DANH V. NGUYEN Curriculum Vitae July 2016 - UCI ICTS · 1 DANH V. NGUYEN Curriculum Vitae July 2016...

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1 DANH V. NGUYEN Curriculum Vitae July 2016 843 Health Sciences Road Irvine, CA 92697-1385 P(949) 824-9560 F(949) 824-3360 Email:[email protected] Google Scholar Citation: https://scholar.google.com/citations?user=NiQq4REAAAAJ&hl=en Linkedin: https://www.linkedin.com/in/danh-nguyen-3b9b3a33 EDUCATION Ph.D. (12.2000), Statistics, University of California, Davis (1997-2000) M.S. (6.1996), University of California, Riverside (1994-1997) B.A. (6.1995), University of California, Irvine (1991-1994) POSITIONS & EMPLOYMENT Current Faculty appointment: Professor Division of General Internal Medicine, Department of Medicine, UC Irvine, 4.2013-present (tenured) Directorship: Director Biostatistics, Epidemiology & Research Design Unit, Institute for Clinical and Translational Science (ICTS), UC Irvine, 4.2013- present Associate Director Statistics and Data Management Core, UC Davis Countermeasures Against Chemical Threats (CounterACT) Research Center of Excellence. 9.2012-present. (Initial Director and PI of the core) Previous Directorship: Statistics Leader/Director Statistics and Data Management, NeuroTherapeutics Research Institute (NTRI) University of California, Davis, 9.2007-9.2012 Director Data Coordinating Center, Early Autism Risk Longitudinal Investigation (EARLI) Network, UC Davis, 3.2008-5.2012 Associate Director Biostatistics, Epidemiology & Research Design Unit, Center for Clinical and Translational Science Center (CTSC), UC Davis, 2007-3.2013 Director Statistics Core, Center for Children’s Environmental Health (CCEH), UC Davis, 9.2006-9.2009 Faculty appointment:

Transcript of DANH V. NGUYEN Curriculum Vitae July 2016 - UCI ICTS · 1 DANH V. NGUYEN Curriculum Vitae July 2016...

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DANH V. NGUYEN Curriculum Vitae

July 2016

843 Health Sciences Road • Irvine, CA 92697-1385 • P(949) 824-9560 • F(949) 824-3360 • Email:[email protected] Google Scholar Citation: https://scholar.google.com/citations?user=NiQq4REAAAAJ&hl=en

Linkedin: https://www.linkedin.com/in/danh-nguyen-3b9b3a33 EDUCATION Ph.D. (12.2000), Statistics, University of California, Davis (1997-2000) M.S. (6.1996), University of California, Riverside (1994-1997) B.A. (6.1995), University of California, Irvine (1991-1994) POSITIONS & EMPLOYMENT Current Faculty appointment: Professor Division of General Internal Medicine, Department of Medicine,

UC Irvine, 4.2013-present (tenured) Directorship: Director Biostatistics, Epidemiology & Research Design Unit, Institute for

Clinical and Translational Science (ICTS), UC Irvine, 4.2013-present

Associate Director Statistics and Data Management Core, UC Davis

Countermeasures Against Chemical Threats (CounterACT) Research Center of Excellence. 9.2012-present. (Initial Director and PI of the core)

Previous Directorship: Statistics Leader/Director Statistics and Data Management, NeuroTherapeutics Research

Institute (NTRI) University of California, Davis, 9.2007-9.2012 Director Data Coordinating Center, Early Autism Risk Longitudinal

Investigation (EARLI) Network, UC Davis, 3.2008-5.2012 Associate Director Biostatistics, Epidemiology & Research Design Unit, Center for

Clinical and Translational Science Center (CTSC), UC Davis, 2007-3.2013

Director Statistics Core, Center for Children’s Environmental Health

(CCEH), UC Davis, 9.2006-9.2009 Faculty appointment:

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Adjunct Professor Division of Biostatistics, Department of Public Health Sciences, UC Davis, 4.2013-7.2016 (without salary)

Professor Division of Biostatistics, Department of Public Health Sciences,

UC Davis, 7.2011-3.2013 (Biostatistics) Associate Professor Division of Biostatistics, Department of Public Health Sciences,

UC Davis, 7.2007-6.2011 (Biostatistics) Assistant Professor Division of Biostatistics, Department of Public Health Sciences,

UC Davis, 7.2003-6.2007 (Biostatistics) Assist. Research Professor Department of Statistics, Texas A&M University, College Station, 7.2001-6.2003 (Statistics/Bioinformatics) Other Positions: Postdoctoral Researcher Center for Image Processing & Integrated Computing, UC Davis, 1.2001-7.2001 (Statistics/Bioinformatics) Instructor Department of Statistics, University of California, Davis, Summer 1999 & Spring 2000 (Statistics) Graduate Research & Department of Statistics, University of California, Davis, Teaching Assistant 9.1997-7.2000 (Statistics) Teaching Assistant Teaching Resources Center (TRC), University of California, Davis, Consultant 1998-1999 Statistical Consultant California Department of Health Services, Cancer Registry,

Sacramento, 6.1998-9.1998 (Survey Sampling, Type II Diabetes)

Graduate Teaching Department of Statistics, University of California, Riverside, Assistant 9.1995-7.1996 (Statistics) Instructor Department of Mathematics, San Bernardino Valley College, Spring 1997 (Statistics) Teaching Assistant School of Social Sciences, University of California, Irvine, 9.1993-6.1994 (Social Sciences Statistics, Statistical Computing) HONORS 1998-1999 Teaching Consultant Fellowship Award, Teaching Resources Center, UC Davis 2007-2008 Faculty Excellence Award for Teaching, Graduate Group in Epidemiology, UC

Davis (awarded by GGE students to the most outstanding faculty of the year) 2009 Paper selected by Biometrics Editor for presentation in special Biometrics

session at the Fifth Biannual Conference of the Eastern Mediterranean Region of the International Biometrics Society (“Covariate adjusted correlation analysis with

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application to FMR1 premutation female carrier data”) PROFESSIONAL AFFILIATION Profession Member, American Association for the Advancement of Science (2008-present) Member, American Statistical Association (1994-2000, 2003-2005, 2011-present) Member, Institute of Mathematical Statistics (1997-2003) University Member, UC Davis Graduate Group in Epidemiology (2006-2016) Member, UC Davis Clinical and Translational Science Center (2006-2013) Member, UC Davis Cancer Center (2003-2013) RESEARCH AREAS & INTEREST ▪ Applied statistics: applications in molecular biology, medicine, and epidemiology ▪ Bioinformatics, statistical bioinformatics ▪ Cancer classification: genomic approaches ▪ Cases series methods and analysis, case only methods (epidemiology/biostatistics methods) ▪ Categorical data analysis: Poisson modeling, zero-inflated and hurdle models ▪ Covariate adjusted regression and correlation modeling (cross-sectional and longitudinal

designs) ▪ False discovery rate, multiple testing ▪ Fragile X syndrome, fragile X premutation: molecular and clinical features, mechanism ▪ Infection, cardiovascular outcome in dialysis patients, USRDS database, dialysis facility and

hospitalization characteristics, ▪ Longitudinal analysis, sparse data, functional data ▪ Lung cancer: survival, noninvasive staging, disparities, SEER database, NIS database ▪ Measurement error modeling ▪ High-dimensional data: microarray, genomics ▪ Partial least squares: dimension reduction, classification/prediction ▪ Profiling methods for medical care providers Google Scholar Citation: http://scholar.google.com/citations?user=NiQq4REAAAAJ&hl=en RESEARCH PUBLICATION 2002 1. Nguyen, D.V., Arpat, A.B., Wang, N. and Carroll, R.J. (2002) DNA microarray experiments:

biological and technological aspects. Biometrics, 58, 701-717. PMID: 12495124 2. Nguyen, D.V. and Rocke, D.M. (2002) Classification of acute leukemia based on DNA

microarray gene expressions using partial least squares. In Methods of Microarray Data Analysis, Lin, S.M, and Johnson, K.F. (eds), Kluwer, Dordrecht, p.109-124.

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3. Nguyen, D.V. and Rocke, D.M. (2002) Tumor classification by partial least squares using microarray gene expression data. Bioinformatics, 18, 39-50. PMID: 11836210

4. Nguyen, D.V. and Rocke, D.M. (2002) Multi-class cancer classification via partial least

squares using gene expression profiles. Bioinformatics, 18, 1216-1226. PMID: 12217913 5. Nguyen, D.V. and Rocke, D.M. (2002) Partial least squares proportional hazard regression

for application to DNA microarray survival data. Bioinformatics, 18, 1625-1632. PMID: 12490447

2004 6. Nguyen, D.V., Wang, N. and Carroll, R.J. (2004) Evaluation of missing value estimation for

microarray data. Journal of Data Science, 2, 347-370. 7. Nguyen, D.V. (2004) On estimating the proportion of true null hypotheses for false

discovery rate controlling procedures in exploratory DNA microarray studies. Computational Statistics and Data Analysis, 47, 611-637.

8. Balagurunathan, Y., Wang, N., Dougherty E.R., Nguyen, D.V., Chen, Y., Bittner, M.L.,

Trent, J.M. and Carroll, R.J. (2004) Noise factor analysis for cDNA microarrays. Journal of Biomedical Optics, 9, 663-678. PMID: 15250753

9. Braga-Neto, U., Hashimoto, R., Dougherty, E.R., Nguyen, D.V. and Carroll, R.J. (2004) Is

cross-validation better than resubstitution for ranking genes? Bioinformatics, 20, 253-258. PMID: 14734317

10. Davidson, L.A., Nguyen, D.V., Hokanson, R.M., Callaway, E.S., Isett, R.B., Turner, N.D.,

Dougherty, E.R., Wang, N., Lupton, J.R., Carroll, R.J. and Chapkin, R.S. (2004) Chemopreventive n-3 polyunsaturated fatty acids reprogram genetic signatures during colon cancer initiation and progression in the rat. Cancer Research, 64, 6797-6804. PMID: 15374999

2005 11. Malgorzata, G*., Nguyen, D.V., Attor, S.N., Dougherty, E.R., Turner, N.D., Bancroft, L.K.,

Chapkin, R.S., Lupton, J.R. and Carroll, R.J. (2005) Comparing automatic and manual image processing in FLARE assay analysis for colon carcinogenesis. Statistical Applications in Genetics and Molecular Biology, 4, article 5 (p.1-19). PMID: 16646858 (*PhD student)

12. Nguyen, D.V. (2005) A unified computational framework to compare direct and sequential

false discovery rate algorithms for exploratory DNA microarray studies. Journal of Data Science, 3, 331-352.

13. Nguyen, D.V. (2005) Partial least squares dimension reduction for microarray gene

expression data with a censored response. Mathematical Biosciences, 193, 119-137. PMID: 15681279

14. Nguyen, D.V., and Rocke, D.M. (2004) On partial least squares dimension reduction for

microarray-based classification: a simulation study. Computational Statistics and Data Analysis, 46, 407-425.

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2006 15. Senturk, D. and Nguyen, D.V. (2006) Estimation in covariate-adjusted regression.

Computational Statistics and Data Analysis, 50, 3294-3310. 2007 16. Berry-Kravis, E., Goetz, C.G., Leehey, M., Hagerman, R., Zhang, L., Li, L., Nguyen, D.V.,

Hall, D., Tartaglia, N., Cogswell, J., Tassone, F. and Hagerman, P. (2007) Neuropathic features in fragile X premutation carriers. American Journal of Medical Genetics, 143A, 19-26. PMID: 17152065

17. Nguyen, D.V. and Senturk, D. (2007) Distortion diagnostics for covariate-adjusted

regression: graphical techniques based on local linear modeling. Journal of Data Science, 5, 471-490.

18. Nguyen, D.V., Liu, H. and Senturk, D. (2007) A general FDR-based computational

framework for sample size planning in microarray studies. In Advanced Computational Methods for Biocomputing and Bioimaging, Pham, T., Yan, H., and Crane, D. (eds), Nova Science Publishers, New York, p. 55-69.

19. Devaraj, S., Cheung, A.T., Jialal, I., Griffen, S.C., Nguyen, D., Glaser, N., Aoki, T. (2007)

Evidence of increased inflammation and microcirculatory abnormalities in patients with type 1 diabetes and their role in microvascular complications. Diabetes, 56, 2790-2796. PMID: 17686944 PMCID: PMC3420618

2008 20. Nguyen, D.V., Senturk, D. and Carroll, R.J. (2008) Covariate-adjusted linear mixed effects

models with an application to longitudinal data. Journal of Nonparametric Statistics, 20, 459-481. PMID: 19266053 PMCID: PMC2650843

21. Nguyen, D.V. and Senturk, D. (2008) Multicovariate-adjusted regression models. Journal of

Statistical Computation and Simulation, 78, 813-827. 22. Seritan, A., Nguyen D.V., Farias, S., Fakhri, D., Hinton, L., Grigsby, J., Bourgeois, J.A.,

Hagerman, R.J. (2008) Dementia in fragile X-associated tremor/ataxia syndrome (FXTAS): Comparison with alzheimer’s disease. American Journal of Medical Genetics: Neuropsychiatric Genetics, 147B, 1138-1144. PMID: 18384046 PMCID: PMC2898561

23. Chee, K. G.*, Nguyen, D. V., Brown, M., Gandara, D. R., Wun, T. and Lara, P. N. (2008)

Positron emission tomography and improved survival in lung cancer: The Will Rogers phenomenon revisited. Archives of Internal Medicine, 168, 1541-1549. PMID: 18663166 (*Research during fellowship)

24. Aguilar, D.C.*, Sigford, K.,Soontarapornchai, K., Nguyen, D.V., Adams, P.E., Yuhas, J.,

Hagerman, P.J. and Hagerman, R.J. (2008) A quantitative assessment of tremor and ataxia in FMR1 premutation carriers using CATSYS. American Journal of Medical Genetics, 146A, 629-635. PMID: 18241072 (*student researcher)

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25. Adams, J.S.*, Adams, P.E., Nguyen, D.V., Brunberg, J.A., Tassone, F., Zhang, W., Koldewyn, K., Rivera, S.M., Grigsby, J., Zhang, L., DeCarli, C., Hagerman, P. and Hagerman, R. (2007) Volumetric brain changes in females with fragile X associated tremor/ataxia syndrome (FXTAS). Neurology, 69, 851-859. (*student researcher) PMID: 17724287

26. Sonneborn, D., Park, H.-Y*., Petrik, J., Kocan, A., Palkovicova, L., Trnovec, T., Nguyen,

D.V. and Hertz-Picciotto, I. (2008) Prenatal polychlorinated biphenyl exposures in Eastern Slovakia modify effects of social factors on birthweight. Paediatric and Perinatal Epidemiology, 22, 202-213. PMID: 18426515 (*PhD committee advisee)

27. Sonneborn, D., Park, H.-Y*., Babinska, K., Palkovicova, L., Trnovec, T., Nguyen, D.V. and

Hertz-Picciotto, I. (2008) Serum PCB concentrations in relation to locally produced food items in Eastern Slovakia. Journal of Exposure Science and Environmental Epidemiology, 18, 581-587. PMID: 18285840 (*PhD committee advisee)

28. Verro, P., Gorelick, P. and Nguyen, D.V. (2008) Aspirin plus dipyridamole versus aspirin for

vascular events after stroke or TIA: a meta-analysis. Stroke, 39, 1358-1363. PMID: 18323511

2009 29. Nguyen, D.V. and Senturk, D. (2009) Covariate-adjusted regression for longitudinal data

incorporating correlation between repeated measurements. Australian and New Zealand Journal of Statistics, 51, 319-333.

30. Nguyen, D.V. and Senturk, D. (2009) A consistent local linear estimator of covariate

adjusted correlation. Statistics and Probability Letters, 79, 1684-1689. PMID: 21720454 PMCID: PMC3124279

31. Senturk, D., Nguyen, D.V., Tassone, F., Hagerman, R.J., Carroll, R.J. Hagerman, P.J

(2009) Covariate adjusted correlation analysis with application to FMR1 premutation female carrier data. Biometrics, 65, 781-792. PMID: 19173699 PMCID: PMC2748149

32. Senturk, D. and Nguyen, D.V. (2009) Partial covariate adjusted regression. Journal of

Statistical Planning and Inference, 139, 454-468. PMID: 20126296 PMCID: PMC2719909 33. Senturk, D. and Nguyen, D.V. (2009) Asymptotic properties of covariate-adjusted

regression with correlated errors. Statistics and Probability Letters, 79, 1175-1180. 34. Hessl, D., Nguyen, D. V., Green, C., Chavez, A., Tassone, F., Hagerman, R. J., Senturk, D.,

Schneider, A., Reiss, A. L., Lightbody, A. and Hall, S. (2009) A solution to limitations of intelligence testing in children with developmental disabilities: The case of fragile X syndrome. Journal of Neurodevelopmental Disorders, 1, 33-45. PMID: 19865612 PMCID: PMC2768415

35. Nguyen, D.V., Senturk, D., Harvey, D.J. and Li, C.-S. (2009) Sample size and power in

genomics studies. In Computational Biology: New Research, Russe, A. S. (ed), Nova Science Publishers, New York, p. 59-87.

