Device therapy: the future is now....Device therapy: the future is now. Author European Society of...

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Device Therapy: the future is now. Mariell Jessup MD FAHA, FACC, FESC Professor of Medicine University of Pennsylvania Philadelphia, Pennsylvania, USA

Transcript of Device therapy: the future is now....Device therapy: the future is now. Author European Society of...

Page 1: Device therapy: the future is now....Device therapy: the future is now. Author European Society of Cardiology Subject Device therapy: the future is now. Keywords Heart Failure 2015,

Device Therapy:the future is now.

Mariell Jessup MD FAHA, FACC, FESCProfessor of Medicine

University of PennsylvaniaPhiladelphia, Pennsylvania, USA

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Disclosure: Mariell Jessup MD

• Speakers Bureau:• Advisory Board:• Honorarium:

University of Pennsylvania

NONE

Page 3: Device therapy: the future is now....Device therapy: the future is now. Author European Society of Cardiology Subject Device therapy: the future is now. Keywords Heart Failure 2015,

Devicedɪˈvʌɪsnouna thing made or adapted for a particular purpose, especially a piece of mechanical or electronic equipment.

synonyms: implement, gadget, utensil, tool, appliance, piece of equipment, apparatus, piece of apparatus, piece of hardware, instrument, machine, mechanism, contrivance, contraption, invention, convenience, amenity.

Page 4: Device therapy: the future is now....Device therapy: the future is now. Author European Society of Cardiology Subject Device therapy: the future is now. Keywords Heart Failure 2015,

Heart Failure Device Therapy

• Implanted electrical devices: ICD, CRT• Mechanical circulatory support devices

– Short term versus durable devices• Valvular closure or replacement devices• Monitoring devices• Stimulation HF devices• Personal wearable devices.

Page 5: Device therapy: the future is now....Device therapy: the future is now. Author European Society of Cardiology Subject Device therapy: the future is now. Keywords Heart Failure 2015,

Heart Failure Device Therapy

• Implanted electrical devices: ICD, CRT• Mechanical circulatory support devices

– Short term versus durable devices• Valvular closure or replacement devices• Monitoring devices• Stimulation HF devices• Personal wearable devices.

Page 6: Device therapy: the future is now....Device therapy: the future is now. Author European Society of Cardiology Subject Device therapy: the future is now. Keywords Heart Failure 2015,
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Secondary Prevention

2008 ACC/AHA/HRS Guidelines for Device-Based Therapy

Page 8: Device therapy: the future is now....Device therapy: the future is now. Author European Society of Cardiology Subject Device therapy: the future is now. Keywords Heart Failure 2015,

Primary Prevention

2008 ACC/AHA/HRS Guidelines for Device-Based Therapy

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Camm and Nisam Europace (2010) 12, 1063–1069

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Masoudi et al. J Am Coll Cardiol 2013;62:1931–47

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Camm and Nisam Europace (2010) 12, 1063–1069

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17% reduction in mortality.

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ACC/AHA guidelines, 2012

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Page 16: Device therapy: the future is now....Device therapy: the future is now. Author European Society of Cardiology Subject Device therapy: the future is now. Keywords Heart Failure 2015,

Heart Failure Device Therapy

• Implanted electrical devices: ICD, CRT• Mechanical circulatory support devices

– Short term versus durable devices• Valvular closure or replacement devices• Monitoring devices• Stimulation HF devices• Personal wearable devices.

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the OPTIONS

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Sick patient

Temporary supportChronic support

Unclear situation

1. Support circulation2. Oxygenate patient

Choice dictated by clinical status:temporary supportECMO

Durable VADs pulsatile non-pulsatile

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~ ½ of the patients who need an MCSD for shock survive, and ~ ½ of these survivors require an

implantable VAD. Ongoing CPR is predictive of in- hospital

mortality.

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VADs are getting better, but heart transplant is still the gold standard.

Page 21: Device therapy: the future is now....Device therapy: the future is now. Author European Society of Cardiology Subject Device therapy: the future is now. Keywords Heart Failure 2015,

Heart Failure Device Therapy

• Implanted electrical devices: ICD, CRT• Mechanical circulatory support devices

– Short term versus durable devices• Valvular closure or replacement devices• Monitoring devices• Stimulation HF devices• Personal wearable devices.

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Mitral Clip

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“we conclude the non-inferiority of the MitraClip as a treatment for severe, symptomatic MR, in comparison to conventional valvular surgery. Despite a higher risk profile in the MitraClip patients, the

clinical outcomes were comparable although surgery was more effective in reducing MR in the early post procedure period. “

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TAVR

Page 25: Device therapy: the future is now....Device therapy: the future is now. Author European Society of Cardiology Subject Device therapy: the future is now. Keywords Heart Failure 2015,

Heart Failure Device Therapy

• Implanted electrical devices: ICD, CRT• Mechanical circulatory support devices

– Short term versus durable devices• Valvular closure or replacement devices• Monitoring devices• Stimulation HF devices• Personal wearable devices.

Page 26: Device therapy: the future is now....Device therapy: the future is now. Author European Society of Cardiology Subject Device therapy: the future is now. Keywords Heart Failure 2015,
Page 27: Device therapy: the future is now....Device therapy: the future is now. Author European Society of Cardiology Subject Device therapy: the future is now. Keywords Heart Failure 2015,

Heart Failure Device Therapy

• Implanted electrical devices: ICD, CRT• Mechanical circulatory support devices

– Short term versus durable devices• Valvular closure or replacement devices• Monitoring devices• Stimulation HF devices• Personal wearable devices.

Page 28: Device therapy: the future is now....Device therapy: the future is now. Author European Society of Cardiology Subject Device therapy: the future is now. Keywords Heart Failure 2015,
Page 29: Device therapy: the future is now....Device therapy: the future is now. Author European Society of Cardiology Subject Device therapy: the future is now. Keywords Heart Failure 2015,

Heart Failure Device Therapy

• Implanted electrical devices: ICD, CRT• Mechanical circulatory support devices

– Short term versus durable devices• Valvular closure or replacement devices• Monitoring devices• Stimulation HF devices• Personal wearable devices.

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Further understanding of information shared by the public in this forum could suggest new approaches for improving resuscitation related education.

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Thank You