Drug Testing in the Drug Testing in the U.S. Racing IndustryU.S. Racing Industry

Scot Waterman, DVMScot Waterman, DVM

Executive DirectorExecutive Director

RMTCRMTC

Drug Testing StatisticsDrug Testing Statistics

Results from two surveys sent in Results from two surveys sent in 2001 by the NTRA and 2008 by 2001 by the NTRA and 2008 by the RMTCthe RMTC

Surveys were substantially Surveys were substantially similar and very detailedsimilar and very detailed

Able to draw conclusions as to Able to draw conclusions as to how drug testing is changinghow drug testing is changing

Some statistics will be presented Some statistics will be presented without identifying jurisdictionwithout identifying jurisdiction

Animal Selection for Animal Selection for TestingTesting

““Top 12”Top 12” Avg Tested Avg Tested

Per CardPer CardAvg Avg

Tested Tested

Per RacePer Race#1#1 36 (TB) 33 (H)36 (TB) 33 (H) 4.0(TB) 3.0 (H)4.0(TB) 3.0 (H)

#2#2 2424 2.02.0

#3#3 2323 2.42.4

#4#4 2222 2.22.2

#5#5 2020 2.02.0

Total Spent AnnuallyTotal Spent Annuallyon Lab Services on Lab Services

(2007)(2007)““Haves”Haves” ““Have Nots”Have Nots”

#1 $4.0 million#1 $4.0 million #38 $10,000#38 $10,000

#2 $3.4 million#2 $3.4 million #37 $15,000#37 $15,000

#3 $3.4 million#3 $3.4 million #36 $26,000#36 $26,000

#4 $2.0 million#4 $2.0 million #35 $50,000#35 $50,000

#5 $1.7 million#5 $1.7 million #34 $52,000#34 $52,000

Treatment of Treatment of Laboratory FeesLaboratory Fees

0

20

40

60

80

100

120

140

160

180

Blo

od &

Uri

ne S

am

ple

Cost

A B C D E F G H I J K L M N O P Q R S

State

Sample CollectionSample CollectionMedium of ChoiceMedium of Choice

020000400006000080000

100000120000140000160000180000

1999 2006

UrineBlood

Urine Screening Urine Screening TechniquesTechniques

2001 vs. 20072001 vs. 2007MethodologyMethodology Number of Number of

States States Utilizing—Utilizing—

20012001

Number of Number of States States

Utilizing—Utilizing—2007 2007

Thin Layer Thin Layer ChromatograChromatogra

phyphy

28/30 (93%)28/30 (93%) 19/28 19/28 (63%)(63%)

ELISAELISA 30/30 (100%)30/30 (100%) 18/18 (100%)18/18 (100%)

HPLCHPLC 11/30 (37%)11/30 (37%) 22/27 22/27 (84%)(84%)

GC/MSGC/MS 11/30 (37%)11/30 (37%) 16/27 16/27 (59%)(59%)

LC/MSLC/MS 5/30 (17%)5/30 (17%) 12/25 12/25 (48%)(48%)

Number of ELISA by Number of ELISA by StateState

0

10

20

30

40

50

60

State

Num

ber o

f ELI

SA

2001

2007

MS Equipment MS Equipment

Cross-Section SampleCross-Section SampleLab/Lab/JurisdictionJurisdiction

# LC/MS# LC/MS # GC/MS# GC/MS

CaliforniaCalifornia 1010 66

PennsylvaniaPennsylvania 88 11

FloridaFlorida 33 22

OhioOhio 22 22

IllinoisIllinois 11 44

New JerseyNew Jersey 11 44

MassachusettsMassachusetts 00 11

MaineMaine 00 33

Jurisdictions Utilizing Jurisdictions Utilizing Accredited Labs in 2007Accredited Labs in 2007

JurisdictionJurisdiction Accrediting Agency & Accrediting Agency & StandardsStandards

ArkansasArkansas A2LA, ISO 17025 (Industrial)A2LA, ISO 17025 (Industrial)

ArizonaArizona A2LA, ISO 17025 (Industrial)A2LA, ISO 17025 (Industrial)

CaliforniaCalifornia A2LA, ISO 17025 (UC-Davis)A2LA, ISO 17025 (UC-Davis)

ColoradoColorado A2LA, ISO 17025 (Industrial)A2LA, ISO 17025 (Industrial)

