DRUGS NAME THERAPUETIC ACTIONS

INDICATIONS CONTRAINDICATIONS ADVERSE EFFECTS

NURSING CONSIDERATIONS

1. Iterax T tsp ID

GENERIC NAME:

>Hydroxyzine

DRUG CLASS:

>antianxiety agents >antihistamines >sedative

> competes with histamine for H1-receptor sites on effector cells in the GIT, blood vessels, and respiratory tract

>Treatment of anxiety, preoperative sedation, antiemetic, antipuritic, may becombined with opioid anagesics

> hypersensitivity,

pregnancy

INTERACTIONS:

> CNS depressants eg narcotics, non-narcotic analgesics, barbiturates & alcohol. Phenytoin, epinephrine.

> CNS: drowsiness, agitation, ataxia, dizziness, headache, weakness Resp:wheezing >GI: dry mouth, bitter taste, constipation, nausea >Derm: Flushing>Others : pain and abscesses at IM site, chest tightness, urinary retention

>Assess client for

dizziness and

drowsiness

>Assess client with

kidney disease

>Assess clients for

allergic reactions

2. Amoxiclar syrup 3.75 l BID

> Inhibits enzymes involved in formation of peptidoglycan layer of bacterial cell wallNo effect on human cell wallsBactericidal; only works on

> Infections due to ß-lactamase-resistant infections where amoxycillin alone is inappropriate - e.g. staphs, E. coli strains, H. influenzae strainsBacteroides and Klebsiella speciesRespitratory tract

> Penicillin hypersensitivity> History of co-amoxiclav-associated or penicillin-associated jaundice or hepatic dysfunction

> Hepatitis, cholestatic jaundiceErythema multiforme (including Stevens-Johnson)Toxic epidermal necrolysis; exfoliative

> Assess bowel pattern before and during treatment as pseudomembranous colitis may occur.

> Report haematuria or oliguria as high doses can be

dividing bacteriaWell absorbed enterallyClavulanic acid inhibits bacterial ß-lactamase

infectionsGenito-urinary infectionsAbdominal infectionsCellulitisAnimal bites

dermatitis>Diarrhea, vomitingRashesNeutropeniaAnaemia

nephrotoxic.

> Assess respiratory status.

> Observe for anaphylaxis.

> Ensure that the patient has adequate fluid intake during any diarrhoea attack.

> Patient teaching> If the patient develops a rash, wheezing, itching, fever or swelling in the joints, this could indicate an allergy and should be reported.

> Patients must ensure they take the full course of the medicine.

> The medicine must be taken in equal doses around the clock to maintain level in

the blood.

> If oral contraceptives are used, use alternative contraception.

> Report diarrhoea, cramping and blood in stools as pseudomembranous colitis may occur.

3. Paracetamol 200 ml every 4 hour for temp. 37.8 degree celius.

GENERIC NAME

>Acetaminophen

>Decrease fever by inhibiting the effects of pyrogens on the hypothalamic heat regulating centers and by a hypothalamic action leading to sweating and vasodilatation.>Relieves pain by inhibiting prostaglandin synthesis at the CNS but does not haves anti-

>Relief of mild to moderate pain, treatment of fever

>Hypersensitivity, intolerance to tartrazine (yellow dye number 5)’, alcohol, table sugar, saccharin.

DRUG INTERACTION:

>Drug-Drug - Barbiturates, Carbamazepine,

Hydantoins, Rifampin, Sulfinpyrazone: high doses or long-term use of these drugs may reduce therapeutic effects and

>Stimulation, drowsiness, nausea, vomiting, abdominal pain, hepatoxicity, hepatic seizure, (overdose), renal failure, (high prolonged doses), leucopenia, neutropenia, hemolytic anemia,(long term use), thrombocytopenia, pancytopenia, CNS stimulation, delirium followed

