BMedSc Bachelor of Medical Science Year 1 Curriculum Please set your programme to show “bookmarks”. By clicking on the bookmarks you can navigate to each separate module in the first year of the course. In addition to a description of the module, you will also find a list of the teaching sessions in the module. This will help you to gain detailed information about the Medical Science course. The modules that you take in the first term are:

Introduction to Research in biomedical Science Introduction to Biomedical Science 1 Cellular Processes Neuroscience 1 Molecules and Movement Employability Skills Passport (Level C)

In the second term you will take:

Introduction to Biomedical Science 2 Cardiovascular and Respiratory System Digestive System 1 Pharmacology Infection 1 Employability Skills Passport (Level C)

Please note that all modules in the first year are compulsory. Because of this, all second year modules can assume prior knowledge and take you to a deeper level of understanding in each subject area. Most modules are assessed by in-course assessments (25%) and end of year examinations (75%).

BMedSc Bachelor of Medical Science Year 1 Modules: Introduction to Research in Biomedical Science Module Description This module introduces the curriculum and indicates the responsibilities of students and staff to effective learning and assessment. Sources of printed and electronic information will be identified along with methods of retrieval from library archives. Computer instruction will familiarise students with skills required for presentation of course work and includes word processing, spreadsheets, essay and research project structure and composition, interview techniques. The module links to continuous assessments in Cellular Processes and Introduction to Biomedical Science I and II. The mathematical principles underpinning the biological basis of the various modules will be introduced in a graded manner to accommodate different student abilities. The core elements of scientific enquiry and data analysis will be introduced during the module culminating in a student-led mini research project. Module Content

Session Session Title

Lecture Intro to BMedSc Course

Lecture Introduction to the Module and the Employability Skills Passport

Lecture Intro to Library Skills

Lecture Introduction from Head of Student Development and Support

ComPrac Introduction to using the library

ComPrac Word Processing, Spreadsheets and Powerpoint

SGT Thinking critically

Lecture Expressing yourself in writing

Lecture Managing Stress

AnatPrac Introduction to anatomy

Lecture STEM

ComPrac Literature searching and Internet

SGT Written and Oral Communication 1

SDL Numeracy self test & "Solutions and Dilutions"

Lecture Basics of experimental design

SGT Numeracy - SOD

Lecture Interpretation of experimental data

SDL Maths problems

Lecture Sort Out Difficulties with Maths Problems

SGT Writing a report

Exam Practice Maths Test

SGT Data handling problems

Lecture Review and Intergration

Exam Assessed Maths Test

SGT Skills 8

SGT Skills 9

Lecture Self Learning: project write up

Lecture Data Handling and Spreadsheet analysis

Lecture Research Seminar

Lecture Sort Out Difficulties

SGT Skills 10

SGT Assessed Maths Test

Learning Outcomes By the end of the module the student should be able to:

1. Understand the elements required for the structure, content and presentation of written work

2. Appreciate the main features of oral presentation 3. Demonstrate competence in the use of word processing, spreadsheet and

PowerPoint 4. Access databases and use the world wide web and email. Understand the

dynamics of interviews. 5. Understand the mathematical basis of biomedical science 6. Familiarisation with experimental design, data recording, interpretation and

communication

Assessment The module is assessed by coursework only

Completion of in class worksheets 10% Mathematical problems 90% (10% for semester 1, 60% for semester 2, 20% (mini project)

Hours 38hrs (8hr lectures; 1 careers session; 1hr library session; 1 Anatomy SGT + 10hr core SGT; 5hr computer practical, 2hr “Sort out difficulties” session (optional attendance); 4hr self-directed learning sessions; 1 research seminar (external speaker); 3hr tests (1formative, 2 summative)

BMedSc Bachelor of Medical Science Year 1 Modules: Introduction to Biomedical Science 1

Module Description This is the first of two linked modules spanning the first year of the course. Introduction to Biomedical Science 1 gives an introduction to the biochemical composition of the cell, the organisation of cells and tissues and basic processes involved with energy metabolism.

