An Overview of How Your Sleep and Biological Clock Affect Your Health

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• Prodigious biomedical research efforts into sleep, the natural daily period of sustained cessation of locomotor activity and overt consciousness, have defined a multitude of functions of this biological activity that regulate the life-long physical and mental health of the individual in numerous ways. • Sleep is the simple term for a very complex biological process involving multiple neural circuits in the brain that are orchestrated by circadian rhythm activities within the biological clock pacemaker system for the body, primarily located in the hypothalamus.

The role of sleep in our overall health• One such mechanism by which sleep regulates health appears to be that the neurophysiological activity of sleep, regulated by the biological clock, in turn programs the biological clock system to operate “normally”. The import herein is that the biological clock regulates all the major activities of the body such as behavior, metabolism, reproduction, and immunity.

The role of sleep in our overall health• Sustained disruptions to normal input signals to the biological clock system (perceived as “stress” by this neural clock network system) by any means (e.g., sustained altered sleep patterns, biochemical or environmental manipulation) alter regulatory output signals from the clock system to the body that can lead to major biological disturbances throughout the body.

The role of sleep in our overall health• Indeed sleep alterations such as reduced sleep, extended sleep, sleep apnea, and altered sleep patterns associated with shift work have all been associated with serious cardiometabolic disease. Moreover, studies indicate that the duration of sleep as well as the quality of sleep are each important factors in regulating metabolic health.

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Original Source:http://www.genengnews.com/keywordsandtools/print/3/40048/

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