related infections H. A. Hanna;2.3 Molecular basis of biofilm formation bystaphylococcus epidermidis C. Heilmann; 2.4 Biofilmcomplications of urinary tract devices S. P. Gorman; PartIII. Oral Biofilms: 3.1 Novel microscopic methods tostudy the structure and metabolism of oral biofilms D.Bradshaw; 3.2 Oral streptococcal genes that encodebiofilm formation C. Y. Loo; 3.3 Gene expression in oralbiofilms R. A. Burne; Part IV. Biofilms on SheddingSurfaces: 4.1 Dissection of the genetic pathway leadingto multicellular behaviour in salmonella enterica serotypetyphimurium and other enterobacteriaceae U. Romling;4.2 Bacterial growth on mucosal surfaces and biofilms inthe large bowel G. T. Macfarlane; 4.3 Pseudomonasaeruginosa biofilms in lung infections K. K. Jefferson.2003/328 pp./28 halftones/17 line diagrams/17 tables81240-2/Hb/List: $110.00Disc.: $88.00

Microarray BioinformaticsDov StekelUniversity of Birmingham, UK

“...excellent and clearly written...concise and mostinformative, a pleasure to read. It should be examinedby anyone interested in this means of analysis.”

—ASM News

DNA microarrays have revolutionized molecularbiology and are becoming a standard tool in thefield. Dov Stekel’s book is a comprehensive guideto the mathematics, statistics, and computingrequired to use microarrays successfully. Unliketraditional molecular biology, the successful use ofDNA microarrays requires the application ofstatistics and computing to design the arrays andexperiments, and to analyze and manage the data.This book is written for researchers, clinicians, andlaboratory managers.

Contents:1. Microarrays: making them and using them; 2.Sequence databases for microarrays; 3. Computer designof oligonucleotide probes; 4. Image processing; 5.Normalization; 6. Measuring and quantifying microarrayvariability; 7. Analysis of differentially expressed genes; 8.Analysis of relationships between genes, tissues ortreatments; 9. Classification of tissues and samples; 10.Experimental design; 11. Data storage, standards andsharing; Appendix A. Glossary; Index.2003/280 pp./8 color plates/4 halftones/112 line diagrams/58tables81982-2/Hb/List: $120.00Disc.: $96.0052587-X/Pb/List: $48.00Disc.: $38.40

DNA Microarrays and GeneExpressionFrom Experiments to Data Analysis andModelingPierre BaldiUniversity of California, IrvineG. Wesley HatfieldUniversity of California

Massive data acquisition technologies—such asgenome sequencing, high-throughput drugscreening, and DNA arrays—are in the process ofrevolutionizing biology and medicine. Thisconcise, user-friendly and interdisciplinary guide toDNA microarray technology is an introductionand a reference for both biologists andcomputational scientists. The authors describe theunderlying technologies and offer an awareness ofthe “noise” and pitfalls present in the datagenerated. They also provide an idea of thedifferent data mining techniques and algorithmsthat are available to interpret data, and theadvantages and disadvantages of each in differingsituations.



Contents:Preface; 1. A brief history of genomics; 2. DNAarray formats; 3. DNA array readout methods;4. Gene expression profiling experiments:problems, pitfalls and solutions; 5. Statisticalanalysis of array data: inferring changes; 6.Statistical analysis of array data: dimensionalityreduction, clustering, and regulatory regions; 7.Survey of current DNA array applications; 8.Systems biology: overview of regulatory,metabolic and signaling networks.2002/230 pp./1 halftone/16 figures/16 line diagrams80022-6/Hb/List: $65.00Disc.: $52.00

Fundamental GeneticsJohn RingoUniversity of Maine, Orono

Organized for easy usage, forty-two mini-chapters begin with molecular structuresand progress through molecular processesto population genetics and evolution.Students will find the short, focusedchapters accessible and more easilyabsorbed than the longer and morecomplex chapters of traditional geneticstextbooks. Extensively illustratedthroughout with diagrams, thiscomprehensive textbook will provide acompact alternative for introductorygenetics courses.

Contents:1. Life forms and their origins; 2. Nucleic acids;3. Proteins; 4. Simple chromosomes; 5.Chromosomes of eukarya; 6. Genome content;7. RNA synthesis I: Transcription; 8. RNAsynthesis II: Processing; 9. Abundance of RNAsin bacteria; 10. Abundance of RNAs in eukarya;11. Protein synthesis; 12. DNA replication; 13.Chromosome replication; 14. Molecular eventsof recombination; 15. Micromutations; 16.Repair of altered DNA; 17. Reproduction ofbacteria; 18. Horizontal gene transfer inbacteria; 19. Cell cycles of eukarya; 20. Meiosis;21. Chromosomal abnormalities; 22. Life cyclesof eukarya; 23. Reproduction of viruses; 24.Genetic processes in development; 25. Sexdetermination and dosage compensation; 26.

