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Chapter i: Introduction 2014 A NNUAL D ATA R EPORT V OLUME 2: E ND -S TAGE R ENAL D ISEASE

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2Vol 2, ESRD, Ch i vol 2 Table i.1 Summary statistics on reported ESRD therapy in the United States, by age, race, ethnicity, sex, & primary diagnosis, 2012 Incidence a December 31 point prevalenceKidney transplants Count%Adj. rate b Count% Adj. rate b Dialysis c %Tx c % Deceased donor Living donor ESRD deaths d 0-19 e 1,1631.013.17,5451.283.12,0600.55,4852.954935084 20-4413,16211.5122.2101,99416.0938.059,04513.142,94923.12,9181,9253,929 45-6445,06939.3570.2283,02144.43,550.1188,57141.894,45050.75,8512,54926,555 65-7427,93324.31,270.1140,23822.06,301.8106,10123.534,13718.31,92869624,563 75+27,48623.91,618.4104,10716.36,261.194,82521.09,2825.02477633,507 Unknown age.......... 4221 White76,08966.3279.2383,53460.21,431.8252,05355.9131,48170.66,8924,45059,868 Black/African American31,39827.3908.0200,79731.55,670.5164,21136.436,58619.63,54771823,868 Native American1,2731.1411.58,1541.32,599.56,3101.41,8441.0135411,012 Asian5,8405.1378.935,8785.62,271.825,2305.610,6485.78093523,400 Other500.0 5,8600.9 2,5150.63,3451.875*490 Unknown1630.1 2,6820.4 2830.12,3991.37748. Hispanic17,02414.8501.3106,30816.72,931.979,35217.626,95614.51,95680411,433 Non-Hispanic97,78985.2340.5530,59783.31,857.8371,25082.4159,34785.59,5794,81377,205 Male65,84257.3446.0363,49757.12,396.7252,52656.0110,97159.66,9733,48349,939 Female48,97142.7278.0273,31242.91,558.4198,00643.975,30640.44,5202,11338,696 Unknown gender... 960.0. 700.0260.04221* Data Source: Reference tables: A, B, D, E &H. a Incident counts: include all known ESRD patients, regardless of any incomplete data on patient characteristics and of U.S. residency status; b Includes only residents of the 50 states and Washington D.C. Rates are adjusted for age, race, and/or sex using the estimated 2011 U.S. resident population as the standard population. All rates are per million population. Rates by age are adjusted for race and sex. Rates by sex are adjusted for race and age. Rates by race are adjusted for age and sex. Rates by disease group and total adjusted rates are adjusted for age, sex, and race. Adjusted rates do not include patients with other or unknown race. c Patients are classified as receiving dialysis or having a functioning transplant. Those whose treatment modality on December 31 is unknown are assumed to be receiving dialysis. Includes all Medicare and non-Medicare ESRD patients, and patients in the U.S. territories and foreign countries. d Deaths are not counted for patients whose age is unknown. e Age is computed at the start of therapy for incidence, on December 31 for point prevalence, at the time of transplant for transplants, and on the date of death for death.. Zero values in this cell. Abbreviations: Adj., adjusted; ESRD, end-stage renal disease; Tx, transplant.

