Edmonton obesity staging system

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Edmonton Obesity Staging System (EOSS) Arya M Sharma, MD, FRCP(C) Professor of Medicine Chair in Obesity Research & Management University of Alberta Edmonton, AB, Canada www.drsharma.ca

description

The Edmonton obesity staging system (EOSS), is a 5-point ordinal classification system that considers comorbidity and functional status, in predicting mortality in a nationally representative US sample. In analysis of three large independent data sets (NHANES, COOPER Study), the Edmonton obesity staging system independently predicted increased mortality even after adjustment for contemporary methods of classifying adiposity. The Edmonton obesity staging system may offer improved clinical utility in assessing obesity-related risk and prioritizing treatment.

Transcript of Edmonton obesity staging system

Page 1: Edmonton obesity staging system

Edmonton Obesity Staging System (EOSS)

Arya M Sharma, MD, FRCP(C)Professor of Medicine

Chair in Obesity Research & ManagementUniversity of Alberta

Edmonton, AB, Canadawww.drsharma.ca

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www.drsharma.ca

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Edmonton Obesity Staging System (EOSS)

Stage 0

Sharma AM & Kushner RF, Int J Obes 2009

Stage 1

Stage 2

Stage 3

Stage 4

Med

ical

Men

tal

Func

tiona

l

abse

nt

abse

nt

abse

nt

pre-

clini

cal

risk

fact

ors

mild

mild

co-morbidity

moderate

moderateend-organ

damage

severesevere

end-stage

end-stage

end-stage

Obesity

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Edmonton Obesity Staging System (EOSS)

Stage 0 Normal blood pressure

Sharma AM & Kushner RF, Int J Obes 2009

Stage 1 Pre-hypertension

Stage 2

Hypertension

Stage 3LVHCHD

Stage 4HeartFailure

Hypertension

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Edmonton Obesity Staging System (EOSS)

Stage 0 Normal blood glucose

Sharma AM & Kushner RF, Int J Obes 2009

Stage 1 IFT/IGT

Stage 2

Type 2Diabetes

Stage 3Micro-/macro-vascular

disease

Stage 4BlindnessESRD

Type 2 Diabetes

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EOSS Predicts Mortality in NHANES III

Padwal R, Sharma AM et al. CMAJ 2011www.drsharma.ca

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EOSS Predicts Mortality at Every Level of BMINHANES III

Padwal R, Sharma AM et al. CMAJ 2011

Overweight

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Association Between EOSS and Mortality Risk in Aerobics Center Longitudinal Study (n = 29 533)

Kuk JL, et al. Appl. Physiol. Nutr. Metab. 2011;36: 570www.drsharma.ca

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EOSS Distribution Across BMI CategoriesNHANES III (1988-1994)

15%

28%

47%

10%

5%

17%

64%

14%

Class II

8%

19%

59%

14%

Class I

5%14%

67%

14% EOSS Stage 0

EOSS Stage 1

EOSS Stage 2

EOSS Stage 3

Overweight

ClassIII

Padwal R, Sharma AM et al. CMAJ 2011

50 million

23 million

10 million

6 million

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EOSS Case 1

24 year-old physically active female, BMI of 32 Kg/m2

no demonstrable risk factors, no functional limitations, or mental health issues

Class I, Stage 0 Obesity

- Focus on prevention of further weight gain- Health benefits of more aggressive obesity

treatment likely marginal

Sharma AM & Kushner RF, Int J Obes 2009www.drsharma.ca

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EOSS Case 2

32 year-old male BMI of 36 Kg/m2

hypertension, sleep apnea, depression

Class 2, Stage 2 Obesity

- Clear benefits of obesity treatment

Sharma AM & Kushner RF, Int J Obes 2009www.drsharma.ca

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EOSS Case 3

63 year-old male BMI of 74 Kg/m2

disabling osteoarthritis (wheel chair)severe hypoventilation, fibromyalgia,

generalized anxiety disorder

Class 3, Stage 4 Obesity

- Aggressive obesity treatment unless deemed palliative

Sharma AM & Kushner RF, Int J Obes 2009www.drsharma.ca

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Key Points

• EOSS provides a rational framework for clinical prioritization and management

• EOSS stage is a better predictor of obesity risk than BMI or waist circumference

• Assessing EOSS stage should be part of the clinical assessment of obesity

• Management strategies should be based on EOSS stage

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