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19630495

63

LAMPIRAN

Lampiran 1. Informed consent

JUDUL PENELITIAN : Pengaruh Pemberian Parasetamol 1000 MG

Intravena Perioperatif Terhadap Penggunaan

Fentanyl pada Pasien Kraniotomi di RSUP Dr.

Kariadi Semarang

INSTANSI PELAKSANA : Fakultas Kedokteran Universitas Diponegoro

PENELITI : Irma Amalia

Persetujuan Setelah Penjelasan

(INFORMED CONSENT)

Berikut ini naskah yang akan dibacakan pada Responden / Ibu Responden

Penelitian :

(a.I. berisi penjelasan apa yang akan dialami oleh responden diwawancarai)

Yth Bapak/Ibu :

Peneliti yang tersebut diatas adalah Mahasiswa Fakultas Kedokteran Universitas

Diponegoro yang bermaksud ingin menggunakan data rekam medik dalam

peneitian ini dengan tujuan mengetahui pengaruh pemberianm parasetamol 1000

mg intravena perioperatif terhadap penggunaan fentanyl pada pasien kraniotomi

di RSUP Dr. Kariadi Semarang. Peneliti akan mengambil data identitas,

kebutuhan fentanyl yang diperlukan selama operasi, skor visual analog scale,

serta kejadian mual muntah yang terjadi pada pasien tersebut. Peneliti menjamin

kerahasiaan identitas dan informasi yang diberikan. Informasi tersebut hanya

digunakan untuk kepentingan penelitian. Bapak/ Ibu berhak menolak dan

keluardari penelitian sesuai dengan keinginan.

Terima kasih atas kerjasama Bapak/Ibu/Sdr.

64

Setelah mendengar dan memahami penjelasan penelitian, dengan ini saya

menyatakan

SETUJU / TIDAK SETUJU

Untuk ikut sebagai responden / sampel penelitian.

Semarang,………………..... 2014

Saksi : Nama Terang :

Nama Terang : Alamat :

Alamat :

65

Lampiran 2. Ethical clearance

66

Lampiran 3. Surat ijin penelitian

67

Lampiran 4. Laporan Tindakan Anestesi

68

69

Lampiran 6. Lembar Evaluasi

70

71

Lampiran 6. Data SPSS

Crosstabs

Jenis kelamin * Kelompok Crosstabulation

7 6 13

6.5 6.5 13.0

35.0% 30.0% 32.5%

17.5% 15.0% 32.5%

13 14 27

13.5 13.5 27.0

65.0% 70.0% 67.5%

32.5% 35.0% 67.5%

20 20 40

20.0 20.0 40.0

100.0% 100.0% 100.0%

50.0% 50.0% 100.0%

Count

Expected Count

% within Kelompok

% of Total

Count

Expected Count

% within Kelompok

% of Total

Count

Expected Count

% within Kelompok

% of Total

Laki-laki

Perempuan

Jenis kelamin

Total

Kontrol Perlakuan

Kelompok

Total

Chi-Square Tests

.114b 1 .736

.000 1 1.000

.114 1 .736

1.000 .500

.111 1 .739

40

Pearson Chi-Square

Continuity Correctiona

Likelihood Ratio

Fisher's Exact Test

Linear-by-Linear

Association

N of Valid Cases

Value df

Asymp. Sig.

(2-sided)

Exact Sig.

(2-sided)

Exact Sig.

(1-sided)

Computed only for a 2x2 tablea.

0 cells (.0%) have expected count less than 5. The minimum expected count is 6.

50.

b.

72

Umur

Case Summaries

Umur

20 38.90 12.208 35.00 18 57

20 43.20 12.792 44.50 15 72

40 41.05 12.533 41.00 15 72

Kelompok

Kontrol

Perlakuan

Total

N Mean Std. Deviation Median Minimum Maximum

Tests of Normality

.156 20 .200* .924 20 .120

.113 20 .200* .980 20 .931

Kelompok

Kontrol

Perlakuan

Umur

Statistic df Sig. Statistic df Sig.

Kolmogorov-Smirnova

Shapiro-Wilk

This is a lower bound of the true significance.*.

Lilliefors Significance Correctiona.

Kelompok

PerlakuanKontrol

Um

ur

80

60

40

20

25

35

73

T-Test

Group Statistics

20 38.90 12.208 2.730

20 43.20 12.792 2.860

Kelompok

Kontrol

Perlakuan

Umur

N Mean Std. Deviation

Std. Error

Mean

Independent Samples Test

.227

.636

-1.088 -1.088

38 37.917

.284 .284

-4.300 -4.300

3.954 3.954

-12.304 -12.305

3.704 3.705

F

Sig.

