Doctoral students in the limelight at the 2nd Erlanger ...
Transcript of Doctoral students in the limelight at the 2nd Erlanger ...
Doctoral students in the limelight at the 2nd Erlanger International ImmunologySymposium
Max Cooper, Klaus Rajewsky, and Kathryn
Calame, in addition to 17 other outstand-
ing scientists in the field of B- and T-cell
immunology, met in October for 3 days at
a scientific tryst in Erlangen. The occasion
was the 2nd International Symposium on
Regulators of Adaptive Immunity, orga-
nized by Erlanger doctoral students work-
ing in the field of immunology.
This symposium, which took place for
the second time in Erlangen, was created
2 years ago with the aim of offering young
scientists the possibility of building inter-
national contacts at the beginning of
their careers and providing a venue for
discussing their research results with
experts in the field. More than 400
students and scientists from Germany and
neighboring countries enrolled in this
year’s meeting and enjoyed the extensive
social program offered at the symposium
in addition to the exciting talks from 20
internationally renowned immunologists
from the United States, Japan, Great
Britain, Portugal, and Germany in the
field of adaptive immunity.
The 20 speakers at this year’s sympo-
sium, which included six members of the
world-renowned National Academy of
Sciences (USA), covered the entire field of
humoral and cellular adaptive immunity,
with an emphasis on the biology of B and
T lymphocytes (Fig. 1). Max Cooper gave
an exciting talk about a new class of
antibody-like antigen receptors in lower
vertebrates. Kathryn Calame (Fig. 2),
Klaus Rajewsky, Michael Neuberger and
Rudolf Grosschedl discussed the roles
of the DNA-modifying activation-induced
cytidine deamidase, the small non-coding
RNA molecules (so-called microRNA) and
other regulators such as transcription
factors during the control of the humoral
immunity. Flavius Martin, Matthias Wabl,
Shigekazu Nagata (Fig. 3), David Nema-
zee, and Mark Shlomchik presented new
perspectives on the elucidation and treat-
ment of autoimmune diseases. Jurgen
Wienands described a novel signaling
pathway that distinguishes naive from
memory B lymphocytes, while Jing Wang,
from the laboratory of Fred Alt, offered
stimulating insights into new molecular
mechanisms for the pathogenesis of
leukemia. In addition, Harald von Boeh-
mer, Dan Littman, Thomas Hunig, Art
Weiss, John Kappler, Antonio Coutinho
(Fig. 4), Georg Bornkamm, and Ulrich
Koszinowski presented new findings
regarding the function of T lymphocytes
during the cellular defense against
tumors, viruses and bacteria as well as
their involvement in autoimmune disea-
ses. The scientific presentations at this
year’s symposium proposed many new
findings in this challenging branch of
immunology and demonstrated the enor-
mous possibilities for translating these
results into new treatment concepts
that may potentially be implemented in
the clinic.
The 42 doctoral students who organized
this symposium are members of training
programs from three specific immunologi-
cally oriented research groups, all of
which are financed by the German
Research Foundation (Deutsche Forschungs-
gemeinschaft, DFG) and include the Research
Training Group (Graduiertenkolleg GK592)
‘Lymphocytes’ (speaker: Hans-Martin Jack)
Figure 1. Guest speakers and congress organizers.
& 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim www.eji-journal.eu
Eur. J. Immunol. 2009. 39: 339–341 FORUM 339
and the Research Group FOR832 ‘Regu-
lators of Humoral Immunity’ (speakers:
Thomas Winkler and Hans-Martin Jack).
Both these groups focus on the differ-
entiation, activation, and deviation of
lymphocytes, whereas the third group,
Training Group GK1071 (speaker: Bern-
hard Fleckenstein), studies the interaction
between viruses and the immune system.
Interestingly, all three programs empha-
size the importance of educating the
public, as evidenced by the fact that the
graduate students participate in the Long
Night of Science in Erlangen and organize
events for the yearly International Day
of Immunology at the market square of
Erlangen. These events, among others,
provide a unique opportunity for the
doctoral students to communicate infor-
mation from various fields of biomedical
sciences such as immunology and infec-
tion biology to the public. Furthermore,
the doctoral students, who serve as
mentors of young pupils from several
Erlanger high schools, also organize
laboratory courses and seminars to further
educate these students.
The idea of organizing an international
congress with a focus on the adaptive
immune system was developed during a
field trip to a Munich biotech company in
December 2005 and subsequently resulted
in the 1st Symposium in September 2006.
Due to the success of this first meeting, the
following class of graduate students deci-
ded to organize the 2nd International
Symposium on Regulators of Adaptive
Immunity. One year in advance, an orga-
nization committee composed of ten
students and two professor-level consul-
tants (Prof. Jack (GK592) and Dr.
Biesinger-Zwostra (GK1071)) began orga-
nizing and developing the curriculum for
this 2nd Symposium. The tasks of the
organizing committee included, among
others, the development of the program,
the generation of a list of invited speakers,
the organization of the social program, and
the pick-up service and hotel reservations
for the guests. In addition, the low regis-
tration fee, which emphasizes the student-
oriented approach of the symposium,
required that the committee procure addi-
tional funds. The student committee was
able to obtain public funding from the Free
State of Bavaria, the German Research
Society, and the Multidisciplinary Centre of
Erlangen for the Clinical Research (IZKF).