Cancer; 27. Cutting, sorting, and copyingDNA; 28. Genotyping by DNA analysis; 29.Genetically engineered organisms; 30.Genomics; 31. Behavior of genes and alleles; 32.Probability and statistics toolkit; 33. Genes,environment, and interactions; 34. Locatinggenes; 35. Finding and detecting mutations; 36.Cytoplasmic inheritance; 37. Genetic variationin populations; 38. Mutation, migration, andgenetic drift; 39. Natural selection; 40.Quantitative genetics; 41. Speciation; 42.Molecular evolution and phylogeny; Glossary;2004/476 pp./272 line diagrams80934-7/Hb/List: $110.00Disc.: $88.0000633-3/Pb/List: $50.00Disc.: $40.00

Mechanics of the CellDavid BoalSimon Fraser University, British Columbia

Aimed at senior undergraduates andgraduate students in science and biomedicalengineering, this text explores thearchitecture of a cell’s envelope and internalscaffolding, and the properties of its softcomponents. The book first discusses theproperties of individual flexible polymers,networks and membranes, and thenconsiders simple composite assemblagessuch as bacteria and synthetic cells. Theanalysis is performed within a consistenttheoretical framework, although readers cannavigate from the introductory material toresults and biological applications withoutworking through the interveningmathematics. This, together with a glossaryof terms and appendices providing quickintroductions to chemical nomenclature,cell structure, statistical mechanics, andelasticity theory, make the text suitable forreaders from a variety of subjectbackgrounds. Further applications andextensions are handled through problemsets at the end of each chapter andsupplementary material available on theInternet.

Contents:1. Introduction to the cell; Part I. Rods andRopes: 2. Polymers; 3. Two-dimensionalnetworks; 4. Three-dimensional networks; PartII. Membranes: 5. Biomembranes; 6. Membraneundulations; Part III. The whole cell: 7. Thesimplest cells; 8. Intermembrane forces; 9.Dynamic filaments; 10. Mechanical designs;Appendix A. Animal cells and tissues; AppendixB. The cell’s molecular building blocks;Appendix C. Elementary statistical mechanics;Appendix D. Elasticity; References; Index.2002/420 pp./38 halftones/235 line diagrams/14tables79258-4/Hb/List: $130.00Disc.: $104.0079681-4/Pb/List: $65.00Disc.: $52.00

Biological ThermodynamicsDonald HaynieUniversity of ManchesterInstitute of Science andTechnology, UK

“In my opinion, the author has covered atraditionally boring field with vividdescription and interesting examples. Myoverall impression is that this book iscomprehensive, illustrative and up-to-date...Iwould certainly recommend it to my graduatestudents.”

—Yigong Shi, Princeton University

Biological Thermodynamics provides anintroduction to the study of energytransformations for students of thebiological sciences. Donald Haynie uses aninformal writing style to introduce this coresubject in a manner that will appeal tobiology and biochemistry undergraduatestudents. The emphasis of the text is placedon understanding basic concepts anddeveloping problem-solving skillsthroughout the text. The level ofmathematical complexity is kept to aminimum. Each chapter providesnumerous examples taken from differentareas of biochemistry, as well as extensiveexercises to aid understanding.

Contents:1. Energy transformation; 2. The first law ofthermodynamics; 3. The second law ofthermodynamics; 4. Gibbs free energy - theory;5. Gibbs free energy - applications; 6. Statisticalthermodynamics; 7. Binding equilibria; 8.Reaction kinetics; 9. The frontier of biologicalthermodynamics; Appendices; Glossary.2001/396 pp./126 figures/128 line diagrams/25tables79165-0/Hb/List: $95.00Disc.: $76.0079549-4/Pb/List: $45.00Disc.: $36.00



Skeletal Function and FormMechanobiology of Skeletal Development,Aging, and RegenerationDennis R. CarterStanford UniversityGary S. BeaupréVA Palo Alto Health Care System

“A very detailed treatment of skeletal tissues anddevelopmental mechanics. It is perfectly suited forstudents of functional anatomy or bioengineering, andthose engaged in applied biomedical pursuits....Skeletal Function and Form is a beautifully executedbook that sticks to the point and makes its case. Thereader is treated to a solid base of information thatclarifies how mechanical factors impact development,and how function determines form. The book is wellwritten and wonderfully illustrated, and it deserves ahome on the bookshelf of anyone curious about thestructure of the vertebrate skeleton.”

