Editorial Advances in Microbial and Nucleic Acids...
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Editorial Advances in Microbial and Nucleic Acids Biotechnology Gamal Enan , 1 Mohamed E. Osman, 2 Mahmoud E. F. Abdel-Haliem, 1 and Salah E. Abdel-Ghany 1,3 1 Department of Botany and Microbiology, Faculty of Science, Zagazig University, Zagazig 44519, Egypt 2 Department of Botany and Microbiology, Helwan University, Cairo, Egypt 3 Department of Biology, Colorado State University, Fort Collins, CO 80523, USA Correspondence should be addressed to Gamal Enan; [email protected] Received 6 May 2018; Accepted 6 May 2018; Published 24 June 2018 Copyright © 2018 Gamal Enan et al. is is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Biotechnology in its broad meaning is the use of organisms or their products for various purposes such as fast diagnosis of infectious diseases, inhibition of the antibiotic resistant bacteria, production of pharmaceuticals, biomaterials, and even energetic materials. Recent challenges in Biotechnology offer state-of-the art studies covering a wide spectrum of biotechnological applications in different organisms for dif- ferent purposes that serve agriculture, environment, health, and industry. Genomes of both eukaryotes and prokaryotes are recently engineered for advances in food safety and development in all fields. e call for submission of manuscripts allowed research- ers in Biotechnology fields to submit their original and novel findings to this special issue. Nineteen manuscripts were submitted. According to precise peer review processes as well as the policies and standards applied in the journal, only seven of them were accepted and they are in the context of this special issue. e full papers in this issue are categorized in four different subjects based on the scope of the Biotechnology applications. ree papers in this special issue discussed results in the immunotherapeutic field. e paper titled “Mannose- Binding Lectin: A Potential erapeutic Candidate against Candida Infection” showed the potential therapeutic capa- bility of mannose binding lectin (MBL) against candidi- asis as this recombinant MBL induced agglutination of both Candida albicans and C. glabrata. In their extended studies in the paper titled “Mannose-Binding Lectin Gene Polymorphism and Its Association with Susceptibility to Recurrent Vulvovaginal Candidiasis,” the authors studied the MBL gene polymorphism and its association with recurrent vulvovaginal candidiasis (RVVC) and found a close corre- lation between innate immunity gene mutation and poly- morphism in MBL gene and the existence of RVVC. ey concluded that MBL genotypic analysis can be used as a surrogate for MBL serum level in order to identify MBL- deficient women for alterative therapeutic options. In the same category, the paper titled “Microcrystalline Cellulose for Delivery of Recombinant Protein-Based Antigen against Erysipelas in Mice” is very interesting as it developed micro- crystalline cellulose for delivery of recombinant protein- based antigen against erysipelas in mice. is recombinant surface protein (SPA) from the Gram positive pathogen Erysipelothrix rhusiopathiae was fused to cellulose binding domain from Trichoderma harzianum (CBD). is CBD-SPA fusion cassette was expressed in E. coli successfully. Molecular cloning and gene expression category include 2 papers. In the paper titled “LraI from Lactococcus raffino- lactis BGTRK10-1, an Isoschizomer of EcoRI, Exhibits Ion Concentration-Dependent Specific Star Activity,” the results obtained found that Lactococcus raffinolactis BG TRK10- 1 produces a novel LraI type II restriction endonuclease which is an isoschizomer of EcoR1, and the gene encoding its production was cloned and expressed successfully in the E. coli bacterium. In the other paper of this category titled “Cloning and Expression of the Organophosphate Pesticide- Degrading - Hydrolase Gene in Plasmid pMK-07 to Confer Cross-Resistance to Antibiotics,” the authors were able to clone and express the --hydrolase gene in some strains of bacteria belonging to the genus Bacillus; this is a promising result since - hydrolase produced by bacteria degrades the organophosphate pesticide pollutants in soil. Hindawi BioMed Research International Volume 2018, Article ID 3102374, 2 pages https://doi.org/10.1155/2018/3102374
Transcript of Editorial Advances in Microbial and Nucleic Acids...
