CAMPO RESEARCH PTE LTD€¦ · Label Skin-Whitening Soap manufacture for International and Regional...

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CAMPO RESEARCH PTE LTD

Level 30, 6 Battery Road, Singapore 049909

Tel: (65) 63833203 / 202 / 63833631 Direct Fax (65) 63833632 / 63834034

Email: [email protected]

Website: http///www.campo-research.com Internet-Video-Phone Teleconferencing: [email protected]

For Technical Assistance

CAMPO® Multi-Purpose Cosmetic Base Chemicals & Active Ingredients

CAMPO® Novel Functional Active Cosmetic Ingredient & Raw Materials

Campo Songyi Skin Whitening Fairness Bath Soaps

CAMPO CD VERSION 3.7.2 dated 23 November 2013 © 2013 Library of Congress Wash.DC 2

Skin-whitening soaps are for more than a half century were produced as Anti-Septic Soaps with ingredients like ammoniated mercury,

potassium mercuric iodide, and other toxic mercuric compounds,carboxylic, and its hydroquinone derivatives. These whitening soaps were household trend consumables and were estimated that more that US$ 100 billion worth of these whitening (aka: antiseptic) soaps were sold in African continent alone in the past 50 years.

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In the early Fifties (1950s) when the knowledge of ochronosis (Deposition &accumulation of dark brown pigment in bone cartilage, bone-joint capsules and other tissues, usually resulted of alkaptonuria) Alkaptonuria is congenital absence (in off-springs of) in users of mecuric, carboxylic, phenol hydroquinone based whitening/antiseptic soaps) of homogentisic acid oxidase, an enzyme that breaks down tyrosine and phenylalanine.

Accumulation of homogentisic acid in homozygotes causes brown pigmentation of skin and eyes and damage to joints & other organs, urine blackens on standing; were known based on extensive medical studies on the prevalent epidemical medical conditions of whitening /antiseptic soap users. The large multi-nationals then (by 1960s) discontinued the uses of mercuric, carboxylic and phenol hydroquinone in their branded soaps, but the smaller soap manufacturers (mainly East Indian firms) in these countries grabbed the opportunity of the market vacuum-created to supply The still existing excessive demand, which saw the introduction of “Robert Brand”,”Bukilsal” and ”Robert Medicated” antiseptic soap which main purposes are for skin-whitening effect; emerged as Intra-Africa national soap brands.



A toxic mercuric antiseptic family soap brand "crystal white" {from Robert’s Group) Circa 1950s.

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1997, the last country in Africa, Nigeria to banned the manufacture, importation, and use of these soap brands and the use of mercuric compounds, phenols and hydroquinone in any soap manufactures. While EEC too implemented the ban on importation of these type antiseptic /whitening soaps for its African ethnic populations. The regulatory requirements of INCI names listing of the ingredients in Soap packaging, finally end the deadly saga of more than half a century of countless untold and mostly known but uneliminatable source for human sufferings that is transmitted by congenital defects to users' off-springs and afflicted directly on the users themselves. With an estimated $20 billion market in Africa alone and $15 billion for Far-east Asia in per

Annum terms, the search for the safe non-toxic Skin-Whitening active begins! The Soul Search of the ever expanding whitening products market for Natural Non-Toxic Alternative Skin-Whitening Actives: Begins!

Castille soaps containing 100% Olive Oil and 0.005% Songyi Mushroom

Ceramide Oil Extract for skin whitening. The Far-east Asia's long-time used Matsutake mushroom oil for traditional skin whitening lotions, ointments and skin-whitening soaps in Japan and known as Songyi mushroom oil in Korea, Taiwan and China were the natural candidates and alternatives for new whitening active ingredients in whitening soaps and this mushroom oil was re-discovered and incorporated into the antiseptic soaps and skin-whitening toiletry soaps, since 1994.