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36. Chen, Y.* and Nguyen, D.V. (2009) Identification of relevant genes using partial least squares weights based on microarray genomics expression data. In Computational Biology: Issues and Applications in Oncology, Pham, T. (ed), Springer, New York, p. 1-17. (*PhD committee advisee)

37. Iwahashi, C., Tassone, F., Hagerman, R.J., Yasui, D., Parrott, G., Nguyen, D.V., Mayeur,

G., Hagerman, P.J. (2009) A quantitative ELISA assay for the fragile X mental retardation 1 protein. Journal of Molecular Diagnostics, 11, 281-289. PMID: 19460937 PMCID: PMC2710703

38. Coffey, S.M., Cook, K., Tartaglia, N., Tassone, F., Nguyen, D.V., Pan, R., Bronksy, H.E.,

Yuhas, J., Borodyanskaya, M., Grigsby, J., Doerflinger, M., Hagerman, P.J. and Hagerman, R.J. (2008) Expanded clinical phenotype of women with the FMR1 premutation. American Journal of Medical Genetics, 146A, 1009-1016. PMID: 18348275 PMCID: PMC2888464

39. Berry-Kravis, E., Hessl, D., Coffey, S., Hervey, C., Schneider, A., Yuhas, J., Hutchinson, J.,

Snape, M., Tranfaglia, M., Nguyen, D.V. and Hagerman, R.J. (2009) A pilot open-label single-dose trial of fenobam in adults with fragile X syndrome. Journal of Medical Genetics, 46, 266-271. PMID: 19126569

2010 40. Suga, M.J.*, Nguyen, D.V., Mohammed, S.M.+, Brown, M., Calhoun, R., Yoneda, K.,

Gandara, D.R., Lara, P.N. (2010) Racial disparities on the use of invasive and non-invasive staging in patients with non-small cell lung cancer. Journal of Thoracic Oncology, 5, 1772-1778. PMID: 20881638 (+My PhD student, *Research during fellowship)

41. Ashwood, P., Nguyen, D.V., Hessl, D., Hagerman, R.J. and Tassone, F. (2010) Plasma

cytokine profiles in fragile X subjects: Is there a role for cytokines in the pathogenesis? Brain, Behavior and Immunity, 24, 898-902. PMID: 20102735 PMCID: PMC3626458

42. Chonchaiya*, W., Nguyen, D.V., Au, J., Campos, L., Lohse, K., Mu, Y., Utari, A., Wang, L.,

Berry-Kravis, E.M., Hervey, C., Sorensen, P., Cook, K., Tassone, F., Hagerman, R.J. (2010) Clinical involvements of daughters of men with fragile X-associated tremor ataxia syndrome. Clinical Genetics, 78, 38-46. PMID: 20497189 (during postdoc/fellowship)

43. Garcia-Arocena*, D., Yang, J.E., Brouwer, J., Tassone, F., Iwahashi, C., Berry-Kravis, E.M.,

Goetz, C.G., Sumis, A.M., Zhou, L., Nguyen, D.V., Campos, L., Ludwig, A., Raske, C., Leehey, M., Greco, C., Willemsen, R., Hagerman, R.J., Hagerman, P.J. (2010) Fibroblast phenotype in male carriers of the FMR1 premutation alleles. Human Molecular Genetics, 15, 299-312. PMID: 19864489 (during postdoc)

44. Utari, A.*, Chonchaiya, W., Rivera, S.M., Schneider, A., Faradz, S., Ethell, I.M., Nguyen,

D.V. and Hagerman, R.J. (2010) Side effects of minocyline treatment in patients with fragile X syndrome and exploration of outcome measures. American Journal on Intellectual and Developmental Disabilities, 115, 433-443. PMID: 20687826 PMCID: PMC4031088 (*during fellowship)

45. Ortigas MC*, Bourgeois JA, Schneider A, Olichney J, Nguyen DV, Cogswell JB, Hall DA,

Hagerman RJ. (2010) Improving fragile X-associated tremor/ataxia syndrome symptoms

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with memantine and venlafaxine. Journal of Clinical Psychopharmacology, 30, 642-644. PMID: PMID: 20841969 PMCID: PMC4022473 (*student researcher)

46. Adams, P.E.*, Adams, J.S., Nguyen, D.V., Hessl, D., Brunberg, J.A., Tassone, F., Zhang,

W., Koldewyn, K., Rivera, S., Grigsby, J., Zhang, L., DeCarli, C., Hagerman, P.J., Hagerman, R.J. (2010) Psychological symptoms correlate with reduced hippocampal volume in fragile X premutation carriers, American Journal of Medical Genetics, 153B, 775-785. PMID: 19908235 (*student researcher)

47. Paul, R., Pessah, I.N., Gane, L., Ono, M., Hagerman, P.J., Brunberg, J.A., Tassone, F.,

Bourgeois, J.A., Adams, P.E., Nguyen, D.V., Hagerman, R.J. (2010) Early onset of neurological symptoms in fragile X carriers exposed to neurotoxins. Neurotoxicology, 31, 399-402. PMID: 20466021

48. Chonchaiya*, W., Tassone, F., Ashwood, P., Hessl, D., Schneider, A., Campos, L., Nguyen,

D.V. and Hagerman, R.J. (2010) Autoimmune disease in mothers with the FMR1 premutation is associated with seizures in their children with fragile X syndrome. Human Genetics, 128, 539-548. PMID: 20809278 PMCID: PMC2955238

49. Schwartzkroin, P.A., Wenzel, H.J., Lyeth, B.G., Poon, C.C., DeLance, A., Van, K.C.,

Campos, L. and Nguyen, D.V. (2010) Ketogenic diet modulation of seizure sensitivity and cell loss following fluid percussion injury. Epilepsy Research, 92, 74-84. PMID: 20863664

50. Kwan, J.L.*, Kluh, S., Madon, M.B., Nguyen, D.V., Barker, C.M. and Reisen, W.K. (2010)

Sentinel chicken seroconversions track tangential transmission of West Nile virus to humans in the Greater Los Angeles Area of California. American Journal of Tropical Medicine and Hygiene, 83, 1137-1145. PMID: 21036853 PMCID: PMC2963985 (*PhD committee advisee)

2011 51. Dalrymple, LS*, Mohammed SM+, Mu Y, Johansen KL, Chertow GM, Grimes B, Kaysen GA,

Nguyen DV# (2011) The risk of cardiovascular-related events following infection-related hospitalizations in older patients on dialysis. Clinical Journal of the American Society of Nephrology, 6, 1708-1713. PMID: 21566109 PMCID: PMC3133476 (During CTSC *K12 fellowship, +My PhD student, #senior author)

52. Senturk D and Nguyen DV (2011) Varying coefficient models for sparse noise-contaminated

longitudinal data. Statistica Sinica, 21, 1831-1856. 53. Cooke, D.T., Nguyen, D.V., Yang, Y., Chen, S.L., Yu, C. and Calhoun, R.F. (2010) Survival

comparison of adenosquamous, squamous cell, and adenocarcinoma of the lung after lobectomy. Annals of Thoracic Surgery, 90, 943-948. PMID: 20732522

54. Hamlin, A.*, Lui, Y., Nguyen, D.V., Tassone, F., Zhang, L., Hagerman, R.J. (2011) Sleep

apnea in premutation carriers with and without FXTAS. American Journal of Medical Genetics: Neuropsychiatric Genetics, 156, 923-928. PMID: 21932336 (*student researcher)

55. Bourgeois, J.A., Seritan, A., Casillas, E.M., Hessl, D., Schneider, A., Yang, Y., Kaur, I.,

Cogswell, J.B., Nguyen, D.V. and Hagerman, R.J. (2011) Lifetime prevalence of mood and anxiety disorders in fragile X premutation carriers. Journal of Clinical Psychiatry, 72, 175-182. PMID: 20816038 PMCID: PMC4038118

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56. Narcisa, V.*, Aguilar, D., Nguyen, D.V., Campos, L., Brodovsky, J., White, S., Adams, P.,

Tassone, F., Hagerman, P.J. and Hagerman, R.J. (2011) A quantitative assessment of tremor and ataxia in female FMR1 premutation carriers using CATSYS. Current Gerontology and Geriatrics Research, vol 2011, Article 484713, 1-7. PMCID: PMC3114433 (*student researcher)

2012 57. Mohammed SM+, Senturk D, Dalrymple DS*, Nguyen DV# (2012) Measurement error case

series models with application to infection-cardiovascular risk in older patients on dialysis. Journal of the American Statistical Association, 107, 1310-1323. PMID: 23650442 PMCID: PMC3643015 (+My PhD student, during CTSC *K12 fellowship, #senior author)

58. Maximus, S*, Nguyen, D.V., Mu, Y., Calhoun, R.F., Cooke, D.T. (2012) Size of Stage IIIA

Primary Lung Cancers and Survival: a surveillance, epidemiology and end results database analysis. The American Surgeon, 78, 1232-1237. PMID: 23089441 (*Research during residency)

59. Yoon, J.H., Nguyen, D.V., McVay, L.M., Meramo, P., Minzenberg, M.J., Ragland, J.D.,

Niendham, T., Solomon, M., Carter, C.S. (2012) Automated classification of fMRI during cognitive control identifies more severely disorganized subjects with schizophrenia. Schizophrenia Research, 135, 28-33. PMID: 22277668 PMCID: PMC3288252

60. Berry-Kravis E, Hessl D, Rathmell B, Zarevics P, Cherubini M, Walton-Bowen K, Mu Y,

Nguyen DV, Gonzales-Heydrich I, Wang P, Carpenter R, Bear M, Hagerman RJ (2012) Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with fragile X syndrome: A randomized, controlled, Phase 2 trial. Science Translational Medicine, 4, 152:127. PMID: 22993294

61. Winarni TI*, Chonchaiya W, Au J, Adams E, Mu Y, Nguyen DV, Hagerman RJ (2012)

Sertraline May Improve Language Developmental Trajectory in Young Children with Fragile X Syndrome: A Retrospective Chart Review. Autism Research and Treatment, 2012:104317, 8 pages. PMID: 22934167 PMCID: PMC3420618 (*during fellowship)

62. Winarni*, TI, Chonchaiya, W, Sumekar TA, Ashwood PA, Morales, G.M., Tassone F,

Nguyen DV, Faradz SMH, Vandewater J, Hagerman PJ, Hagerman RJ (2012) Immune-mediated disorders among female carriers of fragile X premutation alleles. American Journal of Medical Genetics, 158A, 2473-2481. PMID: 22903889 (*during fellowship)

63. Hamlin A*, Sukharev D, Campos L, Mu Y, Tassone F, Hessl D, Nguyen DV, Loesch D,

Hagerman RJ (2012) Hypertension in FMR1 premutation males with and without fragile X-associated tremor/ataxia syndrome (FXTAS). American Journal of Medical Genetics, 158A, 1304-1309. PMID: 22528549 PMCID: PMC3983689 (*student researcher)

64. Hoeffer, C., Sanchez, E., Hagerman, R.J., Mu, Y., Nguyen, D.V., Wong, H., Whelen, A.M.,

Zukin, S., Klann, E., Tassone, F. (2012) Altered mTOR signaling and enhanced CYFIP2 expression levels in subjects with fragile X syndrome. Gene, Brain and Behavior, 11, 332-341. PMID: 22268788 PMCID: PMC3319643

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65. Chonchaiya*, W., Au, J., Schneider, A., Hessl, D., Harris, S., Laird, M., Nguyen, D.V., Mu, Y., and Tassone, F., Hagerman, R.J. (2012) Increased prevalence of seizures in boys who were probands with the FMR1 premutation and co-morbid autism spectrum disorder. Human Genetics, 131, 581-589. PMID: 22001913 (*during postdoc/fellowship)

66. Tassone F, Iong KP, Tong T, Lo J, Gane LW, Berry-Kravis E, Skinner D, Bailey D, Nguyen

DV, Mu Y, Laffin J, Bailey D, Hagerman RJ, Tong T-H (2012) FMR1 CGG allele size and prevalence ascertained through newborn screening in the United States. Genome Medicine, 4, 100 (p.1-13). PMID: 23259642 PMCID: PMC4064316

67. Newschaffer CJ, Croen L, Fallin D, Hertz-Picciotto I, Nguyen DV, Lee N, Berry CA,

Farzadegan H, Hess AN, Landa RJ, Levy SE, Massolo ML, Meyerer SC, Mohammed SM*, Oliver MC, Ozonoff S, Pandey J, Schroeder A, Shedd-Wise KM (2012) Infant siblings and the investigation of autism risk factors. Journal of Neurodevelopmental Disorders, 4:7, 1-16. PMID: 22958474 PMCID: PMC3436647 (*My PhD student)

2013

68. Mohammed SM+, Dalrymple DS*, Senturk D, Nguyen DV# (2013) Design considerations for

case series models with exposure onset measurement error. Statistics in Medicine, 28, 772-786. PMID: 22911898 PMC4075338 (+My PhD student, during CTSC *K12 fellowship, #senior author) +Recipient of the 2012 Statistics in Epidemiology (SIE) Young Investigator Award, SIE section of the American Statistical Association

69. Seritan AL, Bourgeois JA, Schneider A, Mu Y, Hagerman RJ, Nguyen DV# (2013) Age of

onset of mood and anxiety disorders in fragile X premutation carriers with and without FXTAS. Current Psychiatry Review, 9, 65-71. (#senior author)

UC Irvine – Professor (tenured), Step II appointment 70. Au, J.*, Akins, R.S., Berkowitz-Sutherland, L., Tang, H.-T., Chen, Y., Boyd, A., Tassone, F.,

Nguyen, D.V., Hagerman, R.J. (2013) Prevalence and risk of migraine headaches in adult fragile X premutation carriers. Clinical Genetics, 84, 546-551. PMID: 23373759 (*student researcher)

71. Launer H*, Nguyen DV, Cooke DT (2013) National perioperative outcomes of pulmonary

lobectomy for cancer in the obese patient: A propensity score matched analysis. Journal of Thoracic and Cardiovascular Surgery, 145, 1312-1318. PMID: 23142119 (*Undergraduate student)

72. Leigh MJ*, Nguyen DV, Mu Y, Winarni TI, Hessl DR, Rivera SM, Chechi T, Polussa J,

Tassone F, Hagerman RJ (2013) A randomized double blind, placebo controlled trial of minocycline in children and adolescents with fragile X syndrome. Journal of Developmental and Behavioral Pediatrics, 34, 147-155. PMID: 23572165 PMCID: PMC3706260 (*during research fellowship)

73. Senturk D, Dalrymple DS*, Mohammed SM+, Kaysen GA, Nguyen DV# (2013) Modeling

time varying effects with generalized and unsynchronized longitudinal data. Statistics in Medicine, 32, 2971-2987. PMID: 23335196 PMCID: PMC3702655

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(+My PhD student, during CTSC *K23 fellowship, #senior author) 74. Mohammed SM+, Dalrymple DS*, Senturk D, Nguyen DV# (2013) Naïve hypothesis testing

for case series models with time-varying exposure onset measurement error: Inference for infection-cardiovascular risk in patients on dialysis. Biometrics, 69, 520-529. PMID: 23731166 (+My PhD student, *during K23 fellowship, #senior author)

2014

75. Caiozzo V, Cooper DM, Cramer S, Galassetti P, Mulnard R, Nguyen D, Ogunseitan D,

Olshansky E, Pontello A, Schneider M (2014) The institute for clinical and translational science at UC Irvine: Building an inquisitive environment where everything is questioned and there is no status quo. Clinical and Translational Science, 7(4):291-294 doi: 10.1111/cts.12177. PMID: 24898787

76. Summers SM*, Cogswell J, Goodrich J, Mu Y, Nguyen DV, Brass SD, Hagerman RJ (2014)

Prevalence of restless leg syndrome and sleep quality in carriers of the fragile X premutation. Clinical Genetics, 86(2), 181-184. (*during fellowship) PMID: 25180401

77. Summers SM*, Cogswell J, Goodrich J, Mu Y, Nguyen DV, Brass SD, Hagerman RJ (2014)

Fatigue and body mass index in the fragile X premutation carrier. Fatigue: Biomedicine, Health and Behavior, 2:2, 64-72. (*during fellowship).