Module Content

Session Session Title

Lecture Introduction to the Module

Lecture Structure and Replication of DNA

Lecture Structure and properties of RNA

Lecture Regulation of Gene Expression 1

Lecture Amino Acids and Proteins

Lecture Regulation of Gene Expression II

Lecture Enzymes

SDL Case Study 1

Lecture Biological Membranes

SGT Proteins and Diseases

Lecture Membrane Transport

SDL Case Study 2

Lecture Cellular Processes I

Lecture Cellular Processes Il

Tutorial Assessment Tutorial

Lecture Fluid Compartments I

LabPrac Core Labskills 1

Lecture Fluid Compartments II

AnatPrac Introduction to Histology and classification of Tissues

LabPrac Core Labskills 2

SGT Fluid Compartments

AnatPrac Prep of Visualisation of Histological Specimens

Lecture Glucose Metabolism

AnatPrac Epithelial Tissue

SGT Fluid Compartments

LabPrac Core LabSkills 3

SGT Metabolism I

AnatPrac Topography and Histology of the Skin

SGT Metabolism II

AnatPrac Histology and Histopathology of connective tissue

Anat Prac Histology of Cartilage and Bone

SGT Assessement Feedback

AnatPrac Histology Test

Learning Outcomes Demonstrate a basic knowledge and understanding of:

1. The synthesis, biological properties and functions of the macromolecules from which cells are made

2. The internal structures of the cell and the basic functions which they perform 3. The organisation and functions of the cell surface 4. The characteristics of basic tissues and cell types and the functions they perform 5. Basic histological techniques and the ability to identify components within

histological sections.

6. The cell's energy currency and of the importance of catabolism and anabolism Demonstrate an ability to:

1. Produce a written scientific communication

Assessment The module is assessed by a combination of written examination (25 MCQ, 4 short notes & 1 essay question) and course work.

Examination 75% (Semester 2) Course work 25% (Semester 1) The course work component will include the following:

Essay 15% Histology test 5% MCQ test 5% (taken in January) Linked modules Introduction to Biomedical Science 2 Hours 36 Hours (17hr lectures; 2hr seminar; 10hr tutorials; 7hr practical)

BMedSc Bachelor of Medical Science Year 1 Modules: Cellular Processes

Module Description The structural and energetic bases of cellular reactions are introduced together with some of the experimental methods used to study molecular properties and defective function. Specific examples of cellular processes, from enzyme catalysis to signalling systems, link the module to Molecules and Movement, Neuroscience and to Digestive System.

Module Content

Session Session Title

Lecture Bimolecular processes

Lecture Water and pH in cellular processes

Lecture Ionisation and buffering in cellular processes

Lecture Data analysis review

ComPrac From numbers to function

Lecture Basis for Biomolecular Structure

Lecture Defective Folding as Basis for Disease + SLA

Lecture Protein interactions

ComPrac Binding equilibria

SGT Macromolecular Structure

Lecture Catalysis and Enzyme Activity

Lecture Exploring disease biomarkers

SGT Ionisation in Solution + SOD

ComPrac Exploring cellular reactions + SLA

Lecture Purification of Proteins

Lecture Biological Spectroscopy 1

LabPrac Protein separation methods

Lecture Protein characterisation approaches

Lecture Biological Spectroscopy 2

SGT Spectroscopy in Practice + SOD

ComPrac Practical MCQ & Enzyme regulation SLA

Lecture Cooperativity and allostery

Lecture Cellular Communication

LabPrac ATP Synthesis

ComPrac Experimental design & practical review

ComPrac ATP synthesis practical - MCQ

SGT Review of Cellular Processes + SOD

Lecture Energetics of Cellular Processes

ComPrac Exam: Data Handling Test

Learning Outcomes By the end of the module the student will have a basic knowledge, understanding and an:

1. Awareness and fundamental understanding of the structural and energetic bases for the molecular mechanisms of cellular reactions;

2. Appreciation of techniques used in the study of biomolecules and biochemical reactions;

3. Development of observational, manipulative and deductive skills through practicals, cluster sessions and data-handling classes

Assessment The module is assessed by a combination of a written examination (25 MCQ, 4 short notes and 1 essay question) and course work. Examination 75% (Semester 2) Course work 25% (Semester 1) The course work component will include the following: 2 Practical comprehension MCQ tests 10% 1 Data handling test 10% MCQ test 5% (taken in January) Hours 35 Hours (17hr Lectures, 4 x 1hr Computer Cluster sessions; 2x3hr practicals; 4 x 1-2hr data handling classes. Voluntary remedial data handling and feedback/surgery sessions (3 x 1hr). Two (1hr) timetabled student-led activity sessions.