—Palaios

The intimate relationship between form andfunction inherent in the design of animals isperhaps nowhere more evident than in themusculoskeletal system. This book, about howfunction determines form, addresses the role ofmechanical factors in the development, adaptation,maintenance, aging, and repair of skeletal tissues.The authors refer to this process asmechanobiology and develop their theme withinan evolutionary framework. They show howdegenerative disorders such as arthritis andosteoporosis are regulated by the same mechanicalprocesses that influence normal development andgrowth. Skeletal Function and Form bridgesimportant gaps among disciplines, providing acommon ground for a multidisciplinaryunderstanding.

Contents:Preface; 1. Form and function; 2. Skeletal tissuehistomorphology and mechanics; 3. Cartilagedifferentiation and growth; 4. Perichondral andperiosteal ossification; 5. Endochondral growth andossification; 6. Cancellous bone; 7. Skeletal tissueregeneration; 8. Articular cartilage development anddestruction; 9. Mechanobiology in skeletal evolution; 10.The physical nature of living things; Appendix A.Material characteristics; Appendix B. Structuralcharacteristics; Appendix C. Failure characteristics.2000/330 pp./51 halftones/162 line diagrams79000-X/Hb/List: $95.00Disc.: $76.00

Chemical Engineering

Fundamentals of MultiphaseFlowChristopher E. BrennenCalifornia Institute of Technology, Pasadena

Multiphase flows are flows of mixtures of separatesubstances, such as bubbles of gas in liquids, orsolid particles in air. They are abundant in natureand in industrial processes, and the number ofcontexts in which one must be able to analyze andpredict their behavior is immense. This bookprovides a coherent and unified treatment ofmultiphase flows with an emphasis on theunderlying physical phenomena. It is targeted tograduate students and researchers at the cuttingedge of investigations into the fundamental natureof multiphase flows.

Contents:1. Introduction to multiphase flow; 2. Single particlemotion; 3. Bubble or droplet translation; 4. Bubblegrowth and collapse; 5. Cavitation; 6. Boiling andcondensation; 7. Flow patterns; 8. Internal flow energyconversion; 9. Homogenous flows; 10. Flows withbubble dynamics; 11. Flows with gas dynamics; 12.Sprays; 13. Granular flows; 14. Drift flux models; 15.System instabilities; 16. Kinematic waves.2005/368 pp./26 halftones/166 line diagrams/3 tables84804-0/Hb/List: $95.00Disc.: $76.00

Measurement in FluidMechanicsStavros TavoularisUniversity of Ottawa, Ontario, Canada

This is an ideal textbook and reference inexperimental fluid mechanics for anyone wishingto understand the properties of fluid-containingsystems, to design improved systems, to predict theoperation of such fluid systems, and to monitorand control physical processes. This single-authored book provides a consistent description ofmost available measurement methods, with thenecessary background material required tounderstand these methods. It contains classical andstate-of-the-art methods for flow visualization andfor measuring flow rate, pressure, velocity,temperature, concentration, and wall shear stress.While practicing engineers will find the bookuseful, it is ideal as a graduate textbook, withplenty of illustrations, an extensive bibliographyand suggested homework problems. Measurementin Fluid Mechanics contains extensive backgroundmaterial in system response, measurementuncertainty, signal analysis, optics, fluid mechanicalapparatus and laboratory practices, with theobjective to shield the reader from having to



An asterisk (*) denotes thatprices are subject to change.

Forthcoming books may be ordered now for shipment when available.

consult additional primary references.

Contents:Part I. General Concepts: 1. Flow properties and basicprinciples; 2. Measuring systems; 3. Measurementuncertainty; 4. Signal conditioning, discretization andanalysis; 5. Background for optical experimentation; 6.Fluid mechanical apparatus; 7. Towards a soundexperiment; Part II. Measurement Techniques: 8.Measurement of flow pressure; 9. Measurement of flowrate; 10. Flow visualization techniques; 11. Measurementof local flow velocity; 12. Measurement of temperature;13. Measurement of composition; 14. Measurement ofwall shear stress; 15. Outlook.2005/384 pp./3 halftones/97 line diagrams/21 tables81518-5/Hb/List: $85.00Disc.: $68.00

Introduction to ComputationalFluid DynamicsAnil W. DateIndian Institute of Technology,Bombay

This is a textbook for advancedundergraduate and first-year graduate students inmechanical, aerospace, and chemical engineering.The book emphasizes understanding CFD throughphysical principles and examples. The authorfollows a consistent philosophy of control volumeformulation of the fundamental laws of fluidmotion and energy transfer, and introduces a novelnotion of ‘smoothing pressure correction’ forsolution of flow equations on collocated gridswithin the framework of the well-known SIMPLEalgorithm. The subject matter is developed byconsidering pure conduction/diffusion, convectivetransport in 2-dimensional boundary layers and infully elliptic flow situations and phase-changeproblems in succession. The book includes chapterson discretization of equations for transport of mass,momentum and energy on Cartesian, structuredcurvilinear and unstructured meshes, solution ofdiscretised equations, numerical grid generationand convergence enhancement. Practicingengineers will find this particularly useful forreference and for continuing education.