78. Lozano R, Summers SD, Lozano C, Nguyen DV, Mu Y, Hessl D, Tassone F, Hagerman RJ

(2014) Association between macroorchidism and intelligence in FMR1 premutation carriers. American Journal of Medical Genetics, 164A(9):2206-1221. PMID: 24903624

79. Seritan AL, Nguyen DV, Mu Y, Tassone F, Bourgeois JA, Schneider A, Cogswell J, Cook K,

Leehey M, Grigsby J, Olichney JM, Adams P, Legg W, Zhang L, Hagerman PJ, Hagerman RJ (2014) Memantine for fragile X-associated tremor/ataxia syndrome (FXTAS): A randomized, double-blind, placebo-control trial. Journal of Clinical Psychiatry, 75, 264-271. PMID: 24345444

80. Senturk D, Ghosh S, Nguyen DV (2014) Exploratory time varying lagged regression:

Modeling association of cognitive and functional trajectories with expected clinic visits in older adults. Computational Statistics and Data Analysis, 73, 1-15. PMID: 24436504 PMCID: PMC3890149

81. Dalrymple LS*, Johansen KL, Romano PS, Chertow GM, Mu Y+, Grimes B, Kaysen GA,

Nguyen DV# (2014) Comparison of hospitalization between for-profit and nonprofit dialysis facilities. Clinical Journal of the American Society of Nephrology, 9, 73-81. PMID: 24370770 PMCID: PMC3878699 (*During K23 fellowship, +My PhD student, #senior author)

82. Senturk D, Dalrymple DS*, Mu Y+, Nguyen DV# (2014) Weighted hurdle regression method

for joint modeling of cardiovascular events likelihood and rate in the U.S. dialysis population. Statistics in Medicine, 33(25):4387-4401. PMID: 24930810 PMC4184989 (*During K23 fellowship, +My PhD student)

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83. Senturk D, *Dalrymple LS, Nguyen DV (2014) Functional linear models for zero-inflated count data with application to modeling hospitalizations in patients on dialysis. Statistics in Medicine, 33(27):4825-4840. PMID: 24942314 PMCID: PMC4221481 (*during K23 fellowship)

84. Estes Jx, Nguyen DV, Dalrymple DS*, Mu Y+, Senturk D (2014) Cardiovascular event risk

dynamics over time in older patients on dialysis: A generalized multiple-index varying coefficient model approach. Biometrics, 70, 754–764. PMID: 24766178 PMCID: PMC4209204 (+My PhD student, *during K23, xPhD Committee advisee)

2015 85. Doisy ET, Wenzel HJ, Mu Y, Nguyen DV, Schwartzkroin PA (2015) Nodule excitability in an

animal model of periventricular nodular heterotopia: c-fos activation in organotypic hippocampal slices. Epilepsia, 56(4):626-35. PMID: 25752321 PMCID: PMC4397154

86. Covarrubias N, Bhatia S, Yee S, Campos L, Nguyen DV, Fish D, Chang E (2015) The

relationship between taekwondo training habits and injury: A survey of a collegiate taekwondo population. Open Access Journal of Sports Medicine, 6, 121-127. PMID: 25960680 PMCID: PMC4410897

87. Al-Azad AS, Ghoniem GM, Leu S-Y, Nguyen DV (2015) Arabic validation of pelvic organ

prolapse/incontinence sexual questionaire, IUGA-revised (PISQ-IR). International Urogynecology Journal, 26(8):1229-37. PMID: 25800902

88. Rhee C*, Brent G, Kovesdy C, Soldin O, Nguyen DV, Budoff MJ, Brunelli S, Kalantar-Zadeh

K (2015) Hypothyroidism: An under-recognized cardiovascular risk factor in kidney disease patients? Nephrology Dialysis and Transplantation, 30(5):724-37. PMID: 24574542 (*K23 awardee) PMCID: PMC4425477

89. Ram S, Depriva I, Fenton-Farrell G, McVay L, Nguyen DV, Tassone F, Maselli R,

Hagerman RJ (2015) Axonal neuropathy in female carriers of fragile X premutation with FXTAS. Nerve and Muscle, 52(2):234-9. PMID: 25388402 PMCID: PMC4427531

90. Rhee CM*, Kim S, Gillen D, Bahattin T, Wang J, Mehrotra R, Kuttykrishnan S, Nguyen DV,

Brunelli SM, Kovesdy CP, Brent GA, Kalantar-Zadeh K (2015) Association of thyroid functional disease with mortality in a national cohort of incident hemodialysis patients. The Journal of Clinical Endocrinology & Metabolism, 100(4):1386-95. (*K23 awardee) PMID: 25632971 PMCID: PMC4516594

91. Dalrymple LS*, Mu Y+, Romano PS, Nguyen DV, Chertow GM, Delgado C, Grimes B,

Kaysen GA, Johansen KL (2015) Outcomes of infection-related hospitalization in medicare beneficiaries receiving in-center hemodialysis. American Journal of Kidney Disease, 65(5):754-62. (*K23 awardee, +My PhD student) PMID: 25641061 PMCID: PMC4414702

92. Murphy R*, Stehli A, Nguyen H, Leu S-Y, Nguyen DV, Schwarzkopf R (2015) Assessment

of dosing and patient factors on the efficacy of warfarin following total joint replacement. Open Orthop J, 15; 9:129-38. (*Medical student) PMID: 26157529 PMCID: PMC4483539

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93. Rhee CM*, Nguyen DV, Moraldi H, Brunelli SM, Dukkipati R, Jing J, Nakata T, Kovesdy CP, Brent GA, Kalantar-Zadeh K (2015) Association of adiponectin with body composition and mortality in hemodialysis patients. American Journal of Kidney Disease, 66(2):313-21. (*K23 awardee) PMID: 25824125 PMCID: PMC4516594

94. Dalrymple LS*, Mu Y+, Nguyen DV, Romano PS, Chertow GM, Grimes B, Kaysen GA,

Johansen KL (2015) Risk factors for infection-related hospitalization in in-center hemodialysis. Clinical Journal of the American Society of Nephrology (*K23 awardee, +My PhD student), Dec 7;10(12):2170-80. PMID: 26567370

2016 95. Rhee CM*, Ravel VA, Ayus JC, Sim JJ, Streja E, Mehrotra R, Amin AN, Nguyen DV,

Brunelli SM, Kovesdy CP, Kalantar-Zadeh K (2016) Pre-dialysis serum sodium and mortality in a national incident hemodialysis cohort. Nephrology, Dialysis and Transplantation, Jun;31(6):992-1001. (*K23 awardee) PMID: 26410882 PMCID: PMC4876967

UCI 9/30/15 merit to Professor, Step III (approved and effective on 7/1/16) 96. Estes JP*, Nguyen DV, Dalrymple LS, Mu Y+, Senturk D (2016) Time-varying effect

modeling with longitudinal data truncated by death: Conditional models, interpretations and inference. Statistics in Medicine, May 20;35(11):1834-47. (*PhD committee advisee, +PhD student) PMID: 26646582

97. Mikhael M, Cleary JP, Dhar V, Chen Y, Nguyen DV, Chang AC (2016) Birth tourism and neonatal intensive care: a children’s hospital experience. American Journal of Perinatology, in-press. PMID: 27183000

98. Molnar MZ, Nguyen DV, Chen Y, Ravel V, Streja E, Krishnan M, Kovesdy CP, Mehrotra R,

Kalantar-Zadeh K (2016) Predictive score for post-transplantation outcomes. Transplantation, in-press. PMID: 27391198

99. Hess LG, Fitzpatrick SE, Nguyen DV, Chen Y, Gaul K, Schneider A, Chitwood KL, Eldeeb

M, Siyahian S, Polussa J, Hessl D, Hagerman RJ (2016) A randomized double-blind, placebo-controlled trial of sertraline in young children with fragile X syndrome. Journal of Developmental & Behavioral Pediatrics, in-press.

100. Rhee CM*, Ravel VA, Streja E, Mehrotra R, Kim S, Wang J, Nguyen DV, Kovesdy CP, Brent GA, Kalantar-Zadeh K (2016) Thyroid functional disease and mortality in a national peritoneal dialysis cohort. Journal of Clinical Endocrinology & Metabolism, in-press (*K23 awardee).

101. Biegler K, Mollica R, Sim SE, Nicholas E, Chandler M, Ngo-Metzger Q, Paigne K,

Paigne S, Nguyen DV, Sorkin DH (2016) Rationale and study protocol for a multi-component health information technology (HIT) screening tool for depression and post-traumatic stress disorder in the primary care setting. Contemp Clin Trials, in-press. PMID: 27394385

Other Publication: Conference Articles (not refereed), Ph.D. Dissertation

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102. Nguyen, D.V. (2000) Statistical analysis of gene expression data from DNA microarrays based on partial least squares and related dimension reduction methods. Ph.D. dissertation in Statistics, University of California, Davis, 169 pages.

103. Nguyen, D.V. and Rocke, D.M. (2001) Assessing patient survival using microarray gene

expression data via partial least squares proportional hazard regression. Computing Science and Statistics, 33, 376-389. (Volume: http://www.interfacesymposia.org/I01/I2001HTML/index.htm)

104. Nguyen, D.V. (2004) A comparison of direct and sequential false discovery rate

algorithms: computational experiments for exploratory DNA microarray studies. Computing Science and Statistics, 36, pp. 1-15. (Volume: http://www.interfacesymposia.org/I04/index.html)

Selected manuscripts/working papers 105. Campos LF*, Senturk D, Dalrymple LS*, Nguyen DV (2014) Estimation under

misspecification of the risk period in the self-controlled case series method with application to vaccine safety studies. Submitted (*Student)

106. Estes JP*, Nguyen DV, Chen Y, Dalrymple LS, Rhee CM+, Kalantar-Zedeh K, Senturk D

(2016) Time-dynamic profiling with application to hospital readmission among patients on dialysis. Submitted (*PhD committee advisee, +K23 awardee/mentee)

107. Kandil A, Nguyen DV, Yeung ST, Campos LF, Chang EY (2015) Pain perception in

taekwondo: relationship to injury, experience and time loss. Submitted 108. Bennett K, Brown J, Robinson R, Chen Y, Nguyen DV (2015) Short-term outcomes

using blenderized tube feedings among gastrostomy dependent children. 109. Obi Y, Kalantar-Zadeh K, Wang Y, Streja E, Rhee CM, Reddy UG, Soohoo M, You AS,

Jing J, Kovesdy CP, Nguyen DV, Gillen D, Robinson B, Saran R (2016) Seasonal variations in transition, mortality, and kidney transplantation among patients with end-stage renal disease in the United States. Submitted

110. Rhee CM*, Chen Y, You SA, Brunelli SM, Kovesdy CP, Brent GA, Kalantar-Zadeh K,

Nguyen DV (2016) Thyroid functional disease, quality of life, and mental health in hemodialysis patients. Submitted (*K23 awardee/mentee)

111. Shin H-W, Zhang L, …, Nguyen DV, … (2016) Impulse Oscillometry Asthmatic Patients:

A Meta-Analysis. 112. Chou JA, Streja E, Nguyen DV, Rhee CM, Obi Y, Amin A, Kovesdy CP, Mehrotra R,

Sim JJ, Kalantar-Zadeh K (2016) Intradialytic hypotension and blood pressure changes and mortality risk in incident hemodialysis patients. Submitted

113. Peterson JK, Chen Y, Nguyen DV, Setty SP (2016) Current trends in racial, ethnic, and

risk factor disparities associated with pediatric cardiac surgery outcomes. 114. Obi Y, Streja E, Rivara MB, Rhee CM, Lau WL, Chen Y, Nguyen DV, Kovesdy CP,

Mehrotra R, Kalantar-Zadeh K (2016) Development and validation of a new correction

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equation for total serum calcium and its association with mortality among hemodialysis patients. Submitted

115. Ligsay A, Dijck AV, Nguyen DV, Lozano R, Chen Y, Bickel E, Hessl DR, Schneider A,

Angkustsiri K, Tassone F, Kooy RF, Hagerman RJ (2016) A randomized double-blind, placebo-controlled trial of ganaxolone in children and adolescents with fragile X syndrome.

116. Rhee MC, Kovesdy CP, Ravel VA, Streja E, Brunelli SM, Soohoo M, Sumida K, Molnar

MZ, Brent GA, Nguyen DV, Kalantar-Zedeh K (2016) Association of glycemic status during progression of chronic kidney disease with early dialysis mortality in diabetic patients. Submitted.

117. Schneider A, Ligsay A, Nguyen DV, Chen Y, Partington L, Summers S, Tassone F,

Seritan A, Hessl DR, Hagerman PJ, Hagerman RJ (2016) Female characteristics of fragile x-associated tremor/ataxia syndrome.

118. Kalantar-Zedeh K, Kovesdy CP, Streja E, Rhee MC, Soohoo M, Chen JLT, Molnar MZ,

Gillen D, Nguyen DV, Norris KC, Sim JJ, Jacobsen SS (2016) Transition of Care from Prelude to Renal Replacement Therapy in Chronic Kidney Disease: The Blueprints of an Emerging Field.

Unpublished manuscripts 119. Dick-Muehlke C, Chow C, Leu S-Y, Nguyen DV (2015) Crime and personal safety:

Ethnic differences in senior living needs in Orange county. 120. Mahajerin A, Nguyen DV, Chen Y, Leu, S-Y, O’Brien S (2015) Evaluation of venous

thromboembolism (VTE) mechanical prophylaxis use in pediatric trauma patients via the PHIS database.

121. Lee JH, Zamorano D, Nguyen M, Newcomb RL, Campos L, Nguyen DV (2015)

Association between gentamicin and acute renal insufficiency in trauma patients with open fractures.

122. Lee G, Leu S-Y, Nguyen DV (2015) Safety and efficacy of intravenous magnesium use

for status asthmaticus in the pediatric intensive care unit. 123. Akbari Y, Maybhate A, Chen C, Nguyen DV, Campos L, Liang L, Payton A, Jia X,

Thakor NV, Geocadin RG (2014) Orexin-A improves arousal from coma in an asphyxia cardiac arrest rodent model.

124. Hessl D, Johnson C, Mu Y, Nguyen DV (2014) Age and FMR1 characteristics on

memory among individuals with premutation. 125. Shorter J*, Nguyen DV, Mu Y, Cooke DT (2014) Bronchoalveiolar carcinoma: A

retrospective study on the survival outcomes of surgical therapy versus no surgical therapy. (*Medical student)

126. Kelly R, Fleck A, Campos L, Nguyen DV, Kain ZN (2014) Analysis of Anesthesia

Related Medical Malpractice Payments: 1995-2013.

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127. Sumekar TA, Winarni TI, Mu Y, Chonchaiya W, Adams E, Tassone F, Iwahashi C, Cheung K, Faradz MH, Hagerman PJ, Nguyen DV, Hagerman RJ (2014) Autism phenotype in fragile X premutation males is not associated with FMR1 expression: a preliminary assessment.

128. Raychaudhuri S, Mitra A, Datta A, Nguyen D, Chaudhari A, Raychaudhuri S (2013) In

vivo quantification of joint inflammation using positron emission tomography/computed tomography in murine autoimmune arthritis.

129. Chitwood KL, Greiss-Hess L, Ngotran L, Harris S, Nguyen DV, Bodine C, Hagerman RJ

(2012) AT enhancement of written expression for individuals with neurodevelopmental disorders.

130. Brunberg JA, Adams PE, Mu Y, Seritan AL, Tasson F, Boyd A, Hagerman PJ, Nguyen

DV, Hagerman RJ (2011) The insular sign in fragile X premutation carriers with and without FXTAS and association with cognitive function.

131. Adams E, Tassone F, Grigsby J, Hessl D, Nguyen DV, Hagerman RJ (2011) Assessing

motor and executive functioning in asymptomatic male carriers of the fragile X premutation. 132. Sumekar TA, Adams E, Chonchaiya W, Nguyen DV, Tassone F, Iwahashi C, Cheung K,

Hagerman PJ, Hagerman RJ (2011) Cognitive outcomes, autism and FMRP expression in fragile X premutation boys.

133. Hessl, D, Schneider, A, Iwahashi, C, Cheung, K, Rivera, SM, Tassone, F, Nguyen DV,

Hagerman, PJ (2011) Fragile X mental retardation 1 (FMR1) protein level is associated with non-verbal intelligence in healthy men.

134. Chin, A., Dalrymple, L.S.*, Kaysen, G.A., Nguyen, D.V. (2010) Assessment of

intradialytic hypertension as a risk factor in incident hemodialysis patients. (during CTSC *K12 fellowship)

135. Calhoun, R., Mayberg, S., Pevec, W., Rodriquez, V., Campos, L., Dawson, D., Young,

N., Nguyen, D.V., Laird, J. (2010) Endovascular stent repair of blunt traumatic thoracic aortic tears is first line of therapy for most patients - role of IVUS critical.

