Cosmetic Compositions Having Skin Calming and Skin Regenerating Effect and Process for the...

8/10/2019 Cosmetic Compositions Having Skin Calming and Skin Regenerating Effect and Process for the Preparation Thereof

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Cosmetic compositions having skin calming and skin regenerating effectand process for the preparation thereof United States Patent 4855137The invention relates to cosmetic compositions having skin calming andregenerating effect comprising the extract of the aerial shoot and/or t !er of"er salem artichoke #$elianth s t !eros s %&' as active ingredient&

(nventors)*eri+ Ti!or #,e!recen+ $U'*ristof+ "anosne #,e!recen+ $U'-pplication . m!er)

7/ 10875P !lication ,ate)

8/ 8/1 82iling ,ate)

1/1 /1 87ie Patent (mages)

,o nload P,2 4855137 P,2 help6xport itation)

lick for a tomatic !i!liograph generation-ssignee)(nnofinance+ -ltalanos (nnovacios Pen9inte9et #: dapest+ $U'Primar lass)404/4 1(nternational lasses) A61K8/97 ; A61Q19/00 ; A61K8/96 ; - 1*35/782ield of Search)404/1 5&1edical :otan + p& 08&Primar 6xaminer)=ollins+ "ohn ?&-ttorne + -gent or 2irm), !no+ $er!ert> ers+ "onathan

laims)?e claim)

1& - cosmetic composition having a skin@calming and skin@regenerating effectcomprising as active ingredient+ an aA eo s or alcoholic extract of the aerialshoot+ t !er+ or aerial shoot and t !er of a "er salem artichoke in an amo nt of
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1& to 5 B together ith a pharmace ticall accepta!le topical inert carrier ordil ent&

0& The cosmetic composition having a skin@calming and skin@regeneratingeffect defined in claim 1 f rther comprising a ater@!inding agent&

3& The cosmetic composition having a skin@calming and skin@regeneratingeffect defined in claim 1 f rther comprising a vitamin&

4& The cosmetic composition having a skin@calming and skin@regeneratingeffect defined in claim 1 f rther comprising a disinfectant&

5& The cosmetic composition having a skin@calming and skin@regeneratingeffect defined in claim 1 f rther comprising an anti!acterial agent&

& The cosmetic composition having a skin@calming and skin@regeneratig effectdefined in claim 1 comprising as active ingredient a mixt re of the extracts ofthe aerial shoot and t !er of the "er salem artichoke herein the vol me ratioof the extract of the aerial shoot to that of the t !er is !et een &5)1& and0& )0 & &

7& - process for the preparation of a cosmetic composition having a skin@calming and skin@regenerating effect hich comprises the steps of)

#a' cleaning and cr shing aerial shoots of "er salem artichoke;

#!' extracting the cleaned and cr shed aerial shoots of "er salem artichoke itha 1 to 1 fold amo nt of ater+ ethanol+ or a mixt re of ater and ethanol+ at atemperat re !et een room temperat re and the !oiling point of the mixt re for10 to 1 8 ho rs;

#c' cooling the extract;

#d' filtering the extract to o!tain a filtrate; and

#e' com!ining the filtrate ith a pharmace ticall accepta!le inert carrier ordil ent&

8& - process for the preparation of a cosmetic composition having a skin@calming and skin@regenerating effect hich comprises the steps of)


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#a' ashing and slicing a t !er of "er salem artichoke;

#!' extracting the ashed and sliced "er salem artichoke ith ater;

#c' filtering the extract formed d ring step #!' to o!tain a filtrate;

#d' !oiling the filtrate for &5 to 1 ho rs;

#e' filtering the !oiled filtrate to o!tain a second filtrate; and

#f' com!ining the second filtrate ith a pharmace ticall accepta!le inertcarrier or dil ent&

& - method of treating the skin of a s scepti!le s !Cect to impart a velvet andsmooth text re thereto+ said method comprising the step of appl ing to the skina cosmetic composition containing an effective amo nt of an aA eo s oralcoholic extract of the aerial shoot or t !er of the "er salem artichoke in a

pl ralit of applications&

1 & The method defined in claim herein said extract is a mixt re of anextract of said aerial shoot ith an extract of said t !er&

,escription)

2(6%,


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parts of the c ltivated plants #$U@PS .os& 178+78 and 17 +88 + ,


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-ccording to the invention extracts are prepared from the aerial shoot and/ort !er of "er salem artichoke and the extracts ere sed separatel or incom!ination as active ingredients of cosmetic compositions& , ring o rexperiments it has !een fo nd that the extract of the aerial shoot and the s r p

prepared from the t !er as ell as their com!ination are remarka!l s ita!le for calming and regenerating tired skin and for treating certain inflammatorconditions&

The favora!le effects of the compositions of the invention ere examined inthe follo ing a &

