Bio-decontamination System · Isolator integration kit without PLC. Utilizes Isolator PLC to...
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1 BioVap TM Bio-decontamination System • Primary Healthcare Facilities • Pharmaceutical Science Behined the Pocess The Esco BioVap™ system is a process of atomizing the hydrogen peroxide sterilant creating a dry fog as it is injected into the space. This unique system (patent pending) creates a charge on the atomized droplets as it passes through the nozzle. This charge imparted on the droplets of sterilant creates two important synergies a. Each droplet of the sterilant contains billions of reactive molecules to execute the microbial kill. b. Through mutual repulsion, the droplets repel each other and distribute quickly through the space achieving a superior distribution of the sterilant. The charged droplets are attracted to the uncharged surfaces within the space so on impact the droplets burst and immediately start the sterilisation process. Due to these important factors, the sterilant used is minimised and can be of less concentration than the conventional vaporising systems that needed the sterilant to be evaporated first then wait for micro condensation to carry out the sterilization. This revolutionary bio-decontamination system is not affected by temperature or relative humidity therefore there is no requirement to precondition the space being bio- decontaminated and therefore leads to reduced cycle. Introduction Esco Pharma has developed an effective hydrogen peroxide based bio-decontamination system capable of achieving a log 6 reduction in bio-burden. The spore log reduction has been validated by biological indicator challenge using biological indicator stainless steel ribbons populated with Geobacillus stearothermophilus spores. This BioVap™ has been developed in response to increasing demands from the pharmaceutical, biotech, pharmacy, veterinary and other related industries for microbial free environments and more stringent decontamination requirements. Hydrogen peroxide breaks down into oxygen and water on completion of the sterilization process which makes it one of the most environment-friendly decontaminant available. The BioVap™ is developed for performing bio-decontamination of aseptic barrier system, pass through systems, biological safety cabinets, cleanrooms and virtually any other space where surface sterilization of bio- decontamination is required Industries Served • Hospital • Food, Beverages & Confectionary • Manufacturing Facilities • Veterinary Surgeries • Dentist SANITIZATION Two log-10 -2 DISINFECTION Five log-10 -5 STERILIZATION Six log-10 -6 1
Transcript of Bio-decontamination System · Isolator integration kit without PLC. Utilizes Isolator PLC to...
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BioVapTM
Bio-decontamination System
• PrimaryHealthcareFacilities
• Pharmaceutical
Science Behined the Pocess
TheEscoBioVap™system is aprocessof atomizing thehydrogenperoxidesterilantcreatingadryfogasitisinjectedintothespace.Thisuniquesystem(patentpending)createsachargeontheatomizeddropletsasitpassesthroughthenozzle.Thischargeimpartedonthedropletsofsterilantcreatestwoimportantsynergies
a. Eachdropletofthesterilantcontainsbillionsofreactivemoleculestoexecutethemicrobialkill.
b.Throughmutualrepulsion,thedropletsrepeleachotherand distribute quickly through the space achieving asuperiordistributionofthesterilant.Thechargeddropletsareattractedtotheunchargedsurfaceswithinthespacesoonimpactthedropletsburstandimmediatelystartthesterilisationprocess.
Duetotheseimportantfactors,thesterilantusedisminimisedandcanbe of lessconcentration than theconventionalvaporisingsystemsthatneededthesterilanttobeevaporatedfirst thenwait formicro condensation to carry out thesterilization.
This revolutionary bio-decontamination system is notaffectedbytemperatureorrelativehumiditythereforethereisno requirement toprecondition the spacebeing bio-decontaminatedandthereforeleadstoreducedcycle.
Introduction
EscoPharmahasdevelopedaneffectivehydrogenperoxidebasedbio-decontaminationsystemcapableofachievingalog6reductioninbio-burden.ThesporelogreductionhasbeenvalidatedbybiologicalindicatorchallengeusingbiologicalindicatorstainlesssteelribbonspopulatedwithGeobacillus stearothermophilusspores.
ThisBioVap™hasbeendevelopedinresponsetoincreasingdemandsfromthepharmaceutical, biotech,pharmacy,veterinaryandother related industries formicrobial freeenvironments and more stringent decontaminationrequirements.Hydrogenperoxidebreaksdownintooxygenandwater on completionof the sterilization processwhichmakesitoneofthemostenvironment-friendlydecontaminant available. The BioVap™ is developed forperformingbio-decontaminationofasepticbarriersystem,passthroughsystems,biologicalsafetycabinets,cleanroomsandvirtuallyanyotherspacewheresurfacesterilizationofbio-decontaminationisrequired
Industries Served
• Hospital
• Food,Beverages&Confectionary
• ManufacturingFacilities
• VeterinarySurgeries
• Dentist
SANITIZATION
Twolog-10-2
DISINFECTION
Fivelog-10-5
STERILIZATION
Sixlog-10-6
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BioVapTM
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Pre-Conditioning
Conventional Gaseous Systems
Gassing/Injection Dwell Aeration
Gassing/Injection
BioVapTM System
Dwell Aeration
Time
Flexibility Features
EscoPharmaBioVapTMsystemisdevelopedtobeflexibleenoughtoworkinallareas,fromcabinetsandtransferhatchesuptomodularenclosurestoisolatorkeepinginmindthateverycustomerandfacilityhasdifferentrequirements.