>Tell patient to read label on other OTC drugs. Advice patient to avoid taking more than one product containing paracetamol (acetaminophen) at one time, as this ay cause toxicity if taken concurrently.>Advise patient to avoid alcohol, acute poisoning with liver damage may result, acute toxicity includes symptoms of nausea,

inflammatory action because of its minimal effect of peripheral prostaglandin synthesis.

enhance hepatotoxic effects of acetaminophen. Avoid using together. - Lamotrigine: may decrease lamotrigine level. Monitor patient for therapeutic effects. - Warfarin: may increase hypoprothrombinemic effects with long-term use with high doses of acetaminophen. Monitor INR closely. - Zidovudine: may decrease zidovudine effects. Monitor patient closely. Drug-Herd - Watercress: may inhibit oxidative metabolism of acetaminophen. Discourage use together. Drug-Food - Caffeine: may enhance analgesic effects of acetaminophen. Products may combine caffeine and acetaminophen for therapeutic advantage.

by vascular collapse, convulsion, coma, death

vomiting, and abdominal pain, and physician should be notified immediately.> Teach patient to recognize signs of chronic overdose, bleeding, bruising, malaise, fever, sore throat>Inform patient that urine may become dark brown as a result of phenacetin ( metabolite of acetaminophen)>Tell patient notify prescribe for pain or fever lasting for more than 3 days.

>Drug-Lifestyle - Alcohol use: may increase risk of hepatic damage. Discourage use together.

4. Vitamin K 5mg ID x 2 days

>Required for hepatic synthesis of blood coagulation

> Anticogulant- induced prothrombin deficiency caused by coumarin or inanedione derivatives> Prophylaxis and therapy of hemorrhagic disease of the newborn>Hypoprothrombinemia secondary to factors liiting absorption or synthesis of vitamin K, e.g obstructive jaundice, biliary fistula, sprue, ulcerative coilitis, celiac disease, intestinal resection, cystic fibrosis of the pancreas, and regional enteritis.>Other drug hypoprothrobineia.

> Hypersensitivity to any component of this medication.

>Transient “flushing sensations of taste have been observed, as well as rare instances of dizziness, rapid and weak pulse, profuse sweating, brief hypotension, dysnea, and cyanosis> Pain swelling and tenderness at the injection site may occur.> The possibility of allergic sensitivity including an anaphylactoid reaction should be kept on mind.> Infrequently, usually after repeated injection,

>Monitor for frank and occult bleeding (guaiac stools, hematest urine, and emesis). > onitor pulse and blood pressue frequent.y, notify physician immediately if symptoms of internal bleeding or hypovolemic shock develop.> Inform all personnel of patient’s bleeding tendency to prevent further trauma. > Apply pressure to all venipuncture sites for atleast 5 min, avoid unnecessary IM injection.

erythematous, indurated, pruritic plaques have occurred, rarely, these have progressed to scleroderma like lesions that have persisted for long periods. In other cases, these lesions have resembled erythema perstans.

5. Herax t tsp ID >stimulates

natural healing powers, strengthening

>Treatment of herpes simplex & varicella-zoster infections.>healing of cold sores,

> Hypersensitivity. Patients w/ adnormally low neutrophil counts (< 0.75 x 10x9/L), or

>Transient increase in urine and serum uric acid level; very

>Monitor increase in serum uric acid level, gout, urolithiasis or renal dysfunction;

immune system so that outbreaks heal faster or simply don’t occur at all.

>Non-toxic immune system stimulant.

DRUG CLASS

> Antiviral

fever blisters>

abnormally low haemoglobin levels (< 7.5 g/dL or 4.65 mmol/L)

rarely skin rashes; pruritis; GI upset; nausea; fatigue; malaise

pregnancy and lactation >Monitor hematological parameters

PATIENT TEACHING:

PatieP>Inform patient that the drug must be taiken 1 hour apart on an empty Stomach>Instruct the patient to notify prescriber if unusual effects occurs