PATENT U.S. Patent No. 7,062,384: “Methods for Classifying High-Dimensional Biological Data” (with D.M. Rocke), issued June 13, 2006 GRANTS/FUNDING Current Grants/Research Support R01 DK092232 Senturk, D., Nguyen D.V. (PI’s) 02/01/16-1/31/20 NIH/NIDDK $1,354,810 (total) Title: Modeling Time Dynamic Multilevel Outcomes in Patients on Dialysis To date, there does not exist a feasible framework for estimation and dual inference (patient-and facility-level) in multilevel varying coefficient modeling (MVCM) that accommodates

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multilevel longitudinal data structures. Our work will be the first to study both patient- and facility-level inference in MVCM simultaneously and to flexibly model facility-level effects that span a spectrum of models, including facility (i) fixed effects, (ii) constant random effects, and (iii) random effects functions of time (random coefficient functions). This will also be the first study to examine continuous dialysis facility performance assessment from initiation of dialysis and allow for identification of specific time periods for targeted patient outcome improvement. Role: PI UCI subcontract UL1 TR000153 Cooper, D. (PI) 09/01/15-08/31/20 NIH/NCATS $15,135,525 (total direct) UC Irvine Institute for Clinical and Translational Science (ICTS) UC Irvine Institute for Clinical and Translational Sciences’ (ICTS) mission is to accelerate the discovery of new treatments across the spectrum of human disease/injury. The UC Irvine ICTS functions as a local centerpiece for the national program and is dedicated to accelerating scientific discovery and medical breakthroughs to the bedside. Role: Director of Biostatistics, Epidemiology ad Resign Design (BERD) Unit U54 NS079202 Lein, P. (PI) 07/01/12-06/30/17 NIH $18,378,697 (total direct) Title: Novel Anticonvulsant and Neuroprotective Therapies for TETS and OP Intoxication This is a proposal for a UC Davis Countermeasures Against Chemical Threats (CounterACT) Research Center of Excellence. The Statistics and Data Management Core's primary function will be to provide integrated research support in statistics and database applications. With respect to the statistical component, support and collaboration in experimental design and data analysis will be our main activities. We will also coordinate with the Training and Education Core, as well as the Administrative Core, to advice on statistical training for students as needed. Role: Associate Director (Initial PI/Director) of Statistics and Data Management Core (PI UCI subcontract) 2R01HD036071-14 Hagerman, R.J. (PI) 04/01/12-03/31/17 NIH/ NICHD $3,649,990 (total direct; renewal for yr 6-10) Title: Genotype-phenotype relationships in fragile X families This study address how particular forms of molecular/cellular dysregulation relate to clinical involvement, relating known molecular/cellular outcomes to the nature and severity of clinical involvement. Role: PI UCI subcontract, Co-investigator U01-DK102163 Kalantar-Zadeh, Kovesdy & Jacobsen (multiple PI) 4/01/14-3/31/19 NIH/NIDDK $2,975,182 (total) Title: Transition of Care in CKD, United Stated Renal Data System (USRDS) Special Study Center. The proposed research project aims to examine how the best transition to dialysis treatment or kidney transplantation should happen in people who have very-late-stage CKD for the best outcomes. Role: Co-investigator K23 DK102903 Rhee, C (PI) 07/01/14-06/30/19

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NIH/NIDDK $924,552 (total) Title: Hypothyroidism, Cardiovascular Health, and Survival in Kidney Disease In this career development proposal, Dr. Rhee will first examine the longitudinal impact of HT on mortality in a well-characterized prospective hemodialysis (HD) cohort in whom thyroid function will be rigorously defined using a combination of novel and traditional assays (Aim 1). She will then examine the association between HT and 3 specific CV surrogate endpoints (endothelial dysfunction, coronary artery calcification, and platelet activation) that represent major pathogenic mechanisms contributing to CHD risk in CKD (Aim 2). Lastly, she will examine the degree to which the association of HT with mortality is modified by underlying renal function in non-dialysis dependent CKD patients, and if these associations are ameliorated by thyroid hormone treatment using advanced analytic techniques (marginal structural modeling) that improve causal inference (Aim 3). Role: Mentoring team (no salary effort) IK2 CX001043 Moradi, H (PI) 04/01/14-03/31/19 VA-CDA $1,086,900 (direct) Title: HDL function and mortality in end stage renal disease Career development grant to discover novel pathways/molecules that can identify patients at high risk for CVD, particularly the roles of HLD function in ESRD patients. Role: Mentoring team (no salary effort) R01 DK101623 Sorkin, D (PI) 09/15/14-09/14/19 NIH/NIDDK $2,929,986 (total) Title: Unidas por la Vida: A Healthy Lifestyle Intervention for High-risk Latina Dyads This randomized clinical study of weight loss for two interventions: a behavioral lifestyle intervention uniquely designed to leverage the mother-daughter relationship (partner-based intervention) compared to individual-based intervention or in a usual care control group for Mexican-American mothers with type 2 diabete and Mexican-American overweight or obese adult daughters at risk for diabetes. Role: Co-Investigator

R01 HS024424 Huang, S (PI) 09/01/15-08/31/18 AHRQ $1,499,414 (total) Title:The SAFER Lines Project: Standardizing Assessment For Effective Response Evaluate the use of a standardized central line insertion site assessment (CLISA) scoring tool for early identification of locally infected central lines. Role: Co-Investigator

R40MC22641 Hagerman, R.J. (PI) 09/01/11-06/30/15 HRSA $900,000 (total direct) $61,799 (UCI subcontract total) Title: A Controlled Trial of Sertraline in Young Children with ASD This project evaluates the benefit of sertraline for treatment of early developmental delay, including language delays, social deficits and attentional deficits, in young children with autism spectrum disorder. Role: PI UCI subcontract, Co-Investigator

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DCI-201601988 Dalrymple, L. (PI) 01/01/16-12/31/17 Dialysis Clinic Inc. $10,000 (total subcontract) Title: High Risks Periods During the Course of Dialysis and the UC Davis Kidney Research Core and Collaborative Studies Role: PI UCI subcontract, Co-investigator R01 HL128801 Malik, S. (PI) 07/15/15-04/30/20 NIH $3,267,464 (total) Title: SBHW-PREDICT (The role of Proteomics, gEnetics, and Directed Imaging using CT) To assess whether identification of at-risk individuals, using imaging markers, a biomarker profile or a combination of the two, improves reclassification and discrimination over traditional risk factors, particularly in those with either a family history of coronary heart disease (CHD) or higher genetic predisposition for CHD higher genetic predisposition for CHD. Role: Statistician PR120921 Hessl, D. (PI) 01/01/13-12/31/16 Merck Foundation $996,325 Title: Cognitive Training for Fragile X Syndrome The study aim is to evaluate the efficacy of Cogmed (www.cogmed.com), a computer-based and game-oriented cognitive training program, to enhance working memory and executive functioning in patients with Fragile X Syndrome (FXS) in a randomized, double-blinded, and placebo-controlled study. Demonstration of effective Cogmed training for FXS would represent a major advancement in the field, one that may also generalize to other forms of intellectual disabilities. Role: PI UCI subcontract, Co-Investigator Completed Grants/Research Support 1R21AG047036-01 Molnar, M & Kalantar-Zadeh (multiple PI) 09/01/13-08/31/15 NIH/NIA/ NINR $424,354 (total) Title: Comparative Effectiveness of Home Hemodialysis versus Kidney Transplantation in the Elderly This comparative effectiveness research proposal will innovatively utilize new methodological approaches including propensity score based analyses to assess and to quantify the true effectiveness of kidney transplantation versus certain dialysis modalities including HHD. This 2-year project will efficiently generate a wealth of time-sensitive information about the potential treatment of choice in elderly ESRD patients that will be of immediate clinical and public health relevance and inform decision making by physicians, patients, providers, and payers. Role: Co-Investigator PR120921 Hagerman, P.J. (PI) 02/01/13-12/31/16 DOD $1,124,597 Title: Targeted Upregulation of FMRP Expression as an Approach to the Treatment of Fragile X Syndrome Our principal objectives are the identification of therapeutic targets, and the demonstration–in both fibroblasts and neuronal cells from FXS patients–that upregulation of FMRP production

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reduces/eliminates the phenotypic consequences of FMRP deficiency. Role: Co-Investigator (no salary effort, supervision of statistician) K23 DK093584 Dalrymple, L.S. (PI) 03/01/12-02/28/15 NIH/NIDDK $416,100 Title: Infection in Dialysis Patients: Risk Factors and Outcomes This career development proposal aims to: 1) identify patient-level and center-level risk factors for infection using the United States Renal Data System (USRDS), 2) examine how different dialysis center policies, practices and procedures correlate with risk of infection-related hospitalization using a nationally administered survey linked with the USRDS, and 3) describe the outcomes of infection-related hospitalization in patients on dialysis. Role: Mentoring team (no salary effort) R01DK092232-01 Senturk, D., Nguyen, D.V. (PI’s) 09/16/11-09/15/14 NIH-NIDDK $555,205 (total direct) Title: Effective semiparametric models for ultra-sparse, unsynchronized, imprecise data This study aims to develop generalized semiparametric varying coefficient models to study risk factors (e.g. infection) for outcomes (e.g., cardiovascular events) in older patients on dialysis using data from the United States Renal Data System (USRDS). Role: PI, UCI subcontract W81XWH-11-1-0626 Hagerman, R.J. (PI) 07/15/11-06/30/15 DOD/CDMRP $3,018,652 (total direct) Title: Treatment of Fragile X Syndrome with a Neuroactive Steroid This study is a Phase II trial to assess the safety, tolerability, and efficacy of ganaxolone, a GABAA agonist, for the treatment of behavioral problems including anxiety and inattention in children with FXS. Children who have the full mutation of fragile X between the ages of 6-17 years will be enrolled in this study. Role: PI UCI subcontract, Co-investigator R40MC22641-01-00 Hagerman, R.J. (PI) 09/01/11-08/31/14 HRSA $898,630 (total direct) Title: Controlled Trial of Sertraline in Young Children with Fragile X Syndrome This project evaluates the benefit of sertraline for treatment of early developmental delay, including language delays, social deficits and attentional deficits, in young children with FXS. Role: Co-investigator (UCI subcontract PI) R01HD040661 Hagerman, P.J. (PI) 11/01/11-10/31/16 NIH/NICHD $1,892,701 (total direct; renewal for yr 6-10) Title: Expression of the fragile X gene This proposal will further examine the expression of FMR1: 1) determine at the sequence-level the CGG-repeat lengths and complexity (i.e., size mosaicism) of expanded CGG-repeat FMR1 alleles; and 2) to define the dependence of FMR1 protein (FMRP) levels on CGG-repeat length and to identify at least some of the factors that control FMRP expression.

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Role: Co-investigator UC Davis Health System Chaudhari, A.J. (PI) 06/01/11-05/31/12 UC Davis – Vision grant $24,980 (total direct) Title: High resolution molecular optical imaging for early detection of Rheumatoid Arthritis The overall hypothesis is that imaging biomarkers derived from TR-LIFS will accurately identify patients with early RA and hence allow rapid commencement of appropriate treatment in diagnosed populations. Role: Collaborator (no salary effort, graduate student supervision) R01 HL105573-01A1 Kenyon, N. (PI) 12/01/11-11/30/16 NIH $1,250,000 (total direct) Title: L-arginine as a therapy in severe asthma Clinical and mechanistic study involving treatment of a subset of adult severe asthmatics; further understand the mechanisms of L-arginine metabolism and NO biology in the airways of asthmatics. Role: Co-investigator (until 4/1/13) 5UL1RR024146 Berglund, L. (PI) 07/01/11-06/30/16 NIH/NCRR $20,000,000 (total direct; renewal for years 6-10) Title: UC Davis Clinical and Translational Science Center (CTSC) The UC Davis Clinical and Translational Science Center is the academic home for innovative and collaborative medical research conducted at UC Davis and its many institutional and community partners. By cultivating a collaborative scientific environment, the center expedites the translation and integration of science from a variety of disciplines into discoveries and treatments that benefit society. Role: Associate Director/Biostatistician (25%), Design, Biostatistics and Clinical Research Ethics Core (until 4/1/13) 201016162 Ashwood, P. (PI) 06/01/11-05/31/13 Autism Speaks $769,942 (total direct) Title: Defining the underlying biology of gastrointestinal dysfunction in autism The proposed studies will examine the microbiome, metabolic phenotypes, immune responses, and the utilization of an animal model to investigate mechanisms of altered GI function. These studies will help to identify molecular pathophysiology of ASD that can inform translational research. Role: Statistician UL1 TR000153-04 Cooper, D. (PI) 07/01/10-03/31/15 NIH/NCATS $17,785,580 Title: UC Irvine Institute for Clinical and Translational Science (ICTS) UC Irvine Institute for Clinical and Translational Sciences’ (ICTS) mission is to accelerate the discovery of new treatments across the spectrum of human disease/injury. The UC Irvine ICTS functions as a local centerpiece for the national program and is dedicated to accelerating scientific discovery and medical breakthroughs to the bedside. Role: Director of Biostatistics, Epidemiology ad Resign Design (BERD) Unit (starting 4/1/13)

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S-CDHRS14 Hagerman, R.J. (PI) 02/01/10-01/31/12 National Fragile X Foundation $99,823 Title: A Double-Blind Randomized Controlled Cross Over Trial of Minocycline in Children with Fragile X Syndrome This application will provide the data to organize a large NIH controlled trial of minocycline that will involve several centers in the Fragile X Clinical and Research Consortium (FXCRC). We will use a combination of experimental paradigms and standardized measures as outcomes measures in this trial and additionally assess complications related to a 3 month double-blind controlled trial of minocycline in children with FXS. Role: Statistician (no salary effort, supervision of staff statistician & database personnel) 08-004174 Nguyen, D.V. (PI) 01/01/09-12/31/13 Autism Speaks (Subcontract Drexel University; PI Newschaffer, C.J.) $85,542 (subcontract total direct) Title: Data coordination for the Collaborative Risk and Outcome Scientific Study The objective is data sharing/collaboration between Infant Brain Imaging Study and Early Autism Risk Longitudinal Investigation Network, two NIH Autism Center of Excellence. Role: PI, UCD subcontract UL1RR024146-04S4 Berglund, L./Hagerman, R (PI) 10/29/09-06/30/10 NIH/NCRR (CTSC Administrative Supplement) $325,000 (total) Title: A Toolbox of Outcome Measures for Targeted Treatment Trials in Children Demonstrate feasibility, reliability, and utility of outcome measures for clinical trials of children with FXS, including prepulse inhibition (PPI; sensorimotor gating), standardized cognitive tests, face processing (social behavior/cognition), and visual processing (contrast detection paradigms) using infrared eyetracking technology, continuous performance tests (attention and inhibition), and an event-related brain activity measure (ERPs; sensory processing and cognitive functioning); Involve multiple CTSA sites in training for the Toolbox; Develop database and data collection standards for the Toolbox. Role Co-investigator 5R01ES016443 Nguyen, D.V. (PI) 04/01/08-03/31/13 NIEHS (subcontract Drexel University; PI Newschaffer, C.J.) $14M (total direct) $1,679,842 (subcontract total direct) Title: EARLI Network Data Coordinating Center (DCC) This study will enroll a cohort of pregnant women who have previously given birth to a child with autism to determine developmental precursors of autism in the offspring. Role: Director/PI of DCC R01 HD055510 Tassone, F. (PI) 07/1/08-06/30/13 NICHD (subcontract Univ. Washington) $464,333 (annual direct) Title: Newborn Screening in Fragile X The overall objectives of the proposed research are to further refine the rapid FMR1 DNA test, which is suitable for newborn screening from blood spots, and to utilize this test for the purpose of obtaining initial estimates of the frequency and approximate size distribution of expanded FMR1 alleles in the general population. This project will also assess immediate and extended

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family members of the identified newborn with the premutation of full mutation. This grant is part of the Fragile X Research Center P30 (3P30-HD02274-35S1; M Guralnick, P.I.). Role: Co-Investigator R01 HD036071 Hagerman, R.J. (PI) 06/15/08-03/31/12 Institute: NIH/NICHD $3,430,676 (total direct) Title: Genotype-Phenotype Relationships in Fragile X Families The proposed project represents a continuation of important and highly innovative work from one of the preeminent research groups studying Fragile X Syndrome (FXS). The application outlines a series of studies examining neurological, neuropsychiatric, and psychological problems associated with the FXS premutation in two age groups (adults and boys 6 to 18 years) and in two countries (United States and Australia). Role: Co-investigator CTSC-Pilot grant Yoon/Nguyen (co-PI) 05/01/08-04/30/09 CTSC-UC Davis $15,000 (total direct) Title: The development of an automated system for the classification of fMRI activation patterns as a diagnostic tool for the early detection of schizophrenia This is a Clinical and Translational Science Center (CTSC) New Technologies Planning Grant. Role: Co-Principal Investigator (no salary effort) U54 RR024348 Hagerman, P.J. (PI) 09/30/07-08/30/12 Institute: NIH-NCRR $21,751,234 (total direct) Title: Neurotherapeutics Research Consortium (NTRI) The primary objective is to develop targeted treatments for neurogenetic disorders. The Consortium paradigm used is the neurodegenerative disorder, fragile X-associated tremor/ataxia syndrome (FXTAS) and its neurodevelopmental counterpart, fragile X syndrome; both disorders are linked to the fragile X mental retardation 1 (FMR1) gene. The consortium consists of six components (components 2 and 4 described below). Role: Consortium Statistics Leader & Co-investigator 5RL1AG032119 Hagerman, P.J. (PI) 09/30/07-06/30/12 NIH/NIA $798,611 (annual total direct) Title: Development of Targeted Therapeutic Agents for the Treatment of FXTAS (component 2 of 6 of NTRI) The principal objective of this project will be the identification and assessment of various candidate therapeutic agents that might attenuate the effects of the pathogenic RNA in FXTAS. Research will also involve further study of neural cell models of FXTAS. Role: Investigator; Lead statistician for entire consortium. 5RL1AG032115 Hagerman, R.J. (PI) 09/30/07-06/30/12 NIH/NIA $1,208,619 (annual total direct) Title: Characterization and treatment of CNS abnormalities in premutation carriers (component 4 of 6 of NTRI)