BMedSc Bachelor of Medical Science Year 1 Modules: Neuroscience 1

Module Description This is the first of a series of systems and/or subject based course elements in Years 1 and 2. It considers the structure and function of nerves and synapses in general and then goes on to cover in greater detail the structure and function of the sensory, autonomic and enteric nervous systems. It is linked to the following modules: Cardiovascular and Respiratory Science 1, Digestive System 1 and Pharmacology. These links reflect a) the integration between the physiological control of the cardiovascular and digestive system with the nervous system and b) the importance of the peripheral nerves and synapses as drug targets. Module Content

Session Session Title

Lecture Introduction to the Module

Lecture Membranes and Cell Excitation

Lecture The Basis of Excitability

Lecture Neurones, Synapses, Role of Transmitters

ComPrac Sensory Receptors PBL A

ComPrac Introduction to Neurones in Action

SGT Action Potentials

Lecture The Neuromuscular Junction

ComPrac Introduction to Neurones in Action

ComPrac Sensory Receptors PBL B

ComPrac Neurones in Action: The Na+ Action Potential

AnatPrac Histol and Histopath of Nervous System 1 and 2

Lecture Somatic Nervous System: an Overview

Lecture Nerve and Muscle: Degeneration and Re-innervation

SGT Nerve Function and Dysfunction

Prac Nerve Action Potentials

AnatPrac Topography of Brain, Spinal Cord and Cranial Nerves

AnatPrac Topography of the Sensory Systems

ComPrac Neuroscience Assessment 1

Lecture Chemical Senses

Lecture Sensory System: Vision

Lecture Sensory System: Somatosensory

Lecture Sensory System: Audition

Prac Auditory Function

Lecture Simple Reflexes

Lecture Anatomy of the Autonomic Nervous System: an Overview

Tutorial Sensory Systems

Lecture Functioning of the Autonomic Nervous System: an Overview

Lecture The Enteric Nervous System

ComPrac Neuroscience Assessment 2

Learning Outcomes By the end of the module the student will be able to:

1. Appreciate the topographical organisation of the nervous system; in particular, the sensory division of the somatic, the enteric and autonomic nervous systems. Also, be familiar with the distribution and function of the cranial nerves.

2. Understand the principles by which neurons are able to: receive and recognise information from the internal and external environments; to generate electrical signals; to communicate with other cells via synapses (including the multisynaptic pathways of simple reflexes).

3. Demonstrate an awareness of the structure and function of the organs involved in the special senses of sight and hearing and chemical senses.

4. Be aware of the principles involved in forming the nervous system during embryonic development

5. Be able to follow instructions to carry out quantitative experiments and be able to present and interpret the data

Assessment The module is assessed by a combination of a written examination (25 MCQ, 4 short notes & 1 essay question) and course work.

Examination 75% (Semester 2) Course work 25% (Semester 1)

The course work component will include the following:

Practical write up with questions 15% Web-based MCQ tests 5% MCQ test 5% (taken in January)

Hours 37.5 Hours (16 hr lecture; 9 hr tutorial; 12.5 hr practical).

BMedSc Bachelor of Medical Science Year 1 Modules: Molecules & Movement

Module Description Review of motility processes from the cellular level to those of higher animals. The molecular aspects of different muscle and non-muscle motile mechanisms are compared and a cross-system consideration of the involvement of molecular motors in cellular activity is described. The module content links to Introduction to Biomedical Sciences I, Biochemistry, Neuroscience, Digestive System, and Cardiovascular & Respiratory System (all Level 1 Modules).

