CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT...

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CEA CHRU CNRS CPU INRA INRIA INSERM INSTITUT PASTEUR IRD ARIIS EFS INERIS INSTITUT CURIEINSTITUT MINES-TELECOM UNICANCER IRBA IRSN CIRAD FONDATION MERIEUX 1 ITMO Genetics, genomics & bioinformatics The impact of genetics, genomics & bioinformatics on personalized medicine Thierry Grange, CNRS CEA CHRU CNRS CPU INRA INRIA INSERM INSTITUT PASTEUR IRD ARIIS EFS INERIS INSTITUT CURIEINSTITUT MINES-TELECOM UNICANCER IRBA IRSN CIRAD FONDATION MERIEUX

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Transcript of CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT...

Page 1: CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX 1 ITMO Genetics,

CEA

CHRU CNRS CPU INRA INRIA INSERM INSTITUT PASTEUR IRDARIIS EFS INERIS INSTITUT CURIE INSTITUT MINES-TELECOM UNICANCERIRBA IRSNCIRAD

FONDATION MERIEUX

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ITMO Genetics, genomics& bioinformatics

The impact of genetics, genomics & bioinformatics on personalized

medicineThierry Grange, CNRS

CEA

CHRU CNRS CPU INRA INRIA INSERM INSTITUT PASTEUR IRDARIIS EFS INERIS INSTITUT CURIE INSTITUT MINES-TELECOM UNICANCERIRBA IRSNCIRAD

FONDATION MERIEUX

Page 2: CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX 1 ITMO Genetics,

CEA

CHRU CNRS CPU INRA INRIA INSERM INSTITUT PASTEUR IRDARIIS EFS INERIS INSTITUT CURIE INSTITUT MINES-TELECOM UNICANCERIRBA IRSNCIRAD

FONDATION MERIEUX

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ITMO Genetics, genomics& bioinformatics

Coordination of the action of the French research institutions in

Genetics, Genomics & Bioinformatics

CEA

CHRU CNRS CPU INRA INRIA INSERM INSTITUT PASTEUR IRDARIIS EFS INERIS INSTITUT CURIE INSTITUT MINES-TELECOM UNICANCERIRBA IRSNCIRAD

FONDATION MERIEUX

Page 3: CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX 1 ITMO Genetics,

CEA

CHRU CNRS CPU INRA INRIA INSERM INSTITUT PASTEUR IRDARIIS EFS INERIS INSTITUT CURIE INSTITUT MINES-TELECOM UNICANCERIRBA IRSNCIRAD

FONDATION MERIEUX

Major strategic priorities

• Next Generation Sequencing & Bioinformatics: Integrating Big Data with Modeling

• Epigenetics & Regulation of Gene Expression: Interactions between genomes and environment

• Evolution of genomes and populations• Individual genomes and personalized

medicine

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Page 4: CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX 1 ITMO Genetics,

CEA

CHRU CNRS CPU INRA INRIA INSERM INSTITUT PASTEUR IRDARIIS EFS INERIS INSTITUT CURIE INSTITUT MINES-TELECOM UNICANCERIRBA IRSNCIRAD

FONDATION MERIEUX

Key transversal question

• Understanding the relationship between genotype and phenotype

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Page 5: CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX 1 ITMO Genetics,

CEA

CHRU CNRS CPU INRA INRIA INSERM INSTITUT PASTEUR IRDARIIS EFS INERIS INSTITUT CURIE INSTITUT MINES-TELECOM UNICANCERIRBA IRSNCIRAD

FONDATION MERIEUX

5

ITMO Genetics, genomics& bioinformatics

How genetics, genomics and bioinformatics can contribute to

personalized medicine?

CEA

CHRU CNRS CPU INRA INRIA INSERM INSTITUT PASTEUR IRDARIIS EFS INERIS INSTITUT CURIE INSTITUT MINES-TELECOM UNICANCERIRBA IRSNCIRAD

FONDATION MERIEUX

Page 6: CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX 1 ITMO Genetics,

CEA

CHRU CNRS CPU INRA INRIA INSERM INSTITUT PASTEUR IRDARIIS EFS INERIS INSTITUT CURIE INSTITUT MINES-TELECOM UNICANCERIRBA IRSNCIRAD

FONDATION MERIEUX

Interpreting personal genomes

• Sequencing personal genomes is becoming technically and financially within reach

• How can this information be used to adapt treatments to the individual genetic make-up?

• There is a need to better understand the relationship between genome sequences and personal/population phenotypes

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CEA

CHRU CNRS CPU INRA INRIA INSERM INSTITUT PASTEUR IRDARIIS EFS INERIS INSTITUT CURIE INSTITUT MINES-TELECOM UNICANCERIRBA IRSNCIRAD

FONDATION MERIEUX

Today’s speakers

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Thierry Frebourg, InsermCHU Rouen

Lluis Quintana-Murci, CNRSInstitut Pasteur


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CEACHRUCNRSCPUINRAINRIAINSERMINSTITUT PASTEURIRD ARIISEFSINERISINSTITUT CURIEINSTITUT MINES-TELECOMUNICANCERIRBAIRSNCIRADFONDATION MERIEUX 1 ITMO Génétique,

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