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The overall goal of this project is to develop and utilize quantitative measures of CNS dysfunction in premutation carriers as outcome measures for targeted treatment studies of FXTAS. Role: Investigator; Lead statistician for entire consortium. R01 MH078041-01A1 Hessl, D. (PI) 06/01/07-03/31/12 Institute: NIH/NIMH $1,783,586 (total direct) Title: Limbic System Function in Carriers of the Fragile X Premutation The aim of this study is to investigate relations between molecular genetic and brain abnormalities underlying social-emotional and cognitive functioning in adult males with the fragile X premutation. The study of a relatively homogeneous single gene condition such as the fragile X premutation provides a model system for understanding links between molecular genetic, brain, and psychiatric features of more complex disorders. Role: Co-investigator R01 ES015359-01 Hertz-Picciotto, I. (PI) 01/01/07-12/31/11 NIH/NIEHS $6,178,125 (total direct) Title: The CHARGE Study: Childhood Autism Risks from Genetics and the Environment Role: Statistician UCD/MIND Hagerman, R.J. (PI) 07/01/07-06/31/08 Institute: MIND Title: Fragile X Syndrome, a Disorder of GABAergic Function: Targeted Treatment with Ganaxolone Role: Statistician K-08 Solomon, M. (PI) 04/01/07-03/31/12 NIH/NIMH Title: Cognitive Control in Autism This is a Mentored Clinical Scientist Development Award. Role: Biostatistician (no salary effort) P01 ES011269-06 Pessah, I. (PI) 10/01/06-09/30/11 NIH/NIEH $7,568,017 (total direct) Title: UC Davis Center for Children Environmental Health (CCEH; yr 6-10) The central goal of the University of California-Davis Center for Children’s Environmental Health (CCEH) is a multi-disciplinary approach to understanding the etiology of autism spectrum disorders. Role: Director of Biostatistics Core (from 2006-2009), Co-investigator U54 RR023529 Berglund, L. (PI) 09/30/06-06/30/11 NIH/NCRR $24,800,000 (total direct) Title: UC Davis Clinical and Translational Science Center (CTSC) (years 1-5) The UC Davis Clinical and Translational Science Center is the academic home for innovative and collaborative medical research conducted at UC Davis and its many institutional and community partners. By cultivating a collaborative scientific environment, the center expedites the translation and integration of science from a variety of disciplines into discoveries and

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treatments that benefit society. Working in partnership with NIH and the other centers, UC Davis serves as a discovery engine that will improve medical care by applying new scientific advances to real world practice. The goal is to ensure that new approaches to care reach health care providers, underserved populations, local community organizations and other people who need treatment. (1 of 12 inaugural members of consortium) Role: Associate Director/Biostatistician (25%), Design, Biostatistics and Clinical Research Ethics Core R01 CA11118 Kung, H.-J. PI (PI) 01/01/05-12/31/10 NIH/NCI $1,308,287 (total direct) Title: K-bZIP and Transcriptional Regulation of KSHV The objective of this project is to study the following two aims to understand in details, 1) K-bZIP as a regulator of host gene expression and 2) K-bZIP as a regulator of KSHV reactivation and replication. Role: Statistician R01 Hertz-Picciotto, I. (PI) 09/01/05-08/31/07 Institute: NIH/NCI/EPA $495,269 (total direct) Title: Early Childhood Development & PCB Exposures in Slovakia Longitudinal examination of the relationship between early childhood development, including neurodevelopment, and environmental exposure to PCBs. Role: Statistician IRG 95-125-07 Nguyen, D.V. (PI) 09/01/04-12/31/05 American Cancer Society (through UCD Cancer Center) $15,429 (total direct) Title: Sample size and power analysis for cancer biomarker identification using DNA microarray The objective of this proposal is to develop sample size method and power analysis for designing cancer biomarker identification studies using DNA microarrays. Role: Principal Investigator (no salary effort) R21 ES013066-01 Van Winkle, L. (PI) 04/01/04-03/31/07 Institute: NIH/NIEH $450,475 (total direct) Title: Prenatal Tobacco Smoke and Gene Expression in Airways Investigates the effect of pre and post-natal EST exposure on the expression of genes for metabolism and detoxification enzymes in the target organ for airborne carcinogens, the lung. Role: Co-Investigator Children’s Miracle Network/UCD Sakimura, J. (PI) 07/01/04-06/30/05 $24,462 (total) Role: Statistician (no salary effort) National Fragile X Foundation Beckett, L.A. (PI) 11/01/03-09/30/04 $20,477 (total) Title: Prevalence of Fragile X Syndrome Review of prevalence of Fragile X Syndrome and assess cost projection for the disease in the U.S.A.

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Role: Co-Investigator (no salary effort) P30 CA93373-01 deVere White, R. (PI) 07/01/02-06/30/10 NIH/NCI $850,000 (annual direct) Title: Cancer Center Support Grant P-30 The purpose is to provide support for administration, leadership and development of research programs in cancer. Role: Biostatistician PENDING Travel Awards UC Davis – 2008, 2009, 2012 TEACHING ACTIVITIES Course development (and major revision) at UC Davis

• EPI-226: Methods for Longitudinal and Repeated Measurement Data (developed as new course)

• FRS: A Leisurely Look at Genomics Research Using Microarrays (developed as new course)

• EPI-204 Statistical Models, Methods and Data Analysis (major revision to focus on epidemiology)

• EPI-204A Foundation of Statistical Models, Methods, and Data Analysis (developed) Courses Taught (Instructor of record) Course Title (Course information)

Year-Term Enrollment*

EPI-299: Dissertation Research: Profiling Methods (UC Davis, 11 units, graduate research)

2015-Spring 1 (G)

EPI-299: Dissertation Research: Profiling Methods (UC Davis, 11 units, graduate research)

2015-Winter 1 (G)

EPI-299: Dissertation Research: Profiling Methods (UC Davis, 11 units, graduate research)

2014-Fall 1 (G)

EPI-299: Dissertation Research: Profiling Methods (UC Davis, 8 units, graduate research)

2014-Spring 1 (G)

EPI-226: Methods for Longitudinal and Repeated Measurement Data (UC Davis, 3 units, graduate elective)

2011-Fall 2010-Fall 2009-Fall

1 (G) 5 (G), 4 (A)

18 (G), 4 (A)

EPI-204: Statistical Models, Methods and Data Analysis (UC Davis, 4 units, PhD core course)

2009-Spring 2008-Spring 2007-Spring

18 (G) 9 (G)

13 (G) EPP-298: Applied Longitudinal Data Analysis (UC Davis, 2 units, graduate elective)

2006-Winter 13 (G)

FRS-001: A Leisurely Look at Genomics Research Using Microarrays (UC Davis, 1 unit, undergraduate course)

2010-Winter 2009-Fall 2008-Winter

13 (U) 11 (U) 15 (U)

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2007-Winter 2005-Winter 2004-Winter

17 (U) 15 (U)

8 (U) EPI-299: Dissertation Research: Measurement Error in Case Series Method (UC Davis, 12 units, graduate research)

2012-Winter 2011-Fall 2011-Spring 2011-Winter 2010-Spring

1 (G) 1 (G) 1 (G) 1 (G) 1 (G)

EPI-299: Dissertation Research: Measurement Error in Nonlinear Models (UC Davis, 7 units, graduate research)

2010-Winter 1 (G)

EPI-299: Dissertation Research: Modeling Spatial Epidemiologic Data (UC Davis, 3 units, graduate research)

2009-Winter 1 (G)

EPI-299: Dissertation Research: Regression Modeling for PCB Exposure Data (UC Davis, 4 units, graduate research)

2006-Spring 1(G)

Internal Medicine Residency Research Practicum (UC Davis)

2007-Winter 4 IM Residents

STA-13: Elementary Statistics (UC Davis, 4 units, undergraduate course)

2004-Spring 2000-Summer

240 (U) 39 (U)

STA-32: Basic Statistical Analysis Through Computers (UC Davis, 4 units, undergraduate course)

2000-Spring 58 (U)

MATH-108: Introduction to Basic Statistics (San Bernardino Valley College, 5 units, undergraduate course)

1999-Spring 24 (U)

*G=graduate, U=undergraduate, A=auditors (faculty, research staff, postdocs, graduate students) Short Courses (# enrolled/attendees) – UC Irvine 10.28.15 3.5 hours short course Propensity Score Methods (14) 11.18.15 3.5 hours short course Clinical Prognostic Model Validation (8) Winter 201X Longitudinal Data Analysis - TBA Winter 201X Analysis of Survival Data - TBA Lectures/Workshops – UC Irvine 07.22.16 3-hours lectures/discussion (moderator: Nguyen)

Lecture 1: “Biostatistics and Study Design” (Danh Nguyen) Lecture 2: “Data Visualization and Exploratory Analysis” (Luis Campos)

Lecture 3: “Drug adherence of 6MP in a multiracial cohort of children with acute lymphoblastic leukemia” (Alice Chen) Program: California State Summer School for Mathematics and Science (COSMOS; IOR Dan Cooper)

07.21.15 3-hours lectures/discussion (moderator: Nguyen)

Lecture 1: “Biostatistics and Study Design” (Danh Nguyen) Lecture 2: “Data Visualization and Exploratory Analysis” (Luis Campos)

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Lecture 3: “Drug adherence of 6MP in a multiracial cohort of children with acute lymphoblastic leukemia” (Alice Chen) Program: California State Summer School for Mathematics and Science (COSMOS; IOR Dan Cooper)

10.09.14 1-hour lecture

“Protocol Development and Study Design” Course/Program: UC Irvine Clinical Research Coordinator Certification Preparation Series (IOR: Ruth Mulnard)

07.02.14 3-hours lectures/discussion (moderator: Nguyen)

Lecture 1: “Study Design and Randomized Controlled Study” (Danh Nguyen) Lecture 2: “Data Visualization and Exploratory Analysis” (Luis Campos)

Lecture 3: “Exploring Data: Distribution, Correlation and Association” (Sharon Leu) Program: California State Summer School for Mathematics and Science (COSMOS; IOR Dan Cooper)

06.27.14 1-hour workshop

"Fundamental of Study Design and Biostatistics: Who Wants to Be a Millionaire? Program: UCI Translational Research Day (ICTS)

11.12.13 1.5-hours lecture/discussion

“Statistical Science and Biomedical Research – Discussion of Methods for Prediction, Controls without Controls and Beyond” (Nguyen) Course: PH 194-A Clinical and Translational Research Preparatory-A (IOR, Pietro Galessetti)

11.08.13 1-hour lecture/workshop

"Biostatistics, Epidemiology and Research Design (BERD) - Services for CHOC-UCI Collaboration" (Nguyen) Program: CHOC Children’s 2013 Research Institute Week (CHOC-UCI)

07.01.13 3-hours lectures (moderator: Nguyen)

Lecture 1: “Introduction to Statistical Science – The Inseparable: Biostatistics and Biomedical Research” (Danh Nguyen)

Lecture 2: “Data Visualization and Other Fun Stuff” (Luis Campos) Lecture 3: “Exploring Data: Distribution, Correlation and Association” (Sharon Leu) Program/Program: California State Summer School for Mathematics and Science (COSMOS; IOR Dan Cooper)

06.03.13 1-hour lecture/workshop

"The ICTS BERD Compass: Navigating Statistical Analysis and Research Design in Biomedical Research" Program: Pathways to Cures: Clinical and Translational Research Day (ICTS)

Ph.D. Students

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Sandra M. Mohammed+, Ph.D. in Epidemiology. Measurement error case series models for assessing infection-cardiovascular risk in patients on dialysis in the United States, UC Davis, pp. 1-219, September 2012. [April 2009 - Aug. 2012] (Committee in charge: Danh Nguyen (Advisor), Lorien Dalrymple, Damla Senturk) +Recipient of the 2012 Statistics in Epidemiology (SIE) Young Investigator Award, SIE section of the American Statistical Association Yi (Lisa) Mu, Ph.D. program in Epidemiology (advanced to candidacy 9/15 under my supervision; changed advisor 1/16). Assessment of methods for profiling health care providers with application to monitoring outcomes of U.S. dialysis facilities, UC Davis [Sept. 2012 – Jan. 2016] (Committee in charge: Danh Nguyen (Advisor), Lorien Dalrymple, Damla Senturk – committee dissolved 1/16) Ph.D. Dissertation/Thesis Committee 2015 Jason P Estes, Ph.D. in Biostatistics, Time Dynamic Modeling and Inference

Approaches for Outcomes in Patients on Dialysis, UC Los Angeles, 12/2015. (Committee in charge: Damla Senturk (Advisor), Gang Li, Danh Nguyen, Catherine Sugar)

2010 Jennifer Wilson, Ph.D. in Epidemiology, Epidemiology and Ecology of West Nile Virus in

Los Angeles, California, UC Davis, pp. 1-135, April 2010. (Committee in charge: William Reisen (Advisor), Tim Carpenter, Danh Nguyen)

2008 Ying Chen, Ph.D. in Statistics, Statistical Approaches for Detection of Relevant Genes

and Pathways in Analysis of Gene Expression Data, UC Davis, pp. 1-136, December 2008. (Committee in charge: David Rocke (Advisor), Danh Nguyen, Katherine Pollard)

2007 Hye-Youn Park, Ph.D. in Epidemiology, Effects of PCB exposure on neurodevelopment

in children in eastern Slovakia. UC Davis, July 2007. (Committee in charge: Irva Hertz-Piciotto (Advisor), Danh Nguyen, Susan Rivera)

2006 Jingjing Ye, Ph.D. in Statistics. Preprocessing and Biomarker Detection Analysis for

Biological Mass Spectrometry Data. UC Davis, pp. 1-155, December 2006. (Committee in charge: David Rocke (Advisor), Danh Nguyen, Wolfgang Polonik)

2004 Lei Zhou, Ph.D. in Statistics. Preprocessing and Differential Expression Analysis for

Affymetrix GeneChip Arrays. UC Davis, pp. 1-126, December 2004. (Committee in charge: David Rocke (Advisor), Honzhe Li, Danh Nguyen)

M.S. Dissertation/Thesis Committee 2004 Sukhjinder Gill, M.S. in Genetics. Software for Facilitating the Encoding and Mass

Spectrometry Decoding of the “One-Bead-One-Compound” Small Molecule Combinatorial Libraries. UC Davis, pp. 1-40, June 2004. (Committee in charge: Kit S Lam (Advisor), David R Cook, Danh V Nguyen)

Ph.D. Oral Examination Committee

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2014 Jason Estes, Biostatistics, UC Los Angeles, Nov 2014. (Committee: Damla Senturk (Chair), Gang Li, Danh Nguyen, Catherine Sugar)

2010 Lindsey Holmstrom, Epidemiology, UC Davis, June 2010

(Committee: B Chomel (Chair), E Geraghty, P Kass, DV Nguyen, A Perez) 2010 Jiseok Kim, Biomedical Engineering, UC Davis, Dec. 2009 & March 2010

(Committee: C Benham (Chair), M Facciotti, DV Nguyen, DM Rocke, L Saiz) 2009 Chelsea Eastman, Epidemiology, UC Davis, April 2009

(Committee: DV Nguyen (Chair), I Gardner, S McCurdy, W Miller, K Pinkerton) 2008 Sandra Taylor, Biostatistics, UC Davis, March 2008

(Committee: DM Rocke (Chair), K Kim, I Korf, DV Nguyen, K Pollard) 2008 Terra Kelley, Epidemiology, UC Davis, March 2008

(Committee: E Gold (Chair), D Cassidy, B Chomel, DV Nguyen) 2008 Teresa Barcellos, Epidemiology, UC Davis, January 2008

(Committee: DV Nguyen (Chair), L Butler, E Gold, A De la Torre, C Walker) 2007 Seyed Reza Jafarzadeh, Epidemiology, UC Davis, July & Sept. 2007

(Committee: D Hire (Chair), J Adaska, R Atwill, W Johnson, DV Nguyen) 2007 Yolanda Hagar, Biostatistics, UC Davis, June 2007

(Committee members: F Hseih (Chair), L Beckett, D Harvey, DV Nguyen) 2005 Jingjing Ye, Statistics, UC Davis, March 2005

(Committee: W Polonik (Chair), R Azari, J Jiang, DV Nguyen, DM Rocke) M.S. Oral Examination Committee 2006 Nicole Mans, Epidemiology, UC Davis, July 2006

(Committee: T Scott (Chair), I Gardner, DV Nguyen). EDITORIAL SERVICES I have reviewed research articles for the following journals and publishers: Biostatistics/Statistics Journals

Biometrics (4): 2003, 2004, 2007, 2009 Biometrical Journal (1): 2005 Biometrika (1): 2015 Biostatistics (3): 2005(2), 2006 Communications in Statistics: Simulation and Computation (1): 2006 Communications in Statistics: Theory and Methods (5): 2008, 2009, 2010, 2011(2) Computational Statistics and Data Analysis (2): 2009, 2010 John Wiley (mathematics and statistic section of Wiley-Interscience) (1): 2002 Journal of Biopharmaceutical Statistics (1): 2004 Journal of Computational and Graphical Statistics (2): 2003, 2013 Journal of Multivariate Analysis (3): 2011(2), 2012

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Journal of the American Statistical Association (4): 2010, 2012, 2013, 2015 Journal of the Korean Statistical Society (2): 2012, 2013 Journal of the Royal Statistical Society, Series C-Applied Statistics (1): 2006 Journal of the Royal Statistical Society, Series B-Statistical Methodology (1): 2011 Pakistan Journal of Statistics (1): 2012 Scandinavian Journal of Statistics (3): 2009, 2011, 2012 Statistica Neerlandica (1): 2011 Statistica Sinica (1): 2011 Statistical Applications in Genetics and Molecular Biology (1): 2005 Statistics – CRC Press (1): 2015 Statistics in Medicine (10): 2006, 2007(2), 2009(2), 2010, 2011(2), 2012(2)

Clinical/Biomedical Sciences Journals

Biological Psychiatry (6): 2011(4), 2012(2) Clinical Investigation (1): 2013 International Journal of Developmental Neuroscience (1): 2011 Journal of Biological Chemistry (1): 2007 Journal of Clinical Epidemiology (2): 2006(2) Journal of Nutritional Biochemistry (1): 2008 Nature (6): 2012(2), 2015(2), 2016(2) Nature Medicine (1): 2003 Neoplasia (4): 2004, 2006(2), 2008 Nephrology Dialysis and Transplantation (3): 2014, 2015 (2) Neurotoxicology (2): 2009, 2013 Nucleic Acids Research (1): 2004 Scientific Reports – Nature (1): 2015