Module Content

Session Session Title

Lecture Introduction: How Cells Move

AnatPrac Histology and Histopathology of Muscle tissues

Lecture Bacterial Motility and Chemotaxis

Lecture Actin: Introduction

Lecture Actin Polymerisation

Lecture Actin-binding Proteins 1

Lecture Actin-binding Proteins 2

Lecture Integration of Cellular Mobile Activity

Lecture Molecular Motors 1 - Myosins

SGT Non-Muscle Motility

Lecture Neuromuscular Transmission

Lecture Skeletal Muscle

Lecture Mechanics of Contraction

Lecture Biochemistry of Contraction

Prac Skeletal Muscle Contraction

Lecture Cardiac Muscle

Lecture Microtubules & Intermediate filaments

Lecture Smooth Muscle

Lecture Stable microtubule assemblies & Molecular motors 2 – Kinesin

SGT Striated Muscle Contraction

Lecture Cytoskeleton and Disease

SGT Microtubules & motors

Learning Outcomes By the end of the module the student will have:

1. An awareness of the variety of cellular motility systems in eukaryotes and prokaryotes;

2. An appreciation of the mechanism of action of different molecular motors and the disease basis for dysfunction;

3. Developed observational, manipulative and deductive skills though practical classes;

Assessment The module is assessed by a combination of a written examinations (4 short notes and 2 essay questions) and course work (MCQ, practical, and essay).

Examination 75% (Semester 2) Course work 25% (Semester 1)

The course work component includes the following:

Practical write up 10% Essay (1500 words) 10% MCQ test 5% (taken in January)

Hours 27 Hours (19x 1hr lectures, 3x 1hr tutorials, 1x 2hr practical/demonstration, 1x 3hr practical)

BMedSc Bachelor of Medical Science Year 1 component: Employability Skills passport (Level C) non credit-bearing

Component Description The purpose of this component is to encourage students to develop a number of skills which are critical for their on-going development on the course but also for their future employability prospects. To achieve this goal, the component will focus on the non-module specific skills acquired during the year. This will not require any additional assessment but emphasises and rewards engagement of students with these elements. Furthermore, it ensures that students are not progressing with deficiencies in their skills which could put them at a significant disadvantage in subsequent years.

Students shall normally be required to:

1. Attend, engage with and contribute to all identified compulsory teaching sessions, including anatomy7, laboratory and computer practicals, small group teaching sessions, tutorials and progress tutorials.

2. Engage with their Personal Tutor during Progress Tutorials and reflect on the subject and transferable/employability skills that they are developing with the aid of feedback that they have received.

Component Outcomes By the end of the component students should be able to:

1. Demonstrate a basic level of ability to contribute to communicate orally and in writing scientific concepts and/or data

2. Undertake laboratory work safely and competently, to the level taught at level C 3. Demonstrate a willingness to work effectively in groups and contribute to the

achievement of common goals 4. Demonstrate a willingness to engage in reflective practice relating to their

learning experiences

BMedSc Bachelor of Medical Science Year 1 Modules: Introduction to Biomedical Science 2

Module Description This is the second of two linked modules spanning the first year of the course. Introduction to Biomedical Science 2 gives an introduction to control of cell numbers, basic genetics, human embryology, molecular biology, recombinant DNA and aspects of human genetics and disease. Module Content

Session Session Title

Lecture Fertilisation and Pre-implantation Development

Lecture Implantation and the Placenta

Lecture Establishing the Primary Body Map

Lecture Ectoderm and nervous system development

Lecture Mesoderm: somitogenesis, muscle and bone

Lecture Mesoderm: urogenital system development

Lecture Cell Proliferation 1

Lecture Cell Proliferation 2

Lecture Endoderm and its derivatives

Lecture Cell Proliferation 3

Lecture Recombinant DNA & Cloning

Lecture Experimental Technology I: DNA and RNA

Lecture Experimental Technology 2: RNA

Lecture Experimental Technology 3; Antibodies as experimental tools

Tutorial Assessment Tutorial

SGT Problem Based Session

LabPrac Molecular Biology Techniques

Lecture Mendelian Genetics – dominance and recessiveness

Lecture Mendelian Genetics- X-linked inheritance

Lecture Origin of genetic variation - meiosis

Lecture Origin of genetic variation – mutation

Tutorial Assessment Tutorial

Lecture Mutation; origin, pattern and implications

Lecture Molecular pathology – (I) The consequences of gene

mutation

SGT Karyotype Analysis

Lecture Molecular pathology – Functional assays

Lecture The future: mammalian cloning and uses of stem cells

Lecture Problem based learning. Genes in pedigrees

SGT Pedigree Analysis

Learning Outcomes Demonstrate a basic knowledge and understanding of:

5. The control of cell proliferation and death 6. The pattern of early human development from fertilisation to the onset of

organogenesis 7. The contribution of molecular biology to understanding of fundamental cellular

processes and disease 8. The patterns of inheritance and basic genetics 9. Human genetics and genetic disease 10. Present a short oral scientific communication

Demonstrate an ability to:

1. Present a written scientific communication

Assessment The module is assessed by a combination of written examination (25 MCQ, 4 short notes and 1 essay) and course work.