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Vol 2, ESRD, Ch i3 vol 2 Table i.1 Summary statistics on reported ESRD therapy in the United States, by age, race, ethnicity, sex, & primary diagnosis, 2012 (continued) Incidence a December 31 point prevalenceKidney transplants Count%Adj. rate b Count% Adj. rate b Dialysis c %Tx c % Deceased donor Living donor ESRD deaths d Diabetes50,53444.0154.3239,83737.7731.0197,07943.742,75823.03,3551,08140,795 Hypertension32,61028.4101.1159,04925.0489.4129,09228.629,95716.12,50583324,975 Glomerulonephritis9,1157.928.3106,01216.6325.852,84111.753,17128.52,5491,6796,828 Cystic kidney disease2,5302.27.929,8814.792.411,5262.618,3559.98326201,548 Urologic disease5380.51.67,4471.222.93,5760.83,8712.113391589 Other known cause12,28110.738.259,7149.4184.737,4588.322,25611.91,3567839,935 Unknown cause3,5063.110.825,9774.178.215,8833.510,0945.44232163,101 Missing cause3,6993.210.68,9881.418.13,1470.75,8413.1382314867 All114,813100.0353.2636,905100.01,942.9450602 f 100.0186,303100.011,5355,61788,638 Unadjusted rate g 358.6 1,968.2 Total transplants h 17,330 Data Source: Reference tables: A, B, D, E &H. a Incident counts: include all known ESRD patients, regardless of any incomplete data on patient characteristics and of U.S. residency status; b Includes only residents of the 50 states and Washington D.C. Rates are adjusted for age, race, and/or sex using the estimated 2011 U.S. resident population as the standard population. All rates are per million population. Rates by age are adjusted for race and sex. Rates by sex are adjusted for race and age. Rates by race are adjusted for age and sex. Rates by disease group and total adjusted rates are adjusted for age, sex, and race. Adjusted rates do not include patients with other or unknown race. c Patients are classified as receiving dialysis or having a functioning transplant. Those whose treatment modality on December 31 is unknown are assumed to be receiving dialysis. Includes all Medicare and non-Medicare ESRD patients, and patients in the U.S. territories and foreign countries. d Deaths are not counted for patients whose age is unknown. f Includes patients whose modality is unknown. g Unadjusted total rates include all ESRD patients in the 50 states and Washington D.C. h Total transplants as known to the USRDS * Values for cells with ten or fewer patients are suppressed.. Zero values in this cell. Abbreviations: Adj., adjusted; ESRD, end-stage renal disease; Tx, transplant.

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Vol 2, ESRD, Ch i4 vol 2 Figure i.1 Counts of new & returning dialysis patients, 19912012 (a) New patients Data Source: CMS Form 2744, Annual Facility Survey. Patients restarting dialysis (Panel B) are those who had temporarily recovered kidney function, had discontinued dialysis or had been lost to follow-up but restarted routine dialysis during the survey period. (b) Patients restarting dialysis

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Vol 2, ESRD, Ch i5 vol 2 Figure i.1 Counts of new & returning dialysis patients, 19912012 (continued) Data Source: CMS Form 2744, Annual Facility Survey (c) Patients returning from transplant(d) Total patients starting /restarting

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Vol 2, ESRD, Ch i6 vol 2 Table i.2 ESRD-certified patients on the waiting list for kidney and kidney/pancreas transplants New listings in 2012N (as of 12/31/2012) Median time on list (years) a 0-176335640.30 18-448,19520,5473.19 45-6415,33645,1593.55 65-744,27114,0883.76 75+4321,6234.98 Unknown... Male17,75049,2303.21 Female11,11732,7513.53 White17,53744,2482.61 African American8,89529,9874.14 Native American3649964.49 Asian1,8436,0065.21 Other2287444.59 Unknown... Hispanic5,41316,0804.49 Non-Hispanic23,45465,9013.15 Data source: Reference Table E. a patients listed for a kidney-alone transplant during 2007.* cells with ten or fewer patients are suppressed..zero patients in this cell. Abbreviations: ESRD, end-stage renal disease.

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Vol 2, ESRD, Ch i7 vol 2 Table i.2 ESRD-certified patients on the waiting list for kidney and kidney/pancreas transplants (continued) New listings in 2012N (as of 12/31/2012) Median time on list (years) a Diabetes10,32328,2404.47 Hypertension6,38519,7643.56 Glomerulonephritis6,06118,3312.46 Cystic kidney disease 1,5154,5821.92 Urologic disease2738502.47 Other known cause2,9647,0261.33 Unknown cause8772,7292.36 Missing cause469459. A9,31722,9642.23 B4,22413,3754.20 AB1,1272,2671.36 O14,19943,3754.18 PRA