Bioinformatics Journals

Bioinformatics (26): 2003(3), 2004(1), 2005(7), 2006(8), 2007(3), 2008(3), 2009(1) BMC Bioinformatics (13): 2005(4), 2006(3), 2007(2), 2008(3), 2009(1) Briefings in Bioinformatics (1): 2006 International Journal of Data Mining and Bioinformatics (1): 2006

Computer Science/Data Mining Journals

Computational Models for Life Sciences 2007 (2): 2007(2) Computers in Biology and Medicine (1): 2008 International Journal of Pattern Recognition and Artificial Intelligence (1): 2003 Journal of Classification (2): 2009, 2011

IEEE Transactions on Nanobioscience (1): 2011 Total reviews completed: 127 Summary by year: 2002(1), 2003(7), 2004(5), 2005(15), 2006(21), 2007(11), 2008(10), 2009(10), 2010(5), 2011(17), 2012(11), 2013(5), 2014(1), 2015(7), 2016(3) Invitations to review research papers/books, which I have declined: Statistics/Epidemiology Methods Journals Advances in Statistical Analysis (1) Biometrics (1)

Communications in Statistics: Theory and Methods (4) Computational Statistics and Data Analysis (2) John Wiley-book (1),

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Journal of the American Statistical Association (5) Journal of Multivariate Analysis (3) Journal of Statistical Planning and Inference (2) Lifetime Data Analysis (1) Open Journal of Statistics (1) Pearson Education/Addison-Wesley-book (1) Statistical Applications in Genetics and Molecular Biology (10) Statistics in Biosciences (1) Statistics in Medicine (2) World Scientific Journal (1)

Bioinformatics

Advances in Bioinformatics-Special Issue guest editor (1) Bioinformatics (17) BMC Bioinformatics (16) Briefings in Bioinformatics (1) IEEE/ACM Transactions on Computational Biology and Bioinformatics (1) Transactions on Computational Biology and Bioinformatics (1)

Computer Science/Data Mining/Machine Learning

Biomedical Signal Processing & Control (1) British Journal of Mathematics and Computer Science (1)

Computers and Operations Research (1) IEEE Transactions on Nanobioscience (1) IEEE Transactions on Signal Processing (1) IET Systems Biology (1) International Journal Artificial Intelligence in Medicine (1) Journal of Machine Learning and Cybernetics (1)

Clinical/Biomedical Sciences Journals

American Journal of Epidemiology (1) Biological Psychiatry (3) BioTechniques (1) BMC Cancer (1) Expert Review of Molecular Diagnostics (1) Journal of Regenerative Medicine (1) Neoplasia (1)

Total declined to review: 90 PRESENTATIONS *Invited talks; otherwise contributed research presentations

1. 2017* Eastern North American Region of the International Biometrics Society Annual Meeting (ENAR'17 Conference), Washington, D.C. (March - TBA)

2. 2016* Computational and Methodological Statistics (9th International Conference of the ERCIM WG), Seville, Spain (Higher Technical School of Engineering of Seville, December – TBA)

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3. 2015* Association of Clinical and Translational Statistician, Seattle, WA (Aug 8, keynote)

4. 2015* Division of Biostatistics, University of California, San Diego, CA (July 1)

5. 2015 WNAR/IMS Western North American Regional Meeting of the International Biometrics Society Annual Meeting, Boise State University, Boise, Idaho (June 15)

6. 2014* A Statistical Tribute to Bob Newcomb, City of Hope, Duarte, CA (November 15)

7. 2014* International Indian Statistical Association Conference On Research Innovation

in Statistics for Health, Education, Technology, and Society, Riverside, CA (July 11)

8. 2014* WNAR/IMS Western North American Regional Meeting of the International Biometrics Society Annual Meeting, University of Hawaii at, Honolulu (June 17)

9. 2014* Pathways to Cures: Clinical Translational Research Day, University of California,

Irvine (June 27)

10. 2013* Department of Biostatistics, University of California, Los Angeles (Nov 13)

11. 2013* Children’s Hospital of Orange County (CHOC) Research Institute, Orange, CA (Nov 8)

12. 2013* Biostatistics in Clinical and Basic Research seminar, University of California,

Irvine (Sept 12)

13. 2013* Joint Statistical Meetings, American Statistical Association, Montreal, Canada (August 6)

14. 2013 WNAR/IMS Western North American Regional Meeting of the International

Biometrics Society Annual Meeting, UCLA, Los Angeles (June 19)

15. 2013* Pathways to Cures: Clinical Translational Research Day, University of California, Irvine (June 3)

16. 2012 Joint Statistical Meetings, American Statistical Association, San Diego, CA (July

31)

17. 2012* Frontiers in Biomedical Imaging Seminar, UC Davis School of Medicine, Sacramento, CA (March)

18. 2012* Institute for Clinical and Translational Science, University of California, Irvine

(February)

19. 2011* Institute for Clinical and Translational Science, University of California, Irvine (March)

20. 2009 Joint Statistical Meetings, American Statistical Association, Washington D.C.

(August)

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21. 2009 WNAR/IMS Western North American Regional Meeting of the International Biometrics Society Annual Meeting, Portland State University, Portland, Oregon (June)

22. 2009* University of California at Davis, Internal Medicine and Public Health Sciences,

Sacramento, California (March)

23. 2008 Joint Statistical Meetings, American Statistical Association, Denver, Colorado (August)

24. 2008* Sacramento Statistical Association, Annual Institute on Research and Statistics,

California State University, Sacramento, California (April)

25. 2008 Seventh Annual Hawaii International Conference on Statistics, Mathematics and Related Fields, Honolulu, Hawaii (January)

26. 2007* Sacramento Statistical Association, 28th Annual Institute on Research and

Statistics, California State University, Sacramento, California (March)

27. 2006* First Annual Bioinformatics Workshop, Department Statistics, Texas A&M, College Station, Texas, (October)

28. 2006 69th Annual Meeting of the Institute of Mathematical Statistics, Rio de Janeiro,

Brazil (July)

29. 2006 WNAR/IMS Western North American Regional Meeting of the International Biometrics Society Annual Meeting, Northern Arizona University, Flagstaff, Arizona (June)

30. 2006* Presentation to the American Cancer Society donors, UC Davis Cancer Center,

Sacramento, CA (May)

31. 2005 Joint Statistical Meetings, American Statistical Association, Minneapolis, Minnesota (August)

32. 2005* VACETS Technical International Conference 2005, Milpitas, California (June)

33. 2005* Penn State University, Department of Statistics, University Park, Pennsylvania

(February)

34. 2004 Interface 2004-Computational Biology and Bioinformatics: 36th Symposium on the Interface (INTERFACE'04 Conference), Baltimore, Maryland (May)

35. 2003 Presentation to National Cancer Institute Center for Bioinformatics (NCICB):

Cancer Biomedical Informatics Grid (caBIG), Cooperative Design Meeting, UC Davis Cancer Center, Sacramento, California, (August)

36. 2003* Summer Research Conference in Statistics: Statistics in Genetics, Molecular

Biology and Bioinformatics (The Southern Regional Council on Statistics and the American Statistical Association, SRCOS'03 Conference), The University of Georgia, Jekyll Island, Georgia (June)

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37. 2003* University of California at Davis, Department of Epidemiology and Preventive Medicine, Davis, California, (February)

38. 2003* California State University at Fullerton, Department of Mathematics, Fullerton,

California (February)

39. 2003* California State University at San Francisco, Department of Mathematics, San Francisco, California, (February)

40. 2002* IMS and International Biometric Society, Eastern North American Region

(ENAR'02 Conference), Washington, D.C. (March)

41. 2001* Texas A&M University, Bioinformatics Program, Department of Statistics, College Station, Texas, (September)

42. 2001 Interface 2001-Frontiers in Data Mining and Bioinformatics: The 33rd Symposium

on the Interface of Computing Science and Statistics (INTERFACE'01 Conference), Costa Mesa, California (June)

43. 2001* The George Washington University, Department of Statistics, Washington D.C.

(March)

44. 2001* Texas A&M University, Bioinformatics Program, Department of Statistics, College Station, Texas (March)

45. 2000* Critical Assessment of Techniques for MicroArray Data Mining (CAMDA'00

Conference), Duke University, Durham, North Carolina (December) PROFESSIONAL SERVICES National/International Conferences 06/13 Invited Speaker, Young Investigators’ Luncheon, Western North American Region of the

International Biometric Society/Institute of Mathematical Statistics (WNAR/IMS) Annual Meeting, University of California, Los Angeles, June 2013.

07/12 Session Chair, “Genomics, Genetics and Molecular Evolution” session, Joint Statistical

Meetings, San Diego, July, 2012. 02/12 Program Organizing Committee, 3rd Bi-Annual Workshop on Nutrition, Biostatistics and

Bioinformatics, Texas A&M University, College Station, February 17-18, 2012. 12/07 Program Committee, Computational Models for Life Sciences (CMLS’07), 2007

International Symposium, Gold Coast, Queensland, Australia, December 10-12, 2007. 07/06 Session Chair, “Regression Models” session, 69th Annual Meeting of the Institute of

Mathematical Statistics, Rio de Janeiro, Brazil, July 30-August 4, 2006.

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06/06 Session Chair, “General Methods/Regression” session, WNAR/IMS Western Regional Meeting of the International Biometrics Society Annual Meeting, Northern Arizona University, Flagstaff, Arizona, June 27-30, 2006.

Academic Services Scientific Review, Research/Data Safety & Monitoring 5/13 – current Director, Scientific Review of Biomedical/Clinical Research Consultation –

collaboration with UCI IRB (research involving greater than minimal risk), UC Irvine

10/03 – 3/09 Member, Clinical Trials Quality Assurance Committee (QAC), UC Davis Cancer

Center 2007 – 2009 Member, Data and Safety Monitoring Committee/Board (DSMC/DSMB), UC

Davis Cancer Center 2006 – 2008 Chair, Division of Biostatistics Research Committee (2006-2008) 3/06-4/06 External Grant Reviewer, UC Davis Academic Federation Committee on

Research, Innovative Development Award 2006-2007 Education/Teaching 1/14 – 3/14 Medical student interviews, UCISOM, Irvine 3/08 – 3/09 Co-Chair, PhD Written Examination Committee, Graduate Group in Epidemiology 6/11 – 12/11 Co-Chair, PhD Written Examination Committee, Graduate Group in Epidemiology 3/07 – 1/11 Member, Educational Policy Committee (EPC) of the Graduate Group in

Epidemiology 3/07 – 3/09 Member, PhD Written Examination Committee, Graduate Group in Epidemiology 5/06 – 2/09 Member, Division of Biostatistics Teaching Committee, Department of Public

Health Sciences 3/06 Member, School of Public Health Planning Committee: Curriculum and Student

Issues working group Faculty Review and Evaluation 4/16 Promotion review, Department of Medicine, UC Los Angeles 8/15 Promotion review, Department of Biomathematics, UC Los Angeles 3/15 Promotion review, Department of Medicine, Division of Nephrology, UC Irvine 1/15 Mid-career assessment, Department of Pediatrics, UC Irvine 12/13 Promotion review, Department of Statistics, UC Irvine

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10/13 Promotion review, Department of Medicine, Division of Nephrology, UC Irvine 8/13 Promotion review, Department of Pediatrics, UC Davis Faculty Search Committee 5/10 – 8/10 Member, Faculty Search Committee for (tenured/tenure-track)

Assistant/Associate Professor of Biostatistics, Division of Biostatistics, Department of Public Health Sciences

9/07 – 2/09 Member, Faculty Search Committee for (tenured/tenure-track) Associate/Full,

Genetic Epidemiology Faculty, Division of Epidemiology, Department of Public Health Sciences

9/07 – 11/08 Member, Faculty Search Committee for (tenured) Associate/Full Professor of

Biostatistics, Division of Biostatistics, Department of Public Health Sciences 5/06 – 6/07 Member, Faculty Search Committee for (tenured) Associate/Full Professor of

Biostatistics, Division of Biostatistics, Department of Public Health Sciences 6/06 – 6/07 Member, Faculty Search Committee for Assistant/Associate Adjunct Professor of

Biostatistics, Division of Biostatistics, Department of Public Health Sciences Other Services 2015 (July, Oct) University Expert Witness, UCLA Office of the Dean of Students 8/98 - 6/99 Graduate Teaching Consultant, Teaching Resources Center, UC Davis 8/98 – 6/99 Graduate Student/Faculty Liaison and Peer Advisor, Department of

Statistics, UC Davis 1993, Fall Quarter Undergraduate Peer Mentor, Student Support Services, University of

California, Irvine Steering and Advisory Committee Member 2/15 – current Cancer Center Biostatistics Shared Resources Advisory Committee, UC Irvine 4/13 – current Institute for Clinical and Translational Science, UC Irvine 9/12 – current Countermeasures Against Chemical Threats (CounterACT) Research

Center of Excellence, UC Davis 2/13 – 6/13 Children’s Hospital of Orange County – UC Irvine Child Health Research 9/07 – 9/12 NeuroTherapeutics Research Institute (NTRI), University of California,

Davis 3/08 – 5/12 Early Autism Risk Longitudinal Investigation (EARLI) Network, Autism

Center of Excellence, Drexel University / UC Davis / Johns Hopkins / Kaiser Permanente

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CLINICAL TRIALS Current and previous involvements in the design, analysis and/or implementation of clinical trials:

Ongoing • A controlled trial of sertraline in young children with autism spectrum disorder • Cognitive (Cogmed) training for children with fragile X syndrome • Randomized clinical study of weight loss for three interventions: a behavioral lifestyle

intervention uniquely designed to leverage the mother-daughter relationship (partner-based intervention) compared to individual-based intervention or in a usual care control

• A phase II, multicenter, randomized, open-label study to investigate the safety and efficacy of pegfilgrastim (neulasta®) in patients with alcoholic hepatitis

Completed • Treatment of fragile X syndrome with a neuroactive steroid (ganaxolone) • Controlled trial of sertraline in young children with fragile X syndrome • Memantine for fragile X-associated tremor/ataxia syndrome (FXTAS): A randomized,

double-blind, placebo-control trial • A randomized double blind, placebo controlled trial of minocycline in children and

adolescents with fragile X syndrome • Effects of STX209 (arbaclofen) on neurobehavioral function in children and adults with

fragile X syndrome: A randomized, controlled, Phase 2 trial • A pilot open-label single-dose trial of fenobam in adults with fragile X syndrome Discontinued • A Phase II, multicenter, randomized, open-label study to investigate the safety and

efficacy of mycophenolate mofetil and rilonacept (anti-interleukin-1) in patients with alcoholic hepatitis

ABSTRACTS 2002 1. Rocke, D.M., and Nguyen, D.V. (2002) Prediction and classification by partial least squares

using gene expression data. Joint Statistical Meetings-JSM 2002, New York City, NY, August 11-15.

2. Perez, R., Nguyen, D.V., Watkins, S., Johnson, J., Gandhi, M., Troppmann, C., McVicar, J.,

and Gallay, B. (2002) Pretransplant cholesterol ester fatty acids and acute rejection in renal transplantation. Journal of the American Society of Nephrology, 13, 185A.

2003 3. Dougherty, E.R., Braga-Neto, U., Hashimoto, R., Carroll, R.J., Nguyen, D.V., Bittner, M.L.,

Trent, J.M. (2003) Is cross-validation valid for microarray-based classification?

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Oncogenomics 2003-Dissecting Cancer Through Genome Research, Phoenix, AZ, January 29-February 2.

4. Williams, M.L., Carroll, R.J., and Nguyen, D.V. (2003) Summarizing FLARE assay images

in colon carcinogenesis. Joint Statistical Meetings-JSM 2003, San Francisco, CA, August 3-7.

2004 5. Nowicki, S.T., Jacquemont, S., Li, L., Nguyen, D.V., Gregg, J.P., Hagerman, R.J., and

Hagerman, P.J. (2004) An approach to identify epistatic genes involved in the development of autism spectrum disorder in patients with fragile X syndrome. Journal of Investigative Medicine, 52, S101.

6. Turner, N.D., Popovic, N., Hong, M.Y., Taddeo, S.S., Davidson, L.A., Braby, L.A., Ford, J.R., Zheng, Q., Nguyen, D.V., Carroll, R.J., Chapkin, R.S., and Lupton, J.R. (2004) Radiation enhances azoxymethane-induced colon cancer development. 3rd International Workshop on Space Radiation and 15th Annual NASA Space Radiation Health Investigators' Workshop, Port Jefferson, NY, May 16-20, pp.61.

7. Day, J., Voelbel, J., Hamstra, J., Nguyen, D.V., Pandina, G., Chiu, S., Bates, M., Hendren, R.L. (2004) Affective instability in autism. American Academy of Child and Adolescent Psychiatry (AACAP), 51th annual meeting, Washington D.C., October 19-24.

2005 8. Mannis, G., Johnsion, J., Fitzgerald, J., Warden, C., Espinal, G., Sexton, J., McVicar, J.,

Troppmann, C., Ghandi, M., Gallay, B., Nguyen, D.V., Perez, R. (2005) Pretransplant adipose tissue inflammation and serum markers of macrophage activation as predictors of acute rejection in renal transplantation. American Transplant Congress, Seattle, Washington, May 13-19, 2005.