Examination: 75% (Semester 2) Course work: 25% (Semester 2)

The course work component will include the following:

Oral presentation and handout: 12.5% 500 word essay 12.5%

Linked modules Introduction to Biomedical Science 1.

Hours 30 Hours (22hr Lectures; 4hr seminar; 4hr tutorial)

BMedSc Bachelor of Medical Science Year 1 Modules: Cardiovascular and Respiratory System 1

Module Description The content of this module is to some extent based on material covered in Introduction to Biomedical Science and Neuroscience, for example dealing with membrane potentials, action potentials, structure and function of muscle types and structure and functioning of the autonomic system. The module provides an essential foundation for Cardiovascular & Respiratory Science 2 (Yr 2) which deals with more complex integration of the cardiovascular and respiratory systems.

Module Content

Session Session Title

Lecture Introduction to the CVS System

Lecture Overview of the CVS System

Lecture Electrical Activity of the Heart

Lecture Basic Anatomy of the Heart

AnatPrac Topography of the Heart 1 and 2

Lecture Cardiac Cycle

Lecture Introduction to the ECG

SGT Cardiac Action Potentials & Conduction

Prac ECG Practical

Prac ECG Practical Feedback

Lecture Cardiac Cycle

Lecture Regulation of Output

AnatPrac Histology of Heart and Blood Vessels 1 and 2

Lecture Blood – Structure

Lecture Blood - Haemostasis

Lecture Basic Haemodynamics

Lecture Functional Properties of arterioles

SGT Composition of Blood

Lecture Arterioles

Lecture Capillaries

Lecture Venules and Veins

SGT Central venous pressure and cardiac output

SGT Vascular function and capillaries

Lecture Reflex Regulation of CVS

Lecture Basic anatomy of the respiratory system

AnatPrac Topography, Thorax Lower Airways

Lecture Role of Cardiovascular Reflexes in Everyday Life

AnatPrac Topography, Nasal Cavity, Upper Airways

SGT Control of the Cardiovascular System

Lecture Introduction to Respiratory Physiology

Lecture Volumes & Pressures

Prac Blood Pressure Practical

Prac Blood Pressure Practical Feedback Session

Prosect CVS & DIG Prosection

SGT Mechanics of Breathing

Lecture Compliance & Resistance

AnatPrac Histology of the Respiratory System 1 and 2

SGT Mechanics of Breathing 2

Lecture Alveolar Gases & Diffusion

SGT Elastic properties of the lungs

Prac Lung Function

Prac Lung Function Feedback Session

Lecture Blood Gas Transport - Oxygen

Lecture Carbon Dioxide Transport & Acid Base Balance

SGT Alveolar Gases and Diffusion

SDL CVRS Practicals Revision Session (Discussion Board)

SGT Blood Gas Transport

Exam In-course Assessment

Lecture Ventilation & Perfusion

SGT Ventilation and perfusion mismatch

Lecture Lung volumes beyond spirometry

SGT Review of the cardiovascular and respiratory systems

Lecture Formative assessment session

Learning Outcomes By the end of the module the student will be able to demonstrate:

1. A good knowledge of the anatomy of the component parts of the cardiovascular and respiratory systems and recognise the relationships between structure and function.

2. An awareness of how the functioning of the cardiovascular and respiratory system is integrated and how activity of the dual system is regulated.

3. An understanding of the anatomy and electrical activity of the heart (including the theoretical basis of the ECG) and the influence of nerves, hormones and drugs on it.

4. An understanding of the pressure and volume changes within the heart and pressure changes within the aorta during cardiac cycle and the factors regulating cardiac output.

5. An understanding of the functional roles for different types of blood vessels and how these relate to their structure and location in the body.

6. An understanding of the factors that govern alveolar ventilation in health and disease.

7. An understanding of the role of the respiratory system in the control of blood gases and pH, including how normal levels are maintained and the causes and consequences of disturbances.