Castille Whitening Soap with Songyi Mushroom Gel oil and olive oil

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A Skin-whitening Soap is a cosmetic under FDA 21 CFR Cosmetic Act and is regulated

as a cosmetic under Section 201(i) of the Act because of labeling claims as a Skin-

Whitening Soap and the packaging requires full ingredient disclosure statement in

accordance with the requirements of 21 CFR 701.3. The INCI NAME(S) Songyi Mushroom Gel Oil :TTrriicchhoolloommaa mmaattssuuttaakkee

SSiinnggeerr EExxttrraacctt ((aanndd)) CCeerraammiiddee 33 ((aanndd)) GGllyycceerriinn

Songyi Mushroom Gel Ceramide Oil Extract: Tricholoma matsutake Singer Extract (And) Ceramide 3 (and) Water

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Songyi mushroom Gel oil or Songyi mushroom Gel Ceramide Oil Extract based Skin-whitening Soap bar or Liquid Soap is to be applied on skin-patch in volunteers' arms as repeat insult patch test assays, at 6 number of times, for 30 days and observed for irritancy.

RRReeesssuuullltttsss::: none (non-irritation)

“Eyetex” Assay, & “Ames” Assay, Results available. WWWhhhiiittteeennniiinnnggg eeeffffffeeecccttt:::

Lathers of Songyi mushroom Gel oil & Songyi Mushroom Ceramide Oil Extr. 0.50% each respectively based soap is applied on volunteers' forearm for a duration of overnight, and later within 24 hours observed with a Woods lamp (UV light). A comparison test of hydroquinone, and kojic acid 99% concentrated solution can be applied on the other arm. RRReeesssuuullltttsss:::

Songyi mushroom Gel oil & Songyi Mushroom Ceramide Oil Extr. 0.5%

each respectively based Soap's lather gives visible greater whitening effect in comparison with 99% conc. Of Hydroquinones or Kojic acid under Woods lamp within 24 hours. Clinical manifestation of whitening effect will be pronounced by the 7 days of use (once a day with 3 minute lathering over required face or body parts) or 3 days (2x a day with 3 minute lathering over required face or body parts).



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Refined from natural Songyi Mushroom (Korean) and Matsutake mushroom (Japanese) from the Japan, this Songyi based skin-whitening soap bar is highly active with functional properties of effective young skin clarifying and novel non-irritant skin-whitening functions, with outstanding results in counteracting darkening of the skin by the sun and inflamed hyper-pigmentation. Songyi Soap bars is also effective in providing a fading lightening effect on the brown spotting of chloasma and is effectively useful to stop the spreading of aging skin freckles. With a natural and mild formula, it can

be used with all types of skin, and upon regular use, Consumers will discover to their surprise in the course of time that their skin complexion has turned a clear lighten complexion.

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These soap bars are produced by a modern biotechnology process from a special variety of natural deep-sea seaweed cited in the ancient "Chinese Traditional Compendium of Materia Medica" for its prominent ability to reduce and reverse the sagging aging skin into a rejunventated tight young skin. “Lowering the 12 kinds of skin swelling, and treating cellulite

accumulation beneath the skin (TCM)”. At the same time, it causes no irritation to the skin, and although the surface is rough, as soon as you begin using it, you will feel its smooth, lubricating qualities. When used regularly, its action assists in stimulating the metabolism, reducing fat cellulite and softening the skin. SSSKKKIIINNN---WWWHHHIIITTTEEENNNIIINNNGGG AAANNNTTTIII---CCCEEELLLLLLUUULLLAAATTTEEE SSSOOOAAAPPP IIINNN BBBAAALLLLLLSSS SSSHHHAAAPPPEEE



SSSKKKIIINNN WWWHHHIIITTTEEENNNIIINNNGGG AAANNNTTTIII---CCCEEELLLLLLUUULLLIIITTTEEE SSSOOOAAAPPP

This is an improved formula soap of THE SKIN WHITENING ANTI-CELLULITE SOAP, in which the proportion of the deep-sea seaweed extract and Songyi Ceramide Oil - two of the ingredients has been boosted to yield higher weight reducing, skin softening and whitening effects. TTTHHHEEE SSSKKKIIINNN WWWHHHIIITTTEEENNNIIINNNGGG AAANNNTTTIII---CCCEEELLLLLLUUULLLAAATTTEEE SSSOOOAAAPPP &&& LLLIIIQQQUUUIIIDDD SSSOOOAAAPPP