Levene's Test for

Equality of Variances

t

df

Sig. (2-tailed)

Mean Difference

Std. Error Difference

Lower

Upper

95% Confidence Interval

of the Difference

t-test for Equality of

Means

Equal variances

assumed

Equal variances

not assumed

Umur

74

Lama operasi

Case Summaries

Lama operasi

20 279.00 75.457 285.00 150 420

20 300.00 97.939 300.00 165 480

40 289.50 86.948 300.00 150 480

Kelompok

Kontrol

Perlakuan

Total

N Mean Std. Deviation Median Minimum Maximum

Tests of Normality

.158 20 .200* .940 20 .236

.180 20 .089 .919 20 .095

Kelompok

Kontrol

Perlakuan

Lama operasi

Statistic df Sig. Statistic df Sig.

Kolmogorov-Smirnova

Shapiro-Wilk

This is a lower bound of the true significance.*.

Lilliefors Significance Correctiona.

Kelompok

PerlakuanKontrol

La

ma

op

era

si

500

400

300

200

100

75

T-Test

Group Statistics

20 279.00 75.457 16.873

20 300.00 97.939 21.900

Kelompok

Kontrol

Perlakuan

Lama operasi

N Mean Std. Deviation

Std. Error

Mean

Independent Samples Test

2.396

.130

-.760 -.760

38 35.679

.452 .452

-21.000 -21.000

27.646 27.646

-76.966 -77.086

34.966 35.086

F

Sig.

Levene's Test for

Equality of Variances

t

df

Sig. (2-tailed)

Mean Difference

Std. Error Difference

Lower

Upper

95% Confidence Interval

of the Difference

t-test for Equality of

Means

Equal variances

assumed

Equal variances

not assumed

Lama operasi

76

Kelompok

Case Summaries

20 20

2.50 1.90

1.051 .553

2.00 2.00

1 1

4 3

20 20

1.25 1.00

1.372 .973

1.00 1.00

0 0

4 3

40 40

1.88 1.45

1.362 .904

2.00 2.00

0 0

4 3

N

Mean

Std. Deviation

Median

Minimum

Maximum

N

Mean

Std. Deviation

Median

Minimum

Maximum

N

Mean

Std. Deviation

Median

Minimum

Maximum

Kelompok

Kontrol

Perlakuan

Total

VAS.1 VAS.24

Tests of Normality

.283 20 .000 .845 20 .004

.269 20 .001 .815 20 .001

.372 20 .000 .728 20 .000

.250 20 .002 .839 20 .003

Kelompok

Kontrol

Perlakuan

Kontrol

Perlakuan

VAS.1

VAS.24

Statistic df Sig. Statistic df Sig.

Kolmogorov-Smirnova

Shapiro-Wilk

Lilliefors Significance Correctiona.

77

VAS.1

Kelompok

PerlakuanKontrol

VA

S.1

4

3

2

1

0

VAS.24

Kelompok

PerlakuanKontrol

VA

S.2

4

3

2.5

2

1.5

1

0.5

0

11

16

1

3

4

10

78

Kontrol

NPar Tests

Wilcoxon Signed Ranks Test

Ranks

9a 6.94 62.50

3b 5.17 15.50

8c

20

Negative Ranks

Positive Ranks

Ties

Total

VAS.24 - VAS.1

N Mean Rank Sum of Ranks

VAS.24 < VAS.1a.

VAS.24 > VAS.1b.

VAS.24 = VAS.1c.

Test Statisticsb

-1.877a

.061

Z

Asymp. Sig. (2-tailed)

VAS.24 -

VAS.1

Based on positive ranks.a.

Wilcoxon Signed Ranks Testb.

79

Perlakuan

NPar Tests

Wilcoxon Signed Ranks Test

Ranks

6a 6.17 37.00

4b 4.50 18.00

10c

20

Negative Ranks

Positive Ranks

Ties

Total

VAS.24 - VAS.1

N Mean Rank Sum of Ranks

VAS.24 < VAS.1a.

VAS.24 > VAS.1b.

VAS.24 = VAS.1c.

Test Statisticsb

-1.026a

.305

Z

Asymp. Sig. (2-tailed)

VAS.24 -

VAS.1

Based on positive ranks.a.

Wilcoxon Signed Ranks Testb.

80

NPar Tests

Mann-Whitney Test

Ranks

20 25.68 513.50

20 15.33 306.50

40

20 26.15 523.00

20 14.85 297.00

40

Kelompok

Kontrol

Perlakuan

Total

Kontrol

Perlakuan

Total

VAS.1

VAS.24

N Mean Rank Sum of Ranks

Test Statisticsb

96.500 87.000

306.500 297.000

-2.906 -3.239

.004 .001

.004a

.002a

Mann-Whitney U

Wilcoxon W

Z

Asymp. Sig. (2-tailed)

Exact Sig. [2*(1-tailed

Sig.)]