Image of the cleanroom / BSCnozzle assembly
Image of fixed nozzle in isolator
EscoPharmaTransferHatchandBioVapTMintegratedsystem
EscoPharmaBioVapTM
systemasapremiumsolutionfordecontaminationprocessforallsizesofbiosafetycabinets.
EscoPharmaBioVapTM
systemintegratedintotheisolatorasourapproachtoacosteffectivebio-decontamination.
EscoPharmaBioVapTMfoggingsystemasaneffectivebio-decontaminationforcleanroomandorlaboratory.
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BioVapTMHMIController
Process Step
TheBioVap™bio-decontaminationcyclewillhavethefollowingphases
a. InjectionPhase–Inthisphase,thesterilantisinjectedintothespaceasadryfogatapre-setpressureandflowrateandatagivenperiodoftime.Duringthisperiod,theatomisingpressure,injectionairflowandinjectionairpressurearemonitored.
b.DwellPhase-Duringthisphase,thesterilantisallowedtosettleonthesurfacesinsidetheenclosureforasetperiodoftime.
c. AerationPhase-Inthisphasethehydrogenperoxidesterilantisremovedfromthespace/enclosure.
Controls
TheBioVap™systemisPLCcontrolledwithoperatorinterfaceviaatouchscreenHMIterminalgivingoperatorlogonsecurityandrealtimedisplayofcycleparameters.Cycleparametersarealsorecordedandaprintoutofthecycleparametersisgivenattheendofacycleforvalidationrecords.Electronicdatarecordingofthecycles21CFR11compliantisavailableonrequest.20pre-programmedcyclescanbesavedonthePLCsystemselectablefromtheinterfaceterminal.TheBioVap™canbecontrolledlocallyviatheHMIlocatedontheBioVap™generatororcanbecontrolledremotelyfromanIsolatororcabinetcontrolsystem.
INNOVATIVE DESIGNGENERAL SPECIFICATIONS
Power Supply 240/110V,50/60Hzsinglephase
Air Supply 6barpressure200l/minflow(clean&dryair)
Sterilant 12%volhydrogenperoxide(100-400ul/minflow)
PLC SiemensS7-1200series
HMI SiemensTP170komfort
Printer Gebeticketlabelprinter
Spore Log Reduction UptoLog6
ORDERING INFORMATION
Option 1Isolator integration kit without PLC.
UtilizesIsolatorPLCtocontrol,monitorandreportonbio-decontamination.
Option 2Isolator integration kit with PLC
SystemcompletewithPLC,HMI&ticketprintermountedon304STSTenclosure
Option 3Mobile BioVapTM complete with PLC, HMI and printer.
Allhousedinwithinsturdymobilecase.Availablewithchoiceofnozzleassembly.
Nozzle Assembly A CleanroomNozzleAssembly
Nozzle Assembly B RemoteControlAssembly
CatalyticConverter
Adjustabletripodforbio-decontaminationofcleanroomandBSC
MobileBioVapTMSystemisfittedinsideahandycase
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LIVE SUPPORTescoglobal.com Esco Global Offices: Bahrain | Bangladesh | China | India | Indonesia | Italy | Japan
Malaysia | Philippines | Russia | Singapore | South Africa | South Korea | Thailand United Kingdom | USA | Vietnam
PLATFORMSPECIALIST.
Esco Pharma Pte Ltd21 Changi South Street 1 Singapore 486777 • Tel: +65 65420833Fax: +65 65426920 • Email: [email protected]
Esco Technologies, Inc.2512 Metropolitan Drive, Suite 120 BFeasterville- Trevose, PA 19053-6738Tel: 215 322 2155 • Email: [email protected]
Esco Gb LtdUnit 9, Century Park Networkcentre, Dearne Lane,Manvers, Rotherham, South Yorkshire, S63 5DE.Tel: +44 (0) 1709 761 669 • Email: [email protected]
Since 1978, Esco has emerged as a leader in the development of controlled environment, laboratory and pharmaceutical equipment solutions. Products sold in more than 100 countries include biological safety cabinets, fume hoods, ductless fume hoods, laminar flow clean benches, animal containment workstations, cytotoxic cabinets, hospital pharmacy isolators, and PCR cabinets and instrumentation. With the most extensive product line in the industry, Esco has passed more tests, in more languages, for more certifications, throughout more countries than any biosafety cabinet manufacturer in the world. Esco remains dedicated to delivering innovative solutions for the clinical, life science, research and industrial laboratory community. www.escoglobal.com.
PTEscoBintanIndonesiaCert.No:651333/E
EscoMicroPteLtdCert.No:651076
PTEscoBintanIndonesiaCert.No:Q2N130383797001
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Air ShowerAseptic Containment Isolator (ACTI)Ceiling Laminar Airflow UnitsCleanroom Transfer HatchContainment Barrier Isolator (CBI)Compounding Aseptic IsolatorCompounding Aseptic Containment IsolatorDownflow Booth (DFB)Dynamic Floor Label HatchDynamic Pass BoxEvidence Drying CabinetGarment Storage CabinetGeneral Processing Platform Isolator (GPPI)Healthcare Platform isolatorLaminar Flow Horizontal TrolleyLaminar Flow Straddle Units, Single and Double Laminar Flow Vertical TrolleyPass BoxSoft Wall CleanroomSputum BoothVentilated Balance Enclosure (VBE)Weighing and Dispensing Containment Isolator (WDCI)
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