FloridaFlorida NSFTC, ISO 17025 (Univ. of NSFTC, ISO 17025 (Univ. of FL)FL)

KansasKansas A2LA, ISO 17025 (CFTS)A2LA, ISO 17025 (CFTS)

North DakotaNorth Dakota A2LA, ISO 17025 (Industrial)A2LA, ISO 17025 (Industrial)

PennsylvaniaPennsylvania A2LA, ISO 17025 (Univ. of A2LA, ISO 17025 (Univ. of PA)PA)

South DakotaSouth Dakota A2LA, ISO 17025 (CFTS)A2LA, ISO 17025 (CFTS)

Aggregate StatisticsAggregate Statistics

2001 Total2001 Total 2001 into 2001 into 2007 2007

dollars dollars (inflation (inflation adjusted)adjusted)

2007 Total2007 Total

Total Approx Total Approx Annual Annual Testing Testing

SpendingSpending

(Responding (Responding Jurisdiction)Jurisdiction)

$24 $24 millionmillion

$28,185,3$28,185,33636

$28 $28 millionmillion

Average Spend Average Spend per Responding per Responding

JurisdictionJurisdiction

$814,000$814,000 $955,953$955,953 $836,000$836,000

RMTCRMTCDrug Testing Drug Testing InitiativesInitiatives Post-race testing in the United Post-race testing in the United

States:States:– Currently 18 laboratories conducting Currently 18 laboratories conducting

testing in US…too many labs chasing too testing in US…too many labs chasing too few dollarsfew dollars

– Only 5 labs ISO 17025 accreditedOnly 5 labs ISO 17025 accredited– Funding is state-by-state and many times Funding is state-by-state and many times

is under state procurement laws which is under state procurement laws which reward low bidder or is statutorily reward low bidder or is statutorily directeddirected

– No industry standards for US testing labsNo industry standards for US testing labs

RMTCRMTCDrug Testing Drug Testing InitiativesInitiatives1.1. Creation of Industry Standards for Labs:Creation of Industry Standards for Labs:

– Starting point is Lab Standards document Starting point is Lab Standards document created by the World Anti-Doping Associationcreated by the World Anti-Doping Association

– WADA labs must be ISO 17025 accreditedWADA labs must be ISO 17025 accredited– WADA conducts an external proficiency WADA conducts an external proficiency

program with severe consequences for program with severe consequences for failurefailure

– WADA mandates that laboratories spend a WADA mandates that laboratories spend a percentage of their annual budget on percentage of their annual budget on researchresearch

– WADA stick…Olympic Games, Horse Racing WADA stick…Olympic Games, Horse Racing stick…????? Funding also a key issuestick…????? Funding also a key issue

RMTCRMTCDrug Testing Drug Testing InitiativesInitiatives2.2. Post-doctoral and graduate student Post-doctoral and graduate student

recruitment:recruitment:– Our Laboratory Directors are aging…who Our Laboratory Directors are aging…who

replaces them?replaces them?– Those with research programs that are Those with research programs that are

racing related could do more with racing related could do more with capable studentscapable students

– Developing a comprehensive program to Developing a comprehensive program to target individuals with target individuals with pharmacology/veterinary backgrounds to pharmacology/veterinary backgrounds to place in research positions and will also place in research positions and will also utilize racing laboratories and possibly utilize racing laboratories and possibly U of A RTIP for broad racing educationU of A RTIP for broad racing education

– Initial cost $100,000-200,000Initial cost $100,000-200,000

RMTCRMTCDrug Testing Drug Testing InitiativesInitiatives3.3. Business Plan for US Drug Business Plan for US Drug

Testing Infrastructure:Testing Infrastructure:– What is the most efficient system?What is the most efficient system?– The Jockey Club has been tasked The Jockey Club has been tasked

with this projectwith this project

4.4. Sample Collection and Frozen Sample Collection and Frozen Sample StrategiesSample Strategies– Going back to McKinsey report on Going back to McKinsey report on

sample collectionsample collection– Frozen sample program underwayFrozen sample program underway

RMTCRMTCDrug Testing Drug Testing InitiativesInitiatives Pleased with progress in a short Pleased with progress in a short

periodperiod Will need broad industry Will need broad industry

support to implementsupport to implement– Incremental funding will be neededIncremental funding will be needed– Industry needs to support Industry needs to support

commissions at legislative levelcommissions at legislative level Will need industry organizations Will need industry organizations

with sticks to use themwith sticks to use them

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