EEEXXXTTTRRRAAA WWWHHHIIITTTEEENNNIIINNNGGG---FFFAAACCCIIIAAALLL SSSOOOAAAPPP

This contains a special refined natural Songyi Ceramide Oil -the Songyi Mushroom's Essence), with functional highly effective brightening Qualities with the functions of clearing and fading away darken spots and caring for the skin with replacement human-identical skin ceramides. It causes no irritation to the face, and sustained use can enrich and soften the skin, making it clear, lighten and bright. Natural Skin Ceramides losses, which cause skin aging, can be replaced by the Songyi ceramides for rejuvenation of young skin conditions.

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Contains Neem oil, Songyi Mushroom Gel Ceramide Oil Extract and Songyi Gel Liquid and special Campo fruit and vegetable enzymes, with extra-healing properties of clearing up acne and caring for the skin, it can make the skin rich and moist and spotlessly clean and clear complexion.



HHHEEERRRBBBAAALLL NNNIIIAAAGGGAAARRRAAA SSSOOOAAAPPP FFFOOORRR AAADDDUUULLLTTTSSS Containing the quintessential cells of natural Trichopus zealanicus Fruits, roots, Leaves extracts (Herbal Viagara), pilose antler, Songyi mushroom Ceramide oil and Gingko biloba flavones, refined by biotechnology to preserve its functionality’s of substantive pore penetration, awakening the skin with zest feeling, strengthening the body, increasing potency and eliminating fatigue, this product is indeed a favorite of adult males.

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Campo Research currently arrange Songyi mushroom oil based Private-Label Skin-Whitening Soap manufacture for International and Regional

Clients, via soap Contract -manufacturers in Turkey, South Korea, China, Taiwan, UK, USA, France, Greece and Italy. The skin-whitening soaps are available as Soap bars or as liquid soap or as syndet powders or as body shampoos or as facial cleanser.



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MMMOOORRREEE OOOFFF TTTHHHEEE WWWHHHIIITTTEEENNNIIINNNGGG SSSKKKIIINNN CCCAAARRREEE SSSYYYSSSTTTEEEMMMSSS ELEGANT SKIN CARE SYSTEM: Derma Rx Exclusive Whitening Beauty Kit

BRAND ITEM: Les Regenerateur Derma Rx with your Private Label

AS SEEN OF TV PRODUCT TYPE: Skin Care System (Beauty Kit)

PACKAGED: Retail ready

DESCRIPTION OF KIT SIZE: 1' x 11/2’ x 4” Elegant White Box With Private Label Logo Embossed TheBox.



Each product is packaged separately in an elegant white shipping container. Each of the five products is placed in an elegant white

shipping box with Five pockets to cradle each product. Each kit contains one of each of the following:

Day Whitening Gel: 2 oz. of very high quality Gel.

Night Brightening Cream: oz. jar of very high quality cream.

Eye Gel spheres: ½ oz.glass bottle with a gold pump and cap.

Skin-Whitening Radiant Body Lotion: 6 ounce Bottle with a vacuum

pump.



Click on Icon to link Click on Icon to Link (Internet log

•Effective Functional Dose in Skin Whitening Bath Soaps: Songyi Mushroom Gel oil > 0.003- >0.005 %

•Songyi Mush. Gel Ceramide Oil Extract:>0.0003- >0.005 %

Add Songyi gel(s) at the Mixer



Product Data and Technical Specifications

•Campo Songyi Gel Oil for Skin-Whitening Soaps •Other Name:Matsutake Gel Oil

•INCI Name: Tricholoma matsutake Singer Extract (and) Ceramide 3 (and) Glycerin

•Product# : 98-18-04-01 Oleo-Sol

•Species :Tricholoma matsutake Singer

•Parts Used :Whole Mushroom-Freezed Dried

•Appearance :Golden Yellow Flowing Oily Liquid

•Odor :Characteristic faint

•Specific Gravity (20 deg.C): 1.020 - 1.370

•Refractive Index (20 deg.C): 1.250 -1.450

•Solvent(s): Carbon dioxide gas

•Carrier menstrual (vehicle):vegetable Ceramide oil 5%; glycerin

50%

•Preservative: None

•Anti-oxidants: None

•Total Germs,(WHO standard): < 100 cfu/ml Non-pathogenic

•Total Yeast / Molds: < 100 cfu

•Heavy Metals(total) Pb, As, Hg: < 0.005 PPM Comments: Dissolve about >0.003% for skin-whitening bath soaps or