Contents:Preface; Nomenclature; 1. Introduction; 2. 1D heatconduction; 3. 1D conduction-convection; 4. 2Dboundary layers; 5. 2D convection—Cartesian Grids; 6.2D convection—complex domains; 7. Phase change; 8.Numerical grid generation; 9. Convergenceenhancement; Appendix A: Derivation of transportequations; Appendix B: 1D Conduction code; AppendixC: 2D Cartesian code2005/400 pp./131 line diagrams/35 tables85326-5/Hb/List: $80.00Disc.: $64.00

Suspension AcousticsAn Introduction to the Physicsof SuspensionsSamuel TemkinRutgers University, New Brunswick, NJ

Suspension Acoustics: An Introduction to the Physicsof Suspensions is an introduction to the physics ofsuspensions of bubbles, droplets, and solid particlesin both gases and fluids. Rather than treating eachcombination separately, a unified approach is usedthat permits most particle-fluid combination typesto be discussed together. To do this, the book firstpresents a detailed discussion of the basic particlemotions that small particles can sustain, payingparticular attention to translations and pulsations,and to the thermal effects that occur as a result ofthose motions. The book then introduces thereader to the dynamics and thermodynamics ofsuspensions, with acoustic motions providing themain focus in the latter part of the book. Theimportant acoustic problems of attenuation anddispersion are discussed from several fundamentalperspectives. The book concludes with applicationsof acoustic techniques to the characterization andmodification of suspensions by means of acousticwaves.

Contents:1. Preliminaries; 2. Conservation equations; 3. Rigidparticle heat transfer at Re; 4. Translation motion at Re;5. Shape deformations; 6. Volume pulsations; 7.Thermodynamics of suspensions; 8. The two phasemodel; 9. Sound propagation in suspensions; 10.Application and extensions.2005/432 pp./4 halftones/142 line diagrams/10 tables84757-5/Hb/List: $110.00Disc.: $88.00

Large-Eddy Simulations ofTurbulenceMarcel LesieurLaboratoire des Ecoulements, Grenoble, FranceOlivier MétaisLaboratoire des EcoulementsPierre ComteLaboratoire des Ecoulements

This volume is an ideal introduction and referenceto LES, direct numerical simulation, andReynolds-averaged Navier-Stokes simulation. Thetext features a detailed discussion of vorticity,pressure, and the velocity gradient tensor, and anin-depth discussion of spectral subgrid-scalemodeling. These spectral models give insight intothe requirements and limitations in subgrid-scalemodeling and backscattering. The text also featuresa discussion of large-eddy simulation ofcompressible flows previously only availablescattered throughout the literature; this will be ofinterest to those dealing with supersonic flows,combustion, astrophysics, and related topics.



Contents:1. Introduction to LES; 2. Vortex dynamics; 3. LESformalism in physical space; 4. Spectral LES for isotropicturbulence; 5. Spectral LES for inhomogeneousturbulence; 6. Current challenges for LES; 7. LES ofcompressible turbulence; 8. Geophysical fluid dynamics.2005/248 pp./48 halftones/70 line diagrams/1 table78124-8/Hb/List: $65.00Disc.: $52.00

The Potential Distribution Theoremand Models of Molecular SolutionsThomas BeckUniversity of Cincinnati, OHMichael PaulaitisJohns Hopkins University, Baltimore, MDLawrence PrattLos Alamos National Laboratory, NM

An understanding of statistical thermodynamicmolecular theory is fundamental to theappreciation of molecular solutions. This complexsubject has been simplified by the authors withdown-to-earth presentations of molecular theory.Using the potential distribution theorem (PDT) asthe basis, the text provides an up-to-date discussionof practical theories in conjunction with simulationresults. The authors discuss the field in a conciseand simple manner, illustrating the text with usefulmodels of solution thermodynamics and numerousexercises. Modern quasi-chemical theories thatpermit statistical thermodynamic properties to bestudied on the basis of electronic structurecalculations are given extended development, as isthe testing of those theoretical results with ab initiomolecular dynamics simulations. The book isintended for students taking up research problemsof molecular science in chemistry, chemicalengineering, biochemistry, pharmaceuticalchemistry, nanotechnology, and biotechnology.

Contents:1. Introduction; 2. Statistical thermodynamic necessities;3. Potential distribution theorem; 4. Models; 5.Generalities; 6. Statistical tentacles; 7. Quasi-chemicaltheory; 8. Developed examples; Index; References.2006/c. 300 pp./97 line diagrams82215-7/Hb/List: $125.00Disc.: $100.00

Simulating Hamiltonian DynamicsB. LeimkuhlerUniversity of Leicester, UKS. ReichImperial College London, UK

The simulation of matter by direct computation ofindividual atomic motions has become animportant element in the design of new drugs andin the construction of new materials. This bookdemonstrates how to implement the numericaltechniques needed for such simulation, therebyaiding the design of new, faster, and more robustsolution schemes. Clear explanations and many

examples and exercises will ensure the value of thistext for students, professionals, and researchers.