2006 9. Sonneborn, D., Park, H.-Y., Petrik, J., Nguyen, D., Palkovicova, L. Kocan, A., Trnovec, T.,

Hertz-Picciotto, I. (2006) Prenatal PCB exposure and birth weight in eastern Slovakia. Epidemiology, 17, S410-S11.

10. Senturk, D. and Nguyen, D.V. (2006) Covariate-adjusted general linear models for longitudinal data. In: Meeting Handbook: WNAR/IMS Western Regional Meeting of the International Biometrics Society Annual Meeting, Northern Arizona University, Flagstaff, Arizona, June 27-30, 2006.

11. Senturk, D. and Nguyen, D.V. (2006) Partial covariate adjusted regression. In: Meeting Handbook: 69th Annual Meeting of the Institute of Mathematical, Rio de Janeiro, Brazil, from July 30-August 4, 2006.

12. Adams, J., Adams, P., Nguyen, D.V., Brunberg, J., Tassone, F., Hagerman, P., Hagerman, R. (2006) Brain MRI volumetric abnormalities are less severe in females carriers with

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FXTAS than in males with FXTAS. NFXF 10th International Fragile X Conference, Atlanta Georgia, July 19-23.

13. Adams, P., Adams, J., Nguyen, D.V., DeCarli, C., Hessl, D., Grigsby, J., Tassone, F.,

Hagerman, P., Hagerman, R. (2006) Women with fragile X premutation: involvement of the hippocampus. NFXF 10th International Fragile X Conference, Atlanta Georgia, July 19-23.

14. Hagerman, P, Goetz, C.G., Zhang, L., Li, L., Nguyen, D.V., Tartaglia, N., Cogswell, J.,

Farrell, G. F., Tassone, F., Maselli, R., Hagerman, R., Berry-Kravis, E. (2006) Peripheral neuropathy in fragile X-associated tremor/ataxia syndrome. Society for the Study of Behavioural Phenotype (9th SSBP International Symposium) -- Neurobiology of Behavioural Phenotypes, Dublin, Rep. of Ireland, October 19-20, 2006. (Journal of Intellectual Disability Research, 50, 793)

15. Hagerman, R., Adams, J., Adams, P., Nguyen, D.V., Hessl, D., Tassone, F., Hagerman, P.

(2006) FXTAS: A Comparison of Male vs Female Involvement. Society for the Study of Behavioural Phenotype (9th SSBP International Symposium) - Neurobiology of Behavioural Phenotypes, Dublin, Rep. of Ireland, October 19-20, 2006. Journal of Intellectual Disabilities Research, 50, 789.

2007 16. Seritan, A., Fakhri, D., Nguyen, D., Bourgeois, D., Hagerman, R. (2007) Neuropsychiatric

Features in Fragile X-Associated Tremor/ Ataxia Syndrome (FXTAS): Comparison with Alzheimer’s Disease. Journal of Intellectual Disability Research, 51, 661.

17. Van Winkle, L.S., Shultz, M., Sutherland, K., Edwards, P., Baker, G., Nguyen, D.V. (2007).

Differential gene expression by sex in airways of mice exposed to sidestream tobacco smoke. 46th Annual Meeting of the Society of Toxicology, Charlotte, North Carolina, March 25-29, 2007.

18. F. Widjaja, S. Chiu, J. Blank, G. Voelbel, G. Pandina, D. Nguyen, M. Bates, R. Hendren

(2007) Psychosis in Autism. 6th International Meeting for Autism Research (IMFAR), Seattle, Washington, May 3-5, 2007.

19. Park, H.-Y., Hertz-Picciotto, I., Sovcikova, E., Nguyen, D.V., Palkovicova, L., Kocan, A.,

Trnovec, T. (2007). Maternal PCB exposures in relation to 16-month Bayley scores. International Society for Environmental Epidemiology, Mexico City, Mexico, September 5-9, 2007.

20. Sonneborn, D., Babinska, K., Park, H.-Y., Nguyen, D.V., Palkovicova, L. Kocan, A.,

Trnovec, T., Hertz-Picciotto (2007) Association of PCB Exposure to Food-specific Consumption and Sources in Eastern Slovakia. Epidemiology, 18, S86-S87.

21. Devaraj S, Jialal I, Griffen SC, Nguyen D, Cheung A (2007) Biomarkers of inflammation and

computer assisted intravital microscopy predict microvascular complications of type 1 diabetes. Circulation, 116, 857.

2008

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22. Van Winkle, L.S., Sutherland, K., Edwards, P., Baker, G., Shultz, M., Nguyen, D.V. (2008). Sex differences in adult susceptibility to toxic challenge: Role of neonatal ETS exposures. 47th Annual Meeting of the Society of Toxicology, Seattle, Washington, March 16-20, 2008.

23. Ashwood, P., Nguyen, D.V., Hagerman, R.J. and Tassone, F. (2008) Immuno profile in

fragile X and autism. International Meeting for Autism Research (IMFAR), London, England, May 15-17, 2008.

24. Akins, R., Boyd, A., Coffey, S., Kaur, I., Bailey, B., Tassone, F., Nguyen, D.V. and

Hagerman, R. (2008) High Frequency of Migraine in FMR1 Premutation Carriers. Eleventh Annual International Fragile X Conference on Fragile, St. Louis, Missouri, June 23-27, 2008.

25. Chee, K. G., Nguyen, D. V., Brown, M., Gandara, D. R., Wun, T. and Lara, P. N. (2008)

Positron emission tomography (PET) and improved survival in non-small cell lung cancer (NSCLC) patients: The Will Rogers phenomenon revisited. Journal of Clinical Oncology, 26 (May 20 suppl; abstr 11038).

26. PE Adams, JS Adams, DV Nguyen, D Hessl, JA Brunberg, F Tassone, W Zhang, K

Koldewyn, SM Rivera, J Grigsby, L Zhang, C DeCarli, PJ Hagerman, RJ Hagerman (2008) Psychiatric problems in female fragile X premutation carriers, with involvement of the hippocampus. Eleventh Annual International Fragile X Conference on Fragile, St. Louis, Missouri, June 23-27, 2008.

27. Narcisa, V.L., Casillas, E.M., Adams, P., Yuhas, Y., Nguyen, D., Tassone, F. and

Hagerman, R. (2008) Tremor and gait ataxia in premutation females: Using CATSYS to quantitatively assess core features of FXTAS in females. Eleventh Annual International Fragile X Conference on Fragile, St. Louis, Missouri, June 23-27, 2008.

28. Chavez, A., Schneider, A., Green, C., Nguyen, D.V., Loesch, D., Gould, E. and Hessl, D.

(2008) Limitations of the standard IQ score in fragile X syndrome: A proposed solution using an individual deviation score. Eleventh Annual International Fragile X Conference on Fragile, St. Louis, Missouri, June 23-27, 2008.

29. Hessl, D., Schneider, A., Cordeiro, L., Tassone, F., Rivera, S., Nguyen, D.V., Gane, L. and

Hagerman, R. (2008) Genetic and brain correlates of psychiatric and cognitive functioning in men with the fragile X premutation. Eleventh Annual International Fragile X Conference on Fragile, St. Louis, Missouri, June 23-27, 2008.

30. Seritan, A., Nguyen D.V., Farias, S., Fakhri, D., Hinton, L., Grigsby, J., Bourgeois, J.A.,

Hagerman, R.J. (2008) Dementia in fragile X-associated tremor/ataxia syndrome (FXTAS): Comparison with Alzheimer’s disease. American Journal of Geriatric Psychiatry, 16, A112-113.

2009 31. Yoon JH, Nguyen DV, Minzenberg MH, Ursu S, Ragland JD, Carter CS (2009) The

development of an automated tool for the detection of fMRI activity pattern associated with schizophrenia. Schizophrenia Bulletin, 35, 178.

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32. Senturk, D. and Nguyen, D.V. (2009) Covariate-Adjusted Correlation Analysis with Application to FMR1 Premutation Female Carrier Data. Joint Statistical Meetings, Washington D.C., August 1-6, 2009.

33. Randi Hagerman, James Bourgeois, Andreea Seritan, Andrea Schneider, David Hessl, Ying

Yang, Danh Nguyen (2009) Psychopathology in premutation carriers: should this be added to fragile X-associated disorders? 14th International Workshop on Fragile X and X-Linked Mental Retardation, Praia do Forte, Bahia, Brazil, September 15-19, 2009.

34. Hagerman, R.J., Berry-Kravis, E., Hessl, D., Coffey, S., Schneider, A., Nguyen, D.V.,

Hervey, C., Hutchison, J. and Snape, M. (2008) Trial of fenobam, an mGluR5 antagonist, in adults with Fragile X Syndrome. Journal of Intellectual Disability Research, 52, 814.

35. Sonneborn D, Jusko T, Park H-Y, Palkovicova L, Nguyen D, Kocan A, Trnovec T, Hertz-

Picciotto I (2009) Longitudinal measures of PCBs and thymus size in infants. Epidemiology, 20, S207-S208.

36. Calhoun RF, Laird J, Mayberg S, Nguyen D, Yeo K (2009) Endovascular repair of traumatic

thoracic aortic tears is the preferred first line of therapy. American Journal of Cardiology, 104 (6A), 23D.

2010 37. Cooke, D.T., Nguyen, D.V., Ying, Y., Chen, S.L. and Calhoun, R.F. (2010) Patterns of

Presentation of Primary Adenosquamous Carcinoma of the Lung Compared to Primary Adenocarcinoma and Squamous Cell Carcinoma, and Early Stage Post-Lobectomy Survival. Society of Thoracic Surgeons 46th Annual Meeting, Fort Lauderdale, Florida, January 25-27, 2010.

38. Dalrymple, L., Chin, A., Kaysen, G., Nguyen, D.V. (2010) Intradialytic Hypertension and Mortality in Incident Hemodialysis Patients. 2010 Clinical and Translational Research and Education Meeting, Washington D.C., April 5-7.

39. M. J. Leigh, F. Tassone, G. Mendoza-Morales, D. Nguyen, A. Boyd, J. Brodovsky, C. Ruiz,

D. Hessl and R. Hagerman (2010) Evaluation of autism spectrum disorders in females with fragile X syndrome, International Meeting for Autism Research. Philadelphia, PA, May 20-22.

40. Suga, J.M., Nguyen, D.V., Mohammed, S.M., Brown, M., Calhoun, R., Yoneda, K.,

Gandara, D.R., Lara, P.N. (2010) Racial Disparities on the Use of Invasive and Noninvasive Staging in Patients with Non-Small Cell Lung Cancer (NSCLC). American Society of Clinical Oncology, 28, 7075; Chicago, Illinois, June 4-8.

41. Chonchaiya, W., Tassone, F., Ashwood, P., Hessl, D., Schneider, A., Campos, L., Nguyen,

D.V., Au, J., Hagerman, R.J. (2010) Autoimmune disease in mothers with FMR1 premutation is associated with seizures in their children with fragile X syndrome. 12th International Fragile X Conference, Detroit, Michigan, July 21-25.

42. Seritan, A.L., Bourgeois, J., Schneider, A., Nguyen, D., Hagerman, R.J. (2010) FXTAS:

Psychiatric and cognitive phenotype. 12th International Fragile X Conference, Detroit, Michigan, July 21-25.

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43. Dalrymple, L.S., Mohammed, S.M., Mu, Y., Johansen, K.L., Chertow, G.M., Grimes, B.,

Kaysen, G.A., Nguyen, D.V. (2010) Cardiovascular events following an infectious hospitalization patients on dialysis. American Society of Nephrology Annual Meeting, Denver CO, Nov 16-21, 2010.

2011 44. Long K, Tong T, Gane L, Sorensen P, Berry-Kravis E, Nguyen D, Mu Y, Skinner D, Bailey

D, Hagerman R, Tassone F (2011) Newborn screening in fragile X syndrome: prevalence and allele distribution of the FMR1 gene. American College of Medical Genetics, 2011 Annual Clinical Genetics Meeting, Vancouver, British Columbia, Canada, March 16-20, 2011.

45. Seritan A, Bourgeois J, Schneider A, Mu Y, Hagerman RJ, Nguyen DV (2011) Age of Onset

of Mood and Anxiety Disorders in Fragile X Premutation Carriers with and without FXTAS. American Psychiatric Association Annual Meeting, Honolulu, HI, May 14-18, 2011.

46. Mohammed S, Senturk D, Dalrymple LS, Nguyen DV (2011) Measurement error case series models. Western North American Region of the International Biometric Society/Institute of Mathematical Statistics (WNAR/IMS) Annual Meeting, California Polytechnic State University, San Luis Obispo, June 2011.

47. Maximus, S., Nguyen, D.V., Mu, Y., Calhoun, R.F., Cooke, D.T. (2011) Size of Primary

Tumor Matter in the Clinical Outcome of N2 Positive Stage IIIA Primary Lung Cancer After Lobectomy. World Congress on Lung Cancer, International Association of the Study of Lung Cancer, Amsterdam, the Netherlands, July 3-7, 2011.

48. Leigh MJ, Nguyen DV, Winarni TI, Hessl DR, Rivera SM, Hagerman RJ (2011) A double

blind, placebo controlled trial of minocycline in children with fragile X syndrome. Society for Developmental and Behavioral Pediatrics, September 2011.

49. Launer H, Nguyen DV, Calhoun RF, Cooke DT (2011) Pulmonary Lobectomy for Cancer in

Obese Patients is Equally as Safe as Lobectomy in Non-obese Patients. American College of Surgeons, October, 2011.

2012 50. Leigh MJ, Nguyen DV, Winarni TI, Hessl DR, Rivera SM, Schneider A, Chechi T, Polussa J,

Hagerman RJ (2012) Minocycline as a targeted treatment for fragile X syndrome. Society for Developmental and Behavioral Pediatrics, January 2012.

51. Senturk, D. and Nguyen, D.V. (2012) Varying coefficient models for sparse noise-

contaminated longitudinal data. IMS and International Biometric Society, Eastern North American Region (ENAR'12 Conference), Washington, D.C., April 2012.

52. Calhoun R, Mayberg S, Pevec W, Mu L, Nguyen D, Young N, Laird J (2012) TEVAR is

superior to open thoractomy for repair of blunt aortic injury. International Society for Minimally Invasive Cardiothoracic Surgery, 2012 Annual Scientific Meeting, Los Angeles, May 30 – June 2, 2012.

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53. M. J. Leigh, D. Nguyen, T. Winarni, A. Schneider, T. Chechi, S. M. Rivera, D. Hessl and R. J. Hagerman (2012) A Placebo-Controlled, Double-Blinded Study of Minocycline in Children with Fragile X Syndrome. International Meeting for Autism Research (5th Annual IMFAR), Montreal, Canada, June 2012.

54. Newschaffer CJ, Croen LA, Fallin MD, Hertz-Picciotto, Farzadegan H, Nguyen D (2012)

The EARLI study as a resource for autism etiologic research. International Meeting for Autism Research (5th Annual IMFAR), Montreal, Canada, June 2012.

55. Senturk D, Nguyen DV (2012) Varying coefficient models for sparse noise-contaminated

longitudinal data. 8th World Congress in Probability and Statistics, Istanbul, Turkey, July 2012.

56. Mohammed SM, Dalrymple DS, Senturk D, Nguyen DV (2012) Design considerations for

case series models with time-varying exposure onset measurement error. Joint Statistical Meetings-JSM 2012, San Diego, CA, July 28 – Aug. 2, 2012

57. Newschaffer CJ, Croen LA, Fallin MD, Hertz-Picciotto, Farzadegan H, Nguyen D (2012)

The EARLI study as a resource for research on autism and the environment. International Society for Environmental Epidemiology (ISEE), Columbia, South Carolina, August 2012.

58. M. J. Leigh, D. Nguyen, T. Winarni, D. Hessl S. M. Rivera, and R. J. Hagerman (2012) A

Placebo-Controlled, Double-Blinded Study of Minocycline in Children with Fragile X Syndrome. Journal of Investigative Medicine, 60, 126.

59. Doisy ET, Wenzel HJ, Nguyen DV, Schwartzkroin PA (2012) Perivenricular nodular

heterotopia c-fos activation in organotypic hippocampal slice cultures. American Epilepsy Society Annual Meeting, San Diego, CA, December 2012.

2013 60. Kelly RJ, Campos L, Nguyen DV (2013) A Comparison of Inpatient and Outpatient

Anesthesia Claims Reported to the National Practitioner Data Bank. American College of Legal Medicine. Dec. 2013.

61. Tancredi DJ, Nguyen DV, Cook K (2013) An integrated approach to statistical and database

support for the UC Davis counterACT center of excellence. NIH 7th Annual CounterACT Network Research Symposium, Bethesda, MD, June 25-27.

62. Campos L, Senturk D, Nguyen DV (2013) A solution to the misspecification of the optimal

risk period in the self-controlled case series method with application to vaccine safety. Western North American Region of the International Biometric Society/Institute of Mathematical Statistics (WNAR/IMS) Annual Meeting, University of California, Los Angeles, June 2013.

63. Senturk D, Estes J, Dalrymple L, Mu Y, Nguyen DV (2013) Understanding Cardiovascular Event Risk Dynamics Over Time in Older Patients on Dialysis: A Generalized Multiple-Index Varying Coefficient Model Approach. Joint Statistical Meetings-JSM 2013, Montreal, Canada, August 3-8.

