Addressing Treatment Challenges in Cystic Fibrosis
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Transcript of Addressing Treatment Challenges in Cystic Fibrosis
Addressing Treatment Challenges in Cystic Fibrosis
Program Goals
Pseudomonas aeruginosa
Eradication of Mucoid Pseudomonas Infection
EPIC Clinical Trial*
EPIC Results
Management of Exacerbations
Cystic Fibrosis Guidelines
Cystic Fibrosis Guidelines
Why Don’t Physicians FollowClinical Practice Guidelines?
Personalized Medicine Targeting the CFTR
Strategies for Modifying the Underlying Defect in CF
Strategies for Modifying the Underlying Defect in CF (cont)
Ivacaftor in Patients With CF and the G551D Mutation
F508 (F508del)
Corrector TherapyPhase 2 Results of Lumacaftor + Ivacaftor
Looking to the Future
Will Improving CFTR Function Affect Chronic Pseudomonas
Infection?
Practical Advice to Address the Challenges of Complex Medical
Regimens
Abbreviations
References
References (cont)
References (cont)
References (cont)