Up to 15% to the oil phase of the formulation for Skin-Whitening Cremes and Lotions. Shake

Well the Songyi Gel Oil containing Drum(s) before addition to Soap Mixer or Formulation Mixer

This material is not available on ex-stock basis and prior contractual purchase arrangement is

required at least 6 months before the first shipment

Product Data and Technical Specifications



•Campo Songyi Mush.Gel Ceramide Oil Extract for Skin-Whitening Products

•Other Name:Matsutake Gel Ceramide Oil Extract

•INCI Name: Tricholoma matsutake Singer Extract (and) Ceramide 3 (and) Water

•Product# 98-19-09-1 Ceramide Extr.

•Species: Tricholoma matsutake Singer

•Parts Used: Whole Mushroom-Freezed Dried

•Appearance: Yellowish Brown Viscous Flowing Liquid

•Odor: Characteristic faint

•Specific Gravity (20 deg.C): 1.010 - 1.4700

•Refractive Index (20 deg.C): 1.250 -1.450

•Solvent(s): Carbon dioxide gas

•Carrier menstrual (vehicle): Amphilic Ceramide oil 50%; Water

25%

•Preservative: None

•Anti-oxidants: None

•Total Germs,(WHO standard): < 100 cfu/ml Non-pathogenic

•Total Yeast / Molds: < Nil

•Heavy Metals(total) Pb, As, Hg:< 0.005 ppm

•Comments: Dissolve about >0.003% ->0.05 % for skin-whitening bath soaps or Up to 10% to the formulation for Skin-Whitening Cremes and Lotions Shake Well the Songyi Gel Ceramide Oil Extract containing Drum(s) before addition to Soap Mixer or Formulation Mixer



MATERIAL SAFETY DATA SHEETS

CONFIRMS TO EC DIRECTIVE 91/155/EEC, EC REGULATION

NO#1272/2008, AMENDED EC REGULATION NO#790/2009 and

Complies toThe EU Cosmetic Products Regulation (Regulation (EC)

No 1223/2009) effective on July 2013., AND to US DEPT.OF

LABOR-Occupational Safety & Health Admin directives and

compliant to Globally Harmonized System of Classification and

Labeling of Chemicals (hereinafter referred to as “the GHS”).

http://www.osha.gov/dsg/hazcom/ghs.html

http://www.unece.org/trans/danger/publi/ghs/ghs_welcome_e.html

http://www.hc-sc.gc.ca/ahc-asc/intactiv/ghs-sgh/index-eng.php

DATE OF FIRST ISSUE

DATE OF LATEST REVISION

February 10th 1993-Reviewer:

Dr. Balasubramaniam Ph. D

December 20th 1996 Reviewer:

Dr. Fergus Jes Velasquez, BSc. Med.

Tech., MD

Februrary 5th

2013 – Reviewer –

Dr Balasubramaniam M, PhD 1 IDENTIFICATION

COMMERCIAL NAME:

OTHER TRADE NAME:

LATIN NAME:

INCI NAME: (Proposed)

(EC REGULATION NO#1272/2008

AMENDED NO#790/2009) and Compliant to

the GHS.