Assessment The module is assessed by a combination of a written examination (25 MCQ, 4 short notes & 2 essay questions) and course work. Examination 75% (Semester 2) Course work 25% (Semester 2) The course work component will include the following: Short-answer questions test on practical work 12.5% Data interpretation questions 12.5% Hours 55 Hours (26x1hr lectures, 11x1hr tutorials, 2x2hr practical, 1x3hr practical, 5x2hr anatomy tutorial, 1x1hr prosection session)

BMedSc Bachelor of Medical Science Year 1 Modules: Digestive System Module Description The processes of digestion, absorption and excretion in the gastro-intestinal tract and associated organs are introduced to provide a system-based appreciation of specific function/dysfunction. The Module content links Introduction to Biomedical Sciences I, Biochemistry, Molecules & Movement, and Neuroscience 1 (all Level 1 Modules). Module Content

Session Session Title

Lecture Introduction and Overview of the Digestive System

Lecture Gross Anatomy of the Digestive System

Lecture Functions of the mouth/oesophagus and associated diseases

Prosect CVS & DIG Prosection

Lecture Secretion in the stomach and its control

AnatPrac Histology of the Gut Wall and Glands

Lecture Secretion in the pancreas and intestines

Lecture Control of Smooth Muscle in GI Tract

Lecture Motility in the GI Tract

Lecture Function of the Liver and Hepatobiliary System

Lecture Jaundice

Lecture Absorption of Specific Nutrients Ions and Water

SGT Digestion 1

Lecture Control and Absorption of Iron

Lecture Digestion and Absorption of Carbohydrate and Protein

SGT DIgestion 2

Lecture Digestion and Absorption of Specific Nutrition: Fat

Lecture Fed/fasted states and Metabolic Disorders

Exam Essay

SGT Digestion 3

Lecture Glycogen synthesis and breakdown

Lecture Nutrition 1: Normal physiology

SGT Digestion 4

Lecture Nutrition 2: Starvation/Obesity

Lecture Acute and Chronic Inflammation of the GIT

Lecture Cancers of the GIT

Exam Turning Point Formative MCQ

Exam Assessment Session

Learning Outcomes At the end of the course students will have obtained knowledge of:

1. Understand the gross anatomy of the organs of the digestive system, and demonstrate an understanding of their functions and processes.

2. Appreciate the mechanisms of digestion, motility, absorption and elimination as applied to the major organs and classes of food.

3. Understand the role of food in society, of nutrition and disordered nutrition and metabolic disturbance in diabetes.

4. They will have developed study skills and be able to use independent thought processes to discuss and evaluate scientific material.

Assessment

The module is assessed by a combination of a written examination (4 short notes & 2 essay questions) and course work (MCQ assessment and formal essay .

Examination 75% (Semester 2) Course work 25% (Semester 2) The course work component will include the following:

MCQ Assessment 12.5% 1 essay (1000 words) 12.5%

Hours 29 Hours (22x1hr lectures, 4x1hr tutorials, 1x2hr practical/demonstration, 1x1hr prosection demonstration, 1x1hr assessment session)

BMedSc Bachelor of Medical Science Year 1 Modules: Pharmacology

Module Description The module aims to familiarise the students with the principles of pharmacology as a quantitative science. Coverage of the basic principles is supported by a systems based consideration of the potential mechanisms for the pharmacological manipulation of the peripheral and central nervous systems, the gastrointestinal tract, inflammatory processes, infection and cancer. Module Content

