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Transcript of Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc. Chapter 2 Application of...
Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Chapter 2
Application of Pharmacology in Nursing Practice
2Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Why Should a Student Nurse Learn About Drugs?
Motivation for studying Pharmacology Essential for nursing practice Worthwhile investment Much more required than the Six Rights
Right drug, patient, dose, route, time, documentation
3Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Evolution of Nursing Responsibilities Regarding Drugs Correct administration, without additional
interventions, cannot ensure that treatment will result in the therapeutic objective.
Proper delivery is only the beginning of a nurse’s responsibility.
4Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Evolution of Nursing Responsibilities Regarding Drugs Nurses + physicians + pharmacists
participate in a system of checks and balances designed to promote beneficial effects and to minimize harm.
5Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Evolution of Nursing Responsibilities Regarding Drugs The nurse must know
What medications are appropriate for the patient What drugs are contraindicated for the patient The probable consequences of the interaction
between drug and patient
6Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Evolution of Nursing Responsibilities Regarding Drugs The nurse’s role as advocate
Follows the patient’s status most closely Detect mistakes made by pharmacists and
prescribers First member of the health care team to observe
and evaluate drug responses and intervene if required
Must know the response that a medication is likely to elicit
7Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Evolution of Nursing Responsibilities Regarding Drugs The nurse’s role as advocate
Last line of defense for the patient Ethically and legally unacceptable to administer a
drug that is harmful to the patient—even though the medication has been prescribed by a licensed prescriber and dispensed by a licensed pharmacist
8Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Application of Pharmacology in Patient Care
Two major areas in which pharmacologic knowledge can be applied:1. Patient care2. Patient education
9Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Application of Pharmacology in Patient Care
1. Preadministration assessment2. Dosage and administration3. Evaluating and promoting therapeutic effects4. Minimizing adverse effects5. Minimizing adverse interactions6. Making PRN decisions7. Managing toxicity
10Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Preadministration Assessment
Collecting baseline data Needed to evaluate therapeutic responses and
adverse effects Identifying high-risk patients
Liver and kidney impairment Genetic factors Drug allergies Pregnancy Elderly and pediatric Tools: patient history, physical examination, and
laboratory results
11Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Dosage and Administration
Certain drugs have more than one indication. Dosage may differ depending on which
indication the drug is used for. Many drugs can be administered by more
than one route. Dosage may differ depending on the route
selected. Certain IV agents can cause severe local
injury if IV extravasates.
12Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Dosage and Administration
Read the medication order carefully. Verify the identity of the patient. Read the medication label carefully. Verify dosage calculations. Implement any special handling the drug may
require. Don’t administer any drug if you don’t
understand the reason for its use.
13Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Evaluating and Promoting Therapeutic Effects
Evaluating therapeutic responses: One of the most important aspects of drug therapy Must know the rationale for treatment and the
nature and time course of the intended response Cannot effectively evaluate a drug with multiple
applications if the intended use is not known
14Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Evaluating and Promoting Therapeutic Effects
Promoting patient adherence Also known as compliance or concordance Extent to which a patient’s behavior coincides with
medical advice Implementing nondrug measures
Drug therapy can often be enhanced by nondrug measures.
Biofeedback, emotional support, weight reduction, smoking cessation, sodium restriction, etc.
15Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Minimizing Adverse Effects
All drugs have the potential to produce undesired effects.
Always know the following: The major adverse effects the drug can produce The time when these reactions are likely to occur Early signs that an adverse reaction is developing Interventions that can minimize discomfort and
harm
16Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Minimizing Adverse Interactions
Take a thorough drug history. Advise the patient to avoid OTC drugs that
can interact with the prescribed medication. Monitor for adverse interactions known to
occur. Be alert for as-yet unknown interactions.
17Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Making PRN Decisions
PRN: pro re nata, meaning “as needed” Nurse has discretion regarding how much
drug to give and when to give it. Know the reason for drug use. Be able to assess the patient’s medication
needs.
18Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Managing Toxicity
Early identification makes early intervention possible.
Know the early signs of toxicity. Know the procedure for toxicity management.
19Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Application of Pharmacology in Patient Education
Drug name and therapeutic category Dosage size Dosing schedule Route and technique of administration Expected therapeutic response and when it
should develop Nondrug measures to enhance therapeutic
responses
20Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Application of Pharmacology in Patient Education
Duration of treatment Method of drug storage Symptoms of major adverse effects and
measures to minimize discomfort and harm Major adverse drug-drug and drug-food
interactions Whom to contact in the event of therapeutic
failure, severe adverse reactions, or severe adverse interactions
21Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Teaching Dosage and Administration
Give patient the following information: Name of drug Dosage and schedule of administration Technique of administration Duration of drug use Storage of drug
22Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Application of Pharmacology in Patient Education
Promoting therapeutic effects Nature and time course of expected beneficial
effects Recognizing treatment failure, allow for timely
alternative therapy implementation Minimizing adverse effects
Insulin overdose Anticancer and infection Some side effects are benign but disturbing,
especially if unknown to the patient.
23Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Minimizing Adverse Interactions
Educate patient about hazardous drug-drug and drug-food interactions. Example: phenelzine and amphetamines or figs
24Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Application of the Nursing Process in Drug Therapy
Application of the nursing process conceptual framework in drug therapy
Use of a modified nursing process format to summarize nursing implications in this text
25Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Review of the Nursing Process
Assessment Analysis: nursing diagnoses Planning Implementation (intervention) Evaluation
26Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Applying the Nursing Process in Drug Therapy
Preadministration assessment Analysis and nursing diagnoses Planning Implementation Evaluation
27Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Preadministration Assessment
Collection of baseline data to evaluate therapeutic effects
Collection of baseline data to evaluate adverse effects
Identification of high-risk patients Assessment of the patient’s capacity for
self-care
28Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Analysis and Nursing Diagnoses
Three objectives: Judge the appropriateness of the prescribed
regimen. Identify potential health problems that
the drug might cause. Determine the patient’s capacity for
self-care.
29Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Planning
Defining goals Setting priorities Identifying specific interventions
Drug administration Interventions to enhance therapeutic effects Interventions to minimize adverse effects Patient education
Establishing objective criteria for evaluation
30Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Implementation
Drug administration Patient education Interventions to promote therapeutic effects Interventions to minimize adverse effects
31Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Evaluation
Therapeutic responses Adverse drug reactions and interactions Adherence to the prescribed regimen Satisfaction with treatment
32Copyright © 2013, 2010 by Saunders, an imprint of Elsevier Inc.
Modified Nursing Process Format to Summarize Nursing Implications (see Table 2-2)
Preadministration assessment Implementation: administration Implementation: measures to enhance
therapeutic effects Ongoing evaluation and interventions Patient education What about diagnosis and planning?