ChemInform Abstract: A Versatile Catalyst for Intermolecular Direct Arylation of Indoles with...
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ChemInform 2010, 41, issue 42 © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim www.cheminform.wiley-vch.de Indole derivatives R 0140 DOI: 10.1002/chin.201042105 A Versatile Catalyst for Intermolecular Direct Arylation of Indoles with Benzoic Acids as Arylating Reagents. — A novel catalyst system consisting of palladium tri- fluoroacetate, silver nitrate and propionic acid efficiently catalyzes the regioselective arylation of N-acyl indole derivatives (I) and (VII) with benzoic acids. The reaction proceeds with both electron-rich and electron-deficient benzoic acids, but the regiose- lectivity is reversed depending on the electronic properties of the benzoic acid. — (ZHOU, J.; HU, P.; ZHANG, M.; HUANG, S.; WANG, M.; SU*, W.; Chem. Eur. J. 16 (2010) 20, 5876-5881, DOI:10.1002/chem.201000529 ; State Key Lab. Struct. Chem., Fujian Inst. Res. Struct. Matter, Chin. Acad. Sci., Fujian, Fuzhou 350002, Peop. Rep. China; Eng.) — Mischke 42- 105
Transcript of ChemInform Abstract: A Versatile Catalyst for Intermolecular Direct Arylation of Indoles with...
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Indole derivativesR 0140 DOI: 10.1002/chin.201042105
A Versatile Catalyst for Intermolecular Direct Arylation of Indoles with Benzoic Acids as Arylating Reagents. — A novel catalyst system consisting of palladium tri-fluoroacetate, silver nitrate and propionic acid efficiently catalyzes the regioselective arylation of N-acyl indole derivatives (I) and (VII) with benzoic acids. The reaction proceeds with both electron-rich and electron-deficient benzoic acids, but the regiose-lectivity is reversed depending on the electronic properties of the benzoic acid. — (ZHOU, J.; HU, P.; ZHANG, M.; HUANG, S.; WANG, M.; SU*, W.; Chem. Eur. J. 16 (2010) 20, 5876-5881, DOI:10.1002/chem.201000529 ; State Key Lab. Struct. Chem., Fujian Inst. Res. Struct. Matter, Chin. Acad. Sci., Fujian, Fuzhou 350002, Peop. Rep. China; Eng.) — Mischke
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ChemInform 2010, 41, issue 42 © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim
