Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

15
Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG

Transcript of Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

Page 1: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

Blood Pressure and Sound (2)

Dept. of Biomedical Engineering2003200449

YOUNHO HONG

Page 2: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

IBP ( Invasive BP ) measurement

t

Pi

catheterBloodvessel

Pi

pill up withsome liquid(ex.saline)

diaphragm

strain gages

cablePo

t

Po

If we choose sticky and dense liquid, We can’t get the signal of Pi just like the graph.To get the signal, We should concern with distance, diameter of a catheter and liquid, air-bubble inside a catheter.

Page 3: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

IBP ( Invasive BP ) measurement

# Equivalent Circuit Model Of Catheter-Sensor System

(1) Resistance

AL

A

LVRRiV

, : resistance Electrical

resistivity

P1

P2

)21( PPF R

FRop : resistance Liquid

A

LR

viscosity

Page 4: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

IBP ( Invasive BP ) measurement

(2) Capacitance or Compliance

x

AC

dt

dvCi ,

dt

dpCf modulus sYoung'

YC

(3) Inductance or Inertance

dt

diLV

2 ,

A

mL

dt

dfLP

Page 5: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

IBP ( Invasive BP ) measurement

multiphysics Electric Circuit Fluid Mechanics

voltagecurrentcharge

pressure flow volume

dtdVI

C

dtdIV

L

A

L

I

VR

)( ][

modulus sYoung'

)(

)8

( ][

2

43

C

r

L

dtdFP

L

r

Lm

sPaF

R

Page 6: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

Equivalent Circuit Model of IBP

catheterPi

liquid

diaphragm

strain gages

cablePo

L c

C d

R c

Vi

Compliance of diaphragm

+Vo -

i

ODEorder 2nd :

20

20

0

00

dt

VdCL

dt

dVCRVV

dt

dVCiV

dt

diLiRV

dcdci

dcci

)()(]12

[

operator :

2

2

tKVtVW

D

W

D

dt

dD

ionn

dc

n

c

dc

CLW

L

CRK

1

2 ,1

dampingratio

naturalfrequency

Page 7: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

Equivalent Circuit Model of IBP

(1) Frequency Transfer Function

nnnn

i

o

Ww

jWw

Wjw

WjwjwV

jwVjwH

2)(1

1

12)(

1

)(

)()(

22

)2

(tan

)(4])(1[

1

))(1

2

(tan

)(4])(1[

1)(

1

2222

2

1

2222

w

W

Ww

Ww

Ww

WwWw

Ww

Ww

jwH

n

nnn

n

n

nn

Page 8: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

Equivalent Circuit Model of IBP

w

|H|

Wn

)dunderdampe( 5.0

)damped critically( 1

)overdamped( 2

w

-π/2

∠H)dunderdampe( 5.0

)damped critically( 1

)overdamped( 2

Page 9: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

Equivalent Circuit Model of IBP

Methods to solve 2nd order ODE io VV

dt

dVRC

dt

VdLC 0

20

2

function transfer loperationa : 1

1)(

dt

d )1(

)1(

2

2

2

RCDLCDV

VDH

DVVRCDLCD

VVRCDVVLCD

i

o

io

iooo

jwD

i

o

iooo

DH

jwRCjwLCV

VjwH

VVRCjwVVjwLC

)(

1)()(

1)(

)( )2(

2

2

Page 10: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

Steady State Freq. Response

)4

2sin()(

)2sin()(

1

1

tfKAtV

tfAtV

o

i

|H|

ff1 f2

K

0.5

)8.12sin(5.0)(

)2sin()(

2

2

tfAtV

tfAtV

o

i

f2f1

-4/π

-1.8π

∠H

Page 11: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

Unit Step ResponseIn reality, We need a unit step function for a starting point.

For example, should be )()2sin()( 1 tutfAtVi )2sin()( 1tfAtVi

input signal

underdamping

critical damping

overdamping

Page 12: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

Transient Step Response

Pbulb

balloon

saline

Po

underdamping

critical damping

overdamping

Page 13: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

Example(7.1) A 5mm-long air bubble has formed in the rigid-walled catheter to a Statham P23Dd sensor. The catheter is 1m long, 6 French diameter, and filled with water at 20 ℃. Plot the frequency-response curve of the system with and without the bubble.

033.0)(4

91)1

(2

21

3

21

P

VL

r

HzL

P

L

rfn

137.0

22,

bub

bubn Hzf

log f1.34 1.95

Page 14: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

Example(7.2) By changing only the radius of the catheter, redesign the (no-bubble) catheter of Figure 7.9 to achieve the damping ratio ζ=1. Calculate the resulting natiral frequency fn.

Hzf

rrff

r

r

rr

n

nn

29

147.0

0032.0

00

3

03

03

log f1.46

Page 15: Blood Pressure and Sound (2) Dept. of Biomedical Engineering 2003200449 YOUNHO HONG.

Thank you.