EPA (USA) GENERIC NAME:

MANUFACTURER :

(cGMP MFG. FACILITIES) :

EMERGENCY TELEPHONE NUMBERS:

CAMPO SONGYI GEL CERAMIDE

OIL EXTRACT for Skin-Whitening Bath

Soaps & Whitening Products

Matsutake Gel Ceramide Oil Extract

Tricholoma matsutake Singer

Tricholoma matsutake Singer extract

(and) Ceramide 3 (and) Water

Vegetable Extract

CAMPO RESEARCH Pte Ltd

Level 30, 6 Battery Road,

Singapore 049909. Or at Kampoyaki

Research Sdn Bhd. Taman Perindustrian

Perms Jaya; Permas Jaya, Masai Johor;

Malaysia

(65)-63833631/(65)-63833203

(Singapore)

2 COMPOSITION

100 PERCENT CARBON-DIOXIDE GAS

EXTRACTED TRICHOLOMA MATSUTAKE

MYCELIUM/ PLANT PARTS COMPONENTS

EXTRACTED IN CERAMIDE OIL AND

DEIONISED WATER CARRIER MENSTRUM

CAS NO# (EC REGULATION NO#1272/2008


the GHS

EINECS#

Tricholoma

matsutake

(S) extract Water

Ceramide Oil

N/A 7732-18-5

100403-19-8

N/A 231-791-2

309-560-3



EINECS NAME (EC REGULATION NO#1272/2008


the GHS

RISK PHRASES

SAFETY PHRASES 25-26

Tricholoma Water-distilled

Ceramide

matsutake (S) Extr./

Vegetable Extract

None

Not Mandatory

GHS CLASSIFICATION :

This material is Non-hazardous according to

UN-GHS Criteria.

PICTOGRAM : NONE

GHS LABEL ELEMENTS: No GHS Pictogram (Totally Non-

Hazardous Division 1.6; No Hazard

Statement.

3

NOT CLASSIFIED AS DANGEROUS

ACCORDING TO DIRECTIVE 67/548/EEC,



the GHS

DIVISION 1.6; NON-HAZARDOUS

NO HAZARD STATEMENT

HAZARD CLASS and CATEGORY

CODE(s)

HAZARD STATEMENT CODE(s)



the GHS

PICTOGRAM : NONE

No GHS Pictogram (Totally Non-


Statement.

GHS CLASSIFICATION :

This material is Non-hazardous according to

UN-GHS Criteria.

PICTOGRAM : NONE



Statement.

GHS LABEL ELEMENTS:



Statement.

4 FIRST AID MEASURES

EYE CONTACT:

ORAL INGESTATION:

SKIN CONTACT:

Wash with water or standard eye wash

solution. Seek medical advice, if

irritation occur and persist.

Essentially non-toxic and edible in small

quantity ( 5 gms) with bland to bitter

sweet ethanolic after taste.

Wash with water or shower.

5 FIRE FIGHTING MEASURERS

NON-COMBUSTIBLE AND PRESENTS NO

SPECIAL FIRE HAZARDS.

EXTINGUISHING MEDIA:

PROTECTIVE EQUIPMENTS FOR FIRE

FIGHTERS:

Treat as oil fire when store in HDPE

drums with CO2, dry foam or dry

chemical.

Standard Equipments.

6 ACCIDENTAL RELEASE MEASURES

ABSORB ONTO AN INERT MATERIAL AND

SCRAPE UP. REMOVE RESIDUE BY

SCRUBBING WITH HOT WATER OR

DETERGENT SOLUTION.



7 HANDLING AND STORAGE

STORE IN SEALED CONTAINERS UNDER

NORMAL COOL, DRY WAREHOUSING

CONDITIONS.

8 EXPOSURE AND PERSONAL PROTECTION

IN ACCORDANCE WITH GOOD

INDUSTRIAL PRACTICE AND HANDLING

USING STANDARD EYE PROTECTION.

9 PHYSICAL AND CHEMICAL PROPERTIES

PHYSICAL FORM:

COLOUR:

ODOUR:

BOILING POINT:

MELTING POINT:

VISCOSITY:

RESIDUE ( 160 deg.C Mettler )

FLASH POINT:

FLAMMABILITY SOLID/GAS:

AUTO FLAMMABILITY:

SPECIFIC REFRACTIVE:

EXPLOSIVE PROPERTIES:

PH:

OXIDIZING PROPERTIES:

VAPOUR PRESSURE:

DENSITY:

WATER SOLUBILITY:

OTHER SOLUBILITY:

BULK DENSITY:

PARTITION COEFFICIENT:

(OCTANOL/WATER)

EXPLOSIVE LIMITS:

Viscous slow flowing liquid paste

Yellowish brown

Characteristic faint

110.6C.