VAS.1 VAS.24

Not corrected for ties.a.

Grouping Variable: Kelompokb.

81

Kelompok

Case Summaries

Delta VAS

20 -.60 1.314 .00 -3 2

20 -.25 1.020 .00 -3 1

40 -.43 1.174 .00 -3 2

Kelompok

Kontrol

Perlakuan

Total

N Mean Std. Deviation Median Minimum Maximum

Tests of Normality

.226 20 .009 .930 20 .155

.297 20 .000 .847 20 .005

Kelompok

Kontrol

Perlakuan

Delta VAS

Statistic df Sig. Statistic df Sig.

Kolmogorov-Smirnova

Shapiro-Wilk

Lilliefors Significance Correctiona.

Delta VAS

Kelompok

PerlakuanKontrol

Delt

a V

AS

2

1

0

-1

-2

-327

82

NPar Tests

Mann-Whitney Test

Ranks

20 18.78 375.50

20 22.23 444.50

40

Kelompok

Kontrol

Perlakuan

Total

Delta VAS

N Mean Rank Sum of Ranks

Test Statisticsb

165.500

375.500

-.986

.324

.355a

Mann-Whitney U

Wilcoxon W

Z

Asymp. Sig. (2-tailed)

Exact Sig. [2*(1-tailed

Sig.)]

Delta VAS

Not corrected for ties.a.

Grouping Variable: Kelompokb.

Fentanyl

Case Summaries

Fentanyl

20 201.25 67.119 200.00 100 350

20 185.00 96.108 175.00 100 400

40 193.13 82.234 200.00 100 400

Kelompok

Kontrol

Perlakuan

Total

N Mean Std. Deviation Median Minimum Maximum

Tests of Normality

.207 20 .024 .926 20 .129

.212 20 .019 .821 20 .002

Kelompok

Kontrol

Perlakuan

Fentanyl

Statistic df Sig. Statistic df Sig.

Kolmogorov-Smirnova

Shapiro-Wilk

Lilliefors Significance Correctiona.

83

Kelompok

PerlakuanKontrol

Fe

nta

ny

l400

350

300

250

200

150

100

84

NPar Tests

Mann-Whitney Test

Ranks

20 22.45 449.00

20 18.55 371.00

40

Kelompok

Kontrol

Perlakuan

Total

Fentanyl

N Mean Rank Sum of Ranks

Test Statisticsb

161.000

371.000

-1.087

.277

.301a

Mann-Whitney U

Wilcoxon W

Z

Asymp. Sig. (2-tailed)

Exact Sig. [2*(1-tailed

Sig.)]

Fentanyl

Not corrected for ties.a.

Grouping Variable: Kelompokb.

85

Mual muntah

Case Summaries

Mual muntah

20 .30 .657 .00 0 2

20 .00 .000 .00 0 0

40 .15 .483 .00 0 2

Kelompok

Kontrol

Perlakuan

Total

N Mean Std. Deviation Median Minimum Maximum

Tests of Normalityb

.476 20 .000 .515 20 .000

Kelompok

KontrolMual muntah

Statistic df Sig. Statistic df Sig.

Kolmogorov-Smirnova

Shapiro-Wilk

Lilliefors Significance Correctiona.

Mual muntah is constant when Kelompok = Perlakuan. It has been omitted.b.

Kelompok

PerlakuanKontrol

Mu

al m

un

tah

2

1.5

1

0.5

0

2

16

67

86

NPar Tests

Mann-Whitney Test

Ranks

20 22.50 450.00

20 18.50 370.00

40

Kelompok

Kontrol

Perlakuan

Total

Mual muntah

N Mean Rank Sum of Ranks

Test Statisticsb

160.000

370.000

-2.079

.038

.289a

Mann-Whitney U

Wilcoxon W

Z

Asymp. Sig. (2-tailed)

Exact Sig. [2*(1-tailed

Sig.)]

Mual muntah

Not corrected for ties.a.

Grouping Variable: Kelompokb.

87

Lampiran 7. Dokumentasi

88

Lampiran 8. Biodata mahasiswa

BIODATA MAHASISWA

Nama : Irma Amalia

NIM : 22010110120005

Tempat/tanggal lahir : Jakarta 14 Januari 1993

Jenis Kelamin : Perempuan

Alamat : Jl. Cipinang Jaya GG No. 12 C Jakarta

Nomor Telepon : 082133353592

e-mail : irmamalia@gmail.com

Riwayat Pendidikan Formal

1. SD : SD BPS&K III Lulus tahun: 2004

2. SMP : SMP N 52 Jakarta Lulus tahun: 2007

3. SMA : SMA N 54 Jakarta Lulus tahun: 2010

4. FK UNDIP : Masuk tahun: 2010