Contents:1. Molecular models and simulation; 2. CanonicalHamiltonian systems; 3. Numerical methods; 4.Development of geometric integrators; 5. Multiple timescales in molecular dynamics; 6. Constraints inmolecular dynamics; 7. Properties of geometricintegrators; Bibliography; Index

Cambridge Monographs on Applied and ComputationalMathematics 14

2005/396 pp./30 halftones/80 line diagrams77290-7/Hb/List: $75.00Disc.: $60.00

Liquid Crystalline PolymersSecond EditionAthene Donald University of CambridgeAlan Windle University of CambridgeSimon Hanna University of Bristol

“This book admixes chemistry, physics, and mechanicsat an accessible level. It also presents a lucid, practicalview on potentially useful materials. I find this textrather unique.”

— Pierre-Gilles de Gennes, College de France, Paris, FranceNobel Prize in Physics 1991

“This book has always been THE definitive book onliquid crystalline polymers, tying together synthesis,theory, structure, processing and properties in a most-readable format. I am delighted to see that this newedition contains additional material which iscompletely up-to-date and includes the newest liquidcrystal-forming polymer of all, the carbon nanotube.”

— Richard E. Smalley, Rice University, USA, Nobel Prize inChemistry 1996

The new edition of this authoritative guide onliquid crystalline polymer (LCP) science has beenproduced in response to the wealth of new materialrecently generated in the field. It takes the readerthrough the theoretical underpinnings to real-world applications of LCP technology in a logical,well-integrated manner. A chapter on liquidbiopolymers has been introduced, while the in-depth discussion on applications describes not onlymaturing fields of high-strength structural LCPs,but also a detailed analysis of the developing area offunctional materials. The in-depth coverage anddetailed glossary establishes this as an indispensabletext for graduate students and researchers in thepolymer field, as well as being of interest to thoseworking in chemistry, physics, and materialsscience.

Contents:1. Liquid crystalline polymers: a brief history; 2.Terminology and concepts; 3. Stability of liquidcrystalline polymers; 4. Theories of liquid crystallinity inpolymers; 5. Local order and classification; 6.



Distortions and defects; 7. Biological liquid crystallinepolymers; 8. Flow and applied fields; 9. Processing andapplications of structural liquid crystalline polymers; 10.Applications of functional liquid crystal polymers.2005/c. 600 pp./51 halftones/236 line diagrams58001-3/Hb/List: $90.00Disc.: $72.00

Distillation Theory and ItsApplication to Optimal Design ofSeparation UnitsF.B. PetlyukECT Service, Moscow, Russia

Writing for designers and operators of separationunits in the chemical, pharmaceutical, food, andrelated industries as well as software designers, F.B.Petlyuk presents a clear, multidimensionalgeometric representation of distillation theory validfor all types of distillation column types, splits, andmixtures. DistillDesigner software allowsrefinement and confirmation of the algorithms ofoptimal design. Methods of the general geometrictheory of distillation, encoded in DistillDesigner,provide quick and reliable solutions to problems offlowsheet synthesis and to optimal designcalculations.

Contents:1. Phase equilibrium and its geometrical presentation; 2.Basic concepts of distillation; 3. Trajectories ofdistillation in infinite columns under infinite reflux; 4.Trajectories of thermodynamically reversible distillation;5. Distillation trajectories and conditions of mixturesseparability in simple infinite columns at finite reflux; 6.Distillation trajectories in infinite complex columns andcomplexes; 7. Trajectories of the finite columns and theirdesign calculation; 8. Synthesis of separation flowsheets.

Cambridge Series in Chemical Engineering

2004/360 pp./182 line diagrams/6 tables82092-8/Hb/List: $100.00Disc.: $80.00

Principles of Chemical Separationswith Environmental ApplicationsRichard NobleUniversity of Colorado, BoulderPatricia TerryUniversity of Wisconsin, Green Bay

This introduction to chemical separationstechnology presents the chemical and/or physicalbasis of different techniques and explains how toevaluate them for design and analysis. Chemicalseparations are of central importance in many areasof environmental science, whether it is cleaning uppolluted water or soil, the treatment of dischargestreams from chemical processes, or modificationof a specific process to decrease its environmentalimpact. This textbook is suitable for undergraduateand graduate students taking courses onenvironmental separations or environmentalengineering. Many worked examples and over 100

homework problems are key highlights.