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64. LS Dalrymple, KL Johansen, PS Romano, GM Chertow, Y Mu, JH Ishida, B Grimes, GA Kaysen, DV Nguyen (2013) Comparison of Hospitalization between For-Profit and Nonprofit Dialysis Facilities. American Society of Nephrology Annual Meeting, November 2013.

2014 65. Shorter JM, Nguyen DV, Mu L, David EA, Cooke DT (2014) Early stage primary

bronchioloalveolar carcinoma of the lung: a retrospective population analysis of survival for patients treated with or without surgery stratified by age. Journal of the American College of Surgeons, 219, Supplement, Pages e4–e5

66. A.C. Arrieta, M. Cheung, P.J. Van Winkle, S.A. Osborne, D.V. Nguyen, S. Leu, L. Campos, D.J. Nieves (2014) Invasive Pneumococcal Disease After Implementation Of 13-Valent Pneumococcal Conjugate Vaccine In Orange County, California. Four Year Interim Report. European Society For Paediatric Infectious Diseases, May, 2014, Dublin, Ireland.

67. CM Rhee, H Moradi, SM Brunelli, J Jing, T Nakata, D Nguyen, CP Kovesdy, GA Brent, K

Kalantar-Zadeh (2014) Relationship between Adiponectin and Body Composition in Maintenance Hemodialysis Patients: Initial Results from the MADRAD Study. International Congress on Nutrition and Metabolism in Renal Disease, Wurzburg, Germany, May 6-10, 2014.

68. CM Rhee, H Moradi, SM Brunelli, J Jing, T Nakata, D Nguyen, CP Kovesdy, GA Brent, K Kalantar-Zadeh (2014) Association Between Adiponectin and Mortality in Hemodialysis Patients from the MADRAD Study. 51st European Renal Association-European Dialysis and Transplantation Association Conference, Amsterdam, The Netherlands, May 31 - June 1 2014.

69. Campos LF, Senturk D, Dalrymple LS, Nguyen DV (2014) Estimation under misspecification of the risk period in the self-controlled case series method with application to vaccine safety studies. Western North American Region of the International Biometric Society/Institute of Mathematical Statistics (WNAR/IMS) Annual Meeting, University of Hawaii at Manoa, Honolulu, June 17 2014.

70. Senturk D, Dalrymple LS, Nguyen DV (2014) Functional linear models for zero-inflated

count data with application to modeling hospitalizations in patients on dialysis. Western North American Region of the International Biometric Society/Institute of Mathematical Statistics (WNAR/IMS) Annual Meeting, University of Hawaii at Manoa, Honolulu, June 17 2014.

71. Austin AT, Hulsizer S, Pessah IN, Harvey DJ, Nguyen DV, Tancredi DJ (2014) Statistical

approaches to characterizing neural synchrony. NIH 8th Annual CounterACT Network Research Symposium, University of Colorado Anschutz Medical Campus, Denver, Colorado. June 17-19.

72. Senturk D, Estes J, Dalrymple L, Mu Y, Nguyen DV (2014) Cardiovascular Risk Dynamics Over Time in Older Patients on Dialysis: A Generalized Multiple-Index Varying Coefficient Model Approach. International Indian Statistical Association Conference on Research Innovation in Statistics for Health, Education, Technology, and Society, Riverside, California, July 11-13.

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73. Soohoo M, Streja E, Rhee CM, Nakata T, Jing J, Kovesdy C, Nguyen D, Gillen D, Kalantar-Zadeh K (2014) Association of Depression and Ethnicity with Survival in Hemodialysis Patients: Findings from the MADRAD Study. American Society of Nephrology Annual Meeting, Philadelphia, PA, Nov 11-16.

74. Rhee CM, Kukkipati R, Moradi H, Brunelli S, Jing J, Nakata T, Nguyen D, Kovesdy C, Brent

G, Kalantar-Zadeh K (2014) Association of Adiponectin with Serum Lipids and Body Composition Surrogates in Hemodialysis Patients. American Society of Nephrology Annual Meeting, Philadelphia, PA, Nov 11-16.

75. Rhee CM, Wang J, Bahattin T, Kim S, Gillen D, Mehrotra R, Streja E, Nguyen D, Brunelli S,

Kovesdy C, Brent G, Kalantar-Zadeh K (2014) Baseline and Longitudinal Patterns of Thyroid Function across Race and Ethnicity in a National Incident Hemodialysis Cohort. American Society of Nephrology Annual Meeting, Philadelphia, PA, Nov 11-16.

2015 76. Mahajerin A, Leu S-Y, Nguyen DV, O’Brien S (2015) Evaluation of Venous

Thromboembolism Mechanical Prophylaxis Use in Pediatric Trauma Patients, Haemophilia, 21:3, E269.

77. Rhee CM, Brent G, Nguyen D, Jing J, Nakata T, Streja E, Leung A, Kovesdy C, Kalantar-

Zadeh K (2015) Relationship between thyrotropin and free thyroxine measured by tandem mass spectrometry and immunoassay in hemodialysis patients. American Journal of Kidney Diseases, 4, pg A72.

78. Chen Y, Harvey D, Nguyen DV, Hulsizer S, Pessah IN, Tancredi DJ (2015) Targeted

statistical support for UC Davis CounterACT Research. NIH 9th Annual CounterACT Network Research Symposium, New York City, June 15-17.

79. Johnson C, Pathare J, Schenk J, Shen V, Leu S-Y, Nguyen DV (2015) The use of complimentary and alternative medicine (CAM) in children diagnosed. American Society for Pediatric Hematology/Oncology's Annual Meeting, May 6-9, Phoenix AZ.

80. Hagerman R, Gaul K, Siyahian S, Hess LG, Fitzpatrick S, Schneider A, Polussa J, Eldeeb

M, Willis L, Burris J, Kahlon A, Hessl D, Rivera S, Nguyen D, Tassone F (2015) Targeted treatment in early childhood in children with FXS: A controlled trial of sertraline. 17th International Fragile X and other Early-Onset Cognitive Disorders Workshop, Strasbourg, France, Sept. 27.

(----- UCI 9/30/15 -----) 81. Bennett K, Brown J, Robinson R, Chen Y, Nguyen DV (2015) Short Term Outcomes Using

Blenderized Tube Feedings Among Gastrostomy Dependent Children. North American Society of Pediatric Gastroenterology, Hepatology and Nutrition, Washington D.C., October 7-11, 2015.

82. Molnar M, Ravel V, Streja E, Kovesdy CP, Nguyen DV, Mehrotra R, Kalantar-Zadeh K (2015) Survival of Elderly Incident Home Hemodialysis and Kidney Transplant Patients. J Am Soc Nephrol, 26. (Annual Meeting, San Diego, CA, Nov 3-8, 2015)

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83. Molnar M, Nguyen DV, Ravel V, Streja E, Krishnan M, Chen Y, Kovesdy CP, Kalantar-Zadeh K (2015) Novel Score to Predict Post-Transplant Outcomes. American Society of Nephrology 26. (Annual Meeting, San Diego, CA, Nov 3-8, 2015)

84. Rhee C, Streja E, Soohoo M, Rhee C, Obi Y, Jing J, Nguyen DV, Kashyap ML, Kovesdy

CP, Kalantar-Zedeh K (2015) The impact of pre-esrd glycemic status on early post-esrd mortality among US veterans: A transition of care in CDK study. J Am Soc Nephrol, 26. (Annual Meeting, San Diego, CA, Nov 3-8, 2015)

85. Streja E, Soohoo M, Jing J, Nguyen DV, Brunelli SM, Kovesdy CP, Kalantar-Zedeh K

(2015) Serum Triglyceride Levels during Progression to ESRD and Early Dialysis Mortality among U.S. Veterans: A Transition of Care in CKD Study. J Am Soc Nephrol, 26. (ASN Annual Meeting, San Diego, CA, Nov 3-8, 2015)

86. Dalrymple, LS, Grimes B, Romano P, Mu Y, Nguyen DV, Johansen KL (2015) Hospital

Readmission within 30 Days of Discharge among Adults Receiving Dialysis. American Society of Nephrology Annual Meeting, J Am Soc Nephrol, 26. (ASN Annual Meeting, San Diego, CA, Nov 3-8, 2015)

87. Rhee C, Streja E, Ravel VA, Streja E, Mehrotra R., Kim SM, Wang J, Nguyen DV, Brunelli

SM, Kovesdy CP, Brent G, Kalantar-Zedeh K (2015) Thyroid Functional Disease and Mortality in a National Peritoneal Dialysis Cohort. J Am Soc Nephrol, 26. ASN (Annual Meeting, San Diego, CA, Nov 3-8, 2015)

88. Rhee C, Kim SM, Mehrotra R, Streja E, Nguyen DV, Brunelli SM, Brent G, Kovesdy CP,

Kalantar-Zedeh K (2015) Predictors of Glycemic Status and Associations with Mortality in Incident Diabetic Hemodialysis Patients. J Am Soc Nephrol, 26. (ASN Annual Meeting, San Diego, CA, Nov 3-8, 2015)

89. Streja E, Soohoo M, Chen JTL, Tortorici AR, Jing J, Nguyen DV, Kovesdy CP, Kalantar-

Zedeh K (2015) Associations of Prelude (Pre-ESRD) Serum Phosphorous Levels prior to Transition to Dialysis and Early Dialysis Mortality Among U.S. Veterans: A Transition of Care in CKD Study. J Am Soc Nephrol, 26. (ASN Annual Meeting, San Diego, CA, Nov 3-8, 2015)

90. Tortorici AR, Obi Y, Soohoo M, Rhee C, Streja E, Jing J, Saran RRobinson BM, Li Y,

Nguyen DV, Norris KC, Kovesdy CP, Kalantar-Zedeh K (2015) Associations of Prelude (Pre-ESRD) BMI and Weight Change with Early Dialysis Mortality Among U.S. Veterans: A Transition of Care in CKD Study. J Am Soc Nephrol, 26. (ASN Annual Meeting, San Diego, CA, Nov 3-8, 2015)

91. Soohoo M, Rhee C, Ravel VA, Streja E, Jing J, Nguyen DV, Kovesdy CP, Kalantar-Zedeh K

(2015) Association of Pre-ESRD Hemoglobin with Early Post-ESRD Mortality Among U.S. Veterans: A Transition of Care in CKD Study. J Am Soc Nephrol, 26. (ASN Annual Meeting, San Diego, CA, Nov 3-8, 2015)

92. Soohoo M, Rhee C, Ravel VA, Streja E, Jing J, Saran R, Robinson BM, Li Y, Nguyen DV,

Kovesdy CP, Kalantar-Zedeh K (2015) Association of 6-Month Pre-ESRD Potassium with Immediate Post-ESRD Survival: A Transition to CKD Study. J Am Soc Nephrol, 26. (ASN Annual Meeting, San Diego, CA, Nov 3-8, 2015)

2016

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93. Bolurchi M, Chen Y, Pierangelo R, Nguyen DV, Wang R (2016) Aortic root dilatation in

mucopolysaccharidosis. Molecular genetics and metabolism, 2(117), S29.

94. Saran R, Li Y, Robinson B, Abbott KC, Agodoa LY, Ayanian J, Bragg-Gresham J, Balkrishnan R, Chen JL, Cope E, Eggers PW, Gillen D, Gipson D, Hailpern SM, Hall YN, He K, Herman W, Heung M, Hirth RA, Hutton D, Jacobsen SJ, Kalantar-Zadeh K, Kovesdy CP, Lu Y, Molnar MZ, Morgenstern H, Nallamothu B, Nguyen DV, O'Hare AM, Plattner B, Pisoni R, Port FK, Rao P, Rhee CM, Sakhuja A, Schaubel DE, Selewski DT, Shahinian V, Sim JJ, Song P, Streja E, Kurella Tamura M, Tentori F, White S, Woodside K, Hirth RA (2016) US Renal Data System 2015 Annual Data Report: Epidemiology of Kidney Disease in the United States. Am J Kidney Dis. 2016 Mar; 67(3 Suppl 1):A7-8. PMID: 26925525

95. Rhee C, You A, Nguyen D, Jing J, Nakata T, Streja E, Budoff M, Kovedy C, Brent G, Kalantar-Zadeh K (2016) Thyroid function and mortality risk in a prospective hemodialysis cohort: findings from the madrad study. National Kidney Foundation Meeting, Am J Kidney Dis 2016;67(5):A1-A118 (National Kidney Foundation Meeting, April 27 – May 1, 2016, Boston).

96. Rhee C, You A, Jing J, Nakata T, Lopez N, Lou L, Veliz M, Hernandez M, Budoff M,

Nguyen D, Kalantar-Zadeh K (2016) Relationship between soluble p-selectin levels and clinical characteristics in a prospective hemodiaylsis cohort. Am J Kidney Dis 2016;67(5):A1-A118 (National Kidney Foundation Meeting, April 27 – May 1, 2016, Boston).

97. Rhee C, Chen, Y, You A, Jing J, Nakata T, Kovedy C, Nguyen D, Kalantar-Zadeh K (2016)

Relationship between depression and health-related quality of life in a prospective hemodialysis cohort. Am J Kidney Dis 2016;67(5):A1-A118 (National Kidney Foundation Meeting, April 27 – May 1, 2016, Boston).

98. Li S, Harvey D, Zolkowska D, Seth S, Miller G, Lein P, Nguyen DV, Tancredi D (2016)

Regression models for estimating exposure-outcome effects in CounterACT experiments. . NIH 10th Annual CounterACT Network Research Symposium, UC Davis, June 15-17.

99. Haidar YM, Tripathi PB, Walia S, Mahboubi H, Zhang L, Nguyen DV, Tjoa J, Goddard JA

(2016) Duration of Antibiotic Prophylaxis in Clean Contaminated Head and Neck Microvascular Flap Cases: A Systematic Review and Meta-Analysis. Seattle, July.

------------------ 100. Rhee C, Chen A, You A, Kovesdy C, Brunelli S, Leung A, Brent G, Kalantar-Zadel K,

Nguyen D (2016) Thyroid functional disease, quality of life, and mental health in a prospective hemodialysis cohort. Submitted (ASN Annual Meeting, Chicago, IL, Nov 15-20, 2016)

101. Yu J, You A, Moradi H, Streja E, Zaldivar F, Haddad F, Nakata T, Kaji K, Lopez N,

Nguyen D, Kovesdy C, Kalantar-Zadel K, Rhee C (2016) The adiponectin/leptin ratio as a predictor of mortality in a prospective hemodialysis cohort. Submitted (ASN Annual Meeting, Chicago, IL, Nov 15-20, 2016)

102. You A, Kalantar-Zadel K, Nguyen D, Amin A, Streja E, Obi Y, Nakata T, Lou L, Veliz,

Gillen D, Kovesdy C, Rhee C (2016) Residual urine output and mortality in a prospective hemodialysis cohort. Submitted (ASN Annual Meeting, Chicago, IL, Nov 15-20, 2016)

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103. Rhee C, You A, Soohoo M, Streja E, Sim J, Nguyen D, Kovesdy C, Kalantar-Zadel K

(2016) Hypoglycemia-related hospitalizations and mortality among non-dialysis dependent CKD patients transitioning to dialysis. Submitted (ASN Annual Meeting, Chicago, IL, Nov 15-20, 2016)

104. Chou J, Streja E, Soohoo M, Sim J, Amin A, Nguyen D, Kovesdy C, Kalantar-Zadel K

(2016) Association of Hospitalizations pre-ESRD and Rate of Hospitalization upon Transition to Dialysis among US Veterans: A Transition of Care in CKD Study. Submitted (ASN Annual Meeting, Chicago, IL, Nov 15-20, 2016)

105. Rhee C, Kalantar-Zadel K, Ravel V, Streja E, Brunelli S, Nguyen D, Brent G, Kovesdy C

(2016) Thyroid functional disease and mortality in us veterans with chronic kidney disease. Submitted (ASN Annual Meeting, Chicago, IL, Nov 15-20, 2016)

106. Ravel V, Soohoo M, Rhee C, Streja E, Nguyen D, Kovesdy C, Kalantar-Zadel K (2016)

Association of pre-ESRD Depression with post-ESRD Mortality: A Transition to CKD Study. Submitted (ASN Annual Meeting, Chicago, IL, Nov 15-20, 2016)

107. Soohoo M, Streja E, Amin A, Mathew A, Nguyen D, Kovesdy C, Kalantar-Zadel K

(2016) Disparities in Age and the Association of Number of Hospitalizations pre-ESRD and after Dialysis Transition among US Veterans: A Transition of Care in CKD Study. Submitted (ASN Annual Meeting, Chicago, IL, Nov 15-20, 2016)

108. Soohoo M, Streja E, Sim J, Rhee C, Nguyen D, Kovesdy C, Kalantar-Zadel K (2016)

Hemoglobin Levels Prior to Transition to Dialysis and Early Dialysis Hospitalization among US Veterans: A Transition of Care in CKD Study. Submitted (ASN Annual Meeting, Chicago, IL, Nov 15-20, 2016)

109. Soohoo M, Streja E, Rhee C, Amin A, Nguyen D, Molnar M, Kovesdy C, Kalantar-Zadel

K (2016) Association of 6-month pre-ESRD Potassium with Immediate post-dialysis Hospitalization among US Veterans: A Transition of Care in CKD Study (2016) Submitted (ASN Annual Meeting, Chicago, IL, Nov 15-20, 2016)