Central Nervous System Histology Slide Orientation

Spinal cord

Dorsal horns: InterneuronsVentral horns: Motor neurons Lateral horns: Sympathetic neurons Parasympathetic (S2-4) neuronsDRG: Sensory (pseudounipolar) neuronsAutonomic ganglia: Post ganglionic neurons with unmyelinated axons. Sympathetic: paravertebral ganglia Parasympathetic: In organs

65-2 Lumbar Spinal Cord, H&E

D.R.G.

Spinal Cord

Dura mater

Myelinated nerves

#65-1N Spinal cord and DRG

Ventral horn

Lateral horn

Dorsal horn

Dorsal root ganglion (DRG)

66a Thoracic Spinal Cord

Ventral median fissure

Dorsal horn

Lateral horn

Ventral horn

Dorsal median sulcus

Dorsal nucleus of

Clarke(proprioceptive

)

66a Thoracic Spinal Cord

Neurons in Lateral Horn

Neurons in ventral Horn

65-1N Motor neurons, glial cells and neuropil

Glial cells

Neuropil

Dorsal root ganglion cells

#74 Sympathetic ganglion cells #75 Parasympathetic ganglion cells

Seminal vesicle

Sensory and Autonomic Neurons (DRG) (Parasympathetic)

Cerebrum

Sulcus (sulci) Gyrus (gyri)

Cerebellum

Pons Medulla oblongata

3rd ventricle

4th ventricle

Brain

Cerebrum and Cerebellum

76b

77

#77 Cerebellum #76b Cerebrum

W WW

CC

C

W

C: Cortex of gray matter W: White

matter

#77 Cerebellum

Cortex

White matter

#77 Cerebellum

WM

GL

ML

Purkinje neurons (cells)

#77a Cerebellar Cortex

#76 Cerebrum

Wh

ite m

atte

rW

hite

matte

r

CORTEX OF GRAY MATTER

#76

Ross and Pawlina, p.311

Cereb

ral cortex

Cerebellum Cerebrum

CC

W

W

Purkinje cells (neurons)

Pyramidal cells (neurons)

C: Cortex of gray matter W: White matter

Hippocampal Formation

Lateral View Posterior View

LIMBIC LOBE (Cortical Areas) Cortex Type

Cingulate gyrus & Isthmus Neocortex (six layers)

Subcallosal area

Parahippocampal Gyrus Paleocortex (3-5 layers)

Uncus

Hippocampus Archicortex (3 layers)

(Deep within parahippocampal gyrus)

Hippocampal Formation Dentate GyrusHippocampus

Subiculum

Martin: NeuroanatomyFigs. 15-3, 4, 14

#NP004N Hippocampal regionCA: Cornus ammonis

CA1

CA3

CA2

Dentate gyrusHippocamp

us

Choroid plexus

Subiculum

Lateral ventricl

e

Fornix

3 layers of Dentate gyrusArchicortex (3 layers), as opposed to Neocortex (6 layers)

Mol

ecul

ar

laye

r

Granule cell layer (neurons)

Polymorphic layer Polymorphic layer (interneurons)

Molecular layer (dendrites of granule cells)

3 layers of Hippocampus(Archicortex)

Molecular

layer

Pyramidal cell layer

Polymorphic layer

Pyramidal cells