Case 7a &b, 8
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Transcript of Case 7a &b, 8
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Case 7a
Smear for interpretation
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Case 7a
1. Leukemic Infiltration2. NHL- T cell Lymphoma3. Lymphoma/Leukemic Infiltration4. Adult T cell Lymphoma
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DIAGNOSIS
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LYMPHOMA/LEUKEMIC INFILTRATION
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Case 7b
53y/M, presented with altered sensorium
CSF cytology
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Case 7b
1. Seizary Syndrome2. Mets- Duct Ca breast/AML – M73. AML – M5/M74. Mets – NHL, Anaplastic5. AML,HCL6. Hematolymphoid Malignancy7. Multiple Myeloma
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53y/M, Endoscopic biopsy – Adenoca, signet ring type, Gr III with H/O distal gastrectomy(HPE 7492/13 ) – Adenocarcinoma Gr-III
L V emboli +, 7/16 LNs mets.+ , Extranodal spread +
Post – Op. CT given
Now presenting with CNS symptoms
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DIAGNOSIS
Carcinomatous Meningitis
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Case 8
17y/F presented with h/o
hemiparesis, altered sensorium.
CSF Cytology
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DIAGNOSIS
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Case 8
1. 1. Cryptococcal Meningitis2. Myeloid Precursors – S/o Leukemoid reaction3. Positive - ? ALL, ? AML4. AML with CNS Involvement5. ?ALL , ?Lymphoma6. AML – M77. Viral Encephelitis
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Reactive Lymphoid Cells
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Detection of Leukemic Lymphoblasts in CSFIs Instrument-DependentAlison R. Huppmann, MD,1Susan R.Rheingold,MD,2L. Charles Bailey, MD,2 Marybeth Helfrich,BSMT, ASCP,1 and John K. Choi, MD, PhD1,3
Wescor Cytopro showed a 5- to 9-fold increasein the number of cells retrieved compared withthe equivalent slide from the Shandon CytoSpin
Am J Clin Pathol 2012;137:795-799
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