Moreover, company contacts established
by a former graduate student during the
organization of the 1st Symposium were
very helpful in collecting generous contri-
butions from a variety of companies.
The selection of the speakers was of
course a high priority; so a ‘‘wish list’’ was
compiled by all the doctoral students
according to their primary research inter-
ests. From this list, the students invited 30
scientists, 20 of whom accepted within a
short period of time. Interestingly, since all
of the speakers are working in the field of
adaptive immunity, most of these partici-
pants knew each other from previous
congresses and thus used the symposium
to exchange ideas with old friends in
addition to building new contacts. As all
the invited speakers communicated to the
students, the most compelling reason for
accepting the invitation was the fact that
Figure 2. Kathryn Calame (New York, USA) talks to a packed lecture hall.
Figure 3. Shigekazu Nagata (Osaka, Japan). Figure 4. Antonio Coutinho (Lisboa, Portugal).
Eur. J. Immunol. 2009. 39: 339–341FORUM340
& 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim www.eji-journal.eu
the symposium was exclusively organized
by graduate students and that the venue of
the congress provided them with the
opportunity to exchange ideas with
colleagues in their field.
However, during the symposium, the
students did not operate simply as organi-
zers; rather, they acted like gracious hosts.
In order to establish a more personable
setting from the beginning, all of the
speakers were met by students at the
airport or at the railway station and were
subsequently accompanied through Erlan-
gen to all of the events. A special session
offering the opportunity to establish
contacts among students and the Erlanger
immunology faculty included a five-course
dinner held on the opening night at a first-
class restaurant in Erlangen. In order to
create a pleasant atmosphere for socializ-
ing, significant importance was placed on
the seating arrangements, such that two
students were located directly next to the
guest speaker of their choice (Fig. 5).
After a very stimulating second day,
the visiting speakers took part in a poster
session organized for the evening by the
Erlanger students. Although there was
initial skepticism from certain guest
speakers regarding the 2 h poster session,
which was open only to the guest speak-
ers, the Erlanger immunology faculty, and
the graduate students, this session proved
to be quite fruitful for everyone. Each
guest speaker found the timeframe and
the limited number of posters to be an
agreeable format and thoroughly enjoyed
the stimulating discussions with the
graduate students as well as the opportu-
nity to develop personal contacts. In
addition, all of the Erlanger graduate
students unanimously concluded that this
was the best and most productive poster
discussion that they ever had.
After intensive exchange of ideas,
everybody was happy to relax in a more
casual atmosphere, for which the official
congress prepared a party for all of
the symposium’s registered participants.
Music was mixed together by an Erlanger
professor for over 250 guests, who cele-
brated into the early morning hours on
the dance floor. Despite a short night of
rest, it was a pleasant surprise to see that
the lecture hall on the following morning
of the last day of the congress was full,
which we believe speaks to the stimulating
nature of the presentations. The congress
finished with a final dinner with an
exciting round of guests and the Erlanger
students and faculty.
In summary, the 2nd International
Symposium on Regulators of Adaptive
Immunity was a great success and would
have not been possible without the
incredible effort from all the graduate
students in addition to the support and
the experience of the faculty members
from the three Erlanger research groups.
This symposium was a highlight in the
congress year 2008 for the guest speakers,
the participants, and all of the organizers.
Accordingly, given the motto ‘‘after the
congress is before the congress’’, the
planning for the 3rd International GK
Symposium in 2010 has already begun,
and we expect that we will compile an
attractive list of speakers and attract even
more international guests to the next
Erlanger Immunology Symposium.
Carmen Kroczek1 Stefanie Thiele2 and
Rebecca Winkelmann1
1Division of Molecular Immunology,
Department of Internal Medicine III,
Nikolaus-Fiebiger-Center for Molecular
Medicine, University of Erlangen-
Numberg, Erlangen2Institute of Pharmacology and Toxicol-
ogy, University of Erlangen-Numberg,
Erlangen
www.lymphozyten.de
Correspondence: Rebecca Winkelmann,
e-mail: [email protected]
erlangen.de
Figure 5. Klaus Rajewsky (Boston, USA) andStefanie Thiele (organiser) deep in discussionat the opening night’s dinner.
EFIS Bursaries for ECI Berlin
EFIS is offering 300 travel grants at h500 each for young scientists (i.e. post-docs and PhD
students under 35 years) to attend the 2nd European Congress of Immunology (ECI 2009) in
Berlin (September 13–16, 2009; www.eci-berlin2009.com). The age limit will not strictly apply
to applicants from Eastern European countries.
To be eligible for a grant, the applicant must be the first author of an abstract submitted to
the 2nd ECI. The applicant must also be a member of an efis constituent society.
Only one grant will be allocated per person and the grant cannot be transferred.
To apply please download the application form from the travel Grant section of the ECI web site
http://www.eci-berlin2009.com/eci2009/redaktion/infos/Travel_Grants.php
and return the completed form by email to the efis secretariat ([email protected]) No later than April 1, 2009.
Awardees of the efis Travel Scholarship for the 2nd ECI will be notified by the end of May 2009 and will receive their grants
upon claim during the congress at the Travel Grant Counter. The grant will be distributed neither before nor after the Congress.
Eur. J. Immunol. 2009. 39: 339–341 FORUM 341
& 2009 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim www.eji-journal.eu