EditorialAdvances in Microbial and Nucleic Acids Biotechnology
Gamal Enan ,1 Mohamed E. Osman,2
Mahmoud E. F. Abdel-Haliem,1 and Salah E. Abdel-Ghany1,3
1Department of Botany and Microbiology, Faculty of Science, Zagazig University, Zagazig 44519, Egypt2Department of Botany and Microbiology, Helwan University, Cairo, Egypt3Department of Biology, Colorado State University, Fort Collins, CO 80523, USA
Correspondence should be addressed to Gamal Enan; [email protected]
Received 6 May 2018; Accepted 6 May 2018; Published 24 June 2018
Copyright © 2018 Gamal Enan et al. This is an open access article distributed under the Creative Commons Attribution License,which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Biotechnology in its broad meaning is the use of organismsor their products for various purposes such as fast diagnosisof infectious diseases, inhibition of the antibiotic resistantbacteria, production of pharmaceuticals, biomaterials, andeven energetic materials. Recent challenges in Biotechnologyoffer state-of-the art studies covering a wide spectrum ofbiotechnological applications in different organisms for dif-ferent purposes that serve agriculture, environment, health,and industry. Genomes of both eukaryotes and prokaryotesare recently engineered for advances in food safety anddevelopment in all fields.
The call for submission of manuscripts allowed research-ers in Biotechnology fields to submit their original and novelfindings to this special issue. Nineteen manuscripts weresubmitted. According to precise peer review processes aswell as the policies and standards applied in the journal,only seven of them were accepted and they are in thecontext of this special issue. The full papers in this issue arecategorized in four different subjects based on the scope ofthe Biotechnology applications.
Three papers in this special issue discussed results inthe immunotherapeutic field. The paper titled “Mannose-Binding Lectin: A Potential Therapeutic Candidate againstCandida Infection” showed the potential therapeutic capa-bility of mannose binding lectin (MBL) against candidi-asis as this recombinant MBL induced agglutination ofboth Candida albicans and C. glabrata. In their extendedstudies in the paper titled “Mannose-Binding Lectin GenePolymorphism and Its Association with Susceptibility toRecurrent Vulvovaginal Candidiasis,” the authors studied theMBL gene polymorphism and its association with recurrent
vulvovaginal candidiasis (RVVC) and found a close corre-lation between innate immunity gene mutation and poly-morphism in MBL gene and the existence of RVVC. Theyconcluded that MBL genotypic analysis can be used as asurrogate for MBL serum level in order to identify MBL-deficient women for alterative therapeutic options. In thesame category, the paper titled “Microcrystalline Cellulosefor Delivery of Recombinant Protein-Based Antigen againstErysipelas in Mice” is very interesting as it developed micro-crystalline cellulose for delivery of recombinant protein-based antigen against erysipelas in mice. This recombinantsurface protein (SPA) from the Gram positive pathogenErysipelothrix rhusiopathiae was fused to cellulose bindingdomain fromTrichoderma harzianum (CBD).This CBD-SPAfusion cassette was expressed in E. coli successfully.
Molecular cloning and gene expression category include2 papers. In the paper titled “LraI from Lactococcus raffino-lactis BGTRK10-1, an Isoschizomer of EcoRI, Exhibits IonConcentration-Dependent Specific Star Activity,” the resultsobtained found that Lactococcus raffinolactis BG TRK10-1 produces a novel LraI type II restriction endonucleasewhich is an isoschizomer of EcoR1, and the gene encodingits production was cloned and expressed successfully in theE. coli bacterium. In the other paper of this category titled“Cloning and Expression of the Organophosphate Pesticide-Degrading 𝛼-𝛽 Hydrolase Gene in Plasmid pMK-07 toConfer Cross-Resistance to Antibiotics,” the authors wereable to clone and express the 𝛼-𝛽-hydrolase gene in somestrains of bacteria belonging to the genus Bacillus; this is apromising result since 𝛼-𝛽 hydrolase produced by bacteriadegrades the organophosphate pesticide pollutants in soil.
HindawiBioMed Research InternationalVolume 2018, Article ID 3102374, 2 pageshttps://doi.org/10.1155/2018/3102374
2 BioMed Research International
Food Biotechnology area of research includes one paperonly titled “Genetic Analysis with Random Amplified Poly-morphic DNA of the Multiple Enterocin-Producing Entero-coccus lactis 4CP3 Strain and Its Efficient Role on the Growthof Listeria monocytogenes in Raw Beef Meat”; the resultsobtained showed that the Enterococcus lactis 4CP3 straincould be used as meat protective against listerias growth atrefrigeration temperatures. The intraspecific genetic analysisof the 4CP3 strain was assessed by random amplified poly-morphic DNA polymerase chain reaction analysis.
Tissue culture Biotechnology includes one paper titled“Manipulation of Plant Growth Regulators on Phytochem-ical Constituents and DNA Protection Potential of theMedicinal Plant Arnebia benthamii” which showed a novelprotocol for the in vitro regeneration of the medicinalplant Arnebia benthamii by tissue culture techniques. It wasfound that the regenerated plants possessed high content ofvolatile/nonvolatile compounds that showedDNAprotectionpotential against oxidants.
Gamal EnanMohamed E. Osman
Mahmoud E. F. Abdel-HaliemSalah E. Abdel-Ghany
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