-

50 -150 cps

>45%

195 deg. cent.

N/A

N/A

1.250 – 1.450

N/A

N/A

N/A

N/A

1.020-1.4700

Completely Cloudy brown Soluble at 5-

25 % concentration

Glycerine , Propylene Glycol, Water,

Ethanol

-

-

-

-

-

10 STABILITY AND REACTIVITY

THERMAL DECOMPOSITION:

Stable under normal conditions of use.

11 TOXICOLOGICAL DATA Animal Tests Last Done 1992, as requirements of EC DIRECTIVE 91/155/EEC

ORAL:

DERMAL:

INHALATION:

LD50 > 23,000 MG/KG (Body Wt.) Rat

Essentially Non-Toxic and Edible in

Small Quantity.

Expected To Be Essentially Non Toxic.

Slight Ethanolic Sting - irritation

SPECIFIC CONCENTRATION LIMITS

M-FACTORS



the GHS.

23,000MG/KG (Body Wt.);

CATEGORY 5

Essentially Non-Toxic and Edible in

Small Quantity.

TOXIC EFFECTS:

SKIN:

Primarily Irritation Index (PII) = 0.0 (

Non- Irritating - Skintex ), Not A

Primarily Irritant.

Non-irritant / Non-sensitizer as per

Repeated Patch Insult Test on 50 Human

volunteers.

Human Repeated Patch Test 48 hours:

50/50 completely non-irritating / non-



EYE: erythema causing ingredient at 10%

concentrate in water on 50 human

volunteers

Very Mild/Minimal - Not A Transient

Conjunctival Irritant at 10% concentrate

in water (Eyetex - Eyetex classification ).

Summarized toxicological data as shown

here are formation bounded under Non-

Disclosure Agreement with various

clients as when these Toxicological Data

were established or their exclusive uses.

12 ECOLOGICAL INFORMATION

BIODEGRATION:

FISH TOXICITY:

BACTERIAL & VIRAL TOXICITY:

WGK CLASS:

Expected To Be Ultimately

Biodegradable.

No Data

Not harmful to bacterial and viral

microorganisms.

WGK (Self Classification)

13 DISPOSAL CONDITIONS

DISPOSE OFF ACCORDING TO A

RECOGNISED METHOD OF CHEMICAL

WASTE DISPOSAL.

14 TRANSPORT INFORMATION

UN NUMBER# :

UN NAME:

IMDG CODE/CLASS:

IMDG CODE PAGE NO.

ICAO/IATA AIR CLASS:

ICAO/IATA AIR CLASS PACKING GROUP:

RID/ADR CLASS:

ADNR CLASS:

N/A

Not Assigned

Not Hazardous

N/A

Non-Hazardous

N/A

Non-Hazardous

Non-Hazardous

LABELLING:



the GHS.

PICTOGRAM SIGNAL WORD CODE(s):

HAZARD STATEMENT CODE(s):

SUPPLEMENTARY HAZARD

STATEMENT CODE(s):

No GHS Pictograms (Totally Non-

Hazardous)

Division 1.6; No Hazard Statement

Similar Division 1.6; No Hazard

Statement

15 REGULATORY INFORMATION

OCCUPATIONAL EXPOSURE LIMITS: N/A

16 OTHER INFORMATION

USES AS A COSMETIC ADDITIVE

Shake The Drums Well Before Use SUPPLEMENTARY DIETARY/FOOD USE. Campo JTC Phippines Ltd /Kampoyaki Research Sdn Bhd

(Malaysia)

>0.003% to >5.0 % or more as

required

Shake The Drums Well Before Use N/A



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CAMPO RESEARCH PTE LTD€¦ · Label Skin-Whitening Soap manufacture for International and Regional...

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Transcript of CAMPO RESEARCH PTE LTD€¦ · Label Skin-Whitening Soap manufacture for International and Regional...