Session Session Title

Lecture Principles of Drug Action

Lecture Introduction to Quantitive Pharmacology

Tutorial Tutorial 1

Lecture Pharm Methods & Meas

Lecture Drugs Affecting the Neuromuscular Junction

Lecture Absorption and Distribution of Drugs

Lecture Local Anaesthetics

Tutorial Tutorial 2

Lecture Drug Metabolism and Excretion

Lecture Introduction to Autonomic Pharmacology

Lecture Drugs Affecting the Parasympathetic Nervous System

Tutorial Tutorial 3

Lecture Adrenergic Pharmacology 1

Lecture Adrenergic Pharmacology 2

Lecture Beva Adrenoreceptor Blocking Drugs

SGT Autonomic Function and Dysfunction

ComPrac Cardiolab 1

Lecture Anti-Cholinesterases

Tutorial Tutorial 4

Lecture Gastrointestinal Tract

Lecture Anti-ulcer drugs

Lecture Histamine and Histamine Receptor Antagonists

Lecture Emetics and anti-drugs

Lecture Cardilab assessment

Tutorial Tutorial 5

Lecture Pharmacokinetics 1

Lecture Pharmacokinetics 2

StuPres Presentations

Lecture General Anaesthetics

Tutorial Tutorial 6

Lecture Opiate etc

Lecture Non-steroidal anti imflam drugs

Lecture Alcohol

Lecture Steroids

Lecture Cytotoxic drugs -

Tutorial Tutorial 7

Lecture Anti-bac chemo

Tutorial Tutorial 8

Lecture Adverse drug reactions

Lecture Principles in chemotherapy

Tutorial Tutorial 9

Lecture Anti-vrial chemo

Lecture Anti-parasitic chemo

Prac Drugs Affecting the Isolated Ileum of the Guinea-Pig

Learning Outcomes By the end of the module the student will be able to:

1. Understand the concept of a drug receptor and appreciate the nature of these receptors

2. Be able to define the terms agonist, antagonist, partial agonist, affinity and efficacy, and understand the importance of these parameters in determining the properties of drugs

3. Realise the importance of pharmacokinetics in influencing the response to a drug 4. Know the mechanisms of action and side effects of the main drugs affecting a)

the peripheral nerves, b) the central nervous system, c) the gastrointestinal tract, d) inflammatory processes and e) infectious organisms and cancer cells

5. Appreciate the ways in which differences between individuals can influence the response to, and toxic effects of, drugs

6. Be able to follow detailed instructions to perform simple, quantitative experiments to determine the effects of drugs and be able to present and interpret the data.

7. Work effectively in a group, and be able to present information orally

Assessment The module is assessed by a combination of a written examination (25 MCQ, 4 short notes & 2 essay questions) and course work.

Examination 75% (Semester 2) Course work 25% (Semester 2)

The course work component will include the following:

2 practical write-ups 6.25% each Group seminar presentation 6.25% MCQ tests in tutorial sessions 6.25%

Hours 50 Hours (31x 1hr lectures, 9x 1hr tutorials, 1 laboratory practical, 1 computer practical, 1 problem based learning session and 1 oral presentation).

BMedSc Bachelor of Medical Science Year 1 Modules: Infection 1

Module Description Classification of microorganisms; selection of specific examples which demonstrate principles of structure, growth and metabolism and concepts of antiviral chemotherapy and prevention of disease. The module is linked to Introduction to Biomedical Science I and II reflecting the cell and organ-specific tropisms of different microorganisms and to Pharmacology I through mechanisms of drug action. Module Content

Session Session Title

Lecture Introduction to the Course

Lecture Basic structure of bacterial cells

Lecture Growth and nutrition of Bacteria

Lecture Genetics of bacteria

Lecture Symbiosis/Normal flora

Lecture Bacterial Infections & Pathological Consequences

Lecture Antibiotics

Lecture Bacteria and the Immune Response

Lecture Epidemiology of Infectious Disease

LabPrac Practical

Tutorial Tutorial 1

Lecture What is a Virus 1

Lecture What is a Virus 2

Lecture Protein Composition and Morphology

Lecture Virus nucleic acids composition and structure

Lecture Classification of Viruses

Tutorial Tutorial 2

Lecture Human Viruses Infections

Lecture RNA Viruses Clinical Features and Replication

Lecture DNA Viruses Clinical Features and Replication

Tutorial Tutorial 3

Lecture Epidemiology

Learning Outcomes By the end of the module the student will be able to demonstrate and:

1. Understand the fundamentals of classification 2. Appreciate the distinctive features of viruses and bacteria 3. Show knowledge of infections important in human disease 4. Understand the replication strategies of viruses and growth of bacteria. 5. Demonstrate knowledge of prevention and treatment of human infections.

Assessment The module is assessed by a combination written examination (25 MCQ, 4 short notes & 1 essay question) and course work.

Examination 75% (Semester 2) Course work 25% (Semester 2) The course work component will include the following:

1x 500 word essay 12.5% Practical write-up 12.5% Hours 26 Hours (Bacteriology - 10 x 1hr lectures, 2 x 2hr practicals, 1 x 1hr tutorial

Virology - 9 x 1hr lectures, 2 x 1hr tutorials)