Response to: Comment on Prevalence and Risk Factors for ......World Journal Volume 2018 Immunology...
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Letter to the Editor Response to: Comment on “Prevalence and Risk Factors for Diabetic Lower Limb Amputation: A Clinic-Based Case Control Study” Beverly T. Rodrigues , Venkat N. Vangaveti, and Usman H. Malabu Department of Diabetes and Endocrinology, The Townsville Hospital and College of Medicine and Dentistry, James Cook University, 100 Angus Smith Drive, Douglas, QLD 4814, Australia Correspondence should be addressed to Usman H. Malabu; [email protected] Received 5 December 2017; Accepted 19 December 2017; Published 20 February 2018 Academic Editor: Kim Connelly Copyright © 2018 Beverly T. Rodrigues et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The observations by Bakhtiyari and Mansournia on our study [1] were received with great interest. We believe our study was consistent with a case-control format [2]. In partic- ular, our target population was selected from subjects diag- nosed with diabetic foot ulcer (DFU) at the local high-risk foot clinic, effectively fulfilling the criteria of control (DFU without amputations) and case (DFU with amputation), as previously described [3]. The identified risk factors were computed amongst those with and without limb amputa- tions. We do not believe our study was cross-sectional, being retrospective in design, and it was not conducted at a specific point in time rather for a period from January 2011 to December 2013; both are in agreement with the definition of a case-control study [4]. The prevalence of diabetic limb amputation quoted in our study was for our high-risk dia- betic foot clinic and not for the general population of North Eastern Australia which was clearly outlined in the title as clinic-based [5]. Interestingly, in line with Bakhtiyari’s and Mansournia’s observation of a case-control study, our sam- pling was based on the outcome (amputation) and was known in advance prior to conducting the study [3]. Furthermore, in keeping with a case-control study, we did not undertake propensity matching since cases and controls were outcomes rather than exposures [4]. With respect to our discussion on the prevalence of diabetic limb amputation, comparing clinic-based and non-clinic-based studies, the point was noted but we clearly stated our study was similar to those reported by others [6]. Overall, we do not think the title of our article was confusing since it tallied with the methodology and content of the article. Conflicts of Interest The authors declare that they have no conflicts of interest. References [1] M. Bakhtiyari and M. A. Mansournia, “Comment on “Preva- lence and risk factors for diabetic lower limb amputation: a clinic-based case control study”,” Journal of Diabetes Research, vol. 2017, Article ID 6015326, 1 pages, 2017. [2] B. T. Rodrigues, V. N. Vangaveti, and U. H. Malabu, “Preva- lence and risk factors for diabetic lower limb amputation: a clinic-based case control study,” Journal of Diabetes Research, vol. 2016, Article ID 5941957, 7 pages, 2016. [3] P. Büttner and R. Muller, Epidemiology, Oxford University Press, 2015. [4] S. Lewallen and P. Courtright, “Epidemiology in practice: case-control studies,” Community Eye Health, vol. 11, no. 28, pp. 57-58, 1998. Hindawi Journal of Diabetes Research Volume 2018, Article ID 1908140, 2 pages https://doi.org/10.1155/2018/1908140
Transcript of Response to: Comment on Prevalence and Risk Factors for ......World Journal Volume 2018 Immunology...
Letter to the EditorResponse to: Comment on “Prevalence and RiskFactors for Diabetic Lower Limb Amputation: A Clinic-BasedCase Control Study”
Beverly T. Rodrigues , Venkat N. Vangaveti, and Usman H. Malabu
Department of Diabetes and Endocrinology, The Townsville Hospital and College of Medicine and Dentistry, James Cook University,100 Angus Smith Drive, Douglas, QLD 4814, Australia
Correspondence should be addressed to Usman H. Malabu; [email protected]
Received 5 December 2017; Accepted 19 December 2017; Published 20 February 2018
Academic Editor: Kim Connelly
Copyright © 2018 Beverly T. Rodrigues et al. This is an open access article distributed under the Creative Commons AttributionLicense, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work isproperly cited.
The observations by Bakhtiyari and Mansournia on ourstudy [1] were received with great interest. We believe ourstudy was consistent with a case-control format [2]. In partic-ular, our target population was selected from subjects diag-nosed with diabetic foot ulcer (DFU) at the local high-riskfoot clinic, effectively fulfilling the criteria of control (DFUwithout amputations) and case (DFU with amputation), aspreviously described [3]. The identified risk factors werecomputed amongst those with and without limb amputa-tions. We do not believe our study was cross-sectional, beingretrospective in design, and it was not conducted at a specificpoint in time rather for a period from January 2011 toDecember 2013; both are in agreement with the definitionof a case-control study [4]. The prevalence of diabetic limbamputation quoted in our study was for our high-risk dia-betic foot clinic and not for the general population of NorthEastern Australia which was clearly outlined in the title asclinic-based [5]. Interestingly, in line with Bakhtiyari’s andMansournia’s observation of a case-control study, our sam-pling was based on the outcome (amputation) and was knownin advance prior to conducting the study [3]. Furthermore, inkeeping with a case-control study, we did not undertakepropensity matching since cases and controls were outcomesrather than exposures [4]. With respect to our discussion onthe prevalence of diabetic limb amputation, comparing
clinic-based and non-clinic-based studies, the point was notedbut we clearly stated our study was similar to those reported byothers [6]. Overall, we do not think the title of our article wasconfusing since it tallied with the methodology and content ofthe article.
Conflicts of Interest
The authors declare that they have no conflicts of interest.
References
[1] M. Bakhtiyari and M. A. Mansournia, “Comment on “Preva-lence and risk factors for diabetic lower limb amputation: aclinic-based case control study”,” Journal of Diabetes Research,vol. 2017, Article ID 6015326, 1 pages, 2017.
[2] B. T. Rodrigues, V. N. Vangaveti, and U. H. Malabu, “Preva-lence and risk factors for diabetic lower limb amputation: aclinic-based case control study,” Journal of Diabetes Research,vol. 2016, Article ID 5941957, 7 pages, 2016.
[3] P. Büttner and R. Muller, Epidemiology, Oxford UniversityPress, 2015.
[4] S. Lewallen and P. Courtright, “Epidemiology in practice:case-control studies,” Community Eye Health, vol. 11, no. 28,pp. 57-58, 1998.
HindawiJournal of Diabetes ResearchVolume 2018, Article ID 1908140, 2 pageshttps://doi.org/10.1155/2018/1908140
[5] C. T. Le and J. R. Boen,Health and Numbers: Basic BiostatisticalMethods, John Wiley, Chichester, 1995.
[6] W. Amogne, A. Reja, and A. Amare, “Diabetic foot disease inEthiopian patients: a hospital based study,” Ethiopian Journalof Health Development, vol. 25, no. 1, pp. 17–21, 2011.
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