Contents:1. Introduction; 2. Separations as unit operations; 3.Separations analysis fundamentals; 4. Distillation; 5.Extraction; 6. Absorption and stripping; 7. Adsorption;8. Ion exchange; 9. Membranes; Appendices.


2004/336 pp./156 figures/22 tables/115 exercises81152-X/Hb/List: $150.00Disc.: $120.0001014-4/Pb/List: $75.00Disc.: $60.00

Spray SimulationModeling and Numerical Simulation ofSprayforming MetalsUdo FritschingUniversität Bremen, Germany

Spray forming combines the metallurgical processesof metal casting and powder metallurgy to fabricatemetal products with enhanced properties. Thisintroduction to the various modelling andsimulation techniques employed demonstrates howthey are applied in process analysis anddevelopment. Udo Fritsching derives and describesthe main models and then presents theirapplication in the simulation of the key features ofspray forming. Fritsching documents theoreticalresults by referencing them to experimental datawherever possible. The book is aimed at researchersand engineers working in process technology,chemical engineering, and materials science.

Contents:1. Introduction; 2. Spray forming of metals; 3.Modelling of engineering processes; 4. Fluiddisintegration; 5. Spray; 6. Compaction; 7. The coupledapproach; 8. Summary and outlook; Appendices.2004/286 pp./186 figures 13 tables82098-7/Hb/List: $110.00Disc.: $88.00

Basic Concepts for Simple andComplex LiquidsJean-Louis BarratUniversité Claude Bernard Lyon I, Villeurbanne, FranceJean-Pierre HansenUniversity of Cambridge, UK

“A concise, very well-written textbook by two experts inthe field...I enjoyed reading Basic Concepts forSimple and Complex Liquids and have used it in myown research group to introduce students to newresearch areas and ideas. The authors should becommended for an impressive pedagogicalachievement.” —Physics Today

Presenting a unified approach to the liquid state,this book focuses on the concepts and theoreticalmethods necessary for an understanding of thephysics and chemistry of the fluid state. Importantideas are presented in a concise and rigorous style,



and illustrated with examples from both simplemolecular liquids and more complex softcondensed matter systems, such as polymers,colloids, and liquid crystals. After a general chapterintroducing the liquid state, the book is in fourparts devoted to: thermodynamics; structure andfluctuations; phase transitions, interfaces, andinhomogeneous fluids; and, finally, transport anddynamics. Each chapter introduces a new set ofclosely related concepts and theoretical methods,which are then illustrated by a number of specificapplications covering a broad range of physicalsituations.

Contents:1. An introduction to liquid matter; Part I.Thermodynamics, Structure and Fluctuations: 2. Areminder of thermodynamics; 3. Equilibriumfluctuations; Part II. Phase Transitions: 4. Mean fieldapproaches; 5. Critical fluctuations and scaling; Part III.Interfaces and Inhomogeneous Fluids: 6. Macroscopicdescription of interfaces; 7. The density functionalapproach; 8. Curvature and fluctuations; Part IV.Dynamics: 9. Phenomenological description of transportprocesses; 10. Brownian motion, diffusion and theLangevin equation; 11. Response and correlationfunctions; 12. Slow relaxations.2003/308 pp./57 line diagrams/1 table/27 exercises78344-5/Hb/List: $120.00Disc.: $96.0078953-2/Pb/List: $60.00Disc.: $48.00

Computational Models forTurbulent Reacting FlowsRodney FoxIowa State University, Ames

“...I strongly recommend this book, and I feel it wouldmake an excellent addition to any personal or publiclibrary.”

—AIAA Journal

This book presents the current state of the art incomputational models for turbulent reacting flows,and analyzes carefully the strengths and weaknessesof the various techniques described. The focus is onformulation of practical models as opposed tonumerical issues arising from their solution. Atheoretical framework based on the one-point, one-time joint probability density function (PDF) isdeveloped. It is shown that all commonlyemployed models for turbulent reacting flows canbe formulated in terms of the joint PDF of thechemical species and enthalpy. Models based ondirect closures for the chemical source term as wellas transported PDF methods are covered in detail.An introduction to the theory of turbulent andturbulent scalar transport is provided forcompleteness. The book is aimed at chemical,mechanical, and aerospace engineers in academiaand industry, as well as developers ofcomputational fluid dynamics codes for reactingflows.

Contents:1. Turbulent reacting flows; 2. Statistical description ofturbulent flow; 3. Statistical description of turbulentmixing; 4. Models for turbulent transport; 5. Closuresfor the chemical source term; 6. PDF methods forturbulent reacting flows; 7. Full PDF simulations;Appendices


2003/438 pp./91 figures/15 tables65049-6/Hb/List: $140.00Disc.: $112.0065907-8/Pb/List: $70.00Disc.: $56.00

Process ControlA First Course with MATLAB®

Pao C. ChauUniversity of California, San Diego

“This book operates well as a succinct and readableintroductory text for students studying process control,as well as for professionals undertaking industrial shortcourses or looking for a brief reference. It will also serveadmirably as a useful teaching textbook...a book thatinforms, illuminates, and is sure to elicit livelydiscussions from the teacher and the taught in anycourses that utilize it.”