The face tonic #6xample 7' as examined on 5 omen aged from 0 to 3ears& (t as applied after thoro gh cleaning t ice dail + in the morning and in

the evening& The treatment as contin ed for t o eeks& The follo ing t pesof the face skin ere examined) 4 slightl dr + 1 sensitive dr skins& Thetonic has !een a!sor!ed ell d ring each treatment+ the skin !ecame smooth+velvet & , ring the treatment no allergic reaction+ irritative dermatitis orh persensitivit ere o!served&

The !od lotion #6xample 5' as tested on 00 omen aged from 1 to 70ears& The lotion as applied after thoro gh ashing t ice dail + in the

morning and in the evening& The treatment as contin ed for t o eeks& Thefollo ing t pes of skin ere examined) 0 normal sensitive+ 4 dr sensitive+ 8dr and 8 normal skins& The composition has !een a!sor!ed ell d ring eachtreatment+ the skin !ecame velvet + smooth+ the skin tightening and dr ness

hich occ rred after ashing #having a !ath or sho er !ath' stopped and theskin as calmed and refreshed& .o allergic reaction+ irritative dermatitis orh persensitivit ere o!served&

The extract of the aerial shoots and the s r p prepared from the t !er can !emixed ith the s al cosmetic vehicles and dil ents as ell as ith otherkno n active ingredients e&g& anti!iotics+ disinfectants+ for example propolisand there! sta!le compositions are formed&

The compositions are prepared in the follo ing a )

#a' the cleaned and cr shed aerial shoot of "er salem artichoke is extracted itha 1 to 1 @fold amo nt of ater and/or alcohol at a temperat re !et een roomtemperat re and the !oiling point of the mixt re for from 10 to 1 8 ho rs+ thenthe mixt re is cooled and filtered+ the filtrate #solid s !stance content isgenerall a!o t from &0 to & B' is mixed ith the s al cosmetic vehiclesand/or dil ents+ prefera!l ith nat ral fats+ oils+ axes+ alcohols+ em lsif ing


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agents+ perf me s !stances and optionall ith other kno n additives+ prefera!l ater !inding agents+ disinfectants and anti!acterial agents and theconsistence of the composition th s o!tained is adC sted ith distilled aterand/or alcohol or

#!' the ashed and sliced t !er of "er salem artichoke is extracted ith ater+the extract is filtered+ the filtrate is !oiled for from &5 to 1 ho rs+ the sol tionth s o!tained is filtered+ the filtrate is mixed ith the s al cosmetic vehiclesand/or dil ents+ prefera!l ith nat ral fats+ oils+ axes+ alcohols+ em lsif ingagents+ perf me s !stances+ and optionall ith other kno n additives+

prefera!l ater !inding agents+ vitamins and anti!acterial agents and theconsistence of the composition th s o!tained is adC sted ith distilled ater&

(f desired the extracts prepared according to the processes #a' and #!' are mixedin a vol me ratio !et een &5)1& and 0& )0 & and the com!ination is sed asactive ingredient in cosmetic compositions&

The follo ing non@limiting 6xamples sho the composition of the inventionand the preparation of the active ingredient&

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Preparation of an aA eo s extract from the aerial shoots of "er salem artichoke

1 kg of the cleaned and ashed aerial shoot of "er salem artichoke is stirred for

8 ho rs in 1 litres of ater at F & Then the mixt re is filtered and thefiltrate is stored nder cooling+ protected from light and air&

6E->P%6 0

Preparation of an alcoholic extract from the aerial shoot of "er salem artichoke

1 kg of cleaned and ashed aerial shoot of "er salem artichoke is allo ed tostand for 4 da s in 4 litres of 7 B aA eo s ethanol& The mixt re is stirredseveral times dail + then after 4 da s it is filtered and the filtrate is stored nder

cooling+ protected from light and air&

6E->P%6 3

Preparation of an extract @ s r p @ from the t !er of "er salem artichoke


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1 kg of the ashed and sliced t !er of "er salem artichoke is extracted ith 1litres of ater for 10 ho rs and the extract is filtered& To the filtrate 05 ml ofacetic acid are added and the sol tion is !oiled for 3 min tes& Then it isallo ed to cool+ filtered and stored nder cooling&

6E->P%6 4

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG ream

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG

omponents

6xtract of 6xample 1 05& g

et l alcohol 3&5 g

aseline oil #cosmetic A alit '

8& g

Prop lene gl col 5& g

:=(" "01 3&5 g

6thanol # B' 4& g .ipagine &0 g

Stearic acid 4& g

,istilled ater 4 &8 g


6E->P%6 5

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG :od lotion


omponents


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P%6



omponent


6xtract of 6xample 3 3&5 g

et l alcohol 1& g

:=(" "0 0&3 g


8& g

6thanol # B' & g

.ipagine &0 g

(soprop l palmitate & g


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,istilled ater 50& g


6E->P%6 7



omponents

6xtract of 6xample 0 05&5 g


6r throm cin !ase 0& g

et l alcohol 1&5 g


7&5 g

6thanol # B' 4&5 g

.ipagine &0 g


,istilled ater 4 &8 g


6E->P%6 8

GGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGG 2ace tonic


omponents


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T een 0 &5 g

6thanol # B' 4&3 g

Perf me oil &0 g


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