—Current Engineering Practice

An introductory textbook suitable for a two-semester course, Process Control covers the mostessential aspects of process control. While classicaltechniques are discussed, also included is adiscussion of state space modeling and control, amodern control topic lacking in most introductorytexts. MATLAB®, a popular engineering softwarepackage, is employed as a powerful yetapproachable computational tool. Text examplesdemonstrate how root locus, Bode plots, and timedomain simulations can be integrated to tackle acontrol problem. Classical control and state spacedesigns are compared. Each chapter concludes withproblem sets, to which hints or solutions areprovided. A web site provides excellent support inthe way of MATLAB® outputs of text examples andMATLAB® sessions, references, and supplementarynotes. Students and professionals will find it auseful text and reference.

Contents:1. Introduction; 2. Mathematical preliminaries; 3.Dynamic response; 4. State space representation; 5.Analysis of PID control systems; 6. Design and tuning ofsingle-loop control systems; 7. Stability of closed-loopsystems; 8. Frequency response analysis; 9. Design ofstate space systems; 10. Multiloop systems; MATLABtutorial sessions; References; Homework problems


2002/328 pp./127 line diagrams/4 tables80760-3/Hb/List: $130.00Disc.: $104.0000255-9/Pb/List: $55.00Disc.: $44.00



Chemical Product DesignE.L. CusslerUniversity of Minnesota, MinneapolisG.D. MoggridgeUniversity of Cambridge

“Chemical engineering students and beginningchemical engineers will find this text an invitingintroduction to chemical product design. The book isalso well worth the attention of many more than thisaudience. It renders a significant service for those inchemical product design in the chemical industry. Thisis an important book on current concerns, a pleasureand an education to read.”

—Current Engineering Practice

Most chemical companies now devote newresources to the design and manufacture ofspecialty, high-value-added chemical products suchas pharmaceuticals, cosmetics, and electroniccoatings. The training of chemical engineers hasremained static, however, emphasizing traditionalcommodities. This ground breaking text redressesthe balance between commodities and higher-value-added products. It expands the scope ofchemical engineering design to encompass bothprocess design and product design. The authors usea four-step procedure for chemical productdesign—needs, ideas, selection, manufacture—drawing numerous examples from industry toillustrate the discussion. Chemical engineeringstudents and beginning chemical engineers willfind this text an inviting introduction to chemicalproduct design.

Contents:1. An introduction to chemical product design; 2.Needs; 3. Ideas; 4. Selection; 5. Product manufacture; 6.Specialty chemical manufacture; 7. Economic concerns.


2001/248 pp./44 line diagrams79183-9/Hb/List: $100.00Disc.: $80.0079633-4/Pb/List: $39.99Disc.: $31.99

Chemical Engineering Design andAnalysisAn IntroductionT. Michael DuncanCornell UniversityJeffrey A. ReimerUniversity of California, Berkeley

“This innovative text offers a well-paced introductionto chemical engineering. Through a series of real-worldexamples and extensive exercises, students learn thebasic engineering concepts of design and analysis.”

—Engineering Designer

“After discussing what chemical engineering is andwhat chemical engineers do (and get paid for), thebook introduces the concept of design. It then goes on to

cover engineering analysis in a decreasing order of‘exactness’: mathematical modeling based on laws,graphical analysis based on empirical measurements,and dimensional analysis and scaling. I like thisorganization very much because it provides studentswith a perspective of the different ways by whichengineers solve problems...The writing is informal,clear, and easy to follow. Almost all principles andmethods are taught by examples...Principles arebrought in on a just-in-time basis. This style ofpresentation would certainly benefit the learner.”

—Edmund Ko, Carnegie Mellon University

Contents:Preface; 1. An overview of chemical engineering; 2.Process design; 3. Mathematical modeling; 4. Graphicalanalysis; 5. Dimensional analysis and dynamic scaling; 6.Transient systems; Appendices; Glossary; Index.


1998/400 pp./350 line diagrams/14 tables/160 exercises63041-X/Hb/List: $130.00Disc.: $104.0063956-5/Pb/List: $55.00Disc.: $44.00

DiffusionMass Transfer in Fluid SystemsSecond EditionE.L. CusslerUniversity of Minnesota

“Very effective in leading the reader from one level ofsophistication to the next...a wide variety of examplesis presented from areas such as bioengineering, foodscience, and electrochemistry, in addition totraditional areas of chemical engineering....Insummary, this is an outstanding example of a textwritten by an expert in the field.”

—Journal of the American Chemical Society

Contents:1. Models for diffusion; Part I. Fundamentals ofDiffusion: 2. Diffusion in dilute solutions; 3. Diffusionin concentrated solutions; 4. Dispersion; Part II.Diffusion Coefficients: 5. Values of diffusion coefficients;6. Diffusion of interacting species; 7. Multicomponentdiffusion; Part III. Mass Transfer: 8. Fundamentals ofmass transfer; 9. Absorption; 10. Distillation; 11.Extraction; 12. Adsorption; 13. Forced convection; 14.Free convection; Part IV. Diffusion Coupled with OtherProcesses: 15. General questions and heterogeneouschemical reactions: 16. Homogeneous chemicalreactions; 17. Membranes; 18. Controlled release; 19.Heat transfer; 20. Simultaneous heat and mass transfer.


1997/600 pp./1 halftone/206 line diagrams/60 tables/193exercises56477-8/Pb/List: $60.00Disc.: $48.00




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__ 800226 Baldi/DNA ....................Hb $65.00 $52.00

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__ 659078 Fox ............................Pb $70.00 $56.00

__ 820987 Fritsching/Spray............Hb $110.00 $88.00

__ 791650 Haynie/Biological..........Hb $95.00 $76.00

__ 795494 Haynie .........................Pb $45.00 $36.00

__ 846374 Kamm/Models .............Hb $90.00* $72.00*

__ 852889 Kiusalaas/MATLAB® ....Hb $85.00 $68.00

__ 852870 Kiusalaas/Python ..........Hb $85.00 $68.00

__ 846358 Laurendeau/Statistical ..Hb $90.00 $72.00

__ 772907 Leimkuhler/

Hamiltonian..........Hb $75.00 $60.00

__ 781248 Lesieur/Large-Eddy.......Hb $65.00 $52.00

__ 808677 Nicholl/Genetic ............Hb $70.00 $56.00

__ 004713 Nicholl .........................Pb $30.00 $24.00

__ 81152X Noble/Separations........Hb $150.00 $120.00

__ 010144 Noble...........................Pb $75.00 $60.00

__ 582067 O’Connell/

Thermodynamics ..Hb $100.00 $80.00

__ 859034 Palsson/Systems ...........Hb $75.00* $60.00*

__ 839068 Parsegian/

Van der Waals ......Hb $110.00 $88.00

__ 547784 Parsegian .....................Pb $50.00 $40.00

__ 820928 Petlyuk/Theory .............Hb $100.00 $80.00

__ 840317 Ratledge/Basic..............Hb $120.00* $96.00*

__ 549582 Ratledge ......................Pb $60.00 $48.00*

__ 809347 Ringo/Genetics.............Hb $110.00 $88.00

__ 006333 Ringo ...........................Pb $50.00 $40.00

__ 81524X Serdyuk/Methods.........Pb $85.00* $68.00*

__ 833329 Smith/Biotechnology....Hb $80.00 $64.00

__ 540771 Smith ...........................Pb $29.99 $23.99

__ 844193 Sneppen/Physics...........Hb $70.00 $56.00

__ 819822 Stekel/Microarray .........Hb $120.00 $96.00

__ 52587X Stekel...........................Pb $48.00 $38.40

__ 815185 Tavoularis/

Measurement.......Hb $85.00 $68.00

__ 847575 Temkin/Suspension ......Hb $110.00 $88.00

__ 831288 Weinhold/Valency ........Hb $110.00 $88.00

__ 812402 Wilson/Biofilms ............Hb $110.00 $88.00

__ 828899 Wilson/Principles ..........Hb $140.00 $112.00

__ 535816 Wilson .........................Pb $70.00 $56.00

%

All individual orders must be prepaid or charged on American Express, VISA or MasterCard (libraries excepted).Books are only available for shipment within North America. The use of a credit card will expedite your order. It allowsus to process your order more quickly and you are only charged for the book(s) at the time of shipment. Any book(s) not yetpublished, or temporarily out of stock, will be charged only when the book(s) becomes available and is in the process ofbeing shipped. A maximum of 3 copies of any single publication will be supplied per order at the discount prices. Residentsof New York and California, please add appropriate sales tax. Canadian customers: books shipped to Canadianaddresses will be billed in CAD $ (our CAD $ price plus 7% GST). Any special offers included on this form will behonored. We ask that Canadian customers pay with a credit card. Shipping charges in North America are $6.00 forthe first book; $1.75 for each additional book. Includes UPS delivery for most domestic orders. Special subscription discountscannot be applied to previously paid and processed orders. Cambridge ISBN prefix is 0-521. Please allow 3-4 weeks fordelivery. ALL PRICES SUBJECT TO CHANGE. EXPIRATION DATE: JUNE 30, 2006.

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